| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Panobinostat perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Panobinostat_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.208263 |
| FN1 | fibronectin 1 | 0.155635 |
| VCL | vinculin | 0.154611 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0758193 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0733104 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0680544 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0635809 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0627507 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0626913 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.056977 |
| MKI67 | marker of proliferation Ki-67 | 0.0566953 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0554545 |
| ANLN | anillin, actin binding protein | 0.0504629 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0501387 |
| TXNRD1 | thioredoxin reductase 1 | 0.0439835 |
| SFTPA2 | surfactant protein A2 | 0.0438054 |
| TGFB2 | transforming growth factor, beta 2 | 0.0413349 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.039078 |
| CENPF | centromere protein F, 350/400kDa | 0.0388152 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0385791 |
| SPAG9 | sperm associated antigen 9 | 0.03582 |
| FLNA | filamin A, alpha | 0.0347505 |
| SH3RF2 | SH3 domain containing ring finger 2 | 0.0342098 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0331973 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.033186 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0328411 |
| PALLD | palladin, cytoskeletal associated protein | 0.0311215 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0310796 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0309387 |
| CORO1C | coronin, actin binding protein, 1C | 0.0304162 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0295102 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0294879 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0277447 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0272716 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0266785 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0265586 |
| NONO | non-POU domain containing, octamer-binding | 0.0263651 |
| THBS1 | thrombospondin 1 | 0.0259789 |
| TUSC3 | tumor suppressor candidate 3 | 0.025845 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0255444 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0253809 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0253808 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0252542 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0252067 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.025071 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0248863 |
| DIAPH3 | diaphanous-related formin 3 | 0.0247163 |
| FLNB | filamin B, beta | 0.0246083 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0246067 |
| CNKSR3 | CNKSR family member 3 | 0.0244429 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0240492 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0239482 |
| R3HDM1 | R3H domain containing 1 | 0.0237385 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0231327 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0228804 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0227248 |
| VMP1 | vacuole membrane protein 1 | 0.0226854 |
| PRKCA | protein kinase C, alpha | 0.022678 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0226382 |
| PCNX2 | pecanex 2 | 0.0222396 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0221955 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0221204 |
| ACTN1 | actinin, alpha 1 | 0.0220281 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.021985 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0219561 |
| SBF2 | SET binding factor 2 | 0.0218596 |
| BICC1 | BicC family RNA binding protein 1 | 0.0218345 |
| NRXN3 | neurexin 3 | 0.0218293 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0217571 |
| RSU1 | Ras suppressor protein 1 | 0.021493 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0212907 |
| NABP1 | nucleic acid binding protein 1 | 0.0212384 |
| ENAH | enabled homolog (Drosophila) | 0.0211824 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.021114 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0211032 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0208025 |
| CUL4B | cullin 4B | 0.0207977 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0207791 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0206325 |
| KIAA1958 | KIAA1958 | 0.0205781 |
| ACTN4 | actinin, alpha 4 | 0.0204757 |
| IPO7 | importin 7 | 0.0203254 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0202777 |
| CD44 | CD44 molecule (Indian blood group) | 0.0202037 |
| UBE3D | ubiquitin protein ligase E3D | 0.019981 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0198976 |
| KIF11 | kinesin family member 11 | 0.0198839 |
| SMYD3 | SET and MYND domain containing 3 | 0.0198044 |
| ZNF217 | zinc finger protein 217 | 0.0196607 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0196435 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | 0.0195893 |
| EEA1 | early endosome antigen 1 | 0.0194902 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.019484 |
| TAOK3 | TAO kinase 3 | 0.0191265 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0190718 |
| CCDC88A | coiled-coil domain containing 88A | 0.0189792 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0189679 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.018915 |
| TOX2 | TOX high mobility group box family member 2 | 0.0188685 |
| TMSB10 | thymosin beta 10 | 0.018862 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.183209 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.161191 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.153532 |
| PDE10A | phosphodiesterase 10A | -0.149506 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.123359 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.118906 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.115041 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.111013 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0995048 |
| FRMD4A | FERM domain containing 4A | -0.0972694 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0905764 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0835065 |
| VCAN | versican | -0.08192 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0800103 |
| EGFR | epidermal growth factor receptor | -0.0731403 |
| RAI14 | retinoic acid induced 14 | -0.0711376 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0693669 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0683842 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0664236 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0640428 |
| TNS3 | tensin 3 | -0.0634607 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0626134 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0616591 |
| NDRG1 | N-myc downstream regulated 1 | -0.0602697 |
| CADM1 | cell adhesion molecule 1 | -0.0577597 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.057114 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0556228 |
| MYOF | myoferlin | -0.05523 |
| MMP12 | matrix metallopeptidase 12 | -0.0543543 |
| DIAPH2 | diaphanous-related formin 2 | -0.0541532 |
| ZNF292 | zinc finger protein 292 | -0.0534842 |
| AHNAK | AHNAK nucleoprotein | -0.052333 |
| HLA-E | major histocompatibility complex, class I, E | -0.0516352 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0498818 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0471554 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.046302 |
| RBM39 | RNA binding motif protein 39 | -0.0458898 |
| SQSTM1 | sequestosome 1 | -0.0448928 |
| MT2A | metallothionein 2A | -0.0447478 |
| LDHA | lactate dehydrogenase A | -0.0437817 |
| GNAS | GNAS complex locus | -0.0435472 |
| LOXL2 | lysyl oxidase-like 2 | -0.0421639 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0415265 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0414174 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0411221 |
| HMGA2 | high mobility group AT-hook 2 | -0.0409819 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0403555 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.039687 |
| CDH13 | cadherin 13 | -0.0392493 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0388026 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0383497 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0374152 |
| RNF213 | ring finger protein 213 | -0.0370572 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0365527 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0365223 |
| FMNL2 | formin-like 2 | -0.0359247 |
| IER3 | immediate early response 3 | -0.0356491 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0354911 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0352925 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | -0.0335407 |
| ADM | adrenomedullin | -0.0334921 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0334794 |
| LOX | lysyl oxidase | -0.0329151 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0326408 |
| CANX | calnexin | -0.0319966 |
| INSIG1 | insulin induced gene 1 | -0.0319239 |
| STC1 | stanniocalcin 1 | -0.0314296 |
| NAV2 | neuron navigator 2 | -0.0312128 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0310361 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.030796 |
| VIM | vimentin | -0.0304765 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0302249 |
| BBX | bobby sox homolog (Drosophila) | -0.0301783 |
| KIF13A | kinesin family member 13A | -0.0300816 |
| SNX9 | sorting nexin 9 | -0.0300505 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0299088 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0297084 |
| HLA-A | major histocompatibility complex, class I, A | -0.0295981 |
| MX1 | MX dynamin-like GTPase 1 | -0.0293259 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0293037 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0292892 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0290655 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0287796 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0286818 |
| CLMP | CXADR-like membrane protein | -0.028625 |
| FAM20C | family with sequence similarity 20, member C | -0.0281852 |
| STAG2 | stromal antigen 2 | -0.0277824 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0277238 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0271052 |
| EXOC4 | exocyst complex component 4 | -0.026839 |
| PLSCR1 | phospholipid scramblase 1 | -0.0266303 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0264684 |
| CALR | calreticulin | -0.0264132 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0262874 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0262312 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0259464 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0257479 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0257339 |
| MT1X | metallothionein 1X | -0.0256367 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0255939 |
