| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Panobinostat perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Panobinostat_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0415039 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.041398 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0406072 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0312598 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0277147 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0276376 |
| ACTN4 | actinin, alpha 4 | 0.0275402 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.026029 |
| TP63 | tumor protein p63 | 0.0255748 |
| CALN1 | calneuron 1 | 0.0250996 |
| ZFPM2 | zinc finger protein, FOG family member 2 | 0.0247764 |
| SRPK2 | SRSF protein kinase 2 | 0.02351 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0230245 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0229782 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0228461 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0227314 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0226185 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0225308 |
| LUZP1 | leucine zipper protein 1 | 0.0219363 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0216458 |
| PHACTR4 | phosphatase and actin regulator 4 | 0.0214023 |
| PGPEP1L | pyroglutamyl-peptidase I-like | 0.0211727 |
| ZNF207 | zinc finger protein 207 | 0.0209119 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 | 0.0207011 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0204451 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.019274 |
| EXOC6B | exocyst complex component 6B | 0.0191388 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0190354 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0185597 |
| SSH2 | slingshot protein phosphatase 2 | 0.0184783 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0184028 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.0183602 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 0.0183536 |
| RAD51B | RAD51 paralog B | 0.0183463 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0181385 |
| FLNB | filamin B, beta | 0.0180994 |
| TBC1D12 | TBC1 domain family, member 12 | 0.0174576 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0173743 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0171602 |
| RHOA | ras homolog family member A | 0.0169828 |
| AMBRA1 | autophagy/beclin-1 regulator 1 | 0.0169674 |
| SCFD2 | sec1 family domain containing 2 | 0.0168506 |
| TMSB10 | thymosin beta 10 | 0.0165934 |
| FOXO3 | forkhead box O3 | 0.0165537 |
| KIDINS220 | kinase D-interacting substrate, 220kDa | 0.016504 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0164975 |
| FOXO1 | forkhead box O1 | 0.0162988 |
| TCN2 | transcobalamin II | 0.0162943 |
| RAB10 | RAB10, member RAS oncogene family | 0.0156073 |
| GSE1 | Gse1 coiled-coil protein | 0.0155092 |
| DST | dystonin | 0.0155016 |
| STK24 | serine/threonine kinase 24 | 0.0154065 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0154044 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0153917 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) | 0.0153072 |
| ATXN2 | ataxin 2 | 0.0151841 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.015156 |
| TAOK3 | TAO kinase 3 | 0.01507 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0149618 |
| B2M | beta-2-microglobulin | 0.0148382 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0148201 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.014767 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0147309 |
| PCDH9 | protocadherin 9 | 0.0147264 |
| RCOR1 | REST corepressor 1 | 0.0142543 |
| FGF12 | fibroblast growth factor 12 | 0.0142503 |
| HIP1 | huntingtin interacting protein 1 | 0.0142295 |
| RPL31 | ribosomal protein L31 | 0.0141114 |
| BZW2 | basic leucine zipper and W2 domains 2 | 0.0140931 |
| CS | citrate synthase | 0.0140759 |
| NTM | neurotrimin | 0.0140604 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0139262 |
| SFPQ | splicing factor proline/glutamine-rich | 0.013881 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0138773 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0138603 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.0138307 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | 0.0137349 |
| CCNYL1 | cyclin Y-like 1 | 0.0137326 |
| APOE | apolipoprotein E | 0.0136768 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0136521 |
| HDGF | hepatoma-derived growth factor | 0.013571 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0135624 |
| AAMDC | adipogenesis associated, Mth938 domain containing | 0.0134818 |
| CORO1C | coronin, actin binding protein, 1C | 0.0134129 |
| PPHLN1 | periphilin 1 | 0.0134012 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0133148 |
| FRMD5 | FERM domain containing 5 | 0.013238 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0132253 |
| CCN2 | cellular communication network factor 2 | 0.0131632 |
| WDR43 | WD repeat domain 43 | 0.0130808 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0130398 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0130117 |
| USP49 | ubiquitin specific peptidase 49 | 0.0130074 |
| CDC14A | cell division cycle 14A | 0.0129424 |
| FTL | ferritin, light polypeptide | 0.0129142 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.012814 |
| INTS6 | integrator complex subunit 6 | 0.0128055 |
| COMMD1 | copper metabolism (Murr1) domain containing 1 | 0.0127776 |
| TESK2 | testis-specific kinase 2 | 0.0126152 |
| CCDC88A | coiled-coil domain containing 88A | 0.0126099 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.113149 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.111211 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.107988 |
| PEG10 | paternally expressed 10 | -0.0921834 |
| VIM | vimentin | -0.0869381 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0753624 |
| H1-0 | H1.0 linker histone | -0.0744178 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.070459 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0673279 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0651088 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0644929 |
| ZNF292 | zinc finger protein 292 | -0.0579249 |
| GPC3 | glypican 3 | -0.0541909 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.053455 |
| ACTG1 | actin gamma 1 | -0.052912 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.04941 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0490973 |
| YBX1 | Y box binding protein 1 | -0.0477241 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0445329 |
| RPLP1 | ribosomal protein, large, P1 | -0.0430693 |
| ZFR | zinc finger RNA binding protein | -0.0418118 |
| CALR | calreticulin | -0.0409484 |
| THBS1 | thrombospondin 1 | -0.0404127 |
| RBM39 | RNA binding motif protein 39 | -0.0373888 |
| TMSB4X | thymosin beta 4, X-linked | -0.0369059 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0357488 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0338698 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0337346 |
| HDAC9 | histone deacetylase 9 | -0.033182 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.0326045 |
| PDGFC | platelet derived growth factor C | -0.0325818 |
| RYBP | RING1 and YY1 binding protein | -0.031829 |
| RPS6 | ribosomal protein S6 | -0.0318092 |
| CLTC | clathrin, heavy chain (Hc) | -0.0302671 |
| SRP54 | signal recognition particle 54kDa | -0.0299054 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0298649 |
| GOLGA4 | golgin A4 | -0.0286767 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0285696 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0285346 |
| COL5A2 | collagen, type V, alpha 2 | -0.0276898 |
| FBL | fibrillarin | -0.0276234 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0267997 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0267195 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0266098 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.0262235 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0261774 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0255689 |
| NOP58 | NOP58 ribonucleoprotein | -0.0255593 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0253527 |
| OGA | O-GlcNAcase | -0.0252822 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0248804 |
| RPLP0 | ribosomal protein, large, P0 | -0.0243984 |
| SHROOM3 | shroom family member 3 | -0.0242555 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0242206 |
| MEIS2 | Meis homeobox 2 | -0.0242127 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0240022 |
| TFRC | transferrin receptor | -0.0234565 |
| TPR | translocated promoter region, nuclear basket protein | -0.0234438 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0231556 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0226636 |
| HMGB2 | high mobility group box 2 | -0.022587 |
| HMGB1 | high mobility group box 1 | -0.0224624 |
| RPS16 | ribosomal protein S16 | -0.0219 |
| ANXA5 | annexin A5 | -0.0218705 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0216866 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0216775 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0216745 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0216331 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0215743 |
| CENPF | centromere protein F, 350/400kDa | -0.0213406 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0213333 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0212962 |
| LRRN3 | leucine rich repeat neuronal 3 | -0.0211783 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.0211701 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0211428 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0211132 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0208506 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0208298 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0207905 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0206605 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.020596 |
| HMGA1 | high mobility group AT-hook 1 | -0.020566 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.020487 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0203234 |
| JMJD1C | jumonji domain containing 1C | -0.0203206 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0200682 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0197921 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | -0.0196785 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0196478 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0196087 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0195898 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0195176 |
| DMD | dystrophin | -0.0194462 |
| FGFR1OP2 | FGFR1 oncogene partner 2 | -0.0194431 |
| CDC73 | cell division cycle 73 | -0.0191771 |
| SKIC3 | SKI3 subunit of superkiller complex | -0.0191745 |
| ANXA2 | annexin A2 | -0.0190288 |
| DDX27 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 | -0.0190027 |
| RFX7 | regulatory factor X, 7 | -0.0189786 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0189034 |
