| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Palmatine (chloride) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Palmatine (chloride)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NALF1 | NALCN channel auxiliary factor 1 | 0.166729 |
| FN1 | fibronectin 1 | 0.159858 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.118646 |
| MYO10 | myosin X | 0.116098 |
| B2M | beta-2-microglobulin | 0.0940787 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0939552 |
| HMGA2 | high mobility group AT-hook 2 | 0.090848 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0881573 |
| INTS6 | integrator complex subunit 6 | 0.0867441 |
| VCL | vinculin | 0.0838394 |
| HLA-B | major histocompatibility complex, class I, B | 0.0796302 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0774545 |
| GLIS3 | GLIS family zinc finger 3 | 0.0771286 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0701633 |
| NAV1 | neuron navigator 1 | 0.0681337 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0663923 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0584761 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0578128 |
| MED13L | mediator complex subunit 13-like | 0.0551209 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0544462 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0523013 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0518668 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.050735 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0496738 |
| MCL1 | myeloid cell leukemia 1 | 0.0491017 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0477692 |
| MT2A | metallothionein 2A | 0.0473628 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0467606 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0465404 |
| FBN1 | fibrillin 1 | 0.0464043 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0461056 |
| CLIC4 | chloride intracellular channel 4 | 0.0458792 |
| CDH13 | cadherin 13 | 0.0446859 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.042981 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0427837 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0399587 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0399394 |
| ADM | adrenomedullin | 0.0399057 |
| WLS | wntless Wnt ligand secretion mediator | 0.0398472 |
| POTEF | POTE ankyrin domain family, member F | 0.0395266 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.039249 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0391871 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0382584 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0382361 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0378072 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.03744 |
| ACTN1 | actinin, alpha 1 | 0.0373044 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0370038 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0369887 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0369077 |
| DGKI | diacylglycerol kinase, iota | 0.0362904 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0352648 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0350511 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0350047 |
| LYST | lysosomal trafficking regulator | 0.0347142 |
| PTK2 | protein tyrosine kinase 2 | 0.0342546 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0339307 |
| CLMP | CXADR-like membrane protein | 0.0336312 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0332968 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0331463 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0330969 |
| CUX1 | cut-like homeobox 1 | 0.0325381 |
| ASPH | aspartate beta-hydroxylase | 0.0322764 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.032245 |
| AEBP2 | AE binding protein 2 | 0.0319555 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0318609 |
| HLA-A | major histocompatibility complex, class I, A | 0.0316868 |
| NABP1 | nucleic acid binding protein 1 | 0.0316331 |
| RAB31 | RAB31, member RAS oncogene family | 0.0315966 |
| ACTG1 | actin gamma 1 | 0.0315157 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0312738 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0312537 |
| KLF12 | Kruppel-like factor 12 | 0.030909 |
| TPM4 | tropomyosin 4 | 0.030852 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0307472 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0306444 |
| NOTCH2 | notch 2 | 0.0301142 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0299824 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0296335 |
| PALLD | palladin, cytoskeletal associated protein | 0.0295374 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0292858 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0291935 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0291127 |
| SIK3 | SIK family kinase 3 | 0.0289888 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0289435 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0288919 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0281057 |
| KIAA1549L | KIAA1549-like | 0.0277428 |
| FRMD4A | FERM domain containing 4A | 0.0277152 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0276088 |
| RPS12 | ribosomal protein S12 | 0.0275997 |
| MYO1D | myosin ID | 0.0275975 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0275831 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0274156 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0274028 |
| MSN | moesin | 0.0271007 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0270878 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0268672 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0267227 |
| MYO1E | myosin IE | 0.0267156 |
| Symbol | Name | Standardized Value |
|---|---|---|
| INHBA | inhibin, beta A | -0.139697 |
| MMP1 | matrix metallopeptidase 1 | -0.124145 |
| NDRG1 | N-myc downstream regulated 1 | -0.0928826 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0857226 |
| VIM | vimentin | -0.0757543 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0752836 |
| ATP13A3 | ATPase type 13A3 | -0.066303 |
| FAM13A | family with sequence similarity 13, member A | -0.0636867 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0628913 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0624158 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0531494 |
| TMSB10 | thymosin beta 10 | -0.0524478 |
| OSMR | oncostatin M receptor | -0.0511272 |
| PLPP3 | phospholipid phosphatase 3 | -0.0431038 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0400598 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0374828 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0371972 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0368316 |
| NGLY1 | N-glycanase 1 | -0.0365567 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0355506 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0347827 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0344194 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0342853 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0338027 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0336059 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0322198 |
| PGK1 | phosphoglycerate kinase 1 | -0.0307426 |
| LOXL2 | lysyl oxidase-like 2 | -0.027527 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0267863 |
| USP3 | ubiquitin specific peptidase 3 | -0.0262817 |
| ZNF292 | zinc finger protein 292 | -0.0256601 |
| XPO1 | exportin 1 | -0.0256168 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0256067 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0254723 |
| PAMR1 | peptidase domain containing associated with muscle regeneration 1 | -0.0247033 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.024422 |
| MSI2 | musashi RNA-binding protein 2 | -0.0241769 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0235554 |
| TBC1D23 | TBC1 domain family, member 23 | -0.0235268 |
| PTMA | prothymosin, alpha | -0.0235111 |
| MMP12 | matrix metallopeptidase 12 | -0.0233755 |
| H1-0 | H1.0 linker histone | -0.0232723 |
| CDC27 | cell division cycle 27 | -0.0226732 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0224095 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0220776 |
| RRBP1 | ribosome binding protein 1 | -0.0219698 |
| SRP54 | signal recognition particle 54kDa | -0.0218084 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.021483 |
| GOLGA4 | golgin A4 | -0.0213522 |
| MTSS1 | metastasis suppressor 1 | -0.0210887 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0210267 |
| CEP95 | centrosomal protein 95kDa | -0.0207523 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0206856 |
| DUSP10 | dual specificity phosphatase 10 | -0.0202148 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | -0.019824 |
| SYAP1 | synapse associated protein 1 | -0.0195499 |
| RNF145 | ring finger protein 145 | -0.019421 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0194022 |
| CDK17 | cyclin-dependent kinase 17 | -0.0191567 |
| RAB8B | RAB8B, member RAS oncogene family | -0.0189855 |
| INSIG1 | insulin induced gene 1 | -0.0189654 |
| TNPO1 | transportin 1 | -0.0188614 |
| CENPF | centromere protein F, 350/400kDa | -0.0181855 |
| CDK19 | cyclin-dependent kinase 19 | -0.0178252 |
| RPL4 | ribosomal protein L4 | -0.0177291 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0174652 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0173022 |
| SUCO | SUN domain containing ossification factor | -0.0171487 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0168996 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0168386 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0167624 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0167157 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.016517 |
| TRPC4 | transient receptor potential cation channel, subfamily C, member 4 | -0.0164232 |
| RPL35A | ribosomal protein L35a | -0.0163843 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0163043 |
| APAF1 | apoptotic peptidase activating factor 1 | -0.0161582 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0160428 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0160308 |
| ADAMTS4 | ADAM metallopeptidase with thrombospondin type 1 motif, 4 | -0.015856 |
| HAS2 | hyaluronan synthase 2 | -0.0157128 |
| RARS1 | arginyl-tRNA synthetase 1 | -0.0157057 |
| THRAP3 | thyroid hormone receptor associated protein 3 | -0.0156891 |
| NFIL3 | nuclear factor, interleukin 3 regulated | -0.0154752 |
| TMSB4X | thymosin beta 4, X-linked | -0.0154111 |
| HM13 | histocompatibility (minor) 13 | -0.0153352 |
| YME1L1 | YME1-like 1 ATPase | -0.0151734 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.015051 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0150107 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0149964 |
| RPS24 | ribosomal protein S24 | -0.0147839 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0147645 |
| PTEN | phosphatase and tensin homolog | -0.0147435 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0147333 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0146098 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0145544 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.014547 |
| TXNRD1 | thioredoxin reductase 1 | -0.0143787 |
| ELP2 | elongator acetyltransferase complex subunit 2 | -0.0143237 |
| FBN2 | fibrillin 2 | -0.0142755 |
