Palmatine (chloride)_SW 900 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Palmatine (chloride) perturbation in SW 900 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Palmatine (chloride)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
VCL vinculin 0.1172
EXT1 exostosin glycosyltransferase 1 0.117116
ASPH aspartate beta-hydroxylase 0.11369
NTN4 netrin 4 0.0805462
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0793013
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.0695122
GLIS3 GLIS family zinc finger 3 0.0621072
NPAS2 neuronal PAS domain protein 2 0.0554366
NRG1 neuregulin 1 0.0550897
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.0529324
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.0489433
TMEM156 transmembrane protein 156 0.0471052
PALLD palladin, cytoskeletal associated protein 0.0459701
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.0450163
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.0449042
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.044522
SEPTIN9 septin 9 0.043807
TOP1 topoisomerase (DNA) I 0.0430133
NRP1 neuropilin 1 0.0428367
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 0.0392817
RIGI RNA sensor RIG-I 0.0392308
INTS6 integrator complex subunit 6 0.0392146
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 0.0391258
STAT1 signal transducer and activator of transcription 1, 91kDa 0.0376227
PDLIM5 PDZ and LIM domain 5 0.0366881
TTC28 tetratricopeptide repeat domain 28 0.0360056
AEBP2 AE binding protein 2 0.0352584
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.0351349
RAB10 RAB10, member RAS oncogene family 0.0342227
NRIP1 nuclear receptor interacting protein 1 0.0342127
GPATCH2L G patch domain containing 2-like 0.0337862
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.0330587
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.0330039
LTBP1 latent transforming growth factor beta binding protein 1 0.0327991
RNF213 ring finger protein 213 0.0325098
BICD1 bicaudal D homolog 1 (Drosophila) 0.0324266
SVIL supervillin 0.0321678
FOXP1 forkhead box P1 0.0320803
SMAD3 SMAD family member 3 0.0318418
RAB31 RAB31, member RAS oncogene family 0.0313452
MX2 MX dynamin-like GTPase 2 0.031111
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0308066
FHL2 four and a half LIM domains 2 0.0304961
OSMR oncostatin M receptor 0.0301278
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0301228
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.0301082
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.0297566
SPRED2 sprouty-related, EVH1 domain containing 2 0.0296841
WWTR1 WW domain containing transcription regulator 1 0.0293729
ANKRD28 ankyrin repeat domain 28 0.0287454
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.028432
TNNC1 troponin C type 1 (slow) 0.0280537
FNDC3B fibronectin type III domain containing 3B 0.0274238
NCOA7 nuclear receptor coactivator 7 0.0266015
SHB Src homology 2 domain containing adaptor protein B 0.0265616
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 0.0265188
PCDH7 protocadherin 7 0.0263278
EPC2 enhancer of polycomb homolog 2 (Drosophila) 0.0261516
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 0.0255189
RSAD2 radical S-adenosyl methionine domain containing 2 0.0255068
KSR1 kinase suppressor of ras 1 0.0254475
VEGFC vascular endothelial growth factor C 0.0254413
NALF1 NALCN channel auxiliary factor 1 0.0254318
VCAN versican 0.0244876
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0242913
ZNFX1 zinc finger, NFX1-type containing 1 0.0239478
TGFB2 transforming growth factor, beta 2 0.0238586
FLNA filamin A, alpha 0.0238302
LPP LIM domain containing preferred translocation partner in lipoma 0.0231863
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.0231293
SDC2 syndecan 2 0.0229158
NXN nucleoredoxin 0.0228799
PHC2 polyhomeotic homolog 2 (Drosophila) 0.0227801
FNDC3A fibronectin type III domain containing 3A 0.0227332
RBMS1 RNA binding motif, single stranded interacting protein 1 0.022636
IFI6 interferon, alpha-inducible protein 6 0.0225641
MYO10 myosin X 0.0223968
VPS13B vacuolar protein sorting 13 homolog B (yeast) 0.0222027
SMYD3 SET and MYND domain containing 3 0.0220527
MLPH melanophilin 0.0219066
VMP1 vacuole membrane protein 1 0.0218185
ATXN1 ataxin 1 0.0216711
RDH10 retinol dehydrogenase 10 (all-trans) 0.0216313
PTK2 protein tyrosine kinase 2 0.0216175
RABGAP1L RAB GTPase activating protein 1-like 0.0216164
DUSP16 dual specificity phosphatase 16 0.021608
HOMER1 homer scaffolding protein 1 0.0214148
OASL 2'-5'-oligoadenylate synthetase-like 0.0212494
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0211889
JMJD1C jumonji domain containing 1C 0.0210245
CPEB4 cytoplasmic polyadenylation element binding protein 4 0.0208936
CLIP2 CAP-GLY domain containing linker protein 2 0.0207879
MX1 MX dynamin-like GTPase 1 0.0206893
IL6ST interleukin 6 signal transducer 0.0206604
EGFR epidermal growth factor receptor 0.0206308
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.0205064
PDE4D phosphodiesterase 4D, cAMP-specific 0.020424
IFI44 interferon-induced protein 44 0.0204079
NBEA neurobeachin 0.0203776
CD44 CD44 molecule (Indian blood group) 0.0203032

decreased expression

Symbol Name Standardized Value
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.210182
NDRG1 N-myc downstream regulated 1 -0.134139
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.117484
PTMA prothymosin, alpha -0.109089
P4HB prolyl 4-hydroxylase, beta polypeptide -0.091017
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.076809
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.0762632
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0751477
TMSB4X thymosin beta 4, X-linked -0.0713831
RPS6 ribosomal protein S6 -0.0710107
TMSB10 thymosin beta 10 -0.0698154
MRPS6 mitochondrial ribosomal protein S6 -0.067863
STC2 stanniocalcin 2 -0.0658346
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0579504
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 -0.0578303
FTL ferritin, light polypeptide -0.0563003
CXCL8 chemokine (C-X-C motif) ligand 8 -0.0562778
HILPDA hypoxia inducible lipid droplet-associated -0.0493137
NAMPT nicotinamide phosphoribosyltransferase -0.0479923
CD109 CD109 molecule -0.0475729
GOLGA4 golgin A4 -0.0475322
MT2A metallothionein 2A -0.0473941
FTH1 ferritin, heavy polypeptide 1 -0.0460903
CANX calnexin -0.0459322
FAM13A family with sequence similarity 13, member A -0.0447093
PKM pyruvate kinase, muscle -0.0434437
PRRC2C proline-rich coiled-coil 2C -0.0394869
AKAP12 A kinase (PRKA) anchor protein 12 -0.037941
PLIN2 perilipin 2 -0.0378268
VEGFA vascular endothelial growth factor A -0.0372784
PDIA3 protein disulfide isomerase family A, member 3 -0.0363246
LMNA lamin A/C -0.0361627
NAP1L1 nucleosome assembly protein 1-like 1 -0.0344166
TRIO trio Rho guanine nucleotide exchange factor -0.0341816
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.0338083
ESYT2 extended synaptotagmin-like protein 2 -0.0337926
ZFP36L1 ZFP36 ring finger protein-like 1 -0.0331954
RPL35A ribosomal protein L35a -0.0330677
CALR calreticulin -0.0330488
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.0323408
KDM3A lysine (K)-specific demethylase 3A -0.0319706
ITGA1 integrin, alpha 1 -0.0319568
IGFBP3 insulin-like growth factor binding protein 3 -0.0318245
TMEM165 transmembrane protein 165 -0.0314548
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 -0.0311005
TXNIP thioredoxin interacting protein -0.0308786
S100A6 S100 calcium binding protein A6 -0.030612
HLA-B major histocompatibility complex, class I, B -0.0304657
RPLP1 ribosomal protein, large, P1 -0.0302088
SUCO SUN domain containing ossification factor -0.0298862
CADM1 cell adhesion molecule 1 -0.0285164
RPS27 ribosomal protein S27 -0.0278686
ZNF292 zinc finger protein 292 -0.0274206
WDR45B WD repeat domain 45B -0.0272246
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0269598
TPT1 tumor protein, translationally-controlled 1 -0.0269511
HELZ helicase with zinc finger -0.0266822
RPS21 ribosomal protein S21 -0.0263033
VIM vimentin -0.0262565
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.0259471
RPL34 ribosomal protein L34 -0.0250361
RSF1 remodeling and spacing factor 1 -0.0250329
ACBD3 acyl-CoA binding domain containing 3 -0.0247596
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0245014
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 -0.0238174
IRF2BP2 interferon regulatory factor 2 binding protein 2 -0.0235216
RAI14 retinoic acid induced 14 -0.0234153
MARK3 MAP/microtubule affinity-regulating kinase 3 -0.0234066
RPL31 ribosomal protein L31 -0.0233603
PGK1 phosphoglycerate kinase 1 -0.023284
RPS19 ribosomal protein S19 -0.0228527
RPL23 ribosomal protein L23 -0.0227956
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -0.0224809
NPEPPS aminopeptidase puromycin sensitive -0.0220747
IRAK3 interleukin-1 receptor-associated kinase 3 -0.0220293
S100A9 S100 calcium binding protein A9 -0.0218688
RIOK3 RIO kinase 3 -0.021703
SEC23A Sec23 homolog A (S. cerevisiae) -0.0216771
RPL8 ribosomal protein L8 -0.0216654
ERRFI1 ERBB receptor feedback inhibitor 1 -0.0215731
SQSTM1 sequestosome 1 -0.0214695
ANKRD11 ankyrin repeat domain 11 -0.0213037
PDIA6 protein disulfide isomerase family A, member 6 -0.0212802
MXI1 MAX interactor 1, dimerization protein -0.0212005
RPL26 ribosomal protein L26 -0.0211662
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0211326
YME1L1 YME1-like 1 ATPase -0.0209447
LOC112694756 uncharaterized LOC112694756 -0.0209279
H1-0 H1.0 linker histone -0.0209216
TFPI2 tissue factor pathway inhibitor 2 -0.0208969
UGCG UDP-glucose ceramide glucosyltransferase -0.0208946
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -0.0208803
ZCCHC7 zinc finger, CCHC domain containing 7 -0.0208114
RPS3 ribosomal protein S3 -0.0207692
RPL19 ribosomal protein L19 -0.0205937
RPL11 ribosomal protein L11 -0.0205689
UBA6 ubiquitin-like modifier activating enzyme 6 -0.0205249
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.0202582
RAB6A RAB6A, member RAS oncogene family -0.0201486
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -0.0199589