Pancreatitis Gene Set

Dataset DISEASES Experimental Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description Inflammation of the pancreas.|INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis. (Experimental Factor Ontology, EFO_0000278)
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Genes

59 genes associated with the disease Pancreatitis in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
PRSS1 protease, serine, 1 (trypsin 1) 2.039
EPHB6 EPH receptor B6 2.039
PRSS2 protease, serine, 2 (trypsin 2) 2.039
TBC1D8B TBC1 domain family, member 8B (with GRAM domain) 2.02
MORC4 MORC family CW-type zinc finger 4 2.02
NUP62CL nucleoporin 62kDa C-terminal like 2.019
RBM41 RNA binding motif protein 41 2.018
RIPPLY1 ripply transcriptional repressor 1 2.017
CLDN2 claudin 2 2.017
TRPV6 transient receptor potential cation channel, subfamily V, member 6 2.005
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.987
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16 1.987
CTRC chymotrypsin C (caldecrin) 1.981
CELA2A chymotrypsin-like elastase family, member 2A 1.981
EFHD2 EF-hand domain family, member D2 1.981
CELA2B chymotrypsin-like elastase family, member 2B 1.981
FHAD1 forkhead-associated (FHA) phosphopeptide binding domain 1 1.97
RNF128 ring finger protein 128, E3 ubiquitin protein ligase 1.962
RADX RPA1 related single stranded DNA binding protein, X-linked 1.909
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 1.473
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 1.473
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1 1.473
LRPPRC leucine-rich pentatricopeptide repeat containing 1.473
PLEKHH2 pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 1.473
AGMAT agmatine ureohydrolase (agmatinase) 1.31
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae) 1.31
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 1.302
MED8 mediator complex subunit 8 1.169
C1ORF210 chromosome 1 open reading frame 210 1.169
HYI hydroxypyruvate isomerase (putative) 1.169
EBNA1BP2 EBNA1 binding protein 2 1.169
SZT2 seizure threshold 2 homolog (mouse) 1.169
CDC20 cell division cycle 20 1.169
TMEM125 transmembrane protein 125 1.169
ELOVL1 ELOVL fatty acid elongase 1 1.169
MPL MPL proto-oncogene, thrombopoietin receptor 1.169
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 1.169
CFDP1 craniofacial development protein 1 1.127
ZFP1 ZFP1 zinc finger protein 1.127
BCAR1 breast cancer anti-estrogen resistance 1 1.127
CTRB1 chymotrypsinogen B1 1.127
CTRB2 chymotrypsinogen B2 1.127
CPA4 carboxypeptidase A4 1.071
CPA5 carboxypeptidase A5 1.071
CPA2 carboxypeptidase A2 (pancreatic) 1.071
TMEM209 transmembrane protein 209 1.071
SSMEM1 serine-rich single-pass membrane protein 1 1.071
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 1.061
RSC1A1 regulatory solute carrier protein, family 1, member 1 0.983
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 0.983
NIBAN2 niban apoptosis regulator 2 0.845
LRSAM1 leucine rich repeat and sterile alpha motif containing 1 0.845
C5ORF46 chromosome 5 open reading frame 46 0.845
SPINK1 serine peptidase inhibitor, Kazal type 1 0.845
STXBP1 syntaxin binding protein 1 0.845
JAKMIP2 janus kinase and microtubule interacting protein 2 0.845
SCGB3A2 secretoglobin, family 3A, member 2 0.845
PTRH1 peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae) 0.845
PWWP3B PWWP domain containing 3B 0.611