Pancreatic Intraepithelial Neoplasia Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C1301034
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Genes

187 genes associated with the disease Pancreatic Intraepithelial Neoplasia in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ADAM17 ADAM metallopeptidase domain 17
ADM adrenomedullin
AGR2 anterior gradient 2
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALOX5 arachidonate 5-lipoxygenase
ALPI alkaline phosphatase, intestinal
ALPP alkaline phosphatase, placental
ANXA10 annexin A10
ANXA2 annexin A2
ARG1 arginase 1
ATF6 activating transcription factor 6
ATM ATM serine/threonine kinase
BCL2 B-cell CLL/lymphoma 2
BGLAP bone gamma-carboxyglutamate (gla) protein
BHLHA15 basic helix-loop-helix family, member a15
BIRC3 baculoviral IAP repeat containing 3
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA2 breast cancer 2, early onset
C17ORF97 chromosome 17 open reading frame 97
CA9 carbonic anhydrase IX
CADM1 cell adhesion molecule 1
CADM4 cell adhesion molecule 4
CCK cholecystokinin
CCKBR cholecystokinin B receptor
CCND1 cyclin D1
CCND3 cyclin D3
CD44 CD44 molecule (Indian blood group)
CD47 CD47 molecule
CDH15 cadherin 15, type 1, M-cadherin (myotubule)
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDX2 caudal type homeobox 2
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEMIP cell migration inducing protein, hyaluronan binding
CFLAR CASP8 and FADD-like apoptosis regulator
CHEK2 checkpoint kinase 2
CISH cytokine inducible SH2-containing protein
CLDN18 claudin 18
COASY CoA synthase
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNND1 catenin (cadherin-associated protein), delta 1
CTSE cathepsin E
CUZD1 CUB and zona pellucida-like domains 1
CX3CL1 chemokine (C-X3-C motif) ligand 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR4 chemokine (C-X-C motif) receptor 4
DUSP6 dual specificity phosphatase 6
EGFR epidermal growth factor receptor
EPAS1 endothelial PAS domain protein 1
EPHA2 EPH receptor A2
ERBB2 erb-b2 receptor tyrosine kinase 2
FASN fatty acid synthase
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGF19 fibroblast growth factor 19
FGFBP1 fibroblast growth factor binding protein 1
FGFR4 fibroblast growth factor receptor 4
FSCN1 fascin actin-bundling protein 1
FXYD3 FXYD domain containing ion transport regulator 3
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GATA6 GATA binding protein 6
GCG glucagon
GLI1 GLI family zinc finger 1
GLP1R glucagon-like peptide 1 receptor
GSK3B glycogen synthase kinase 3 beta
HES1 hes family bHLH transcription factor 1
HHLA2 HERV-H LTR-associating 2
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMGA1 high mobility group AT-hook 1
HOXB2 homeobox B2
HOXB6 homeobox B6
HRAS Harvey rat sarcoma viral oncogene homolog
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
IAPP islet amyloid polypeptide
IER3 immediate early response 3
IFNG interferon, gamma
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IL13 interleukin 13
IL17A interleukin 17A
IL1A interleukin 1, alpha
IL2RG interleukin 2 receptor, gamma
IL6 interleukin 6
IL6ST interleukin 6 signal transducer
ILK integrin-linked kinase
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
INSIG2 insulin induced gene 2
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
KCNK1 potassium channel, two pore domain subfamily K, member 1
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KLF4 Kruppel-like factor 4 (gut)
KLF5 Kruppel-like factor 5 (intestinal)
KLK10 kallikrein-related peptidase 10
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT19 keratin 19, type I
KRT20 keratin 20, type I
KSR1 kinase suppressor of ras 1
LCN2 lipocalin 2
LMO2 LIM domain only 2 (rhombotin-like 1)
LMO4 LIM domain only 4
MAGT1 magnesium transporter 1
MCAM melanoma cell adhesion molecule
MEIS1 Meis homeobox 1
MKI67 marker of proliferation Ki-67
MMRN1 multimerin 1
MRC1 mannose receptor, C type 1
MSI2 musashi RNA-binding protein 2
MST1 macrophage stimulating 1
MST1R macrophage stimulating 1 receptor
MTAP methylthioadenosine phosphorylase
MUC1 mucin 1, cell surface associated
MUC13 mucin 13, cell surface associated
MUC17 mucin 17, cell surface associated
MUC3A mucin 3A, cell surface associated
MUC3B mucin 3B, cell surface associated
MUC4 mucin 4, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC6 mucin 6, oligomeric mucus/gel-forming
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCOA3 nuclear receptor coactivator 3
NDRG2 NDRG family member 2
NES nestin
NFE2L2 nuclear factor, erythroid 2-like 2
NOTCH1 notch 1
NOTCH2 notch 2
NPY neuropeptide Y
NQO1 NAD(P)H dehydrogenase, quinone 1
NSD1 nuclear receptor binding SET domain protein 1
ONECUT1 one cut homeobox 1
PCLAF PCNA clamp associated factor
PDHX pyruvate dehydrogenase complex, component X
PDX1 pancreatic and duodenal homeobox 1
PEAK1 pseudopodium-enriched atypical kinase 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PENK proenkephalin
PHGDH phosphoglycerate dehydrogenase
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
PRDM14 PR domain containing 14
PRSS1 protease, serine, 1 (trypsin 1)
PTF1A pancreas specific transcription factor, 1a
PTGES prostaglandin E synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
REG1A regenerating islet-derived 1 alpha
REG1B regenerating islet-derived 1 beta
S100PBP S100P binding protein
SCT secretin
SETD2 SET domain containing 2
SIRT1 sirtuin 1
SLC12A9 solute carrier family 12, member 9
SMAD4 SMAD family member 4
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SNAI1 snail family zinc finger 1
SNAI2 snail family zinc finger 2
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
SOX2 SRY (sex determining region Y)-box 2
SOX9 SRY (sex determining region Y)-box 9
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPINK1 serine peptidase inhibitor, Kazal type 1
SPPL3 signal peptide peptidase like 3
SQLE squalene epoxidase
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STK4 serine/threonine kinase 4
TFF1 trefoil factor 1
TGFA transforming growth factor, alpha
TLR2 toll-like receptor 2
TLR9 toll-like receptor 9
TNC tenascin C
TP53 tumor protein p53
TRIM29 tripartite motif containing 29
UCN urocortin
UMPS uridine monophosphate synthetase
WNK2 WNK lysine deficient protein kinase 2
XBP1 X-box binding protein 1
YAP1 Yes-associated protein 1
YBX1 Y box binding protein 1
ZEB1 zinc finger E-box binding homeobox 1