| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Palmatine (chloride) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Palmatine (chloride)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STC1 | stanniocalcin 1 | 0.140914 |
| ANXA2 | annexin A2 | 0.0948953 |
| SMAD3 | SMAD family member 3 | 0.0881327 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0845211 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0785547 |
| SVIL | supervillin | 0.0759767 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0656058 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.064419 |
| TGM2 | transglutaminase 2 | 0.0641045 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.060808 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0511976 |
| CTSB | cathepsin B | 0.0482404 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0464536 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0463394 |
| CLIC4 | chloride intracellular channel 4 | 0.0446077 |
| FAT1 | FAT atypical cadherin 1 | 0.0442159 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0434352 |
| NRP1 | neuropilin 1 | 0.0428612 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0412604 |
| LDHA | lactate dehydrogenase A | 0.0409682 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0398682 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0397151 |
| TNNC1 | troponin C type 1 (slow) | 0.0388218 |
| COL5A3 | collagen, type V, alpha 3 | 0.0385509 |
| TMEM178B | transmembrane protein 178B | 0.0372049 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0361644 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0355323 |
| CD44 | CD44 molecule (Indian blood group) | 0.0355154 |
| PTK2 | protein tyrosine kinase 2 | 0.0353608 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.035089 |
| MX1 | MX dynamin-like GTPase 1 | 0.0344337 |
| HLA-E | major histocompatibility complex, class I, E | 0.0341559 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0338361 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0328179 |
| ECE1 | endothelin converting enzyme 1 | 0.0327268 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0322783 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0322293 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0318879 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0317452 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0310044 |
| IL6ST | interleukin 6 signal transducer | 0.0307902 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0307901 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0295175 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0294047 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0287919 |
| RIGI | RNA sensor RIG-I | 0.0285882 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0278666 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0276538 |
| IFI44L | interferon-induced protein 44-like | 0.0276113 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0275779 |
| ENO1 | enolase 1, (alpha) | 0.0273761 |
| DST | dystonin | 0.0270149 |
| FLNB | filamin B, beta | 0.0266968 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0264765 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0264415 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0264164 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0262456 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0260651 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0260428 |
| ARRDC3 | arrestin domain containing 3 | 0.0253203 |
| AOPEP | aminopeptidase O (putative) | 0.0252427 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0248513 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0246624 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0245642 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.024562 |
| PLAT | plasminogen activator, tissue | 0.0245544 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0244866 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0243008 |
| MED13L | mediator complex subunit 13-like | 0.0242349 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0240257 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0234609 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0234117 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.023077 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0229875 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.022971 |
| FRMD4A | FERM domain containing 4A | 0.0229123 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0228831 |
| UBC | ubiquitin C | 0.0227493 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0227456 |
| SMYD3 | SET and MYND domain containing 3 | 0.0226299 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0225465 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0224291 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0223431 |
| RPLP1 | ribosomal protein, large, P1 | 0.0222494 |
| HDAC8 | histone deacetylase 8 | 0.0221526 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0220822 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0220431 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0220316 |
| SQSTM1 | sequestosome 1 | 0.022022 |
| AFAP1 | actin filament associated protein 1 | 0.021814 |
| TRIM14 | tripartite motif containing 14 | 0.0217956 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0214974 |
| HPCAL1 | hippocalcin-like 1 | 0.0213231 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0212809 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0211815 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0209862 |
| TPM4 | tropomyosin 4 | 0.0207565 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0207555 |
| MSN | moesin | 0.0206341 |
| HELZ | helicase with zinc finger | 0.0204664 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL1A1 | collagen, type I, alpha 1 | -0.181746 |
| NDRG1 | N-myc downstream regulated 1 | -0.163357 |
| CDH13 | cadherin 13 | -0.11365 |
| COL6A2 | collagen, type VI, alpha 2 | -0.111616 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.102342 |
| TMSB10 | thymosin beta 10 | -0.100481 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0992805 |
| FN1 | fibronectin 1 | -0.0947422 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.065735 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0626107 |
| COL1A2 | collagen, type I, alpha 2 | -0.0608392 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0563547 |
| MMP12 | matrix metallopeptidase 12 | -0.0562136 |
| HLA-B | major histocompatibility complex, class I, B | -0.0562079 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0504713 |
| COL5A1 | collagen, type V, alpha 1 | -0.050461 |
| INHBA | inhibin, beta A | -0.0461557 |
| EML5 | echinoderm microtubule associated protein like 5 | -0.0450891 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0428797 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0416687 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0400945 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0381456 |
| TPM1 | tropomyosin 1 (alpha) | -0.0375707 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0369747 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.03571 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0353555 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0341623 |
| CD109 | CD109 molecule | -0.0335786 |
| VCAN | versican | -0.0335655 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0335044 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0327323 |
| HDLBP | high density lipoprotein binding protein | -0.0324953 |
| GOLGA4 | golgin A4 | -0.0321405 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0318296 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0316088 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0303473 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0300397 |
| AHNAK | AHNAK nucleoprotein | -0.0298062 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0296189 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0296003 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | -0.029484 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 | -0.0292942 |
| RRBP1 | ribosome binding protein 1 | -0.0292789 |
| COL5A2 | collagen, type V, alpha 2 | -0.0292217 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0289609 |
| ACTG1 | actin gamma 1 | -0.0288157 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0286165 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0284735 |
| POTEF | POTE ankyrin domain family, member F | -0.0273309 |
| LMNA | lamin A/C | -0.027054 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0266353 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0263719 |
| RPS21 | ribosomal protein S21 | -0.026021 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0259796 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0258655 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0256941 |
| SYNDIG1 | synapse differentiation inducing 1 | -0.0255786 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0255226 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0252634 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0251032 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0248974 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0247222 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0246951 |
| GNAS | GNAS complex locus | -0.024667 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0246116 |
| POU2F2 | POU class 2 homeobox 2 | -0.024375 |
| MT2A | metallothionein 2A | -0.0238825 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.0237843 |
| CCDC91 | coiled-coil domain containing 91 | -0.0229943 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0225493 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0224851 |
| MAP4 | microtubule-associated protein 4 | -0.0222653 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0222382 |
| PRRX1 | paired related homeobox 1 | -0.0222087 |
| HLA-C | major histocompatibility complex, class I, C | -0.0218466 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0213814 |
| TMEM131 | transmembrane protein 131 | -0.0213469 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0212881 |
| MTSS1 | metastasis suppressor 1 | -0.0212447 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0206443 |
| C1R | complement component 1, r subcomponent | -0.0206222 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0205723 |
| TMEM165 | transmembrane protein 165 | -0.0205095 |
| PTMA | prothymosin, alpha | -0.0203889 |
| FTL | ferritin, light polypeptide | -0.0201001 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0200922 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0197749 |
| COLEC10 | collectin sub-family member 10 (C-type lectin) | -0.0195982 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.01959 |
| EGR1 | early growth response 1 | -0.0194972 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0194152 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0193919 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0189735 |
| ANO10 | anoctamin 10 | -0.0189654 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0187443 |
| CA12 | carbonic anhydrase XII | -0.0186136 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0183977 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.018368 |
| ANKRD12 | ankyrin repeat domain 12 | -0.018228 |
| S100A9 | S100 calcium binding protein A9 | -0.0180671 |
