| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Palmatine (chloride) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Palmatine (chloride)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.120006 |
| FN1 | fibronectin 1 | 0.116693 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.106903 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0998641 |
| GLIS3 | GLIS family zinc finger 3 | 0.0917459 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0896693 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0879732 |
| ANXA2 | annexin A2 | 0.0856646 |
| MAP1B | microtubule-associated protein 1B | 0.0818486 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0805519 |
| HMGA2 | high mobility group AT-hook 2 | 0.0790435 |
| PRELID2 | PRELI domain containing 2 | 0.0762126 |
| FLNA | filamin A, alpha | 0.0718372 |
| ENO1 | enolase 1, (alpha) | 0.0707218 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0701767 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0693155 |
| CD44 | CD44 molecule (Indian blood group) | 0.0691247 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0665927 |
| LDHA | lactate dehydrogenase A | 0.0655964 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0582616 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.058215 |
| TPM4 | tropomyosin 4 | 0.0555571 |
| PRSS23 | protease, serine, 23 | 0.0549948 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.054471 |
| SMYD3 | SET and MYND domain containing 3 | 0.0536617 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0533774 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0527774 |
| CALU | calumenin | 0.0512125 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0510953 |
| DPYD | dihydropyrimidine dehydrogenase | 0.050259 |
| PTK2 | protein tyrosine kinase 2 | 0.0500786 |
| ECE1 | endothelin converting enzyme 1 | 0.0499621 |
| SEPTIN7 | septin 7 | 0.0494303 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0489294 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0470627 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0452592 |
| ATXN1 | ataxin 1 | 0.0451572 |
| ERBIN | erbb2 interacting protein | 0.0449056 |
| EXOC4 | exocyst complex component 4 | 0.0443901 |
| USP34 | ubiquitin specific peptidase 34 | 0.0429052 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0424865 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0420951 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0419671 |
| AHNAK | AHNAK nucleoprotein | 0.0416732 |
| PRKCA | protein kinase C, alpha | 0.0414024 |
| RUNX1 | runt-related transcription factor 1 | 0.0408315 |
| ASPH | aspartate beta-hydroxylase | 0.0407785 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0404726 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0402655 |
| CALD1 | caldesmon 1 | 0.0396327 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0388868 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0386184 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0382352 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.037771 |
| EXOC6B | exocyst complex component 6B | 0.0377505 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0377422 |
| PDGFC | platelet derived growth factor C | 0.0376787 |
| RASAL2 | RAS protein activator like 2 | 0.0366934 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.035822 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0355498 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.035509 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0355014 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.03523 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0349714 |
| FAM20C | family with sequence similarity 20, member C | 0.0347629 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0344331 |
| ALK | anaplastic lymphoma receptor tyrosine kinase | 0.0339879 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0326467 |
| CANX | calnexin | 0.0324323 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0323549 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0323197 |
| HPCAL1 | hippocalcin-like 1 | 0.0320699 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0319551 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.031821 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | 0.0315764 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0315384 |
| CCDC14 | coiled-coil domain containing 14 | 0.0314827 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0313737 |
| RAD51B | RAD51 paralog B | 0.0304779 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0304045 |
| KIF2A | kinesin heavy chain member 2A | 0.0301222 |
| NAV1 | neuron navigator 1 | 0.0298473 |
| FAT1 | FAT atypical cadherin 1 | 0.0295007 |
| ITGAV | integrin, alpha V | 0.0289177 |
| KIF5B | kinesin family member 5B | 0.0287614 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0286603 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0285201 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0281052 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0280271 |
| NRXN3 | neurexin 3 | 0.0280217 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.027771 |
| TAOK1 | TAO kinase 1 | 0.0277429 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0275646 |
| SYNPO | synaptopodin | 0.0275617 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0274002 |
| AHR | aryl hydrocarbon receptor | 0.0273969 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0273021 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0272805 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0272096 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0271787 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.132428 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.121353 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.104472 |
| HLA-B | major histocompatibility complex, class I, B | -0.0998453 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0809524 |
| NDRG1 | N-myc downstream regulated 1 | -0.0713849 |
| PTMA | prothymosin, alpha | -0.0524373 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0495185 |
| GOLGA4 | golgin A4 | -0.0460149 |
| RPL23 | ribosomal protein L23 | -0.0422773 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0411987 |
| MT2A | metallothionein 2A | -0.0404671 |
| B2M | beta-2-microglobulin | -0.0395289 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0394281 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0391561 |
| SDC4 | syndecan 4 | -0.039075 |
| S100A10 | S100 calcium binding protein A10 | -0.0389385 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0386945 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0384776 |
| IL6 | interleukin 6 | -0.0373379 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0365263 |
| H3-3B | H3.3 histone B | -0.0361412 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0358635 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0352485 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0346853 |
| COG5 | component of oligomeric golgi complex 5 | -0.0342262 |
| RPL37 | ribosomal protein L37 | -0.0341985 |
| CCNI | cyclin I | -0.0339553 |
| S100A6 | S100 calcium binding protein A6 | -0.033932 |
| RPL12 | ribosomal protein L12 | -0.0337376 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0335803 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0331694 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0312337 |
| RPL28 | ribosomal protein L28 | -0.0310413 |
| PTGES2 | prostaglandin E synthase 2 | -0.030804 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.030316 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0295078 |
| RPS13 | ribosomal protein S13 | -0.0289173 |
| CD63 | CD63 molecule | -0.0288337 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0279129 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0276095 |
| RPS6 | ribosomal protein S6 | -0.0270404 |
| RPS11 | ribosomal protein S11 | -0.0270104 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0269773 |
| RPS23 | ribosomal protein S23 | -0.0268764 |
| MORF4L2 | mortality factor 4 like 2 | -0.0268452 |
| RPS5 | ribosomal protein S5 | -0.0268451 |
| ADM | adrenomedullin | -0.0264106 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0263433 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0261403 |
| RPL35A | ribosomal protein L35a | -0.0258018 |
| HBP1 | HMG-box transcription factor 1 | -0.0253372 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0249803 |
| TMEM165 | transmembrane protein 165 | -0.0249734 |
| RPS24 | ribosomal protein S24 | -0.0249733 |
| CFDP1 | craniofacial development protein 1 | -0.0247628 |
| RPL32 | ribosomal protein L32 | -0.0247126 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0246984 |
| GOLGB1 | golgin B1 | -0.0245173 |
| MED13L | mediator complex subunit 13-like | -0.0242733 |
| RPLP1 | ribosomal protein, large, P1 | -0.0240415 |
| FRMD6 | FERM domain containing 6 | -0.0240029 |
| RPL26 | ribosomal protein L26 | -0.0233875 |
| ELP2 | elongator acetyltransferase complex subunit 2 | -0.0233228 |
| LMNA | lamin A/C | -0.0232735 |
| COL3A1 | collagen, type III, alpha 1 | -0.0231075 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.023033 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0229246 |
| NOP58 | NOP58 ribonucleoprotein | -0.0227737 |
| RPS8 | ribosomal protein S8 | -0.0226118 |
| ARRDC3 | arrestin domain containing 3 | -0.0226018 |
| HLA-A | major histocompatibility complex, class I, A | -0.0225964 |
| RPL31 | ribosomal protein L31 | -0.0224789 |
| TOMM7 | translocase of outer mitochondrial membrane 7 homolog (yeast) | -0.0223332 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0221886 |
| KAZN | kazrin, periplakin interacting protein | -0.0221726 |
| RPL38 | ribosomal protein L38 | -0.0220758 |
| COPA | coatomer protein complex, subunit alpha | -0.0219723 |
| RPS16 | ribosomal protein S16 | -0.0219017 |
| PFN1 | profilin 1 | -0.0216659 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0215304 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0214082 |
| PCOLCE | procollagen C-endopeptidase enhancer | -0.0213496 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0213203 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0212257 |
| HM13 | histocompatibility (minor) 13 | -0.0211236 |
| S100A9 | S100 calcium binding protein A9 | -0.0210109 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0208873 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0208129 |
| RPS12 | ribosomal protein S12 | -0.0208066 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0207023 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0206486 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0205318 |
| C1R | complement component 1, r subcomponent | -0.0205142 |
| NAV2 | neuron navigator 2 | -0.0203966 |
| MT1X | metallothionein 1X | -0.0202382 |
| RPS17 | ribosomal protein S17 | -0.0200906 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0200601 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0199364 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.019835 |
