| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Panobinostat perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Panobinostat_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0917403 |
| TXNRD1 | thioredoxin reductase 1 | 0.0781007 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0732782 |
| SMYD3 | SET and MYND domain containing 3 | 0.0666894 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0658182 |
| VCL | vinculin | 0.0643827 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.059651 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0591626 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0553788 |
| RAI1 | retinoic acid induced 1 | 0.0542737 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0494911 |
| SPAG9 | sperm associated antigen 9 | 0.0491658 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0479665 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0454404 |
| TMEM41B | transmembrane protein 41B | 0.0446574 |
| FLNB | filamin B, beta | 0.0425569 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.04171 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0401989 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0398113 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0387199 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0385135 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0384347 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0381914 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0381303 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0380867 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0374021 |
| EMP1 | epithelial membrane protein 1 | 0.0364264 |
| HPCAL1 | hippocalcin-like 1 | 0.0358975 |
| EREG | epiregulin | 0.0358295 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0351548 |
| TFRC | transferrin receptor | 0.0349995 |
| TYW1B | tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae) | 0.0348855 |
| CENPF | centromere protein F, 350/400kDa | 0.0339633 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0334035 |
| RTN4 | reticulon 4 | 0.0331179 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0329781 |
| RTTN | rotatin | 0.0329469 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0322508 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0319966 |
| WDR26 | WD repeat domain 26 | 0.0319019 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0318285 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0316273 |
| RSU1 | Ras suppressor protein 1 | 0.0316127 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0312487 |
| LPIN1 | lipin 1 | 0.0311959 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.0311274 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0309023 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0307136 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0301465 |
| MKI67 | marker of proliferation Ki-67 | 0.0300465 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0298382 |
| CORO1C | coronin, actin binding protein, 1C | 0.0297425 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) | 0.0293146 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0291904 |
| SCGB1D1 | secretoglobin, family 1D, member 1 | 0.0290859 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0288285 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0284847 |
| ZNF217 | zinc finger protein 217 | 0.0284371 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0282945 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0281055 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.0278849 |
| SRPK2 | SRSF protein kinase 2 | 0.0275593 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0272409 |
| RCOR1 | REST corepressor 1 | 0.0270749 |
| HSPA8 | heat shock 70kDa protein 8 | 0.02694 |
| PLEC | plectin | 0.0268621 |
| TMSB4X | thymosin beta 4, X-linked | 0.0266684 |
| UTRN | utrophin | 0.0265826 |
| CMIP | c-Maf inducing protein | 0.0263316 |
| EXOC6B | exocyst complex component 6B | 0.0262344 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0260727 |
| APP | amyloid beta (A4) precursor protein | 0.0260082 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.025946 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0258262 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0258034 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0257142 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0255775 |
| KDM5A | lysine (K)-specific demethylase 5A | 0.0252193 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0252114 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0251709 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0251254 |
| CAPRIN2 | caprin family member 2 | 0.0248411 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0245994 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0245361 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0245303 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 | 0.0245204 |
| IPO7 | importin 7 | 0.0239818 |
| TOR1AIP2 | torsin A interacting protein 2 | 0.0239401 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0238314 |
| R3HDM1 | R3H domain containing 1 | 0.0238149 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0237532 |
| AHNAK | AHNAK nucleoprotein | 0.0236615 |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 | 0.0236522 |
| NONO | non-POU domain containing, octamer-binding | 0.023645 |
| SNX29 | sorting nexin 29 | 0.0234621 |
| RRM2 | ribonucleotide reductase M2 | 0.0232297 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0230934 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0230657 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.023 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0229526 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.224986 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.169901 |
| MT2A | metallothionein 2A | -0.115155 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.106124 |
| TMSB10 | thymosin beta 10 | -0.0781301 |
| FTL | ferritin, light polypeptide | -0.076212 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0678734 |
| PTMA | prothymosin, alpha | -0.0661286 |
| CALR | calreticulin | -0.0661026 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0644581 |
| CD44 | CD44 molecule (Indian blood group) | -0.0634835 |
| VIM | vimentin | -0.0629184 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0620949 |
| MYOF | myoferlin | -0.0601488 |
| EFNA5 | ephrin-A5 | -0.0576288 |
| HLA-B | major histocompatibility complex, class I, B | -0.0563981 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0516154 |
| TNS3 | tensin 3 | -0.0507123 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0494818 |
| RPL35A | ribosomal protein L35a | -0.0488222 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0483925 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0476775 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0471794 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0463349 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0431845 |
| RPS6 | ribosomal protein S6 | -0.0408919 |
| DST | dystonin | -0.0407295 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0396506 |
| TSC22D1 | TSC22 domain family, member 1 | -0.039324 |
| RPS19 | ribosomal protein S19 | -0.0381293 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.037958 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0372214 |
| RPL37A | ribosomal protein L37a | -0.0369295 |
| HMGA1 | high mobility group AT-hook 1 | -0.0363429 |
| TXNIP | thioredoxin interacting protein | -0.0362026 |
| MT1X | metallothionein 1X | -0.0357553 |
| POTEF | POTE ankyrin domain family, member F | -0.0354286 |
| RPS8 | ribosomal protein S8 | -0.0354275 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0350661 |
| RPL36 | ribosomal protein L36 | -0.0342237 |
| PTK2 | protein tyrosine kinase 2 | -0.0333794 |
| RPLP1 | ribosomal protein, large, P1 | -0.032912 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0328469 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0326658 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0323761 |
| EPHA4 | EPH receptor A4 | -0.0321596 |
| ZNF292 | zinc finger protein 292 | -0.031906 |
| B2M | beta-2-microglobulin | -0.0318897 |
| HLA-A | major histocompatibility complex, class I, A | -0.0316504 |
| MT1E | metallothionein 1E | -0.0312504 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0311618 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0306403 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0305012 |
| RBM39 | RNA binding motif protein 39 | -0.0304646 |
| RPS12 | ribosomal protein S12 | -0.0302812 |
| RPL31 | ribosomal protein L31 | -0.0299275 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0297667 |
| PRELID2 | PRELI domain containing 2 | -0.0294434 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0293707 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0286116 |
| PDE8A | phosphodiesterase 8A | -0.0285565 |
| RPL12 | ribosomal protein L12 | -0.0283732 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0283351 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0280928 |
| PDE10A | phosphodiesterase 10A | -0.0272052 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.026329 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0261213 |
| RPL23 | ribosomal protein L23 | -0.0259805 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0259044 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0257288 |
| RPL28 | ribosomal protein L28 | -0.0251263 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0250896 |
| ZNF638 | zinc finger protein 638 | -0.0249688 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0249638 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0249414 |
| SLK | STE20-like kinase | -0.0246116 |
| RPS29 | ribosomal protein S29 | -0.0239731 |
| RPLP2 | ribosomal protein, large, P2 | -0.0238964 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0231844 |
| GOLGA4 | golgin A4 | -0.0230683 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0229199 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0225594 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0223616 |
| RPL37 | ribosomal protein L37 | -0.0221145 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0220111 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0219329 |
| GNAS | GNAS complex locus | -0.0218743 |
| S100A9 | S100 calcium binding protein A9 | -0.0213336 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.021248 |
| PLIN2 | perilipin 2 | -0.0208141 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0207938 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0206156 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0205178 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0203751 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0201789 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0201366 |
| RPS23 | ribosomal protein S23 | -0.0199853 |
| TP63 | tumor protein p63 | -0.0199542 |
| RSF1 | remodeling and spacing factor 1 | -0.01978 |
| NDRG1 | N-myc downstream regulated 1 | -0.019776 |
