| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Panobinostat perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Panobinostat_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.105414 |
| TXNRD1 | thioredoxin reductase 1 | 0.0767868 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0687393 |
| GRAMD1B | GRAM domain containing 1B | 0.066677 |
| FLNB | filamin B, beta | 0.0467983 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0426131 |
| PTGR1 | prostaglandin reductase 1 | 0.0351263 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0329696 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.029418 |
| RTN4 | reticulon 4 | 0.0264993 |
| MAP1B | microtubule-associated protein 1B | 0.0253946 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0249291 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0248517 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0243021 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0240525 |
| ANXA1 | annexin A1 | 0.023614 |
| PTEN | phosphatase and tensin homolog | 0.0232156 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0227118 |
| MCL1 | myeloid cell leukemia 1 | 0.0218523 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0210077 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0208556 |
| ENAH | enabled homolog (Drosophila) | 0.0206878 |
| IGF1R | insulin-like growth factor 1 receptor | 0.019333 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0193189 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0188676 |
| RAI1 | retinoic acid induced 1 | 0.0185341 |
| NDRG1 | N-myc downstream regulated 1 | 0.018314 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0181091 |
| PCNX2 | pecanex 2 | 0.0176092 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0174844 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0169952 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0168584 |
| PRKCA | protein kinase C, alpha | 0.0158635 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0157296 |
| BMERB1 | bMERB domain containing 1 | 0.0156132 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0155774 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.015346 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0151783 |
| ITGA6 | integrin, alpha 6 | 0.0151446 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0149361 |
| SYT1 | synaptotagmin I | 0.0148563 |
| MSN | moesin | 0.0148519 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0145586 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0145472 |
| COL4A6 | collagen, type IV, alpha 6 | 0.0140794 |
| VMP1 | vacuole membrane protein 1 | 0.0139438 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0133847 |
| CUL4B | cullin 4B | 0.0133222 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0131711 |
| CD44 | CD44 molecule (Indian blood group) | 0.0131316 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0128993 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0127344 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.012342 |
| TNPO1 | transportin 1 | 0.0120215 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0117822 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0115557 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0115497 |
| PYGL | phosphorylase, glycogen, liver | 0.0115331 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0115319 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0115198 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0114964 |
| ADAM23 | ADAM metallopeptidase domain 23 | 0.0111929 |
| RARB | retinoic acid receptor, beta | 0.0109946 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | 0.0109262 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.010897 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0108265 |
| CNTN1 | contactin 1 | 0.0108205 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0107439 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 0.0107133 |
| SEPTIN9 | septin 9 | 0.0107083 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0106948 |
| RAB10 | RAB10, member RAS oncogene family | 0.0106301 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0105614 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0104862 |
| ATP13A3 | ATPase type 13A3 | 0.010474 |
| TUSC3 | tumor suppressor candidate 3 | 0.0104107 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0104066 |
| EDA | ectodysplasin A | 0.0103836 |
| ITGAV | integrin, alpha V | 0.0103749 |
| RASAL2 | RAS protein activator like 2 | 0.0103307 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0102127 |
| NGLY1 | N-glycanase 1 | 0.0101508 |
| NFIA | nuclear factor I/A | 0.0100467 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.00998888 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.00987599 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | 0.00979219 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.00977428 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00977163 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.00972092 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.00971971 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.00970525 |
| FMNL2 | formin-like 2 | 0.00966851 |
| SSH2 | slingshot protein phosphatase 2 | 0.00953794 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.00950016 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.00944559 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | 0.00943241 |
| PLEC | plectin | 0.00930753 |
| ACTN1 | actinin, alpha 1 | 0.00923598 |
| ANKRD17 | ankyrin repeat domain 17 | 0.00923243 |
| CHML | choroideremia-like (Rab escort protein 2) | 0.00923003 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.226346 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.209223 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.128823 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.103718 |
| CDH13 | cadherin 13 | -0.0846359 |
| COL5A2 | collagen, type V, alpha 2 | -0.0816532 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0650826 |
| PDE10A | phosphodiesterase 10A | -0.0641712 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0536399 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0527394 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.048649 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0482501 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.044861 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0434876 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0375051 |
| RPLP1 | ribosomal protein, large, P1 | -0.0361092 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0336824 |
| PTMA | prothymosin, alpha | -0.0327605 |
| FN1 | fibronectin 1 | -0.032135 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0318955 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0317335 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0317099 |
| RPS6 | ribosomal protein S6 | -0.0314679 |
| VIM | vimentin | -0.0314403 |
| CALR | calreticulin | -0.0274056 |
| RPS8 | ribosomal protein S8 | -0.0262683 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.0260399 |
| FTL | ferritin, light polypeptide | -0.0257914 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0257391 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0255889 |
| TMSB10 | thymosin beta 10 | -0.0254515 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0245899 |
| CHL1 | cell adhesion molecule L1-like | -0.0244661 |
| NRCAM | neuronal cell adhesion molecule | -0.0244295 |
| RPS24 | ribosomal protein S24 | -0.0239921 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | -0.0239369 |
| PCBP3 | poly(rC) binding protein 3 | -0.0230086 |
| SQSTM1 | sequestosome 1 | -0.0229473 |
| RPL26 | ribosomal protein L26 | -0.0228374 |
| RPL37A | ribosomal protein L37a | -0.0224727 |
| SMYD3 | SET and MYND domain containing 3 | -0.0219998 |
| RPL31 | ribosomal protein L31 | -0.0216524 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0216378 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0215191 |
| RPL35A | ribosomal protein L35a | -0.0213017 |
| RPL12 | ribosomal protein L12 | -0.0210753 |
| PRELID2 | PRELI domain containing 2 | -0.0208483 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | -0.0208237 |
| RPS12 | ribosomal protein S12 | -0.0202628 |
| LSAMP | limbic system-associated membrane protein | -0.0202087 |
| RPL23 | ribosomal protein L23 | -0.0201641 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0198223 |
| CANX | calnexin | -0.0197324 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0191291 |
| RPS19 | ribosomal protein S19 | -0.0190518 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0185588 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0184956 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0184899 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0182568 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0182467 |
| RPL34 | ribosomal protein L34 | -0.018122 |
| RPS23 | ribosomal protein S23 | -0.0177396 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0175662 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0174565 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0171907 |
| RPLP0 | ribosomal protein, large, P0 | -0.0171231 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.01704 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0169439 |
| MAP7 | microtubule-associated protein 7 | -0.0165551 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0164955 |
| GNAS | GNAS complex locus | -0.0163228 |
| KIAA0825 | KIAA0825 | -0.016261 |
| RPL19 | ribosomal protein L19 | -0.0161998 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0161322 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0159154 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit | -0.0158048 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0158025 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0157955 |
| RPL9 | ribosomal protein L9 | -0.0157668 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0155625 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | -0.0154102 |
| AREG | amphiregulin | -0.0151825 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0150792 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0149956 |
| CUX1 | cut-like homeobox 1 | -0.01498 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0149178 |
| RPS27A | ribosomal protein S27a | -0.0146033 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.014517 |
| RPS27 | ribosomal protein S27 | -0.0144897 |
| RPS25 | ribosomal protein S25 | -0.0143756 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0142732 |
| RPL37 | ribosomal protein L37 | -0.014216 |
| RPLP2 | ribosomal protein, large, P2 | -0.0142126 |
| RPL11 | ribosomal protein L11 | -0.0141917 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0141117 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0140501 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0140388 |
| RBM39 | RNA binding motif protein 39 | -0.0140249 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0136945 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0136567 |
