| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Panobinostat perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Panobinostat_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0678441 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0529368 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0486558 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0385163 |
| FAT1 | FAT atypical cadherin 1 | 0.0317513 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0284463 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.027709 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0243244 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0242341 |
| CADM1 | cell adhesion molecule 1 | 0.0196496 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0181704 |
| HLF | hepatic leukemia factor | 0.0168688 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0157507 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0154368 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0147804 |
| CFB | complement factor B | 0.0143796 |
| MBNL3 | muscleblind-like splicing regulator 3 | 0.0143322 |
| CMIP | c-Maf inducing protein | 0.0135448 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0135081 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0134051 |
| CNKSR3 | CNKSR family member 3 | 0.0133348 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.013197 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0124662 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0122197 |
| TLE4 | transducin-like enhancer of split 4 | 0.0121278 |
| PERP | PERP, TP53 apoptosis effector | 0.0121206 |
| FRK | fyn-related Src family tyrosine kinase | 0.0121199 |
| ENAH | enabled homolog (Drosophila) | 0.0120041 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | 0.0119585 |
| VEGFA | vascular endothelial growth factor A | 0.0117027 |
| NFIA | nuclear factor I/A | 0.0114313 |
| RNF43 | ring finger protein 43 | 0.0113176 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0110557 |
| FOXP1 | forkhead box P1 | 0.0110509 |
| FOXN3 | forkhead box N3 | 0.0110466 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0109478 |
| EDA | ectodysplasin A | 0.0109044 |
| SELENOP | selenoprotein P | 0.0108504 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0108366 |
| SERTAD2 | SERTA domain containing 2 | 0.0106684 |
| SLC23A1 | solute carrier family 23 (ascorbic acid transporter), member 1 | 0.0105208 |
| LMO7 | LIM domain 7 | 0.0104649 |
| CCDC88A | coiled-coil domain containing 88A | 0.0104556 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0104141 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 0.010409 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0102961 |
| RPL3 | ribosomal protein L3 | 0.0100814 |
| MAP1B | microtubule-associated protein 1B | 0.00991682 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.00957822 |
| GLRX | glutaredoxin (thioltransferase) | 0.00956693 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.00956269 |
| PTEN | phosphatase and tensin homolog | 0.00936623 |
| PGK1 | phosphoglycerate kinase 1 | 0.00928799 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.00923792 |
| FOXO3 | forkhead box O3 | 0.00918293 |
| TGM2 | transglutaminase 2 | 0.00917619 |
| ZNRF3 | zinc and ring finger 3 | 0.00905188 |
| SVIL | supervillin | 0.00876863 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.00874465 |
| PDE11A | phosphodiesterase 11A | 0.00871843 |
| HSPA12A | heat shock 70kDa protein 12A | 0.0086851 |
| SMAD3 | SMAD family member 3 | 0.00868293 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.00860801 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0085782 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.00841384 |
| PFN1 | profilin 1 | 0.00840253 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.00837285 |
| ADD3 | adducin 3 (gamma) | 0.00829621 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.00829108 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.00822312 |
| PCM1 | pericentriolar material 1 | 0.00803902 |
| DSPP | dentin sialophosphoprotein | 0.00799416 |
| LCN2 | lipocalin 2 | 0.00798001 |
| TRAK1 | trafficking protein, kinesin binding 1 | 0.00796232 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.00794091 |
| STXBP4 | syntaxin binding protein 4 | 0.00792341 |
| DNMBP | dynamin binding protein | 0.00791671 |
| SH3RF2 | SH3 domain containing ring finger 2 | 0.00790435 |
| PKM | pyruvate kinase, muscle | 0.00774825 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0077003 |
| SEPTIN9 | septin 9 | 0.00769369 |
| GPHN | gephyrin | 0.00763897 |
| PKP4 | plakophilin 4 | 0.0075778 |
| C1D | C1D nuclear receptor corepressor | 0.00756826 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.00754059 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.00751275 |
| RANBP9 | RAN binding protein 9 | 0.00747402 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.00746748 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00738768 |
| KRT8 | keratin 8, type II | 0.00737091 |
| SMAD5 | SMAD family member 5 | 0.0072759 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.00727482 |
| EML6 | echinoderm microtubule associated protein like 6 | 0.00717888 |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | 0.0071258 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.00700397 |
| KAT6A | K(lysine) acetyltransferase 6A | 0.00693793 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.00693235 |
| NDRG1 | N-myc downstream regulated 1 | 0.00690213 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.00680563 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.00680285 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.140277 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.125588 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0995189 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0889699 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0775682 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.069067 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0603291 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0587624 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0536134 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0505784 |
| SQSTM1 | sequestosome 1 | -0.0500001 |
| ACTG1 | actin gamma 1 | -0.048107 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0454508 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0449862 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0370191 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0356078 |
| CP | ceruloplasmin (ferroxidase) | -0.0354711 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0350744 |
| GPC6 | glypican 6 | -0.0349998 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0344878 |
| RBM39 | RNA binding motif protein 39 | -0.0333191 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0324899 |
| MT2A | metallothionein 2A | -0.0316445 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.031014 |
| RPLP1 | ribosomal protein, large, P1 | -0.0309724 |
| RPS6 | ribosomal protein S6 | -0.0306575 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0290511 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0287852 |
| PEG10 | paternally expressed 10 | -0.0286955 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0286249 |
| RPL37A | ribosomal protein L37a | -0.0279939 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0279799 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0277352 |
| RPS8 | ribosomal protein S8 | -0.0261188 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0258752 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0251981 |
| RPL11 | ribosomal protein L11 | -0.0248853 |
| SPAG9 | sperm associated antigen 9 | -0.0246809 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0240411 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0238951 |
| PEG3 | paternally expressed 3 | -0.0232952 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0232216 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0208961 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0208894 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0206374 |
| ITGAV | integrin, alpha V | -0.0205251 |
| FTL | ferritin, light polypeptide | -0.0205033 |
| GNAS | GNAS complex locus | -0.0203623 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0196787 |
| STK17A | serine/threonine kinase 17a | -0.0195917 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0192681 |
| RPL34 | ribosomal protein L34 | -0.0192228 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0191711 |
| RPS27A | ribosomal protein S27a | -0.0191024 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0190846 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0190685 |
| AHSG | alpha-2-HS-glycoprotein | -0.0187003 |
| RPL23 | ribosomal protein L23 | -0.0186893 |
| RPS24 | ribosomal protein S24 | -0.0185911 |
| CALR | calreticulin | -0.0185094 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.01815 |
| TMEM123 | transmembrane protein 123 | -0.0180153 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0179507 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0178701 |
| RPS3 | ribosomal protein S3 | -0.0178494 |
| TF | transferrin | -0.0178218 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0175669 |
| RPL35A | ribosomal protein L35a | -0.0175612 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0174826 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.017449 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0173856 |
| ATP10A | ATPase, class V, type 10A | -0.0173129 |
| RAI14 | retinoic acid induced 14 | -0.0173044 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0170398 |
| RACK1 | receptor for activated C kinase 1 | -0.0168963 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0161143 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0160509 |
| TFRC | transferrin receptor | -0.0160349 |
| RPLP0 | ribosomal protein, large, P0 | -0.0160262 |
| GK | glycerol kinase | -0.0156384 |
| RPS12 | ribosomal protein S12 | -0.0154114 |
| A2M | alpha-2-macroglobulin | -0.0153285 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0150336 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.014977 |
| CANX | calnexin | -0.0148172 |
| SESTD1 | SEC14 and spectrin domains 1 | -0.0148104 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0146526 |
| DNAH17 | dynein, axonemal, heavy chain 17 | -0.0146466 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | -0.0143248 |
| KIDINS220 | kinase D-interacting substrate, 220kDa | -0.0142526 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.014231 |
| RPL38 | ribosomal protein L38 | -0.0140697 |
| RPL12 | ribosomal protein L12 | -0.014012 |
| CLU | clusterin | -0.0139348 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0139317 |
| ATRN | attractin | -0.013876 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0138662 |
| PDCD11 | programmed cell death 11 | -0.0138268 |
| NPR2 | natriuretic peptide receptor 2 | -0.0137982 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0134359 |
