| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Palmatine (chloride) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Palmatine (chloride)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL11A1 | collagen, type XI, alpha 1 | 0.22039 |
| CADM2 | cell adhesion molecule 2 | 0.182689 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.151065 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.129675 |
| TENM3 | teneurin transmembrane protein 3 | 0.1057 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0921509 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0907956 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.088415 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | 0.0879371 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0849698 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0831291 |
| PCDH9 | protocadherin 9 | 0.0786972 |
| MKI67 | marker of proliferation Ki-67 | 0.0783392 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0781163 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0729258 |
| CDH19 | cadherin 19, type 2 | 0.0698168 |
| CENPF | centromere protein F, 350/400kDa | 0.0685308 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0685205 |
| GPC3 | glypican 3 | 0.0679583 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0668475 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | 0.0605017 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0587708 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0587428 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0579145 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0573259 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0549409 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0530042 |
| COL3A1 | collagen, type III, alpha 1 | 0.0503602 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0502159 |
| PLPP1 | phospholipid phosphatase 1 | 0.0481022 |
| UTRN | utrophin | 0.0480555 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0478301 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.047212 |
| NPAS3 | neuronal PAS domain protein 3 | 0.0459589 |
| ZNF608 | zinc finger protein 608 | 0.0458652 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0458405 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0437973 |
| KIF4A | kinesin family member 4A | 0.0428143 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0419141 |
| DST | dystonin | 0.0412168 |
| SMC4 | structural maintenance of chromosomes 4 | 0.038995 |
| TOX | thymocyte selection-associated high mobility group box | 0.0389444 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0388587 |
| MEIS2 | Meis homeobox 2 | 0.0388474 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0387852 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0381669 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0377453 |
| METAP2 | methionyl aminopeptidase 2 | 0.0368981 |
| HDAC9 | histone deacetylase 9 | 0.0367804 |
| ARHGAP15 | Rho GTPase activating protein 15 | 0.0361528 |
| LRRC4C | leucine rich repeat containing 4C | 0.0344832 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0339937 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0324687 |
| COL5A2 | collagen, type V, alpha 2 | 0.0324641 |
| SP3 | Sp3 transcription factor | 0.0322516 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.032238 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0320332 |
| PLEKHG1 | pleckstrin homology domain containing, family G (with RhoGef domain) member 1 | 0.031911 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0318538 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0306644 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0306613 |
| SMYD3 | SET and MYND domain containing 3 | 0.0304497 |
| TPX2 | TPX2, microtubule-associated | 0.0301122 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0300707 |
| PLCB4 | phospholipase C, beta 4 | 0.0295943 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.029204 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.0289759 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0288591 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0286954 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0286362 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.028428 |
| CCDC102B | coiled-coil domain containing 102B | 0.0283748 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0279721 |
| PHF3 | PHD finger protein 3 | 0.0279439 |
| PRELID2 | PRELI domain containing 2 | 0.027619 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0275869 |
| FIGN | fidgetin | 0.0275866 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0274129 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0271733 |
| CCNA2 | cyclin A2 | 0.0268198 |
| CENPE | centromere protein E, 312kDa | 0.026564 |
| SHROOM3 | shroom family member 3 | 0.026453 |
| ZNF385D | zinc finger protein 385D | 0.0264206 |
| CDK6 | cyclin-dependent kinase 6 | 0.0262315 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0258736 |
| FOXP2 | forkhead box P2 | 0.0254807 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 0.0251309 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0248249 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0247517 |
| TEX11 | testis expressed 11 | 0.0247122 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0246357 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0242328 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0241403 |
| DIAPH3 | diaphanous-related formin 3 | 0.0240387 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0238993 |
| SCFD1 | sec1 family domain containing 1 | 0.0237573 |
| PCDH7 | protocadherin 7 | 0.0237488 |
| NCKAP1 | NCK-associated protein 1 | 0.0234655 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0234543 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0230493 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS6 | ribosomal protein S6 | -0.100745 |
| RPS8 | ribosomal protein S8 | -0.0683103 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0645011 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0639635 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0604131 |
| RPS16 | ribosomal protein S16 | -0.0585341 |
| PTMA | prothymosin, alpha | -0.0552511 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.053363 |
| RPS13 | ribosomal protein S13 | -0.052733 |
| TMSB10 | thymosin beta 10 | -0.0525077 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0483761 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0478377 |
| PFN1 | profilin 1 | -0.0473468 |
| RPL9 | ribosomal protein L9 | -0.043271 |
| COL1A2 | collagen, type I, alpha 2 | -0.0409973 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0406266 |
| RPS21 | ribosomal protein S21 | -0.040348 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0396963 |
| CALR | calreticulin | -0.0396316 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0391308 |
| PGK1 | phosphoglycerate kinase 1 | -0.0385822 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0358087 |
| SOX2 | SRY (sex determining region Y)-box 2 | -0.0334106 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0331283 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0328339 |
| RPL36 | ribosomal protein L36 | -0.0322581 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0319092 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.031349 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0312583 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0303514 |
| RPL28 | ribosomal protein L28 | -0.0301751 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0296167 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0295682 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0291923 |
| FAM177A1 | family with sequence similarity 177, member A1 | -0.0291114 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | -0.0288414 |
| JMJD1C | jumonji domain containing 1C | -0.0287801 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0285639 |
| TUT4 | terminal uridylyl transferase 4 | -0.0285002 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0281815 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0278868 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0272325 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0271564 |
| UPP1 | uridine phosphorylase 1 | -0.0266978 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0265568 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0262009 |
| FMNL2 | formin-like 2 | -0.0256251 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0255804 |
| RPS10 | ribosomal protein S10 | -0.0255608 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0254745 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0250615 |
| SRRM1 | serine/arginine repetitive matrix 1 | -0.0249626 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0246833 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0245304 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0240309 |
| RPL35A | ribosomal protein L35a | -0.0239555 |
| RPL34 | ribosomal protein L34 | -0.0239258 |
| RPS24 | ribosomal protein S24 | -0.0238317 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.0235678 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0232434 |
| ERP29 | endoplasmic reticulum protein 29 | -0.0229892 |
| RTN4 | reticulon 4 | -0.0228292 |
| FLNB | filamin B, beta | -0.0225268 |
| WASF2 | WAS protein family, member 2 | -0.0225017 |
| SNX6 | sorting nexin 6 | -0.0224336 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0224114 |
| COG5 | component of oligomeric golgi complex 5 | -0.0223821 |
| RPL37 | ribosomal protein L37 | -0.0223553 |
| RPL11 | ribosomal protein L11 | -0.0223399 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0221983 |
| RPL7A | ribosomal protein L7a | -0.0221943 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0221265 |
| MYADM | myeloid-associated differentiation marker | -0.0219182 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | -0.0218107 |
| RPL26 | ribosomal protein L26 | -0.0217993 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0217889 |
| H1-0 | H1.0 linker histone | -0.0217747 |
| S100A9 | S100 calcium binding protein A9 | -0.02173 |
| MYO10 | myosin X | -0.0215431 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0215293 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0214831 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase | -0.0212085 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.021044 |
| GDI1 | GDP dissociation inhibitor 1 | -0.0209543 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0209339 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.0208974 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0206965 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0206836 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0203921 |
| SRP54 | signal recognition particle 54kDa | -0.0203819 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0203115 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | -0.0202415 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0202344 |
| RPS2 | ribosomal protein S2 | -0.0200742 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0199075 |
| RPLP0 | ribosomal protein, large, P0 | -0.0198634 |
| YBX1 | Y box binding protein 1 | -0.0197963 |
| SKIC3 | SKI3 subunit of superkiller complex | -0.0197306 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0197248 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0196868 |
