| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Panobinostat perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Panobinostat_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0714062 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0607927 |
| FAT1 | FAT atypical cadherin 1 | 0.0600408 |
| ASPH | aspartate beta-hydroxylase | 0.0581989 |
| PLEC | plectin | 0.0552247 |
| FLNB | filamin B, beta | 0.0524913 |
| LMO7 | LIM domain 7 | 0.0510562 |
| SEPTIN9 | septin 9 | 0.0463314 |
| CMIP | c-Maf inducing protein | 0.0435765 |
| DST | dystonin | 0.0392819 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0392554 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0386036 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0383781 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0366621 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0365978 |
| ATXN1 | ataxin 1 | 0.0361313 |
| SMAD3 | SMAD family member 3 | 0.0360775 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0360007 |
| DSPP | dentin sialophosphoprotein | 0.0353125 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0345547 |
| EZR | ezrin | 0.0342608 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0334149 |
| FRMD5 | FERM domain containing 5 | 0.0324323 |
| RUNX1 | runt-related transcription factor 1 | 0.0314493 |
| WWC1 | WW and C2 domain containing 1 | 0.0306182 |
| ACTN4 | actinin, alpha 4 | 0.0298093 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0297249 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0296863 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0294168 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0291738 |
| EXT1 | exostosin glycosyltransferase 1 | 0.029168 |
| NDRG1 | N-myc downstream regulated 1 | 0.0280693 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0277363 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0269489 |
| RNF213 | ring finger protein 213 | 0.0267908 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0266144 |
| CTBP2 | C-terminal binding protein 2 | 0.0261216 |
| FOXP1 | forkhead box P1 | 0.0258636 |
| MECOM | MDS1 and EVI1 complex locus | 0.0252309 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0252076 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0251247 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0251018 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0250412 |
| VMP1 | vacuole membrane protein 1 | 0.0248805 |
| RAD51B | RAD51 paralog B | 0.024446 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0233967 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0230023 |
| HKDC1 | hexokinase domain containing 1 | 0.0229152 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0228949 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.022594 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.022541 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0225013 |
| PPL | periplakin | 0.0221405 |
| KIAA1217 | KIAA1217 | 0.0221395 |
| EDA | ectodysplasin A | 0.0219972 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0219527 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0215957 |
| FOXO3 | forkhead box O3 | 0.0214644 |
| AHNAK | AHNAK nucleoprotein | 0.0210518 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0207681 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0207177 |
| ANXA1 | annexin A1 | 0.0206671 |
| RAB10 | RAB10, member RAS oncogene family | 0.0206596 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0206409 |
| PGK1 | phosphoglycerate kinase 1 | 0.0202039 |
| EXOC6B | exocyst complex component 6B | 0.0200615 |
| LIPH | lipase, member H | 0.0200552 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0197041 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0195675 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0195628 |
| SIK3 | SIK family kinase 3 | 0.0192885 |
| EFNA5 | ephrin-A5 | 0.0192038 |
| MYO15B | myosin XVB | 0.0191881 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0191646 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0191084 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0189893 |
| INTS6 | integrator complex subunit 6 | 0.0188978 |
| OXR1 | oxidation resistance 1 | 0.0188087 |
| APP | amyloid beta (A4) precursor protein | 0.0186343 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0184029 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0183033 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0182768 |
| NONO | non-POU domain containing, octamer-binding | 0.0182451 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | 0.018229 |
| SKAP1 | src kinase associated phosphoprotein 1 | 0.0180277 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.018023 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0178568 |
| DENND4A | DENN/MADD domain containing 4A | 0.0173095 |
| EMP1 | epithelial membrane protein 1 | 0.0172408 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0171966 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0168948 |
| SYNJ2 | synaptojanin 2 | 0.0168874 |
| KLHL29 | kelch-like family member 29 | 0.0168405 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0167266 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0167199 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0166524 |
| SBF2 | SET binding factor 2 | 0.0165531 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0163185 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0160311 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0157802 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.209658 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.175951 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.10735 |
| NPSR1 | neuropeptide S receptor 1 | -0.106389 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0786806 |
| S100A6 | S100 calcium binding protein A6 | -0.0724509 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0662512 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0635613 |
| TMSB10 | thymosin beta 10 | -0.0563404 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0563225 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0557653 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0546149 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | -0.0529747 |
| B2M | beta-2-microglobulin | -0.0488746 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.046085 |
| AGR3 | anterior gradient 3 | -0.0458656 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0455991 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0455749 |
| GOLGA4 | golgin A4 | -0.0415416 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0399727 |
| RPLP1 | ribosomal protein, large, P1 | -0.0397437 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0396662 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0393459 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0389967 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0376467 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0373108 |
| ATF5 | activating transcription factor 5 | -0.0351618 |
| AGR2 | anterior gradient 2 | -0.0338725 |
| GSTP1 | glutathione S-transferase pi 1 | -0.033769 |
| RPS3 | ribosomal protein S3 | -0.0334245 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0332119 |
| RPL35 | ribosomal protein L35 | -0.0331778 |
| TMEM123 | transmembrane protein 123 | -0.0328214 |
| RPL12 | ribosomal protein L12 | -0.0327327 |
| CALR | calreticulin | -0.0327145 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0318362 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0313472 |
| RPL23 | ribosomal protein L23 | -0.0306567 |
| RPL8 | ribosomal protein L8 | -0.0304098 |
| KRT18 | keratin 18, type I | -0.030315 |
| RPS19 | ribosomal protein S19 | -0.0302928 |
| S100A9 | S100 calcium binding protein A9 | -0.0296739 |
| GNAS | GNAS complex locus | -0.0291892 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.028976 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.028784 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0287253 |
| S100A10 | S100 calcium binding protein A10 | -0.0285514 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.02845 |
| POTEF | POTE ankyrin domain family, member F | -0.0280844 |
| PCBP2 | poly(rC) binding protein 2 | -0.0279612 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0279016 |
| CLU | clusterin | -0.0277125 |
| HYOU1 | hypoxia up-regulated 1 | -0.0270219 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0266254 |
| RPS5 | ribosomal protein S5 | -0.0262457 |
| RPS21 | ribosomal protein S21 | -0.026071 |
| RBM39 | RNA binding motif protein 39 | -0.0258051 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0254358 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0252283 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0247766 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0246944 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0246524 |
| RPL18 | ribosomal protein L18 | -0.0240889 |
| YBX1 | Y box binding protein 1 | -0.0240177 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0236038 |
| RPL28 | ribosomal protein L28 | -0.023572 |
| PFN1 | profilin 1 | -0.0231954 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0229094 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | -0.0225102 |
| CBX3 | chromobox homolog 3 | -0.0222814 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0219898 |
| CANX | calnexin | -0.021706 |
| CLDN7 | claudin 7 | -0.0215242 |
| MUC17 | mucin 17, cell surface associated | -0.0214247 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.021401 |
| S100A11 | S100 calcium binding protein A11 | -0.021094 |
| SNX9 | sorting nexin 9 | -0.0208689 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0206393 |
| FTL | ferritin, light polypeptide | -0.020415 |
| KLK10 | kallikrein-related peptidase 10 | -0.0203795 |
| RPS6 | ribosomal protein S6 | -0.0202906 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0201412 |
| WDR45B | WD repeat domain 45B | -0.0199397 |
| SET | SET nuclear proto-oncogene | -0.0198003 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0197753 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0197055 |
| JPT1 | Jupiter microtubule associated homolog 1 | -0.0194776 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0192202 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0188551 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.0186721 |
| DSG2 | desmoglein 2 | -0.0185736 |
| DEK | DEK proto-oncogene | -0.0183581 |
| APOL6 | apolipoprotein L, 6 | -0.0183416 |
| TENM1 | teneurin transmembrane protein 1 | -0.0182269 |
| RPLP0 | ribosomal protein, large, P0 | -0.0178648 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0178512 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0177339 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.0176645 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0175303 |
| TES | testin LIM domain protein | -0.0175022 |
