Pancreatic adenocarcinoma_PAAD_TCGA-IB-7888-01A-11R-2156-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Pancreatic adenocarcinoma_PAAD (The Cancer Genome Atlas)
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405 genes with high or low expression in Pancreatic adenocarcinoma_PAAD_TCGA-IB-7888-01A-11R-2156-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
A2M alpha-2-macroglobulin
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11
ABI3BP ABI family, member 3 (NESH) binding protein
ACE angiotensin I converting enzyme
ACER2 alkaline ceramidase 2
ACTN3 actinin, alpha 3 (gene/pseudogene)
ADAM23 ADAM metallopeptidase domain 23
ADAM29 ADAM metallopeptidase domain 29
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ADAR adenosine deaminase, RNA-specific
ADGRD1 adhesion G protein-coupled receptor D1
ADGRE1 adhesion G protein-coupled receptor E1
AKR1B15 aldo-keto reductase family 1, member B15
ALDH9A1 aldehyde dehydrogenase 9 family, member A1
ALLC allantoicase
AMACR alpha-methylacyl-CoA racemase
AMPD1 adenosine monophosphate deaminase 1
ANGPT1 angiopoietin 1
ANGPT4 angiopoietin 4
ANGPTL5 angiopoietin-like 5
ANO2 anoctamin 2, calcium activated chloride channel
AP5M1 adaptor-related protein complex 5, mu 1 subunit
APOD apolipoprotein D
ARG1 arginase 1
ARNT aryl hydrocarbon receptor nuclear translocator
ART4 ADP-ribosyltransferase 4 (Dombrock blood group)
ASPA aspartoacylase
ATL1 atlastin GTPase 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
BHLHE22 basic helix-loop-helix family, member e22
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BST1 bone marrow stromal cell antigen 1
C10ORF131 chromosome 10 open reading frame 131
C12ORF49 chromosome 12 open reading frame 49
C12ORF77 chromosome 12 open reading frame 77
C17ORF102 chromosome 17 open reading frame 102
C1R complement component 1, r subcomponent
C22ORF34 chromosome 22 open reading frame 34
C6ORF222 chromosome 6 open reading frame 222
C7 complement component 7
CA2 carbonic anhydrase II
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CALR3 calreticulin 3
CAMK1G calcium/calmodulin-dependent protein kinase IG
CASS4 Cas scaffolding protein family member 4
CCDC109B coiled-coil domain containing 109B
CCDC25 coiled-coil domain containing 25
CCDC47 coiled-coil domain containing 47
CCDC80 coiled-coil domain containing 80
CCL11 chemokine (C-C motif) ligand 11
CCL19 chemokine (C-C motif) ligand 19
CCR1 chemokine (C-C motif) receptor 1
CCR2 chemokine (C-C motif) receptor 2
CD302 CD302 molecule
CD5 CD5 molecule
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CEP95 centrosomal protein 95kDa
CFH complement factor H
CHD8 chromodomain helicase DNA binding protein 8
CHN2 chimerin 2
CLDN11 claudin 11
CMKLR1 chemerin chemokine-like receptor 1
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CNRIP1 cannabinoid receptor interacting protein 1
COL14A1 collagen, type XIV, alpha 1
COL21A1 collagen, type XXI, alpha 1
COL4A4 collagen, type IV, alpha 4
COLEC11 collectin sub-family member 11
COPA coatomer protein complex, subunit alpha
COX7B2 cytochrome c oxidase subunit VIIb2
CPA6 carboxypeptidase A6
CRISPLD1 cysteine-rich secretory protein LCCL domain containing 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSMD1 CUB and Sushi multiple domains 1
CTXN3 cortexin 3
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL5 chemokine (C-X-C motif) ligand 5
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
CYB561 cytochrome b561
CYB5R4 cytochrome b5 reductase 4
CYBRD1 cytochrome b reductase 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP26C1 cytochrome P450, family 26, subfamily C, polypeptide 1
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DAD1 defender against cell death 1
DAO D-amino-acid oxidase
DCAF7 DDB1 and CUL4 associated factor 7
DCN decorin
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DEGS1 delta(4)-desaturase, sphingolipid 1
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DIO3 deiodinase, iodothyronine, type III
DIRAS2 DIRAS family, GTP-binding RAS-like 2
DISP1 dispatched homolog 1 (Drosophila)
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10
DPH3P1 diphthamide biosynthesis 3 pseudogene 1
DSC1 desmocollin 1
DUXA double homeobox A
EBF1 early B-cell factor 1
EBF2 early B-cell factor 2
EDNRB endothelin receptor type B
EEF1DP3 eukaryotic translation elongation factor 1 delta pseudogene 3
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EMB embigin
EPHA3 EPH receptor A3
EPHB1 EPH receptor B1
EPRS glutamyl-prolyl-tRNA synthetase
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ERN1 endoplasmic reticulum to nucleus signaling 1
ESR1 estrogen receptor 1
F13A1 coagulation factor XIII, A1 polypeptide
F2R coagulation factor II (thrombin) receptor
FAM131B family with sequence similarity 131, member B
FAM172A family with sequence similarity 172, member A
FAM180B family with sequence similarity 180, member B
FAM184B family with sequence similarity 184, member B
FAM69A family with sequence similarity 69, member A
FAM69C family with sequence similarity 69, member C
FAM81A family with sequence similarity 81, member A
FAT4 FAT atypical cadherin 4
FBLN5 fibulin 5
FBN1 fibrillin 1
FBP2 fructose-1,6-bisphosphatase 2
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FER1L6 fer-1-like family member 6
FKBP14 FK506 binding protein 14, 22 kDa
FKBP7 FK506 binding protein 7
FMO3 flavin containing monooxygenase 3
FOLR3 folate receptor 3 (gamma)
FPR1 formyl peptide receptor 1
FTSJ3 FtsJ homolog 3 (E. coli)
FXYD1 FXYD domain containing ion transport regulator 1
GAB4 GRB2-associated binding protein family, member 4
GABRD gamma-aminobutyric acid (GABA) A receptor, delta
GAS7 growth arrest-specific 7
GGTA1P glycoprotein, alpha-galactosyltransferase 1 pseudogene
GHSR growth hormone secretagogue receptor
GIMAP6 GTPase, IMAP family member 6
GLP2R glucagon-like peptide 2 receptor
GP5 glycoprotein V (platelet)
GPC3 glypican 3
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble)
GPX8 glutathione peroxidase 8 (putative)
GRM7 glutamate receptor, metabotropic 7
GSTM2P1 glutathione S-transferase mu 2 (muscle) pseudogene 1
GSTM5 glutathione S-transferase mu 5
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HCRTR2 hypocretin (orexin) receptor 2
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIPK2 homeodomain interacting protein kinase 2
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HORMAD2 HORMA domain containing 2
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
ICAM2 intercellular adhesion molecule 2
IFI16 interferon, gamma-inducible protein 16
IGFBP7 insulin-like growth factor binding protein 7
IL17A interleukin 17A
IL18R1 interleukin 18 receptor 1
IL33 interleukin 33
IL6R interleukin 6 receptor
IL6ST interleukin 6 signal transducer
ILF2 interleukin enhancer binding factor 2
INGX inhibitor of growth family, X-linked, pseudogene
INMT indolethylamine N-methyltransferase
INTS2 integrator complex subunit 2
IRAK3 interleukin-1 receptor-associated kinase 3
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JCHAIN joining chain of multimeric IgA and IgM
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4
KCNK2 potassium channel, two pore domain subfamily K, member 2
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KLHL33 kelch-like family member 33
KRT2 keratin 2, type II
KRTAP10-2 keratin associated protein 10-2
KRTAP4-8 keratin associated protein 4-8
L1TD1 LINE-1 type transposase domain containing 1
LAMA2 laminin, alpha 2
LEAP2 liver expressed antimicrobial peptide 2
LGALS14 lectin, galactoside-binding, soluble, 14
LHFP lipoma HMGIC fusion partner
LIM2 lens intrinsic membrane protein 2, 19kDa
LINC00028 long intergenic non-protein coding RNA 28
LINC00111 long intergenic non-protein coding RNA 111
LINC00521 long intergenic non-protein coding RNA 521
LRRC18 leucine rich repeat containing 18
LRRC4C leucine rich repeat containing 4C
LTBP2 latent transforming growth factor beta binding protein 2
MAP1A microtubule-associated protein 1A
MAP1LC3C microtubule-associated protein 1 light chain 3 gamma
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAP9 microtubule-associated protein 9
MC4R melanocortin 4 receptor
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MED13 mediator complex subunit 13
MEF2C myocyte enhancer factor 2C
MEOX2 mesenchyme homeobox 2
METTL2A methyltransferase like 2A
MFSD4 major facilitator superfamily domain containing 4
MGP matrix Gla protein
MMP1 matrix metallopeptidase 1
MMP21 matrix metallopeptidase 21
MNDA myeloid cell nuclear differentiation antigen
MNS1 meiosis-specific nuclear structural 1
MOXD1 monooxygenase, DBH-like 1
MRGPRD MAS-related GPR, member D
MRO maestro
MUSK muscle, skeletal, receptor tyrosine kinase
MYL10 myosin, light chain 10, regulatory
NALCN sodium leak channel, non selective
NAV3 neuron navigator 3
NBPF22P neuroblastoma breakpoint family, member 22, pseudogene
NDRG2 NDRG family member 2
NFIB nuclear factor I/B
NGFR nerve growth factor receptor
NHSL2 NHS-like 2
NKAPL NFKB activating protein-like
NLGN3 neuroligin 3
NLRP14 NLR family, pyrin domain containing 14
NOV nephroblastoma overexpressed
NPHP3-AS1 NPHP3 antisense RNA 1
NRP1 neuropilin 1
NT5C1B 5'-nucleotidase, cytosolic IB
NT5DC2 5'-nucleotidase domain containing 2
NTSR2 neurotensin receptor 2
NXPE3 neurexophilin and PC-esterase domain family, member 3
OCM2 oncomodulin 2
OGN osteoglycin
OLFML1 olfactomedin-like 1
OMD osteomodulin
OPCML opioid binding protein/cell adhesion molecule-like
OR10V1 olfactory receptor, family 10, subfamily V, member 1
OR4N2 olfactory receptor, family 4, subfamily N, member 2
OR52H1 olfactory receptor, family 52, subfamily H, member 1
OR52W1 olfactory receptor, family 52, subfamily W, member 1
OR5B21 olfactory receptor, family 5, subfamily B, member 21
OR6N1 olfactory receptor, family 6, subfamily N, member 1
OTOP1 otopetrin 1
OXA1L oxidase (cytochrome c) assembly 1-like
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
PALM2-AKAP2 PALM2-AKAP2 readthrough
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDHGA9 protocadherin gamma subfamily A, 9
PDE1A phosphodiesterase 1A, calmodulin-dependent
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PHACTR2 phosphatase and actin regulator 2
PID1 phosphotyrosine interaction domain containing 1
PLA2G3 phospholipase A2, group III
PLA2G4E phospholipase A2, group IVE
PLAC9 placenta-specific 9
PLB1 phospholipase B1
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
PRCP prolylcarboxypeptidase (angiotensinase C)
PRELP proline/arginine-rich end leucine-rich repeat protein
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRG4 proteoglycan 4
PRKX protein kinase, X-linked
PROS1 protein S (alpha)
PROX2 prospero homeobox 2
PRR23C proline rich 23C
PRR34 proline rich 34
PRTG protogenin
PRUNE prune exopolyphosphatase
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PTGIS prostaglandin I2 (prostacyclin) synthase
RARS2 arginyl-tRNA synthetase 2, mitochondrial
RASL11B RAS-like, family 11, member B
RBMS3 RNA binding motif, single stranded interacting protein 3
RCL1 RNA terminal phosphate cyclase-like 1
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RFPL4B ret finger protein-like 4B
RGS18 regulator of G-protein signaling 18
RLN3 relaxin 3
RNASE4 ribonuclease, RNase A family, 4
RNF148 ring finger protein 148
ROR1 receptor tyrosine kinase-like orphan receptor 1
RPL29P2 ribosomal protein L29 pseudogene 2
RPS26 ribosomal protein S26
RTP1 receptor (chemosensory) transporter protein 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SCARA5 scavenger receptor class A, member 5
SCARNA9L small Cajal body-specific RNA 9-like
SCFD2 sec1 family domain containing 2
SCGB2A1 secretoglobin, family 2A, member 1
SCN4B sodium channel, voltage gated, type IV beta subunit
SCN7A sodium channel, voltage gated, type VII alpha subunit
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SEP15 15 kDa selenoprotein
SEPT11 septin 11
SEPT4 septin 4
SEPT7 septin 7
SEPT8 septin 8
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SETBP1 SET binding protein 1
SFRP1 secreted frizzled-related protein 1
SFRP4 secreted frizzled-related protein 4
SH3BGRL SH3 domain binding glutamate-rich protein like
SHISA3 shisa family member 3
SIGLECL1 SIGLEC family like 1
SLC16A14 solute carrier family 16, member 14
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC25A51P1 solute carrier family 25, member 51 pseudogene 1
SLC30A7 solute carrier family 30 (zinc transporter), member 7
SLC38A8 solute carrier family 38, member 8
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC9A4 solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
SLFN11 schlafen family member 11
SLIT2 slit homolog 2 (Drosophila)
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
SMCO3 single-pass membrane protein with coiled-coil domains 3
SMIM21 small integral membrane protein 21
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SNORD89 small nucleolar RNA, C/D box 89
SNX27 sorting nexin family member 27
SPATA45 spermatogenesis associated 45
SPATA5 spermatogenesis associated 5
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SRPX sushi-repeat containing protein, X-linked
SSPN sarcospan
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
STEAP4 STEAP family member 4
STH saitohin
STS steroid sulfatase (microsomal), isozyme S
STX12 syntaxin 12
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae)
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYN3 synapsin III
SYS1-DBNDD2 SYS1-DBNDD2 readthrough (NMD candidate)
SYT11 synaptotagmin XI
TACO1 translational activator of mitochondrially encoded cytochrome c oxidase I
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TARSL2 threonyl-tRNA synthetase-like 2
TCF4 transcription factor 4
TEK TEK tyrosine kinase, endothelial
TEKT4 tektin 4
TENM4 teneurin transmembrane protein 4
TEX2 testis expressed 2
THBS4 thrombospondin 4
THSD4 thrombospondin, type I, domain containing 4
THSD7B thrombospondin, type I, domain containing 7B
TIMP1 TIMP metallopeptidase inhibitor 1
TLK2 tousled-like kinase 2
TLR1 toll-like receptor 1
TMC2 transmembrane channel-like 2
TMCO3 transmembrane and coiled-coil domains 3
TMEM119 transmembrane protein 119
TMEM132E transmembrane protein 132E
TMEM154 transmembrane protein 154
TMEM167A transmembrane protein 167A
TMEM98 transmembrane protein 98
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TNNC1 troponin C type 1 (slow)
TOR1AIP1 torsin A interacting protein 1
TP53TG5 TP53 target 5
TPPP2 tubulin polymerization-promoting protein family member 2
TPRXL tetra-peptide repeat homeobox-like
TPTE2P3 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 pseudogene 3
TREML4 triggering receptor expressed on myeloid cells-like 4
TREML5P triggering receptor expressed on myeloid cells-like 5, pseudogene
TRIM9 tripartite motif containing 9
TSHB thyroid stimulating hormone, beta
TTLL2 tubulin tyrosine ligase-like family member 2
TXNDC2 thioredoxin domain containing 2 (spermatozoa)
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae)
UGCG UDP-glucose ceramide glucosyltransferase
UGT3A2 UDP glycosyltransferase 3 family, polypeptide A2
USP46 ubiquitin specific peptidase 46
UST uronyl-2-sulfotransferase
VIT vitrin
VN1R2 vomeronasal 1 receptor 2
VSIG1 V-set and immunoglobulin domain containing 1
WNT2B wingless-type MMTV integration site family, member 2B
ZCCHC5 zinc finger, CCHC domain containing 5
ZNF430 zinc finger protein 430
ZNF492 zinc finger protein 492
ZNF675 zinc finger protein 675
ZNF705D zinc finger protein 705D
ZNF883 zinc finger protein 883
ZNHIT6 zinc finger, HIT-type containing 6
ZSCAN12P1 zinc finger and SCAN domain containing 12 pseudogene 1
ZSCAN5B zinc finger and SCAN domain containing 5B

low expression

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
ELMOD3 ELMO/CED-12 domain containing 3
MARK3 MAP/microtubule affinity-regulating kinase 3
NFU1 NFU1 iron-sulfur cluster scaffold
PCBP1 poly(rC) binding protein 1
TTC31 tetratricopeptide repeat domain 31