| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Panobinostat perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Panobinostat_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.108979 |
| SMYD3 | SET and MYND domain containing 3 | 0.0940682 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0906516 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0806649 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0797641 |
| FTL | ferritin, light polypeptide | 0.070666 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0681875 |
| PLEC | plectin | 0.0665238 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0603306 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0600088 |
| TMSB10 | thymosin beta 10 | 0.0600005 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0591152 |
| LAMC2 | laminin, gamma 2 | 0.0573162 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0572721 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0564647 |
| MT2A | metallothionein 2A | 0.0530248 |
| GPHN | gephyrin | 0.0506078 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | 0.0503023 |
| CNKSR3 | CNKSR family member 3 | 0.0473619 |
| TUFT1 | tuftelin 1 | 0.0468486 |
| SYT1 | synaptotagmin I | 0.0451965 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0438619 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0424558 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.041781 |
| LMNA | lamin A/C | 0.0402991 |
| WWC1 | WW and C2 domain containing 1 | 0.040203 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0383629 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0383176 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0381159 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0379785 |
| TUSC3 | tumor suppressor candidate 3 | 0.0377184 |
| MSN | moesin | 0.0377164 |
| TPD52 | tumor protein D52 | 0.0377017 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0376901 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0375459 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0373013 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0370767 |
| ANKRD28 | ankyrin repeat domain 28 | 0.036965 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.03681 |
| TMSB4X | thymosin beta 4, X-linked | 0.0367482 |
| SRPK2 | SRSF protein kinase 2 | 0.0363297 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.035878 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0358653 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0349014 |
| RPS23 | ribosomal protein S23 | 0.0347199 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0342611 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0330874 |
| SBF2 | SET binding factor 2 | 0.0324079 |
| STK24 | serine/threonine kinase 24 | 0.03202 |
| TAOK3 | TAO kinase 3 | 0.0319468 |
| RUNX1 | runt-related transcription factor 1 | 0.0314432 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0312995 |
| ASPH | aspartate beta-hydroxylase | 0.0311119 |
| RAD51B | RAD51 paralog B | 0.0310427 |
| RPS19 | ribosomal protein S19 | 0.0308997 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0306257 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0303233 |
| GOLGA4 | golgin A4 | 0.0302704 |
| MYO10 | myosin X | 0.0299558 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0297672 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0297289 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0297232 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.0295578 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0295497 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0295276 |
| VCL | vinculin | 0.0293066 |
| RANBP17 | RAN binding protein 17 | 0.0292405 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0292332 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0290616 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0290474 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.028975 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 0.0288565 |
| RPS29 | ribosomal protein S29 | 0.0286818 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.0282804 |
| MITF | microphthalmia-associated transcription factor | 0.0274603 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0274413 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0274258 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0273021 |
| H1-4 | H1.4 linker histone, cluster member | 0.0272421 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0269957 |
| DST | dystonin | 0.0268766 |
| LAMB3 | laminin, beta 3 | 0.0267636 |
| RPS6 | ribosomal protein S6 | 0.0267146 |
| BMP2K | BMP2 inducible kinase | 0.0266381 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0263592 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0262846 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0260769 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0260213 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0258909 |
| FOXP1 | forkhead box P1 | 0.0257525 |
| RPL37 | ribosomal protein L37 | 0.0255852 |
| NONO | non-POU domain containing, octamer-binding | 0.025537 |
| G0S2 | G0/G1 switch 2 | 0.0254932 |
| LRRC1 | leucine rich repeat containing 1 | 0.0253548 |
| PALLD | palladin, cytoskeletal associated protein | 0.0253378 |
| TNPO1 | transportin 1 | 0.0252271 |
| EVI5 | ecotropic viral integration site 5 | 0.0250562 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | 0.0250211 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0248289 |
| TXNRD1 | thioredoxin reductase 1 | 0.0247853 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | -0.181115 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.158755 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.134519 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.124133 |
| GRB10 | growth factor receptor-bound protein 10 | -0.120699 |
| NDRG1 | N-myc downstream regulated 1 | -0.120501 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0854001 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.082139 |
| POTEF | POTE ankyrin domain family, member F | -0.072221 |
| LMO7 | LIM domain 7 | -0.0677844 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0650369 |
| ACTG1 | actin gamma 1 | -0.0629011 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0618172 |
| CALR | calreticulin | -0.0603345 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.060149 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.058408 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.055293 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0528929 |
| SQSTM1 | sequestosome 1 | -0.0527797 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0520373 |
| AREG | amphiregulin | -0.0514057 |
| LDHA | lactate dehydrogenase A | -0.050146 |
| FBXO32 | F-box protein 32 | -0.0491204 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0483668 |
| PTMA | prothymosin, alpha | -0.0474731 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0464726 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0448738 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0446358 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.044537 |
| MYOF | myoferlin | -0.0438693 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0429164 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.042339 |
| RYBP | RING1 and YY1 binding protein | -0.0414516 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.041115 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0404144 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0403201 |
| RBM39 | RNA binding motif protein 39 | -0.0396044 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0389677 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0388846 |
| ZNF292 | zinc finger protein 292 | -0.0387113 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | -0.0385119 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0375101 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0373655 |
| ARRDC3 | arrestin domain containing 3 | -0.0368668 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0365277 |
| WDFY3 | WD repeat and FYVE domain containing 3 | -0.0362081 |
| TFG | TRK-fused gene | -0.0360279 |
| CD109 | CD109 molecule | -0.0358536 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0340048 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0338396 |
| EFNA5 | ephrin-A5 | -0.0334184 |
| H1-0 | H1.0 linker histone | -0.0334098 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | -0.0328624 |
| FAM3C | family with sequence similarity 3, member C | -0.0317891 |
| GNAS | GNAS complex locus | -0.0313314 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0299075 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0297729 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.029547 |
| CDK17 | cyclin-dependent kinase 17 | -0.0286417 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0285605 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0284594 |
| TLK2 | tousled-like kinase 2 | -0.0284594 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0284372 |
| CD2AP | CD2-associated protein | -0.028399 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0280659 |
| NCOA2 | nuclear receptor coactivator 2 | -0.0279826 |
| MX1 | MX dynamin-like GTPase 1 | -0.0275819 |
| ANXA2 | annexin A2 | -0.0274854 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0272634 |
| MYO6 | myosin VI | -0.0268361 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0266723 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0263241 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0260377 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0258552 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0257244 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.025487 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0253882 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0252786 |
| PTK2 | protein tyrosine kinase 2 | -0.0251854 |
| PLSCR1 | phospholipid scramblase 1 | -0.0250343 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0249758 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0248855 |
| NRP1 | neuropilin 1 | -0.0246718 |
| YAP1 | Yes-associated protein 1 | -0.02427 |
| CDCP1 | CUB domain containing protein 1 | -0.0240552 |
| SNX9 | sorting nexin 9 | -0.0240198 |
| RNASE3 | ribonuclease, RNase A family, 3 | -0.0238013 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0236682 |
| OCLN | occludin | -0.0235662 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0235282 |
| CDC73 | cell division cycle 73 | -0.0232914 |
| CCND1 | cyclin D1 | -0.0229763 |
| JUP | junction plakoglobin | -0.0226006 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0224862 |
| WASF2 | WAS protein family, member 2 | -0.0223736 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | -0.0218899 |
| RASA2 | RAS p21 protein activator 2 | -0.0218337 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0215363 |
| DSG2 | desmoglein 2 | -0.0214291 |
| COPA | coatomer protein complex, subunit alpha | -0.0212754 |
