| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Palmatine (chloride) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Palmatine (chloride)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0906171 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0672412 |
| BICC1 | BicC family RNA binding protein 1 | 0.0634957 |
| SMAD3 | SMAD family member 3 | 0.0531111 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0516771 |
| HDAC9 | histone deacetylase 9 | 0.0468676 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.046456 |
| ANXA2 | annexin A2 | 0.0447418 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0431695 |
| EXT1 | exostosin glycosyltransferase 1 | 0.041236 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0393895 |
| SQSTM1 | sequestosome 1 | 0.0380839 |
| INTS6 | integrator complex subunit 6 | 0.0375891 |
| ATXN1 | ataxin 1 | 0.0373449 |
| RPS8 | ribosomal protein S8 | 0.0361746 |
| FN1 | fibronectin 1 | 0.0349913 |
| RPS2 | ribosomal protein S2 | 0.0338681 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0327879 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0321178 |
| VCL | vinculin | 0.0319884 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0306878 |
| FLNA | filamin A, alpha | 0.0300063 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0284442 |
| COL6A3 | collagen, type VI, alpha 3 | 0.02831 |
| AHNAK | AHNAK nucleoprotein | 0.0270234 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0253348 |
| GLIS3 | GLIS family zinc finger 3 | 0.0251139 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0249996 |
| APP | amyloid beta (A4) precursor protein | 0.0243657 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0242747 |
| CANX | calnexin | 0.0242123 |
| FAM20C | family with sequence similarity 20, member C | 0.0241466 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.024076 |
| RPS3 | ribosomal protein S3 | 0.0234037 |
| ASPH | aspartate beta-hydroxylase | 0.0229747 |
| CEP250 | centrosomal protein 250kDa | 0.0228916 |
| RPL31 | ribosomal protein L31 | 0.0221251 |
| SVIL | supervillin | 0.0220413 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0220258 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0217409 |
| RPS29 | ribosomal protein S29 | 0.0214693 |
| RPL37A | ribosomal protein L37a | 0.0211266 |
| OGA | O-GlcNAcase | 0.0208143 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0203705 |
| MLPH | melanophilin | 0.0200101 |
| TGM2 | transglutaminase 2 | 0.0199725 |
| SEPTIN9 | septin 9 | 0.019887 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0196772 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0191061 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0190554 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0189498 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0189141 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0187857 |
| RPS25 | ribosomal protein S25 | 0.0187118 |
| SMYD3 | SET and MYND domain containing 3 | 0.0184357 |
| RPL7 | ribosomal protein L7 | 0.0180061 |
| AHR | aryl hydrocarbon receptor | 0.0179468 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0176156 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0172014 |
| RPS12 | ribosomal protein S12 | 0.0170513 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0168095 |
| THBS1 | thrombospondin 1 | 0.0166671 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0163634 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0161581 |
| VMP1 | vacuole membrane protein 1 | 0.0161505 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0160723 |
| MCL1 | myeloid cell leukemia 1 | 0.0158807 |
| ZNF608 | zinc finger protein 608 | 0.0158516 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0157066 |
| SH3BP4 | SH3-domain binding protein 4 | 0.0155891 |
| MYO10 | myosin X | 0.0153052 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0152824 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0152162 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0150469 |
| RPS27 | ribosomal protein S27 | 0.0150174 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0149347 |
| RPL13A | ribosomal protein L13a | 0.0148424 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0148238 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0145807 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0145672 |
| RPLP1 | ribosomal protein, large, P1 | 0.0145455 |
| BPTF | bromodomain PHD finger transcription factor | 0.0145096 |
| CLTC | clathrin, heavy chain (Hc) | 0.0143816 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | 0.014303 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0140747 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0140024 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0139623 |
| RPS27A | ribosomal protein S27a | 0.0139536 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 | 0.0137465 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0136596 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0135617 |
| THBS2 | thrombospondin 2 | 0.0135258 |
| RPL39 | ribosomal protein L39 | 0.0134842 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0133679 |
| GOLGB1 | golgin B1 | 0.0131982 |
| PRELID2 | PRELI domain containing 2 | 0.0131882 |
| SFTPA2 | surfactant protein A2 | 0.0131649 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0131085 |
| LDHA | lactate dehydrogenase A | 0.0130886 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0130498 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.280942 |
| TMSB10 | thymosin beta 10 | -0.118763 |
| FRMD4A | FERM domain containing 4A | -0.116305 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.10793 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0980678 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0874347 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0850798 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0677617 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0675778 |
| EGR1 | early growth response 1 | -0.0666919 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0650586 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0628443 |
| IER3 | immediate early response 3 | -0.0611556 |
| PLIN2 | perilipin 2 | -0.0572245 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0517596 |
| NDRG1 | N-myc downstream regulated 1 | -0.0497077 |
| CADM1 | cell adhesion molecule 1 | -0.0494823 |
| TMSB4X | thymosin beta 4, X-linked | -0.0489256 |
| CTSD | cathepsin D | -0.04868 |
| CD44 | CD44 molecule (Indian blood group) | -0.0480875 |
| ADM | adrenomedullin | -0.0412255 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0403744 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0388423 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0383991 |
| INHBA | inhibin, beta A | -0.0375909 |
| GNAS | GNAS complex locus | -0.0362744 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0357151 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0344846 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0338107 |
| MMP12 | matrix metallopeptidase 12 | -0.0318644 |
| DIAPH2 | diaphanous-related formin 2 | -0.031311 |
| HMGA1 | high mobility group AT-hook 1 | -0.030779 |
| FTL | ferritin, light polypeptide | -0.0304041 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0279475 |
| CDH13 | cadherin 13 | -0.0278521 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0275071 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0262714 |
| RPS21 | ribosomal protein S21 | -0.0259538 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0254833 |
| ATP13A3 | ATPase type 13A3 | -0.0252751 |
| HLA-B | major histocompatibility complex, class I, B | -0.0252109 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0249743 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0248742 |
| RAI14 | retinoic acid induced 14 | -0.0247907 |
| RND3 | Rho family GTPase 3 | -0.0246751 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0246618 |
| BNC2 | basonuclin 2 | -0.0246475 |
| STC1 | stanniocalcin 1 | -0.0244916 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0242996 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0242216 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0241275 |
| MT1X | metallothionein 1X | -0.024103 |
| VEGFA | vascular endothelial growth factor A | -0.0239205 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0238038 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0237541 |
| C3 | complement component 3 | -0.0237454 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0236863 |
| CLMP | CXADR-like membrane protein | -0.0236625 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0235085 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0222581 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase | -0.0219938 |
| CBX3 | chromobox homolog 3 | -0.021971 |
| NRN1 | neuritin 1 | -0.0217503 |
| LSAMP | limbic system-associated membrane protein | -0.0215852 |
| COL1A1 | collagen, type I, alpha 1 | -0.0208044 |
| INSIG1 | insulin induced gene 1 | -0.0207983 |
| LOX | lysyl oxidase | -0.0207787 |
| SNX9 | sorting nexin 9 | -0.0207653 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0205891 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0203126 |
| CD63 | CD63 molecule | -0.0201591 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0200746 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0198434 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0198214 |
| RPS24 | ribosomal protein S24 | -0.0198041 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0198026 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.019548 |
| MIDN | midnolin | -0.019402 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0192471 |
| DEK | DEK proto-oncogene | -0.0191794 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0191496 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0191436 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0189092 |
| PFN1 | profilin 1 | -0.0187385 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0186952 |
| ASTN2 | astrotactin 2 | -0.0185588 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0184958 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0184604 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0183725 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0182955 |
| PDE10A | phosphodiesterase 10A | -0.0182586 |
| IL6 | interleukin 6 | -0.0182039 |
| PHF21A | PHD finger protein 21A | -0.0179048 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0179046 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0178566 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0177665 |
| JUN | jun proto-oncogene | -0.0172453 |
| MAP1B | microtubule-associated protein 1B | -0.017086 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0169392 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0168935 |
