| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Palmatine (chloride) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Palmatine (chloride)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FMN1 | formin 1 | 0.166526 |
| FNDC3B | fibronectin type III domain containing 3B | 0.127699 |
| DST | dystonin | 0.0800663 |
| RUNX1 | runt-related transcription factor 1 | 0.076998 |
| FN1 | fibronectin 1 | 0.0757015 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0623046 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0600303 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0600013 |
| NRG3 | neuregulin 3 | 0.0553543 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0541502 |
| FRMD5 | FERM domain containing 5 | 0.0538418 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0527435 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0527231 |
| CCND1 | cyclin D1 | 0.0525452 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0473751 |
| FLNA | filamin A, alpha | 0.0467596 |
| ANXA2 | annexin A2 | 0.0441742 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0438683 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0436531 |
| AMOTL1 | angiomotin like 1 | 0.0433593 |
| INPP5F | inositol polyphosphate-5-phosphatase F | 0.0421758 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0418475 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0417518 |
| HDAC9 | histone deacetylase 9 | 0.041584 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0407137 |
| ENO1 | enolase 1, (alpha) | 0.0381663 |
| NAV2 | neuron navigator 2 | 0.0375854 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0374512 |
| LDHA | lactate dehydrogenase A | 0.0371694 |
| RNF213 | ring finger protein 213 | 0.0370275 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0356665 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0346157 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0341361 |
| ETV6 | ets variant 6 | 0.0337708 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.033734 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0335766 |
| SQSTM1 | sequestosome 1 | 0.0329507 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0325314 |
| PTK2 | protein tyrosine kinase 2 | 0.0321868 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0321545 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0320764 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0320068 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0313062 |
| SVIL | supervillin | 0.0311338 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0307842 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0305335 |
| CD44 | CD44 molecule (Indian blood group) | 0.0297617 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0294749 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0294498 |
| ATXN1 | ataxin 1 | 0.0293516 |
| OGA | O-GlcNAcase | 0.0293512 |
| CDK6 | cyclin-dependent kinase 6 | 0.0292505 |
| RIGI | RNA sensor RIG-I | 0.0280452 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0280158 |
| PLSCR1 | phospholipid scramblase 1 | 0.0279555 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0273659 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0273465 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0271606 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0269003 |
| SMAD3 | SMAD family member 3 | 0.0268514 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0265965 |
| RAD51B | RAD51 paralog B | 0.0265509 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0264963 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0262913 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0262698 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0257205 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0256 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | 0.0253581 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0244808 |
| FGGY | FGGY carbohydrate kinase domain containing | 0.0242569 |
| OPHN1 | oligophrenin 1 | 0.0238265 |
| NRP2 | neuropilin 2 | 0.0235568 |
| CYTH3 | cytohesin 3 | 0.0234784 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0234614 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0233469 |
| ASPH | aspartate beta-hydroxylase | 0.023338 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0231963 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0230819 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0229976 |
| MSN | moesin | 0.0229573 |
| ADAR | adenosine deaminase, RNA-specific | 0.0228482 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0222925 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0222831 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0222762 |
| FRMD4A | FERM domain containing 4A | 0.0221723 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.0221368 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0220068 |
| FLNB | filamin B, beta | 0.0219578 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0219552 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0217591 |
| ERBIN | erbb2 interacting protein | 0.0214385 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.021345 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0212946 |
| AFDN | afadin, adherens junction formation factor | 0.0211768 |
| IFI44L | interferon-induced protein 44-like | 0.021169 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0211209 |
| FBXO32 | F-box protein 32 | 0.0211102 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0211064 |
| CTSB | cathepsin B | 0.0210455 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0209107 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LSAMP | limbic system-associated membrane protein | -0.106068 |
| RPS6 | ribosomal protein S6 | -0.0908537 |
| VIM | vimentin | -0.0809714 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0799551 |
| TMSB10 | thymosin beta 10 | -0.0762451 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0675443 |
| RPS3 | ribosomal protein S3 | -0.0644586 |
| RPL23 | ribosomal protein L23 | -0.0607885 |
| RPL35A | ribosomal protein L35a | -0.0597859 |
| FTL | ferritin, light polypeptide | -0.0590237 |
| PTMA | prothymosin, alpha | -0.0589289 |
| NLGN1 | neuroligin 1 | -0.0580924 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0531969 |
| RPLP1 | ribosomal protein, large, P1 | -0.0500432 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.048693 |
| RPL34 | ribosomal protein L34 | -0.0471408 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0436836 |
| RPS21 | ribosomal protein S21 | -0.0431787 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0422 |
| GOLGA4 | golgin A4 | -0.0387787 |
| MT2A | metallothionein 2A | -0.0365995 |
| RPS23 | ribosomal protein S23 | -0.0359959 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.035861 |
| RPL11 | ribosomal protein L11 | -0.0354065 |
| S100A9 | S100 calcium binding protein A9 | -0.0328103 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0326676 |
| RPL31 | ribosomal protein L31 | -0.0309846 |
| RPS13 | ribosomal protein S13 | -0.0308382 |
| RPL12 | ribosomal protein L12 | -0.0306143 |
| RPL36A | ribosomal protein L36a | -0.0297449 |
| RPS19 | ribosomal protein S19 | -0.0295424 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0295097 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0284683 |
| RPL37A | ribosomal protein L37a | -0.0283384 |
| RPS14 | ribosomal protein S14 | -0.0281756 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0281167 |
| RPLP2 | ribosomal protein, large, P2 | -0.0277525 |
| RPL32 | ribosomal protein L32 | -0.0276644 |
| RPS24 | ribosomal protein S24 | -0.0276387 |
| RPL37 | ribosomal protein L37 | -0.0271294 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.0267829 |
| RPS8 | ribosomal protein S8 | -0.0262709 |
| RPS4X | ribosomal protein S4, X-linked | -0.0262567 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0261336 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0259061 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0258266 |
| RPS12 | ribosomal protein S12 | -0.0252333 |
| RPL36 | ribosomal protein L36 | -0.024939 |
| SLC39A11 | solute carrier family 39, member 11 | -0.024244 |
| RPL38 | ribosomal protein L38 | -0.0239187 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0238855 |
| SNU13 | small nuclear ribonucleoprotein 13 | -0.0233643 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0230598 |
| CTSD | cathepsin D | -0.0228699 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0228622 |
| RPS11 | ribosomal protein S11 | -0.0223784 |
| PRAME | preferentially expressed antigen in melanoma | -0.022204 |
| RPS16 | ribosomal protein S16 | -0.0207591 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0207569 |
| RPL8 | ribosomal protein L8 | -0.0206861 |
| ATF4 | activating transcription factor 4 | -0.0203286 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0202966 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0200481 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0198813 |
| RPS29 | ribosomal protein S29 | -0.0196404 |
| RPS27A | ribosomal protein S27a | -0.0194954 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0194633 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0194321 |
| MT1X | metallothionein 1X | -0.0193803 |
| MSI2 | musashi RNA-binding protein 2 | -0.0191992 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.019048 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0187356 |
| RPL19 | ribosomal protein L19 | -0.0185902 |
| RPS15 | ribosomal protein S15 | -0.0183765 |
| RPL5 | ribosomal protein L5 | -0.0183235 |
| RPL26 | ribosomal protein L26 | -0.0182664 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0181619 |
| ASTN2 | astrotactin 2 | -0.0179673 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0176937 |
| MMP12 | matrix metallopeptidase 12 | -0.0173832 |
| RPS17 | ribosomal protein S17 | -0.0172874 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0172473 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0169975 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0166494 |
| RPS27 | ribosomal protein S27 | -0.0165579 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.016479 |
| RHOA | ras homolog family member A | -0.0164782 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0162766 |
| MFSD12 | major facilitator superfamily domain containing 12 | -0.0162091 |
| RPL28 | ribosomal protein L28 | -0.0161609 |
| RPS25 | ribosomal protein S25 | -0.0160702 |
| ENTHD1 | ENTH domain containing 1 | -0.0158812 |
| RPL35 | ribosomal protein L35 | -0.0158668 |
| RPS5 | ribosomal protein S5 | -0.0157489 |
| LAMTOR5 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 | -0.0152582 |
| RPL27A | ribosomal protein L27a | -0.0150967 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0148875 |
| HMGA1 | high mobility group AT-hook 1 | -0.0146527 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.0144645 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0143172 |
