| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Palmatine (chloride) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Palmatine (chloride)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.194049 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.132052 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.126327 |
| INTS6 | integrator complex subunit 6 | 0.121202 |
| VCL | vinculin | 0.113472 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.111871 |
| ENO1 | enolase 1, (alpha) | 0.0792885 |
| ANXA2 | annexin A2 | 0.0788978 |
| DSPP | dentin sialophosphoprotein | 0.0737536 |
| WWOX | WW domain containing oxidoreductase | 0.0702691 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0649108 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0606403 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0589486 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0585849 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0585468 |
| BCL2L1 | BCL2-like 1 | 0.0565864 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0562302 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0552788 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0551091 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0545241 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0529991 |
| FAT1 | FAT atypical cadherin 1 | 0.0524229 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0523389 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0517963 |
| EZR | ezrin | 0.0502344 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.049408 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.048855 |
| RPS2 | ribosomal protein S2 | 0.0483868 |
| GLI3 | GLI family zinc finger 3 | 0.0483157 |
| SEPTIN9 | septin 9 | 0.0479313 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0477928 |
| LMO7 | LIM domain 7 | 0.0475965 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0471193 |
| PCBP2 | poly(rC) binding protein 2 | 0.0465523 |
| SYT1 | synaptotagmin I | 0.0462031 |
| YAP1 | Yes-associated protein 1 | 0.0458238 |
| RAD51B | RAD51 paralog B | 0.0456124 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0452022 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0438653 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0438088 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0437828 |
| VMP1 | vacuole membrane protein 1 | 0.0437605 |
| TJP1 | tight junction protein 1 | 0.0437364 |
| ACTN1 | actinin, alpha 1 | 0.0435128 |
| ACTN4 | actinin, alpha 4 | 0.043231 |
| TNS3 | tensin 3 | 0.0427937 |
| SMAD3 | SMAD family member 3 | 0.0426513 |
| CENPF | centromere protein F, 350/400kDa | 0.0421804 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0418338 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0414086 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.040637 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0404964 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0404216 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0397979 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0396785 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0391837 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0385932 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0376797 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0372562 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0371166 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0371146 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0365094 |
| FLNA | filamin A, alpha | 0.0360642 |
| ECT2 | epithelial cell transforming 2 | 0.0359816 |
| YBX1 | Y box binding protein 1 | 0.0359472 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0346014 |
| SMYD3 | SET and MYND domain containing 3 | 0.0339997 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0337972 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0333683 |
| MKI67 | marker of proliferation Ki-67 | 0.0328994 |
| NEBL | nebulette | 0.0326198 |
| SYK | spleen tyrosine kinase | 0.0323921 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | 0.032269 |
| UBAP2 | ubiquitin associated protein 2 | 0.0321908 |
| BMP5 | bone morphogenetic protein 5 | 0.0320132 |
| MSI2 | musashi RNA-binding protein 2 | 0.0319891 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0318235 |
| EGFR | epidermal growth factor receptor | 0.0316338 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0315476 |
| RRM2 | ribonucleotide reductase M2 | 0.0313201 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0311568 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0311207 |
| AFAP1L2 | actin filament associated protein 1-like 2 | 0.0310284 |
| STK24 | serine/threonine kinase 24 | 0.0309271 |
| LDHA | lactate dehydrogenase A | 0.0303672 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0302897 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0301948 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0301249 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0299836 |
| AATF | apoptosis antagonizing transcription factor | 0.0299764 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0298571 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0297099 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0296927 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0296356 |
| GPHN | gephyrin | 0.0295202 |
| PRELID2 | PRELI domain containing 2 | 0.0291192 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 0.0286642 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0286581 |
| MYO10 | myosin X | 0.0286035 |
| TPI1 | triosephosphate isomerase 1 | 0.0282686 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.215312 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.172753 |
| TMSB10 | thymosin beta 10 | -0.154242 |
| RPS6 | ribosomal protein S6 | -0.132962 |
| RPL35A | ribosomal protein L35a | -0.108435 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0767507 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0738693 |
| TMSB4X | thymosin beta 4, X-linked | -0.0717199 |
| CDH13 | cadherin 13 | -0.0661922 |
| RPS19 | ribosomal protein S19 | -0.0652188 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0628213 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0614622 |
| ITGB4 | integrin, beta 4 | -0.0596702 |
| CDK6 | cyclin-dependent kinase 6 | -0.0563209 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.054895 |
| NDRG1 | N-myc downstream regulated 1 | -0.0542179 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0522518 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0504493 |
| HMGA1 | high mobility group AT-hook 1 | -0.04718 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0450772 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0444032 |
| RPL36A | ribosomal protein L36a | -0.0443278 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0435076 |
| NAV2 | neuron navigator 2 | -0.0431818 |
| RPS24 | ribosomal protein S24 | -0.04075 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0402983 |
| PTMA | prothymosin, alpha | -0.0393525 |
| CBX3 | chromobox homolog 3 | -0.0393082 |
| ZNF292 | zinc finger protein 292 | -0.0379623 |
| PERP | PERP, TP53 apoptosis effector | -0.0377922 |
| FRMD5 | FERM domain containing 5 | -0.0374762 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.0374637 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0373238 |
| VIM | vimentin | -0.0368588 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0367359 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0354595 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0353046 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0346335 |
| JMJD1C | jumonji domain containing 1C | -0.0345761 |
| GLG1 | golgi glycoprotein 1 | -0.0339511 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0332403 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0326998 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.032495 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0324463 |
| RPL23 | ribosomal protein L23 | -0.0320193 |
| KRT8 | keratin 8, type II | -0.0318362 |
| GNAS | GNAS complex locus | -0.0317475 |
| RPL34 | ribosomal protein L34 | -0.0313392 |
| MT1X | metallothionein 1X | -0.0309496 |
| S100A4 | S100 calcium binding protein A4 | -0.0305119 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0293338 |
| PFN1 | profilin 1 | -0.0292352 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0291266 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0290324 |
| FTL | ferritin, light polypeptide | -0.0288295 |
| CCND1 | cyclin D1 | -0.0288187 |
| MYOF | myoferlin | -0.0287847 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0281785 |
| ACTG1 | actin gamma 1 | -0.027896 |
| RASA3 | RAS p21 protein activator 3 | -0.0278451 |
| GOLGA4 | golgin A4 | -0.0277705 |
| THOC2 | THO complex 2 | -0.0277529 |
| RPS23 | ribosomal protein S23 | -0.0277239 |
| MATR3 | matrin 3 | -0.0274204 |
| IER3 | immediate early response 3 | -0.0272845 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.027127 |
| RBM25 | RNA binding motif protein 25 | -0.026746 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0261872 |
| RPL32 | ribosomal protein L32 | -0.0260876 |
| CEP95 | centrosomal protein 95kDa | -0.0260633 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0260075 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0257317 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0256663 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0255944 |
| MORF4L2 | mortality factor 4 like 2 | -0.0255059 |
| KIZ | kizuna centrosomal protein | -0.0253788 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0253508 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0251684 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0251406 |
| RPS14 | ribosomal protein S14 | -0.0249286 |
| RPLP1 | ribosomal protein, large, P1 | -0.0248144 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0245438 |
| IGF2 | insulin-like growth factor 2 | -0.0245135 |
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa | -0.0244877 |
| RPL4 | ribosomal protein L4 | -0.0244537 |
| HMGB1 | high mobility group box 1 | -0.0244511 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0243429 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0241812 |
| EPB41 | erythrocyte membrane protein band 4.1 | -0.0236685 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0235038 |
| RPS21 | ribosomal protein S21 | -0.0233458 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0228631 |
| SPNS2 | spinster homolog 2 (Drosophila) | -0.022842 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0228138 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0228041 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0226413 |
| RPL37 | ribosomal protein L37 | -0.0225814 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0224531 |
| RLF | rearranged L-myc fusion | -0.0222303 |
| S100A6 | S100 calcium binding protein A6 | -0.0217674 |
