| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Palmatine (chloride) perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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198 genes differentially expressed following the Palmatine (chloride)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.178771 |
| MYO1E | myosin IE | 0.174662 |
| ANXA2 | annexin A2 | 0.156653 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.146616 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.137778 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.129536 |
| NPAS2 | neuronal PAS domain protein 2 | 0.127649 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.122699 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.122524 |
| SLTM | SAFB-like, transcription modulator | 0.117847 |
| EFNA5 | ephrin-A5 | 0.106059 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.10337 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.101646 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0971067 |
| LSAMP | limbic system-associated membrane protein | 0.0916687 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0906729 |
| CANX | calnexin | 0.0886993 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0870612 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0830294 |
| EGFR | epidermal growth factor receptor | 0.0814387 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0783092 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0761716 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0746192 |
| MED13L | mediator complex subunit 13-like | 0.0714625 |
| B2M | beta-2-microglobulin | 0.0707733 |
| FN1 | fibronectin 1 | 0.0697899 |
| NRG1 | neuregulin 1 | 0.0680157 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0676485 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0665594 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0659308 |
| PRELID2 | PRELI domain containing 2 | 0.0638344 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.063682 |
| EXOC4 | exocyst complex component 4 | 0.0629666 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0628388 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0620786 |
| TXNRD1 | thioredoxin reductase 1 | 0.058298 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0579098 |
| VCL | vinculin | 0.0573004 |
| PRKCA | protein kinase C, alpha | 0.0570335 |
| ZNF638 | zinc finger protein 638 | 0.0565908 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0547295 |
| SQSTM1 | sequestosome 1 | 0.0471589 |
| RBM39 | RNA binding motif protein 39 | 0.0454722 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0441931 |
| MYOF | myoferlin | 0.0434894 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0433188 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0430102 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0419773 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0417241 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0402508 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0402207 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0402034 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0394378 |
| FOXO3 | forkhead box O3 | 0.0384565 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0381908 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0379066 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0364645 |
| NDRG1 | N-myc downstream regulated 1 | 0.0352816 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0352323 |
| JMJD1C | jumonji domain containing 1C | 0.0332287 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0326928 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0320988 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0305582 |
| PTK2 | protein tyrosine kinase 2 | 0.0302677 |
| SMAD3 | SMAD family member 3 | 0.0300271 |
| LMO7 | LIM domain 7 | 0.028207 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0280978 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.027615 |
| FAM13A | family with sequence similarity 13, member A | 0.0268065 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.026667 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0244323 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0238651 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0231755 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0231501 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0216076 |
| SMYD3 | SET and MYND domain containing 3 | 0.0211765 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0209986 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.020073 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0199936 |
| DST | dystonin | 0.0199056 |
| RAD51B | RAD51 paralog B | 0.0170884 |
| FNIP1 | folliculin interacting protein 1 | 0.0138561 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0138494 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0121703 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0108322 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0102657 |
| MED13 | mediator complex subunit 13 | 0.0102374 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.00997739 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.00796373 |
| RPL11 | ribosomal protein L11 | 0.00777918 |
| CMIP | c-Maf inducing protein | 0.00774489 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.00732903 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.00729218 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.00430007 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.00417837 |
| PTMA | prothymosin, alpha | 0.00401387 |
| RPL19 | ribosomal protein L19 | 0.0025981 |
| BIRC6 | baculoviral IAP repeat containing 6 | 6.38921E-4 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.224666 |
| PDE10A | phosphodiesterase 10A | -0.176072 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.134613 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.111877 |
| IGF2 | insulin-like growth factor 2 | -0.109885 |
| DOCK4 | dedicator of cytokinesis 4 | -0.104063 |
| SBF2 | SET binding factor 2 | -0.0941551 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0919262 |
| TENM3 | teneurin transmembrane protein 3 | -0.0869678 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.085069 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0847074 |
| RAB10 | RAB10, member RAS oncogene family | -0.0801143 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0777736 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0763735 |
| RPLP1 | ribosomal protein, large, P1 | -0.0761379 |
| NFIA | nuclear factor I/A | -0.0758516 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0744746 |
| RSF1 | remodeling and spacing factor 1 | -0.0707931 |
| FMNL2 | formin-like 2 | -0.0695968 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0651704 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0639704 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0638523 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0582245 |
| RPS12 | ribosomal protein S12 | -0.0577023 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0564483 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0562419 |
| OGA | O-GlcNAcase | -0.0559761 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0553215 |
| HELZ | helicase with zinc finger | -0.0546259 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0539877 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0524203 |
| PKM | pyruvate kinase, muscle | -0.0510333 |
| RPS6 | ribosomal protein S6 | -0.0496322 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0482556 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0470076 |
| SMC5 | structural maintenance of chromosomes 5 | -0.0467604 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.046366 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0454183 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0441687 |
| GOLGA4 | golgin A4 | -0.0439566 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0439522 |
| ENO1 | enolase 1, (alpha) | -0.0430122 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0429281 |
| GPC6 | glypican 6 | -0.042905 |
| ANKRD12 | ankyrin repeat domain 12 | -0.04274 |
| RORA | RAR-related orphan receptor A | -0.0416628 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0375674 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0366613 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0364798 |
| STC1 | stanniocalcin 1 | -0.0362107 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0353155 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0349617 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0342291 |
| ACTG1 | actin gamma 1 | -0.033398 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0330295 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0320446 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0311462 |
| RPL34 | ribosomal protein L34 | -0.0304501 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0303444 |
| CCNI | cyclin I | -0.0302157 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0301052 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0300935 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0295277 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0293814 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.028878 |
| GPHN | gephyrin | -0.0274599 |
| PARD3 | par-3 family cell polarity regulator | -0.0274053 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.027147 |
| RNF213 | ring finger protein 213 | -0.0271038 |
| VIM | vimentin | -0.0257219 |
| RPS3 | ribosomal protein S3 | -0.0254168 |
| ZNF292 | zinc finger protein 292 | -0.0248957 |
| FLNB | filamin B, beta | -0.0248122 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0246522 |
| TUT4 | terminal uridylyl transferase 4 | -0.0236398 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0230712 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0230627 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0230373 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0229691 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0206437 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | -0.0205621 |
| EGR1 | early growth response 1 | -0.020326 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0198723 |
| PGK1 | phosphoglycerate kinase 1 | -0.019654 |
| DENND4A | DENN/MADD domain containing 4A | -0.0196129 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.019523 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0192413 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0182884 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0171453 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0170899 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0163208 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0162537 |
| RPL23 | ribosomal protein L23 | -0.0158192 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0147858 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0144295 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | -0.0140309 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0121549 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0121228 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0116852 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0116474 |
