| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Panobinostat perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Panobinostat_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB4X | thymosin beta 4, X-linked | 0.087306 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.08145 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0679643 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0646133 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.062775 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0518503 |
| RPL3 | ribosomal protein L3 | 0.0513793 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0466175 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0433848 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0407718 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0391809 |
| TXNRD1 | thioredoxin reductase 1 | 0.036957 |
| NCKAP1 | NCK-associated protein 1 | 0.0340307 |
| FLNB | filamin B, beta | 0.0320783 |
| H1-4 | H1.4 linker histone, cluster member | 0.031696 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | 0.0315825 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0315505 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0313851 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0307109 |
| RPS2 | ribosomal protein S2 | 0.0305081 |
| XPO1 | exportin 1 | 0.0304502 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0303706 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0302889 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0300705 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0300431 |
| ANXA1 | annexin A1 | 0.0298557 |
| ZNF217 | zinc finger protein 217 | 0.0291947 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.028773 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0281317 |
| ZNF608 | zinc finger protein 608 | 0.0279733 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0278662 |
| NUP58 | nucleoporin 58 | 0.0274578 |
| CDC73 | cell division cycle 73 | 0.0273977 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0264121 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0263713 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.0263502 |
| SLMAP | sarcolemma associated protein | 0.0256715 |
| AUTS2 | autism susceptibility candidate 2 | 0.0255162 |
| WAC | WW domain containing adaptor with coiled-coil | 0.025455 |
| AFDN | afadin, adherens junction formation factor | 0.0253616 |
| APP | amyloid beta (A4) precursor protein | 0.0253551 |
| ZNF292 | zinc finger protein 292 | 0.0246393 |
| TPD52 | tumor protein D52 | 0.0243916 |
| QKI | QKI, KH domain containing, RNA binding | 0.0242679 |
| NBAS | neuroblastoma amplified sequence | 0.0240805 |
| RAD21 | RAD21 homolog (S. pombe) | 0.023862 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0232902 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0230843 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0229862 |
| PHF3 | PHD finger protein 3 | 0.0229581 |
| SETD5 | SET domain containing 5 | 0.0224264 |
| CENPF | centromere protein F, 350/400kDa | 0.0222011 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0221517 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0219569 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0218067 |
| NONO | non-POU domain containing, octamer-binding | 0.0216643 |
| AHNAK | AHNAK nucleoprotein | 0.0213749 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.021306 |
| CLTC | clathrin, heavy chain (Hc) | 0.0212709 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0210787 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 0.0210631 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0210147 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0206211 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0203444 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0203214 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0200947 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0200741 |
| AHR | aryl hydrocarbon receptor | 0.0200175 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0199664 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0198165 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0197352 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0196937 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.0196788 |
| SPAG9 | sperm associated antigen 9 | 0.0196736 |
| OGA | O-GlcNAcase | 0.0196153 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0195663 |
| TPR | translocated promoter region, nuclear basket protein | 0.0194903 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.0193646 |
| CRY1 | cryptochrome circadian clock 1 | 0.01921 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0190501 |
| MKI67 | marker of proliferation Ki-67 | 0.0188105 |
| RPS18 | ribosomal protein S18 | 0.0187055 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0185219 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0183742 |
| PGK1 | phosphoglycerate kinase 1 | 0.0183007 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.018278 |
| RYBP | RING1 and YY1 binding protein | 0.0181928 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0180324 |
| EVI5 | ecotropic viral integration site 5 | 0.0178643 |
| CUL3 | cullin 3 | 0.0178022 |
| CORO1C | coronin, actin binding protein, 1C | 0.0177688 |
| MACROD2 | MACRO domain containing 2 | 0.0176037 |
| EMSY | EMSY transcriptional repressor, BRCA2 interacting | 0.0175852 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0175235 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0175029 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0174535 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0174304 |
| SFTPA2 | surfactant protein A2 | 0.0172767 |
| CCNY | cyclin Y | 0.0171986 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0171538 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.261883 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.144717 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.11357 |
| RPL35A | ribosomal protein L35a | -0.0929824 |
| FOXP1 | forkhead box P1 | -0.0913347 |
| PTMA | prothymosin, alpha | -0.0886939 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0884522 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0875694 |
| RPS6 | ribosomal protein S6 | -0.0843085 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0825794 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0797972 |
| RPS8 | ribosomal protein S8 | -0.0752506 |
| RPLP1 | ribosomal protein, large, P1 | -0.072796 |
| ACTG1 | actin gamma 1 | -0.0693113 |
| RPS19 | ribosomal protein S19 | -0.0692356 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0675822 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0653753 |
| EGFR | epidermal growth factor receptor | -0.0630664 |
| PKM | pyruvate kinase, muscle | -0.0624599 |
| VCL | vinculin | -0.0621095 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0615226 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.060356 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0583405 |
| RPS23 | ribosomal protein S23 | -0.0580257 |
| RPLP0 | ribosomal protein, large, P0 | -0.0575435 |
| PFN1 | profilin 1 | -0.0564391 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0542212 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0541628 |
| POTEF | POTE ankyrin domain family, member F | -0.052864 |
| RPL31 | ribosomal protein L31 | -0.0527536 |
| RPL12 | ribosomal protein L12 | -0.0510492 |
| S100A6 | S100 calcium binding protein A6 | -0.0498672 |
| TMSB10 | thymosin beta 10 | -0.0498498 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0474899 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0468163 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0464415 |
| S100A9 | S100 calcium binding protein A9 | -0.0464143 |
| RPL23 | ribosomal protein L23 | -0.0457137 |
| RPL13A | ribosomal protein L13a | -0.0454964 |
| RPS13 | ribosomal protein S13 | -0.0447378 |
| RPL34 | ribosomal protein L34 | -0.0445461 |
| FTL | ferritin, light polypeptide | -0.0441338 |
| RPL19 | ribosomal protein L19 | -0.0439608 |
| RPLP2 | ribosomal protein, large, P2 | -0.0433544 |
| RPL37A | ribosomal protein L37a | -0.0432239 |
| RPL11 | ribosomal protein L11 | -0.0423958 |
| RPS25 | ribosomal protein S25 | -0.0407069 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0398635 |
| NBEA | neurobeachin | -0.0395096 |
| RPL9 | ribosomal protein L9 | -0.0394974 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.03925 |
| PRDX2 | peroxiredoxin 2 | -0.0390508 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0387006 |
| S100A4 | S100 calcium binding protein A4 | -0.0386956 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0375669 |
| RPL36 | ribosomal protein L36 | -0.0368417 |
| HMGA1 | high mobility group AT-hook 1 | -0.0364325 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0358663 |
| DIAPH2 | diaphanous-related formin 2 | -0.0357018 |
| RPS11 | ribosomal protein S11 | -0.0355049 |
| BMP10 | bone morphogenetic protein 10 | -0.0354438 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | -0.0352837 |
| JMJD1C | jumonji domain containing 1C | -0.0352003 |
| RPL32 | ribosomal protein L32 | -0.0344442 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0343872 |
| DUSP4 | dual specificity phosphatase 4 | -0.0341208 |
| RPS29 | ribosomal protein S29 | -0.0340049 |
| RPL28 | ribosomal protein L28 | -0.0331305 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0329745 |
| BPTF | bromodomain PHD finger transcription factor | -0.0328143 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0319949 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0319176 |
| RBM25 | RNA binding motif protein 25 | -0.0315702 |
| MT2A | metallothionein 2A | -0.0314836 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0312214 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0310993 |
| RPL5 | ribosomal protein L5 | -0.0307057 |
| RPS16 | ribosomal protein S16 | -0.0306254 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0301933 |
| CUX1 | cut-like homeobox 1 | -0.0301719 |
| RPS14 | ribosomal protein S14 | -0.0299154 |
| RPS21 | ribosomal protein S21 | -0.0298971 |
| RPS24 | ribosomal protein S24 | -0.0298938 |
| RPL27A | ribosomal protein L27a | -0.0297951 |
| RPS12 | ribosomal protein S12 | -0.0294108 |
| RPS4X | ribosomal protein S4, X-linked | -0.0287859 |
| EFNA5 | ephrin-A5 | -0.0276218 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0274306 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0273562 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0273442 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0264861 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0263976 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0263125 |
| RPL8 | ribosomal protein L8 | -0.0262148 |
| S100A10 | S100 calcium binding protein A10 | -0.0261329 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0260847 |
| GNAS | GNAS complex locus | -0.0259885 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.02591 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.025504 |
| RPS15 | ribosomal protein S15 | -0.025431 |
