| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Panobinostat perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Panobinostat_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLAT | plasminogen activator, tissue | 0.13733 |
| FBN1 | fibrillin 1 | 0.0902058 |
| GLIS3 | GLIS family zinc finger 3 | 0.078127 |
| STC1 | stanniocalcin 1 | 0.0706942 |
| CD44 | CD44 molecule (Indian blood group) | 0.0696371 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0637281 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0521964 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.052159 |
| VCL | vinculin | 0.0520503 |
| COL3A1 | collagen, type III, alpha 1 | 0.0508132 |
| SMYD3 | SET and MYND domain containing 3 | 0.0474684 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0469205 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.044413 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0438714 |
| CAVIN1 | caveolae associated protein 1 | 0.0438638 |
| SDC4 | syndecan 4 | 0.0416996 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0391692 |
| CTSB | cathepsin B | 0.0376033 |
| APP | amyloid beta (A4) precursor protein | 0.036947 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0333571 |
| SFTPA2 | surfactant protein A2 | 0.0333142 |
| ZNF217 | zinc finger protein 217 | 0.0331156 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0328849 |
| OR51B5 | olfactory receptor, family 51, subfamily B, member 5 | 0.0325882 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0323333 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0321214 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.031313 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0308573 |
| MT1X | metallothionein 1X | 0.0291655 |
| PCNX2 | pecanex 2 | 0.0275782 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0273487 |
| PLEC | plectin | 0.0262317 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.026168 |
| COL1A2 | collagen, type I, alpha 2 | 0.0254777 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0253148 |
| NBEA | neurobeachin | 0.0253129 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.025261 |
| LYST | lysosomal trafficking regulator | 0.0250794 |
| NABP1 | nucleic acid binding protein 1 | 0.0249566 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0243879 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0235507 |
| ASPH | aspartate beta-hydroxylase | 0.0231664 |
| TENM1 | teneurin transmembrane protein 1 | 0.0231394 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0224836 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.021571 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.021338 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0212425 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0210727 |
| DST | dystonin | 0.0210401 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0206982 |
| ENAH | enabled homolog (Drosophila) | 0.0206655 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0206045 |
| FRMD5 | FERM domain containing 5 | 0.0199987 |
| KIFAP3 | kinesin-associated protein 3 | 0.0195908 |
| PGK1 | phosphoglycerate kinase 1 | 0.0195459 |
| EXOC6B | exocyst complex component 6B | 0.0192363 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0190803 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0189684 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0188806 |
| CNKSR3 | CNKSR family member 3 | 0.0187068 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0186555 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0186102 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0184062 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0182898 |
| R3HDM1 | R3H domain containing 1 | 0.0182577 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0177765 |
| TXNRD1 | thioredoxin reductase 1 | 0.0176204 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0174729 |
| DNMBP | dynamin binding protein | 0.0173209 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.0170216 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0165347 |
| NCAM1 | neural cell adhesion molecule 1 | 0.0164722 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.0162904 |
| VMP1 | vacuole membrane protein 1 | 0.0162819 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0161736 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.015888 |
| RAI14 | retinoic acid induced 14 | 0.0158371 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0157927 |
| ACTN4 | actinin, alpha 4 | 0.0157866 |
| CLIC4 | chloride intracellular channel 4 | 0.0156632 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0156072 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0155256 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0154932 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.0154136 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0153999 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0152573 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0152153 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0152033 |
| INTS6 | integrator complex subunit 6 | 0.015181 |
| GPC6 | glypican 6 | 0.0151273 |
| FMN2 | formin 2 | 0.0151228 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0151147 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0150971 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0149944 |
| TOR1AIP2 | torsin A interacting protein 2 | 0.0149511 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0148374 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0147222 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.0147037 |
| TMSB4X | thymosin beta 4, X-linked | 0.0145917 |
| CREB1 | cAMP responsive element binding protein 1 | 0.0145313 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.192939 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.190848 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.157814 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.156471 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.152972 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.106688 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0950212 |
| NDRG1 | N-myc downstream regulated 1 | -0.0877614 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.079202 |
| CSTB | cystatin B (stefin B) | -0.0763962 |
| MAP1B | microtubule-associated protein 1B | -0.0740687 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0716842 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0712617 |
| CDH13 | cadherin 13 | -0.0664903 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0623943 |
| MYOF | myoferlin | -0.0621345 |
| CD109 | CD109 molecule | -0.0620853 |
| CCND1 | cyclin D1 | -0.0593969 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0583554 |
| MSI2 | musashi RNA-binding protein 2 | -0.0556654 |
| SQSTM1 | sequestosome 1 | -0.0546351 |
| LOX | lysyl oxidase | -0.0533815 |
| EGFR | epidermal growth factor receptor | -0.0504882 |
| S100A6 | S100 calcium binding protein A6 | -0.0489355 |
| TPM4 | tropomyosin 4 | -0.048409 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | -0.0473441 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0469885 |
| FOSL1 | FOS-like antigen 1 | -0.0452893 |
| AHNAK | AHNAK nucleoprotein | -0.0446649 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0446541 |
| GOLGA4 | golgin A4 | -0.0429263 |
| VIM | vimentin | -0.0429182 |
| DCLK2 | doublecortin-like kinase 2 | -0.0428169 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0426649 |
| CALR | calreticulin | -0.0419496 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0395939 |
| CANX | calnexin | -0.0380428 |
| LOXL2 | lysyl oxidase-like 2 | -0.0373349 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0369588 |
| RTN4 | reticulon 4 | -0.0369169 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0366769 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0362357 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0358412 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0356389 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0342053 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0341168 |
| ZNF292 | zinc finger protein 292 | -0.0339215 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0333967 |
| RND3 | Rho family GTPase 3 | -0.0324775 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0314682 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0313167 |
| OGA | O-GlcNAcase | -0.0308321 |
| INSIG1 | insulin induced gene 1 | -0.0308274 |
| COPA | coatomer protein complex, subunit alpha | -0.0302764 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0299039 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0289756 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0286594 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0277986 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0273203 |
| ULK1 | unc-51 like autophagy activating kinase 1 | -0.0269771 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0269708 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0260909 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0259539 |
| MMP12 | matrix metallopeptidase 12 | -0.0259258 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 | -0.0258423 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0257982 |
| FNIP1 | folliculin interacting protein 1 | -0.025763 |
| HELZ | helicase with zinc finger | -0.0257447 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0256815 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0256008 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0255146 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0254685 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0253288 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0251901 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0250547 |
| S100A10 | S100 calcium binding protein A10 | -0.0250111 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 | -0.0249671 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | -0.0247218 |
| ADM | adrenomedullin | -0.0246822 |
| TAOK1 | TAO kinase 1 | -0.0245922 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0244217 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0243598 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0241693 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0240154 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0239169 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0238803 |
| STK10 | serine/threonine kinase 10 | -0.0238062 |
| PFN1 | profilin 1 | -0.0237421 |
| L1CAM | L1 cell adhesion molecule | -0.0236172 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0236166 |
| POTEF | POTE ankyrin domain family, member F | -0.0232582 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0231001 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0230844 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0230051 |
| FTL | ferritin, light polypeptide | -0.0229722 |
| CYLD | cylindromatosis (turban tumor syndrome) | -0.0229119 |
| PODXL | podocalyxin-like | -0.0226894 |
| SEPTIN7 | septin 7 | -0.0226119 |
| VEGFA | vascular endothelial growth factor A | -0.0225301 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0223466 |
