| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Palmatine (chloride) perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Palmatine (chloride)_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE10A | phosphodiesterase 10A | 0.143758 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0601421 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0573992 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0486397 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0460731 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0406863 |
| CNKSR3 | CNKSR family member 3 | 0.0364997 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0341927 |
| ASPH | aspartate beta-hydroxylase | 0.0330327 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.030505 |
| TOX | thymocyte selection-associated high mobility group box | 0.0254415 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0250455 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.0248381 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0239538 |
| PLSCR1 | phospholipid scramblase 1 | 0.0234752 |
| MTAP | methylthioadenosine phosphorylase | 0.023193 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0225238 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.022351 |
| IRS2 | insulin receptor substrate 2 | 0.02109 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0205712 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0205559 |
| NCKAP5 | NCK-associated protein 5 | 0.0205065 |
| EHBP1 | EH domain binding protein 1 | 0.0200237 |
| UBE2QL1 | ubiquitin-conjugating enzyme E2Q family-like 1 | 0.0199271 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0198982 |
| NLGN1 | neuroligin 1 | 0.019511 |
| EGFR | epidermal growth factor receptor | 0.0194441 |
| TRPA1 | transient receptor potential cation channel, subfamily A, member 1 | 0.0192915 |
| GPATCH2L | G patch domain containing 2-like | 0.0190262 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0188077 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0182015 |
| MX2 | MX dynamin-like GTPase 2 | 0.0179973 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.017819 |
| RALYL | RALY RNA binding protein-like | 0.017665 |
| SVIL | supervillin | 0.0175515 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0171568 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0167249 |
| SIK2 | salt-inducible kinase 2 | 0.0167194 |
| VCL | vinculin | 0.0164414 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | 0.0163678 |
| FAT1 | FAT atypical cadherin 1 | 0.0163428 |
| SCFD2 | sec1 family domain containing 2 | 0.0162342 |
| CNTNAP5 | contactin associated protein-like 5 | 0.0157793 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0155783 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0151496 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0151403 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.015116 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0149473 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 | 0.0147083 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0144244 |
| CARD18 | caspase recruitment domain family, member 18 | 0.0144193 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.014353 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.014301 |
| HDAC4 | histone deacetylase 4 | 0.014185 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | 0.0140447 |
| AP3B2 | adaptor-related protein complex 3, beta 2 subunit | 0.01397 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0139153 |
| SP100 | SP100 nuclear antigen | 0.0138733 |
| TUFT1 | tuftelin 1 | 0.0135801 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0133285 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0132574 |
| LSAMP | limbic system-associated membrane protein | 0.0130995 |
| RNF213 | ring finger protein 213 | 0.0129678 |
| GDAP1 | ganglioside induced differentiation associated protein 1 | 0.0127995 |
| THADA | thyroid adenoma associated | 0.0127467 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.01271 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0126704 |
| BPTF | bromodomain PHD finger transcription factor | 0.0125317 |
| WWOX | WW domain containing oxidoreductase | 0.0124959 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0121205 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0120241 |
| ARRB1 | arrestin, beta 1 | 0.0119531 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0119416 |
| TOX3 | TOX high mobility group box family member 3 | 0.0118986 |
| SGMS2 | sphingomyelin synthase 2 | 0.0116754 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0116264 |
| SNX5 | sorting nexin 5 | 0.0116054 |
| AOPEP | aminopeptidase O (putative) | 0.0115144 |
| GLIS3 | GLIS family zinc finger 3 | 0.0114755 |
| COMMD10 | COMM domain containing 10 | 0.0114613 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0114278 |
| PHF14 | PHD finger protein 14 | 0.011403 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0113583 |
| INTS7 | integrator complex subunit 7 | 0.0113124 |
| RRM2 | ribonucleotide reductase M2 | 0.01125 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | 0.0111931 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | 0.0111063 |
| ATM | ATM serine/threonine kinase | 0.0110883 |
| JMJD1C | jumonji domain containing 1C | 0.0110832 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0110586 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0110243 |
| PPIP5K2 | diphosphoinositol pentakisphosphate kinase 2 | 0.0109682 |
| PMP22 | peripheral myelin protein 22 | 0.0109536 |
| EFNA5 | ephrin-A5 | 0.0109498 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0109423 |
| MTIF2 | mitochondrial translational initiation factor 2 | 0.010933 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.0108851 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0108805 |
| MEF2D | myocyte enhancer factor 2D | 0.0108759 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0108395 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.116496 |
| PTMA | prothymosin, alpha | -0.10738 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0970689 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0856972 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.080889 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0784759 |
| DTNA | dystrobrevin, alpha | -0.0720968 |
| VGF | VGF nerve growth factor inducible | -0.0672783 |
| MAP1B | microtubule-associated protein 1B | -0.0643539 |
| GPC6 | glypican 6 | -0.0618578 |
| RPS6 | ribosomal protein S6 | -0.0602089 |
| ENO1 | enolase 1, (alpha) | -0.0553295 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.052401 |
| CALCA | calcitonin-related polypeptide alpha | -0.0456363 |
| TMSB4X | thymosin beta 4, X-linked | -0.0449042 |
| EGR1 | early growth response 1 | -0.0437053 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0425308 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0425255 |
| PEG10 | paternally expressed 10 | -0.0424127 |
| PKM | pyruvate kinase, muscle | -0.0423891 |
| MATR3 | matrin 3 | -0.0417433 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0405926 |
| FAM13A | family with sequence similarity 13, member A | -0.0395517 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0387663 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0385181 |
| FTL | ferritin, light polypeptide | -0.0384979 |
| GNAS | GNAS complex locus | -0.0383043 |
| TPD52 | tumor protein D52 | -0.0376324 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0367348 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.0364499 |
| WDR45B | WD repeat domain 45B | -0.035176 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.0351672 |
| SCG2 | secretogranin II | -0.0349496 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0344395 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0337396 |
| NFIA | nuclear factor I/A | -0.0336931 |
| RPS21 | ribosomal protein S21 | -0.0334959 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0333075 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | -0.0328784 |
| RPS3 | ribosomal protein S3 | -0.0327656 |
| NCAM1 | neural cell adhesion molecule 1 | -0.0327219 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0326382 |
| RPL8 | ribosomal protein L8 | -0.0323155 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0322799 |
| PGK1 | phosphoglycerate kinase 1 | -0.0314327 |
| FOXC1 | forkhead box C1 | -0.0313937 |
| RPL23 | ribosomal protein L23 | -0.0313102 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0310618 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0309388 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.030825 |
| RPS25 | ribosomal protein S25 | -0.0307994 |
| RPS27 | ribosomal protein S27 | -0.0304817 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0303237 |
| RORA | RAR-related orphan receptor A | -0.0302814 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0298502 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0298454 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0296316 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0290682 |
| RPL19 | ribosomal protein L19 | -0.0286831 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0285506 |
| RPL26 | ribosomal protein L26 | -0.0282724 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0275323 |
| RPL34 | ribosomal protein L34 | -0.0272576 |
| JAM3 | junctional adhesion molecule 3 | -0.0271658 |
| RPL4 | ribosomal protein L4 | -0.0269658 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0265795 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.026251 |
| SEPTIN7 | septin 7 | -0.0260596 |
| SYT1 | synaptotagmin I | -0.0257013 |
| KIF26B | kinesin family member 26B | -0.0256583 |
| ONECUT2 | one cut homeobox 2 | -0.0256234 |
| PCBP3 | poly(rC) binding protein 3 | -0.0256037 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0255896 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0253359 |
| CA8 | carbonic anhydrase VIII | -0.0252961 |
| RPS16 | ribosomal protein S16 | -0.0251782 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0251454 |
| RPL37A | ribosomal protein L37a | -0.0250723 |
| RPS19 | ribosomal protein S19 | -0.0249282 |
| MSI2 | musashi RNA-binding protein 2 | -0.0248211 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0247912 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0246309 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0244806 |
| S100A9 | S100 calcium binding protein A9 | -0.024403 |
| PTK2 | protein tyrosine kinase 2 | -0.0241358 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0240295 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0240186 |
| GOLGA4 | golgin A4 | -0.0239765 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0237818 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0236051 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0235682 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0234998 |
| ZNF292 | zinc finger protein 292 | -0.0234108 |
| MORF4L2 | mortality factor 4 like 2 | -0.0231841 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0231375 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | -0.0230698 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.022985 |
| UBB | ubiquitin B | -0.0228886 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0228344 |
| PPME1 | protein phosphatase methylesterase 1 | -0.0227834 |
