| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Panobinostat perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Panobinostat_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | 0.0639937 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0604016 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0568352 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0539563 |
| SYT1 | synaptotagmin I | 0.0503837 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.047443 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0467646 |
| TXNRD1 | thioredoxin reductase 1 | 0.0446515 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0419215 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.035678 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0343479 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.0332966 |
| EXOC6B | exocyst complex component 6B | 0.0296549 |
| TYW1B | tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae) | 0.0289372 |
| ASPH | aspartate beta-hydroxylase | 0.0275657 |
| MYO10 | myosin X | 0.0269695 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0269202 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0261791 |
| RSU1 | Ras suppressor protein 1 | 0.0261514 |
| GPHN | gephyrin | 0.0260734 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0254305 |
| PRKCA | protein kinase C, alpha | 0.0248772 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0245286 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0244107 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0243746 |
| VCL | vinculin | 0.0241815 |
| SMYD3 | SET and MYND domain containing 3 | 0.023987 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0233403 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0232317 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0226683 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0226504 |
| FRMD5 | FERM domain containing 5 | 0.0225779 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0225038 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0224359 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0219997 |
| TAOK3 | TAO kinase 3 | 0.0219397 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0216812 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0213197 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0212557 |
| APP | amyloid beta (A4) precursor protein | 0.0212522 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0209491 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0209445 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0207393 |
| AUTS2 | autism susceptibility candidate 2 | 0.0205619 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0205183 |
| TUSC3 | tumor suppressor candidate 3 | 0.020474 |
| DNM3 | dynamin 3 | 0.0204278 |
| ENAH | enabled homolog (Drosophila) | 0.0201961 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0199878 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0199504 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0197984 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0197652 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0196318 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | 0.0195276 |
| STK4 | serine/threonine kinase 4 | 0.0192651 |
| SPAG9 | sperm associated antigen 9 | 0.0192184 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0191014 |
| MIPOL1 | mirror-image polydactyly 1 | 0.0187859 |
| AFG2A | AFG2 AAA ATPase homolog A | 0.0186438 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0182312 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 | 0.0180384 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0180301 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.0180259 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa | 0.0179466 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0178987 |
| PLEC | plectin | 0.0178972 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.017776 |
| PCNX2 | pecanex 2 | 0.0176763 |
| SFTPA2 | surfactant protein A2 | 0.0176441 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | 0.0174089 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0169599 |
| R3HDM1 | R3H domain containing 1 | 0.0168448 |
| CEP128 | centrosomal protein 128kDa | 0.0167713 |
| RANBP17 | RAN binding protein 17 | 0.0167117 |
| CORO1C | coronin, actin binding protein, 1C | 0.016677 |
| TNPO1 | transportin 1 | 0.0164254 |
| TENM1 | teneurin transmembrane protein 1 | 0.0163619 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0163562 |
| ACTN4 | actinin, alpha 4 | 0.0163526 |
| CMIP | c-Maf inducing protein | 0.0163397 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0162297 |
| FAM107B | family with sequence similarity 107, member B | 0.016227 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0160781 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) | 0.0159942 |
| SERTAD2 | SERTA domain containing 2 | 0.0159895 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0158151 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0157238 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0156325 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0155668 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0155591 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0155273 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0155102 |
| HIP1 | huntingtin interacting protein 1 | 0.0154774 |
| MAPRE2 | microtubule-associated protein, RP/EB family, member 2 | 0.015401 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0153291 |
| MRTFA | myocardin related transcription factor A | 0.0152459 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 | 0.0152364 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.0152157 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.015133 |
| HDAC4 | histone deacetylase 4 | 0.0151238 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.154103 |
| FNDC3B | fibronectin type III domain containing 3B | -0.147298 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.135829 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.13272 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.125092 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.118625 |
| RBM39 | RNA binding motif protein 39 | -0.0931514 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0894224 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0816396 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0782861 |
| LOX | lysyl oxidase | -0.0749978 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0714492 |
| GOLGA4 | golgin A4 | -0.0701034 |
| USP34 | ubiquitin specific peptidase 34 | -0.0693835 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0675343 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0660606 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0650161 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.063189 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0630355 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0622935 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.06193 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.06186 |
| NDRG1 | N-myc downstream regulated 1 | -0.0599717 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0590313 |
| VIM | vimentin | -0.0567129 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0565291 |
| TMSB10 | thymosin beta 10 | -0.0565001 |
| OSMR | oncostatin M receptor | -0.0535556 |
| NRP1 | neuropilin 1 | -0.0531876 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0524845 |
| CDCP1 | CUB domain containing protein 1 | -0.0524049 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0507769 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0506564 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0500288 |
| GPC6 | glypican 6 | -0.0480235 |
| ZNF292 | zinc finger protein 292 | -0.0476158 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.046101 |
| PRELID2 | PRELI domain containing 2 | -0.0435072 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0434774 |
| PCBP2 | poly(rC) binding protein 2 | -0.0426691 |
| FTL | ferritin, light polypeptide | -0.0426375 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0424274 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.0424112 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0421999 |
| RUNX2 | runt-related transcription factor 2 | -0.0406607 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | -0.0402431 |
| EFNA5 | ephrin-A5 | -0.0400484 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.039794 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0396375 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.039484 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0386871 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0383939 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0374147 |
| MEF2A | myocyte enhancer factor 2A | -0.037135 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0363462 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.036082 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0360242 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0358812 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0354859 |
| FAM13A | family with sequence similarity 13, member A | -0.0342103 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0341948 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0333978 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0332975 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.033272 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0327095 |
| KYNU | kynureninase | -0.0323237 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0321751 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0320719 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0318817 |
| CDH13 | cadherin 13 | -0.0316722 |
| RPLP1 | ribosomal protein, large, P1 | -0.0312307 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0309893 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0304622 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0304591 |
| COPA | coatomer protein complex, subunit alpha | -0.0302712 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0302695 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0302196 |
| RAI14 | retinoic acid induced 14 | -0.0301821 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0301171 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.030064 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0300198 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0299579 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0296896 |
| JMJD1C | jumonji domain containing 1C | -0.0294241 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0292324 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0291806 |
| SNX9 | sorting nexin 9 | -0.0284993 |
| HMGA2 | high mobility group AT-hook 2 | -0.0283367 |
| CALR | calreticulin | -0.0282672 |
| NF1 | neurofibromin 1 | -0.0281855 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0281467 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0279944 |
| MT2A | metallothionein 2A | -0.0278005 |
| PTMA | prothymosin, alpha | -0.0275603 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0274779 |
| HAS2 | hyaluronan synthase 2 | -0.0271676 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0268932 |
| CD109 | CD109 molecule | -0.0268733 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0264221 |
| CANX | calnexin | -0.0263392 |
