| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Palmatine (chloride) perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Palmatine (chloride)_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.280566 |
| LAMC2 | laminin, gamma 2 | 0.0988617 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0987549 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0873392 |
| ANXA2 | annexin A2 | 0.0845926 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0773461 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0766692 |
| PLEC | plectin | 0.0740194 |
| DSPP | dentin sialophosphoprotein | 0.0672479 |
| LMO7 | LIM domain 7 | 0.0641699 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0620672 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0574975 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0556755 |
| AHNAK | AHNAK nucleoprotein | 0.0556552 |
| LAMB3 | laminin, beta 3 | 0.0547165 |
| NAV2 | neuron navigator 2 | 0.0544004 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0538604 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0518232 |
| MYO5B | myosin VB | 0.0506378 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0490329 |
| FN1 | fibronectin 1 | 0.0482631 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.046914 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.046644 |
| CTSB | cathepsin B | 0.0454975 |
| SMAD3 | SMAD family member 3 | 0.0453409 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0438764 |
| VGLL3 | vestigial-like family member 3 | 0.0433486 |
| SQSTM1 | sequestosome 1 | 0.0430593 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.042583 |
| ERBIN | erbb2 interacting protein | 0.0423066 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0416463 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0415599 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0407997 |
| ASPH | aspartate beta-hydroxylase | 0.0397224 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0395281 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0394892 |
| PGBD5 | piggyBac transposable element derived 5 | 0.0391053 |
| RASAL2 | RAS protein activator like 2 | 0.0387289 |
| EFNA5 | ephrin-A5 | 0.0387118 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0385848 |
| MYO6 | myosin VI | 0.0385631 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.038358 |
| CD44 | CD44 molecule (Indian blood group) | 0.0377404 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0376791 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0373989 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0360474 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0346774 |
| SVIL | supervillin | 0.0343222 |
| EGFR | epidermal growth factor receptor | 0.0343107 |
| PTK2 | protein tyrosine kinase 2 | 0.0341639 |
| VCL | vinculin | 0.0322096 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0321162 |
| TJP1 | tight junction protein 1 | 0.0316271 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0316184 |
| DSG2 | desmoglein 2 | 0.0312502 |
| FLNB | filamin B, beta | 0.0307929 |
| ANO6 | anoctamin 6 | 0.030689 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0304795 |
| ENO1 | enolase 1, (alpha) | 0.0303544 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0303281 |
| HDAC9 | histone deacetylase 9 | 0.0303255 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0302433 |
| RUNX1 | runt-related transcription factor 1 | 0.0299052 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.02988 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0297308 |
| MYO10 | myosin X | 0.0297092 |
| DST | dystonin | 0.0294938 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0291485 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0289654 |
| ATXN1 | ataxin 1 | 0.0287213 |
| FHIT | fragile histidine triad | 0.0287067 |
| KIAA1217 | KIAA1217 | 0.0286142 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0278065 |
| KRT19 | keratin 19, type I | 0.0276054 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0275676 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0272545 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides | 0.0272002 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | 0.0270459 |
| PLSCR1 | phospholipid scramblase 1 | 0.0269482 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0268448 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0265209 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0264849 |
| OGA | O-GlcNAcase | 0.0263087 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0261018 |
| SGMS2 | sphingomyelin synthase 2 | 0.0260258 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0259753 |
| SEPTIN9 | septin 9 | 0.025882 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0256014 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0254305 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0251211 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0249478 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0249425 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0247426 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0247099 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0244644 |
| CNKSR3 | CNKSR family member 3 | 0.0242076 |
| FAM107B | family with sequence similarity 107, member B | 0.0241651 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.0239192 |
| MYO1E | myosin IE | 0.0238442 |
| DTNA | dystrobrevin, alpha | 0.0236733 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.22536 |
| FTL | ferritin, light polypeptide | -0.211368 |
| PTMA | prothymosin, alpha | -0.190653 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.114856 |
| RPL35A | ribosomal protein L35a | -0.114498 |
| NDRG1 | N-myc downstream regulated 1 | -0.0904407 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0888023 |
| RPS19 | ribosomal protein S19 | -0.0834143 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.080976 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0743486 |
| RPS6 | ribosomal protein S6 | -0.0701127 |
| RPS23 | ribosomal protein S23 | -0.0649061 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0581719 |
| POTEF | POTE ankyrin domain family, member F | -0.0576738 |
| RPLP2 | ribosomal protein, large, P2 | -0.0560703 |
| RPLP1 | ribosomal protein, large, P1 | -0.0554405 |
| RPL8 | ribosomal protein L8 | -0.0551856 |
| RPL34 | ribosomal protein L34 | -0.0550727 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0546845 |
| RNF145 | ring finger protein 145 | -0.0546659 |
| GOLGA4 | golgin A4 | -0.0521122 |
| S100A6 | S100 calcium binding protein A6 | -0.0519592 |
| RPL32 | ribosomal protein L32 | -0.0516805 |
| RPL23 | ribosomal protein L23 | -0.0502579 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0496579 |
| ACTG1 | actin gamma 1 | -0.0487214 |
| SLC38A1 | solute carrier family 38, member 1 | -0.048526 |
| RPS14 | ribosomal protein S14 | -0.0451342 |
| RPS13 | ribosomal protein S13 | -0.0448736 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.043843 |
| RBM25 | RNA binding motif protein 25 | -0.0438211 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0432389 |
| RACK1 | receptor for activated C kinase 1 | -0.0418508 |
| GNAS | GNAS complex locus | -0.0417565 |
| RPS29 | ribosomal protein S29 | -0.0406821 |
| RPS8 | ribosomal protein S8 | -0.040075 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0394386 |
| S100A10 | S100 calcium binding protein A10 | -0.038979 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0388394 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0387465 |
| RPL31 | ribosomal protein L31 | -0.0382693 |
| FAM13A | family with sequence similarity 13, member A | -0.0373217 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0369579 |
| RPL5 | ribosomal protein L5 | -0.0368268 |
| TMSB4X | thymosin beta 4, X-linked | -0.0359681 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.03564 |
| DSTN | destrin (actin depolymerizing factor) | -0.0351084 |
| RPS25 | ribosomal protein S25 | -0.0347606 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0345446 |
| RPL37A | ribosomal protein L37a | -0.0343959 |
| RPS3 | ribosomal protein S3 | -0.0338869 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.033807 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0333522 |
| VIM | vimentin | -0.0331949 |
| TOP1 | topoisomerase (DNA) I | -0.0331508 |
| TMEM165 | transmembrane protein 165 | -0.0330068 |
| RPL28 | ribosomal protein L28 | -0.0328615 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0320074 |
| RPL15 | ribosomal protein L15 | -0.0319524 |
| RPS21 | ribosomal protein S21 | -0.0319251 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0315698 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0312299 |
| MATR3 | matrin 3 | -0.0311054 |
| RPS17 | ribosomal protein S17 | -0.0310873 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0310292 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0309815 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0308905 |
| TFG | TRK-fused gene | -0.0305818 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0301207 |
| RPS24 | ribosomal protein S24 | -0.0299548 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0299159 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0298687 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0298174 |
| RPL36A | ribosomal protein L36a | -0.029705 |
| HMGA1 | high mobility group AT-hook 1 | -0.0293625 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.029114 |
| CTSD | cathepsin D | -0.0288998 |
| RPL9 | ribosomal protein L9 | -0.0285165 |
| RPS27 | ribosomal protein S27 | -0.0284006 |
| WASF2 | WAS protein family, member 2 | -0.028371 |
| RPS16 | ribosomal protein S16 | -0.0283514 |
| UPP1 | uridine phosphorylase 1 | -0.0281047 |
| VEGFA | vascular endothelial growth factor A | -0.0280882 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0278876 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0275195 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0271621 |
| RPS12 | ribosomal protein S12 | -0.0269053 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0265672 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0265475 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0262177 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0261667 |
| CCNL1 | cyclin L1 | -0.0259491 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0258991 |
| PFN1 | profilin 1 | -0.0258934 |
| RPS10 | ribosomal protein S10 | -0.0253597 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0250688 |
| RPS5 | ribosomal protein S5 | -0.0247566 |
| RPL19 | ribosomal protein L19 | -0.0246952 |
| RPS15 | ribosomal protein S15 | -0.024633 |
| MXD1 | MAX dimerization protein 1 | -0.0243294 |
