| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Palmatine (chloride) perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Palmatine (chloride)_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | 0.1798 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.132352 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.111295 |
| PDE10A | phosphodiesterase 10A | 0.106874 |
| DST | dystonin | 0.104157 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | 0.101937 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.101878 |
| COL5A2 | collagen, type V, alpha 2 | 0.0939824 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0888354 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0841834 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0793941 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0790125 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0780588 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0775961 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0760221 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0738554 |
| PCBP2 | poly(rC) binding protein 2 | 0.0705057 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0696945 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0693164 |
| MAP7 | microtubule-associated protein 7 | 0.0608016 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0594988 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0593708 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0580093 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0573114 |
| INTS6 | integrator complex subunit 6 | 0.0568477 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0565521 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.055383 |
| FMNL2 | formin-like 2 | 0.0551718 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0551214 |
| AUTS2 | autism susceptibility candidate 2 | 0.0539216 |
| SMAD2 | SMAD family member 2 | 0.0532726 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0524985 |
| PDE7B | phosphodiesterase 7B | 0.0519416 |
| MCL1 | myeloid cell leukemia 1 | 0.0518095 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0502594 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0488961 |
| RAD51B | RAD51 paralog B | 0.0436436 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0421116 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0414826 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0414591 |
| CHL1 | cell adhesion molecule L1-like | 0.0413267 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0410285 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0405333 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0403102 |
| NCOR2 | nuclear receptor corepressor 2 | 0.039342 |
| LSAMP | limbic system-associated membrane protein | 0.0393185 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0391391 |
| XYLT1 | xylosyltransferase I | 0.0386712 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0382016 |
| ITPK1 | inositol-tetrakisphosphate 1-kinase | 0.0379519 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0377097 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0376272 |
| VCL | vinculin | 0.0371172 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.0367288 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0366892 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0361221 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0351483 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0351248 |
| NRXN3 | neurexin 3 | 0.0345363 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0345198 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.034267 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0341896 |
| CTBP2 | C-terminal binding protein 2 | 0.0338804 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0334142 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0326403 |
| CADM2 | cell adhesion molecule 2 | 0.0321537 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0320955 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0317383 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0315782 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0315121 |
| RAB3B | RAB3B, member RAS oncogene family | 0.0312761 |
| ATXN1 | ataxin 1 | 0.0307684 |
| FTL | ferritin, light polypeptide | 0.0304275 |
| POTEF | POTE ankyrin domain family, member F | 0.0304033 |
| MT2A | metallothionein 2A | 0.029942 |
| EPHA4 | EPH receptor A4 | 0.0298537 |
| GREM2 | gremlin 2, DAN family BMP antagonist | 0.0298198 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0288374 |
| NRDC | nardilysin convertase | 0.0287611 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0284021 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0280903 |
| PCDH15 | protocadherin-related 15 | 0.0280457 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0280186 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0277535 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0275898 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0274056 |
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | 0.027187 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0270405 |
| NHSL1 | NHS-like 1 | 0.0270219 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0270056 |
| SEPTIN9 | septin 9 | 0.0269536 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0266478 |
| KYNU | kynureninase | 0.0263116 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0258323 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0255766 |
| HDAC4 | histone deacetylase 4 | 0.0252338 |
| RAB31 | RAB31, member RAS oncogene family | 0.0251858 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0250821 |
| ITGA6 | integrin, alpha 6 | 0.0250404 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0250259 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.230051 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.186549 |
| EFNA5 | ephrin-A5 | -0.127774 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.115255 |
| FN1 | fibronectin 1 | -0.110433 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.102828 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.10232 |
| TXNRD1 | thioredoxin reductase 1 | -0.0894314 |
| NRCAM | neuronal cell adhesion molecule | -0.0755368 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0738716 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.072407 |
| TMSB10 | thymosin beta 10 | -0.0723624 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0701123 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0683144 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0650383 |
| RPS24 | ribosomal protein S24 | -0.0535716 |
| ASPH | aspartate beta-hydroxylase | -0.0514194 |
| INHBA | inhibin, beta A | -0.0488372 |
| PGK1 | phosphoglycerate kinase 1 | -0.0483109 |
| HLA-B | major histocompatibility complex, class I, B | -0.0473586 |
| BMERB1 | bMERB domain containing 1 | -0.0454249 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0453014 |
| TMSB4X | thymosin beta 4, X-linked | -0.0425453 |
| CANX | calnexin | -0.0420905 |
| OSMR | oncostatin M receptor | -0.0413788 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0411717 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0389282 |
| RPL4 | ribosomal protein L4 | -0.0388331 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0385233 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0374712 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0367207 |
| PCBP3 | poly(rC) binding protein 3 | -0.0337522 |
| COL4A5 | collagen, type IV, alpha 5 | -0.033666 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0333593 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.033056 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0319574 |
| RPL34 | ribosomal protein L34 | -0.0313903 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0306987 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0306543 |
| AHNAK | AHNAK nucleoprotein | -0.0300669 |
| RPS21 | ribosomal protein S21 | -0.0297489 |
| TNPO1 | transportin 1 | -0.0296614 |
| ARF1 | ADP-ribosylation factor 1 | -0.0296416 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0292046 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0291043 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0289876 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0286293 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | -0.0283825 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0283781 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0280979 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0280016 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0277189 |
| HDLBP | high density lipoprotein binding protein | -0.0275559 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0274369 |
| PTMA | prothymosin, alpha | -0.0271516 |
| SEPTIN10 | septin 10 | -0.0270754 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0268093 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0267876 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.026773 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0266304 |
| SLFN5 | schlafen family member 5 | -0.0265708 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.0262108 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.026052 |
| TBXT | T-box transcription factor T | -0.0260068 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0259796 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0255978 |
| RPL26 | ribosomal protein L26 | -0.0255027 |
| SLC16A6 | solute carrier family 16, member 6 | -0.0254532 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0252197 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0252026 |
| RPL38 | ribosomal protein L38 | -0.0248368 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0248253 |
| RRBP1 | ribosome binding protein 1 | -0.0247531 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.024403 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0242645 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0239162 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0238257 |
| CD44 | CD44 molecule (Indian blood group) | -0.0231631 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0231393 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -0.0231083 |
| STC1 | stanniocalcin 1 | -0.0230937 |
| RPL35A | ribosomal protein L35a | -0.0230598 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0229983 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0224055 |
| RPS6 | ribosomal protein S6 | -0.0223895 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0222204 |
| ENO1 | enolase 1, (alpha) | -0.0222125 |
| CEP95 | centrosomal protein 95kDa | -0.0220685 |
| ABLIM1 | actin binding LIM protein 1 | -0.0213569 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0212533 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0211116 |
| ENAH | enabled homolog (Drosophila) | -0.0210777 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0206604 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0205465 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0203399 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0203279 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0201758 |
| AFG2A | AFG2 AAA ATPase homolog A | -0.0200871 |
| PLCB4 | phospholipase C, beta 4 | -0.0199351 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0198532 |
