| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Panobinostat perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Panobinostat_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0285914 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.022118 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0219769 |
| EZR | ezrin | 0.0216683 |
| MGAT4C | MGAT4 family, member C | 0.0212699 |
| MYO10 | myosin X | 0.0199966 |
| TPM3 | tropomyosin 3 | 0.0192342 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0188082 |
| TGM2 | transglutaminase 2 | 0.0173173 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0171407 |
| RPL3 | ribosomal protein L3 | 0.0166954 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0147471 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0145281 |
| CCND2 | cyclin D2 | 0.0140214 |
| PEG10 | paternally expressed 10 | 0.0139934 |
| AUTS2 | autism susceptibility candidate 2 | 0.0132333 |
| SPAG9 | sperm associated antigen 9 | 0.0130268 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0127045 |
| TSPAN5 | tetraspanin 5 | 0.0124814 |
| H1-0 | H1.0 linker histone | 0.0122562 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0120541 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.011673 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0113692 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 0.0111699 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0110351 |
| PPM1L | protein phosphatase, Mg2+/Mn2+ dependent, 1L | 0.0110126 |
| NONO | non-POU domain containing, octamer-binding | 0.0109166 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0108889 |
| WWC1 | WW and C2 domain containing 1 | 0.0108758 |
| ITGA6 | integrin, alpha 6 | 0.0107402 |
| FMNL2 | formin-like 2 | 0.0107394 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0107079 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0106774 |
| CACNA1C | calcium channel, voltage-dependent, L type, alpha 1C subunit | 0.0104517 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0103957 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.010211 |
| EDA | ectodysplasin A | 0.0100454 |
| CLIC4 | chloride intracellular channel 4 | 0.009991 |
| DOCK4 | dedicator of cytokinesis 4 | 0.00996498 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.00985303 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.00985108 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | 0.0098329 |
| TMEM108 | transmembrane protein 108 | 0.00980321 |
| ANXA1 | annexin A1 | 0.00976921 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.00951851 |
| RRM2 | ribonucleotide reductase M2 | 0.00951133 |
| HLTF | helicase-like transcription factor | 0.00949333 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.00889267 |
| GOLIM4 | golgi integral membrane protein 4 | 0.00889199 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.00875242 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.00873073 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.00870525 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.00866493 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.00864263 |
| PLEC | plectin | 0.00858782 |
| KLHL29 | kelch-like family member 29 | 0.0084358 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.00839598 |
| OSBPL6 | oxysterol binding protein-like 6 | 0.00836837 |
| PLCXD2 | phosphatidylinositol-specific phospholipase C, X domain containing 2 | 0.00820169 |
| MED12L | mediator complex subunit 12-like | 0.00810147 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.00800373 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.007965 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.00786569 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.00776164 |
| KIF5C | kinesin family member 5C | 0.00766203 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 0.0076566 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.00764075 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.00759914 |
| HELZ | helicase with zinc finger | 0.00756249 |
| FLNB | filamin B, beta | 0.00754963 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.00750042 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.00748862 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.00738151 |
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.00729802 |
| KALRN | kalirin, RhoGEF kinase | 0.00725345 |
| CAVIN1 | caveolae associated protein 1 | 0.00722282 |
| JPT1 | Jupiter microtubule associated homolog 1 | 0.00719505 |
| MSN | moesin | 0.00718847 |
| AAK1 | AP2 associated kinase 1 | 0.00717278 |
| ETV5 | ets variant 5 | 0.00713743 |
| H1-4 | H1.4 linker histone, cluster member | 0.00713423 |
| LAMA1 | laminin, alpha 1 | 0.00704913 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.00698006 |
| SH3RF2 | SH3 domain containing ring finger 2 | 0.00688654 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.00684526 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.00680792 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.00680142 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.00679835 |
| CS | citrate synthase | 0.00677863 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.00676231 |
| CCDC88A | coiled-coil domain containing 88A | 0.00674952 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0067145 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.00671169 |
| TMEM131L | transmembrane 131 like | 0.00671024 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0067096 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) | 0.00667576 |
| SSH2 | slingshot protein phosphatase 2 | 0.00666133 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.00663512 |
| SFTPA2 | surfactant protein A2 | 0.00656551 |
| DLGAP2 | discs, large (Drosophila) homolog-associated protein 2 | 0.00652753 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.147707 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.147535 |
| NLGN1 | neuroligin 1 | -0.129985 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0998603 |
| MMP12 | matrix metallopeptidase 12 | -0.0898496 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.083016 |
| TMSB10 | thymosin beta 10 | -0.0659003 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0619402 |
| PCDH7 | protocadherin 7 | -0.0564032 |
| HMGA2 | high mobility group AT-hook 2 | -0.0543221 |
| YAP1 | Yes-associated protein 1 | -0.0510491 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0490781 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.046388 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0455165 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0417607 |
| PDGFC | platelet derived growth factor C | -0.0411794 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0397881 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0393049 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0389017 |
| TENM3 | teneurin transmembrane protein 3 | -0.0383157 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0368657 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0357609 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0356326 |
| USP34 | ubiquitin specific peptidase 34 | -0.0342755 |
| FTL | ferritin, light polypeptide | -0.0337292 |
| EDARADD | EDAR-associated death domain | -0.0336713 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0327331 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0311703 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0305679 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0303502 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0300057 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.029993 |
| NHSL1 | NHS-like 1 | -0.0292382 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0279081 |
| RPL35A | ribosomal protein L35a | -0.0275014 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0273245 |
| NEBL | nebulette | -0.0268372 |
| PTMA | prothymosin, alpha | -0.0267727 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0267055 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0252742 |
| BCHE | butyrylcholinesterase | -0.0252034 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.024803 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0246036 |
| RBM39 | RNA binding motif protein 39 | -0.023373 |
| CCND1 | cyclin D1 | -0.0233137 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0232609 |
| ZNF804A | zinc finger protein 804A | -0.0229862 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0226502 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0225765 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0225052 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0224542 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0224259 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0219403 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0213762 |
| RPL23 | ribosomal protein L23 | -0.0212361 |
| RPLP1 | ribosomal protein, large, P1 | -0.0209852 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0209763 |
| TMEM41B | transmembrane protein 41B | -0.020914 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0207064 |
| ERBIN | erbb2 interacting protein | -0.0205571 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0205368 |
| RPS6 | ribosomal protein S6 | -0.0203624 |
| RPS19 | ribosomal protein S19 | -0.0202054 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0201779 |
| RPS8 | ribosomal protein S8 | -0.0201148 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0195145 |
| KLF6 | Kruppel-like factor 6 | -0.0194328 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0192516 |
| JMJD1C | jumonji domain containing 1C | -0.019239 |
| TMEM123 | transmembrane protein 123 | -0.0190992 |
| SQSTM1 | sequestosome 1 | -0.0190678 |
| BPTF | bromodomain PHD finger transcription factor | -0.0186715 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0185875 |
| LMO7 | LIM domain 7 | -0.0183521 |
| GNAS | GNAS complex locus | -0.0181203 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0178649 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0177967 |
| HDAC9 | histone deacetylase 9 | -0.0171792 |
| MTAP | methylthioadenosine phosphorylase | -0.0169907 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -0.016799 |
| RPL12 | ribosomal protein L12 | -0.0167678 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0166959 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0164701 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0164373 |
| RPL34 | ribosomal protein L34 | -0.0162775 |
| PFN1 | profilin 1 | -0.0161719 |
| MKI67 | marker of proliferation Ki-67 | -0.0160087 |
| RPS12 | ribosomal protein S12 | -0.015825 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0156817 |
| HMGA1 | high mobility group AT-hook 1 | -0.0156494 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0156288 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0155073 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0154002 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.015366 |
| AREG | amphiregulin | -0.01533 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0153104 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0152112 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0150559 |
| S100A6 | S100 calcium binding protein A6 | -0.0150094 |
| RPL19 | ribosomal protein L19 | -0.0148928 |
