| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Panobinostat perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Panobinostat_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0536941 |
| PLAT | plasminogen activator, tissue | 0.0522292 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0454989 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0437498 |
| CMIP | c-Maf inducing protein | 0.0370323 |
| CUL4B | cullin 4B | 0.0338866 |
| ANLN | anillin, actin binding protein | 0.0331649 |
| VCL | vinculin | 0.0296031 |
| FLNB | filamin B, beta | 0.029467 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0286726 |
| BCL2L1 | BCL2-like 1 | 0.0275838 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0248972 |
| SLC45A4 | solute carrier family 45, member 4 | 0.0242594 |
| TGM2 | transglutaminase 2 | 0.0236382 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0235672 |
| PLEC | plectin | 0.0233233 |
| COL26A1 | collagen, type XXVI, alpha 1 | 0.0228615 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0227702 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | 0.0223587 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.02234 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.0221231 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0219143 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0214796 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.0202199 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0198644 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0197548 |
| EPHA2 | EPH receptor A2 | 0.0194696 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0194343 |
| NCOA3 | nuclear receptor coactivator 3 | 0.019188 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0190673 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0188984 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0186974 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0184522 |
| ABLIM2 | actin binding LIM protein family, member 2 | 0.0184503 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | 0.018246 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0173132 |
| GATA6 | GATA binding protein 6 | 0.0170536 |
| WDR26 | WD repeat domain 26 | 0.0167686 |
| ARRDC3 | arrestin domain containing 3 | 0.0167485 |
| PHF21A | PHD finger protein 21A | 0.0166236 |
| EFHD2 | EF-hand domain family, member D2 | 0.0164723 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0163247 |
| EMP1 | epithelial membrane protein 1 | 0.0162315 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0161959 |
| TXNRD1 | thioredoxin reductase 1 | 0.0161771 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0160642 |
| ANKRD33B | ankyrin repeat domain 33B | 0.016012 |
| PTEN | phosphatase and tensin homolog | 0.015981 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0158081 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0156665 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0152916 |
| VMP1 | vacuole membrane protein 1 | 0.0152722 |
| GOLGA4 | golgin A4 | 0.0152583 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0151761 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0149788 |
| TAOK3 | TAO kinase 3 | 0.0148435 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0148356 |
| HIP1 | huntingtin interacting protein 1 | 0.0147838 |
| BZW2 | basic leucine zipper and W2 domains 2 | 0.0146746 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0144648 |
| FAM13A | family with sequence similarity 13, member A | 0.0143963 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0141608 |
| SNX29 | sorting nexin 29 | 0.014103 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0141013 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0140028 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0139455 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0137462 |
| NUP58 | nucleoporin 58 | 0.0135577 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0134895 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0134457 |
| PLAC8 | placenta-specific 8 | 0.01344 |
| ZNF217 | zinc finger protein 217 | 0.0132926 |
| COG5 | component of oligomeric golgi complex 5 | 0.0132353 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0130489 |
| SERTAD2 | SERTA domain containing 2 | 0.0130276 |
| NGLY1 | N-glycanase 1 | 0.0129407 |
| EDA | ectodysplasin A | 0.0128254 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0127088 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0126087 |
| TUFT1 | tuftelin 1 | 0.0126015 |
| CHSY1 | chondroitin sulfate synthase 1 | 0.012554 |
| LMNA | lamin A/C | 0.0123906 |
| SRP54 | signal recognition particle 54kDa | 0.0123872 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0123603 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.012349 |
| NRG1 | neuregulin 1 | 0.0122279 |
| EXOC6B | exocyst complex component 6B | 0.0122205 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0122121 |
| RLF | rearranged L-myc fusion | 0.0122025 |
| SQLE | squalene epoxidase | 0.0121448 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0121426 |
| EZR | ezrin | 0.0120573 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0119802 |
| SEPTIN9 | septin 9 | 0.0119063 |
| RNF19B | ring finger protein 19B | 0.0118135 |
| EML6 | echinoderm microtubule associated protein like 6 | 0.0117164 |
| THOC2 | THO complex 2 | 0.0115786 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0115681 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0112908 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0112764 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.340505 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.216482 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.214326 |
| MTSS1 | metastasis suppressor 1 | -0.194752 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.141049 |
| PDLIM5 | PDZ and LIM domain 5 | -0.128823 |
| SLC35F3 | solute carrier family 35, member F3 | -0.116698 |
| LMO7 | LIM domain 7 | -0.110227 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.100248 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0965909 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0951184 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.092641 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0889353 |
| RAI14 | retinoic acid induced 14 | -0.079118 |
| STC1 | stanniocalcin 1 | -0.0789983 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0725387 |
| INTS6 | integrator complex subunit 6 | -0.0691862 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0646648 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0638115 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0632813 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0628645 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0619651 |
| HMGA2 | high mobility group AT-hook 2 | -0.0616708 |
| RASAL2 | RAS protein activator like 2 | -0.0611716 |
| SULF2 | sulfatase 2 | -0.0602724 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0595446 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0590486 |
| PALLD | palladin, cytoskeletal associated protein | -0.0577552 |
| LAMC2 | laminin, gamma 2 | -0.0574024 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0570915 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0545173 |
| MT2A | metallothionein 2A | -0.0532278 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0532216 |
| PLS3 | plastin 3 | -0.052641 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0518299 |
| AHNAK | AHNAK nucleoprotein | -0.0510662 |
| LDHA | lactate dehydrogenase A | -0.0510109 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.050911 |
| CDK6 | cyclin-dependent kinase 6 | -0.0492652 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0489998 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.048557 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0484113 |
| MYOF | myoferlin | -0.0475192 |
| RNF217 | ring finger protein 217 | -0.0474491 |
| UTRN | utrophin | -0.0453107 |
| MECOM | MDS1 and EVI1 complex locus | -0.0452559 |
| RCOR1 | REST corepressor 1 | -0.0446367 |
| PODXL | podocalyxin-like | -0.0446104 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0440865 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0439602 |
| RPS8 | ribosomal protein S8 | -0.0422684 |
| PTK2 | protein tyrosine kinase 2 | -0.0409816 |
| PRSS23 | protease, serine, 23 | -0.04069 |
| SQSTM1 | sequestosome 1 | -0.0398787 |
| H1-0 | H1.0 linker histone | -0.0398407 |
| CNTNAP3 | contactin associated protein-like 3 | -0.0387473 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0375716 |
| CALR | calreticulin | -0.0374634 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0374579 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0372616 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0369949 |
| TNS3 | tensin 3 | -0.036969 |
| RPS6 | ribosomal protein S6 | -0.036721 |
| EFNA5 | ephrin-A5 | -0.0367114 |
| TSC22D1 | TSC22 domain family, member 1 | -0.036399 |
| DGKH | diacylglycerol kinase, eta | -0.0361501 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0360967 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0358345 |
| JMJD1C | jumonji domain containing 1C | -0.035833 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -0.0357886 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0353221 |
| RIGI | RNA sensor RIG-I | -0.034832 |
| DOK5 | docking protein 5 | -0.0339063 |
| RPL37 | ribosomal protein L37 | -0.0338953 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0336876 |
| CLIC4 | chloride intracellular channel 4 | -0.0336675 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0332081 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0328831 |
| KIAA1671 | KIAA1671 | -0.0325184 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0322597 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0321911 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0317948 |
| RPL11 | ribosomal protein L11 | -0.0317416 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0315988 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0313483 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0312666 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0310261 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0308026 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0306284 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0306161 |
| SULF1 | sulfatase 1 | -0.0304386 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0304289 |
| EXOC4 | exocyst complex component 4 | -0.029818 |
| IFI44L | interferon-induced protein 44-like | -0.0296344 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0296168 |
| EGFR | epidermal growth factor receptor | -0.0294337 |
| ANXA2 | annexin A2 | -0.0291373 |
| RAD51B | RAD51 paralog B | -0.029086 |
| HDAC9 | histone deacetylase 9 | -0.0290165 |
| RPS12 | ribosomal protein S12 | -0.0289211 |
