| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Panobinostat perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Panobinostat_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DST | dystonin | 0.0416743 |
| PCDH9 | protocadherin 9 | 0.0388392 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0318909 |
| SMYD3 | SET and MYND domain containing 3 | 0.0314094 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0306725 |
| SEPTIN9 | septin 9 | 0.0298731 |
| DPH6 | diphthamine biosynthesis 6 | 0.0288071 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0280439 |
| NCAM1 | neural cell adhesion molecule 1 | 0.0246646 |
| PPM1E | protein phosphatase, Mg2+/Mn2+ dependent, 1E | 0.0238567 |
| ASPH | aspartate beta-hydroxylase | 0.0219335 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.0213346 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0202564 |
| DTNA | dystrobrevin, alpha | 0.0200627 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | 0.0188999 |
| ATXN1 | ataxin 1 | 0.0186285 |
| DNM3 | dynamin 3 | 0.018617 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0185065 |
| PCNX2 | pecanex 2 | 0.0183466 |
| CADM2 | cell adhesion molecule 2 | 0.0182511 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0178146 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0177775 |
| PLEC | plectin | 0.0176144 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0174543 |
| NGLY1 | N-glycanase 1 | 0.01728 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 | 0.0169856 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0162479 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.016173 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0158827 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.014675 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0141414 |
| HS6ST3 | heparan sulfate 6-O-sulfotransferase 3 | 0.0141276 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0140576 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0140448 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0139156 |
| CNTN1 | contactin 1 | 0.0138821 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0136271 |
| EFNA5 | ephrin-A5 | 0.0135364 |
| TAOK3 | TAO kinase 3 | 0.0134014 |
| RPL3 | ribosomal protein L3 | 0.013166 |
| FN1 | fibronectin 1 | 0.0131333 |
| SPAG16 | sperm associated antigen 16 | 0.0131066 |
| GSE1 | Gse1 coiled-coil protein | 0.0130969 |
| GTF3C1 | general transcription factor IIIC, polypeptide 1, alpha 220kDa | 0.0129205 |
| HDAC8 | histone deacetylase 8 | 0.0129016 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0128408 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.012816 |
| GLI3 | GLI family zinc finger 3 | 0.0127907 |
| CEP112 | centrosomal protein 112kDa | 0.0127811 |
| MEGF9 | multiple EGF-like-domains 9 | 0.0126905 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0126756 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.012667 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0126319 |
| FRMD6 | FERM domain containing 6 | 0.0125802 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0125346 |
| CCDC57 | coiled-coil domain containing 57 | 0.0124253 |
| CNTN4 | contactin 4 | 0.0123496 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0122622 |
| DNMBP | dynamin binding protein | 0.0121943 |
| MFSD4B | major facilitator superfamily domain containing 4B | 0.0121151 |
| ERGIC2 | ERGIC and golgi 2 | 0.0121019 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0120216 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.011924 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0118129 |
| AFF1 | AF4/FMR2 family, member 1 | 0.011757 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0116771 |
| CNKSR3 | CNKSR family member 3 | 0.0116705 |
| HDAC4 | histone deacetylase 4 | 0.0116367 |
| NPAS3 | neuronal PAS domain protein 3 | 0.0116038 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.011404 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0113628 |
| PFKP | phosphofructokinase, platelet | 0.0113455 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0113029 |
| UBE3D | ubiquitin protein ligase E3D | 0.0112914 |
| BNIP2 | BCL2/adenovirus E1B 19kDa interacting protein 2 | 0.0112551 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.011246 |
| KLF12 | Kruppel-like factor 12 | 0.0112365 |
| EPHA3 | EPH receptor A3 | 0.0112085 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0111466 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0111295 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.0111272 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.011081 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0110769 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0110696 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0110561 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0110258 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 0.0109648 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0109136 |
| FAM219A | family with sequence similarity 219, member A | 0.0108995 |
| CENPP | centromere protein P | 0.0108951 |
| MAPRE2 | microtubule-associated protein, RP/EB family, member 2 | 0.0108636 |
| FKBP5 | FK506 binding protein 5 | 0.0106744 |
| CAB39 | calcium binding protein 39 | 0.0106276 |
| MMP12 | matrix metallopeptidase 12 | 0.0105693 |
| NDFIP2 | Nedd4 family interacting protein 2 | 0.0105345 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0105169 |
| USP32 | ubiquitin specific peptidase 32 | 0.0105092 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.010482 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0104471 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0104293 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.363614 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.285149 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.177494 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.135182 |
| PTMA | prothymosin, alpha | -0.119934 |
| VIM | vimentin | -0.117265 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0947938 |
| ACTG1 | actin gamma 1 | -0.0887739 |
| RPL23 | ribosomal protein L23 | -0.0868799 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0713983 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0711113 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.063497 |
| RPS6 | ribosomal protein S6 | -0.0614606 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0601889 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0572578 |
| HELZ | helicase with zinc finger | -0.054239 |
| RPL19 | ribosomal protein L19 | -0.0536333 |
| RPLP1 | ribosomal protein, large, P1 | -0.0520399 |
| TMSB10 | thymosin beta 10 | -0.0505812 |
| RPL34 | ribosomal protein L34 | -0.0478215 |
| RPL35A | ribosomal protein L35a | -0.0469243 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0468932 |
| FTL | ferritin, light polypeptide | -0.046131 |
| COL1A1 | collagen, type I, alpha 1 | -0.0455905 |
| FNBP1 | formin binding protein 1 | -0.0449279 |
| FMN1 | formin 1 | -0.0442327 |
| GOLGA4 | golgin A4 | -0.0432801 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0423911 |
| LSAMP | limbic system-associated membrane protein | -0.042214 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.041942 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0413004 |
| VCL | vinculin | -0.0408065 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0407669 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0404308 |
| IER3 | immediate early response 3 | -0.0395739 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0389162 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0388119 |
| S100A6 | S100 calcium binding protein A6 | -0.0386994 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0384987 |
| B2M | beta-2-microglobulin | -0.0373198 |
| GNAS | GNAS complex locus | -0.0367005 |
| EGR1 | early growth response 1 | -0.0364832 |
| SPAG9 | sperm associated antigen 9 | -0.0360033 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0355653 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0352826 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0351474 |
| BPTF | bromodomain PHD finger transcription factor | -0.0344507 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0343557 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0343261 |
| HMGB2 | high mobility group box 2 | -0.0341225 |
| MEIS2 | Meis homeobox 2 | -0.0340496 |
| RPS19 | ribosomal protein S19 | -0.0337144 |
| RPL38 | ribosomal protein L38 | -0.0333577 |
| RPL37A | ribosomal protein L37a | -0.0330852 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0324782 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0316931 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0314565 |
| WDR45B | WD repeat domain 45B | -0.0311802 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0310237 |
| H3-3B | H3.3 histone B | -0.0308784 |
| CANX | calnexin | -0.0307228 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0305903 |
| MED13 | mediator complex subunit 13 | -0.0305101 |
| COL3A1 | collagen, type III, alpha 1 | -0.0302902 |
| MYO6 | myosin VI | -0.0302366 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0302203 |
| CEP350 | centrosomal protein 350kDa | -0.0301721 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0292452 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.0290287 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0287621 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.028648 |
| AFF4 | AF4/FMR2 family, member 4 | -0.028574 |
| TLK2 | tousled-like kinase 2 | -0.0282629 |
| RPS29 | ribosomal protein S29 | -0.028245 |
| CDC27 | cell division cycle 27 | -0.0281781 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0281001 |
| PDE8A | phosphodiesterase 8A | -0.0280298 |
| TPM4 | tropomyosin 4 | -0.0276544 |
| MSI2 | musashi RNA-binding protein 2 | -0.0274083 |
| RPS27A | ribosomal protein S27a | -0.0271649 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0268604 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0266869 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0262865 |
| CCND1 | cyclin D1 | -0.0262384 |
| ERBIN | erbb2 interacting protein | -0.0260425 |
| SQSTM1 | sequestosome 1 | -0.0259396 |
| RPL36 | ribosomal protein L36 | -0.0258336 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0256045 |
| RPS14 | ribosomal protein S14 | -0.0255984 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0254636 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0252788 |
| OGA | O-GlcNAcase | -0.025043 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0249019 |
| ZNF292 | zinc finger protein 292 | -0.0247585 |
| GDF15 | growth differentiation factor 15 | -0.0247231 |
| LMNA | lamin A/C | -0.0246161 |
| RPS23 | ribosomal protein S23 | -0.0245768 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0244003 |
| CALD1 | caldesmon 1 | -0.0242433 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0242266 |
