| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Panobinostat perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Panobinostat_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.156089 |
| STC1 | stanniocalcin 1 | 0.102652 |
| CD44 | CD44 molecule (Indian blood group) | 0.0635552 |
| EXT1 | exostosin glycosyltransferase 1 | 0.061783 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0607198 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0447626 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0417179 |
| EREG | epiregulin | 0.0411354 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0377232 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0376665 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0348581 |
| SDC4 | syndecan 4 | 0.0337412 |
| ATP13A3 | ATPase type 13A3 | 0.0320467 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0318962 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0285348 |
| MT1X | metallothionein 1X | 0.028525 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0282339 |
| NCAM1 | neural cell adhesion molecule 1 | 0.0282325 |
| ENO1 | enolase 1, (alpha) | 0.0271938 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0249803 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0248199 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | 0.0243626 |
| ARMC9 | armadillo repeat containing 9 | 0.0241349 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0234877 |
| EXOC6B | exocyst complex component 6B | 0.022907 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0224867 |
| PLEC | plectin | 0.0221242 |
| GLIS3 | GLIS family zinc finger 3 | 0.0220045 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0217201 |
| PALLD | palladin, cytoskeletal associated protein | 0.021017 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.0208892 |
| CTSB | cathepsin B | 0.0208163 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0204564 |
| PCNX2 | pecanex 2 | 0.0204183 |
| BICC1 | BicC family RNA binding protein 1 | 0.0195678 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | 0.0194702 |
| NGLY1 | N-glycanase 1 | 0.0194353 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0192981 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0192539 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0190616 |
| SYT1 | synaptotagmin I | 0.0188678 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0187818 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0187812 |
| RNF216 | ring finger protein 216 | 0.0186342 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0183756 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0180307 |
| SMOX | spermine oxidase | 0.0179614 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0177371 |
| ATP6V1A | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A | 0.0174897 |
| DNM3 | dynamin 3 | 0.0172643 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0171825 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | 0.0167836 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0166697 |
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 | 0.0163742 |
| TGFB2 | transforming growth factor, beta 2 | 0.0162183 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0161563 |
| SMAP2 | small ArfGAP2 | 0.0161367 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0160967 |
| CCBE1 | collagen and calcium binding EGF domains 1 | 0.0160732 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0160558 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0159395 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0158661 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 | 0.0156376 |
| STC2 | stanniocalcin 2 | 0.015632 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0155387 |
| SYNJ2 | synaptojanin 2 | 0.0154859 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.0154653 |
| DST | dystonin | 0.0153499 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0153345 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0151676 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0151554 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0151252 |
| RPL12 | ribosomal protein L12 | 0.015091 |
| LYST | lysosomal trafficking regulator | 0.0150842 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.0149316 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0148346 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 | 0.0148154 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0147698 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0147556 |
| TMSB4X | thymosin beta 4, X-linked | 0.0147403 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0146651 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | 0.0146521 |
| IRF1 | interferon regulatory factor 1 | 0.0144936 |
| TOR1AIP2 | torsin A interacting protein 2 | 0.0144179 |
| EVI5 | ecotropic viral integration site 5 | 0.0143393 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0142967 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 0.0142013 |
| LUZP1 | leucine zipper protein 1 | 0.0141306 |
| BRD2 | bromodomain containing 2 | 0.0140618 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0140119 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0139442 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0138715 |
| FOXN3 | forkhead box N3 | 0.0138549 |
| PCNX1 | pecanex 1 | 0.0137502 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0137495 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0136457 |
| SKI | SKI proto-oncogene | 0.0136056 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0135495 |
| RYBP | RING1 and YY1 binding protein | 0.0135332 |
| CABIN1 | calcineurin binding protein 1 | 0.0134198 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.161136 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.12489 |
| TMSB10 | thymosin beta 10 | -0.109942 |
| VIM | vimentin | -0.0882569 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0873477 |
| CDH13 | cadherin 13 | -0.0713106 |
| HLA-B | major histocompatibility complex, class I, B | -0.0681617 |
| LOX | lysyl oxidase | -0.0661096 |
| HMGA2 | high mobility group AT-hook 2 | -0.0642651 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0567656 |
| AHNAK | AHNAK nucleoprotein | -0.0555845 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0554256 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0540963 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0501121 |
| CADM1 | cell adhesion molecule 1 | -0.0477466 |
| LOXL2 | lysyl oxidase-like 2 | -0.0462553 |
| PRSS23 | protease, serine, 23 | -0.0459878 |
| MYOF | myoferlin | -0.0455882 |
| ANXA2 | annexin A2 | -0.0448252 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0431214 |
| VEGFC | vascular endothelial growth factor C | -0.0423017 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0421501 |
| ZNF395 | zinc finger protein 395 | -0.041471 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0411555 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0400919 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0393638 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0387388 |
| RBM39 | RNA binding motif protein 39 | -0.0368961 |
| ZNF292 | zinc finger protein 292 | -0.0368169 |
| MAP1B | microtubule-associated protein 1B | -0.0367163 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0365967 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0365196 |
| NRXN3 | neurexin 3 | -0.0363836 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0360475 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0347128 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0341918 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0339098 |
| B2M | beta-2-microglobulin | -0.0332804 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0330237 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0321857 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0315746 |
| RTN4 | reticulon 4 | -0.0315485 |
| NDRG1 | N-myc downstream regulated 1 | -0.0309515 |
| CALD1 | caldesmon 1 | -0.0305371 |
| COL5A1 | collagen, type V, alpha 1 | -0.0300723 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0298112 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0295873 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.029234 |
| TPM4 | tropomyosin 4 | -0.0291575 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0290519 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0288917 |
| FN1 | fibronectin 1 | -0.0279757 |
| NRP1 | neuropilin 1 | -0.0279672 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0277002 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0273748 |
| OGA | O-GlcNAcase | -0.0270944 |
| MAP4 | microtubule-associated protein 4 | -0.0267609 |
| MEF2A | myocyte enhancer factor 2A | -0.026591 |
| EXOC4 | exocyst complex component 4 | -0.0264977 |
| PMM2 | phosphomannomutase 2 | -0.0264827 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0264162 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0263101 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0260714 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0259549 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.025647 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.025587 |
| COL1A2 | collagen, type I, alpha 2 | -0.0255288 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0254703 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0253967 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0250172 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.024973 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0249538 |
| CDK6 | cyclin-dependent kinase 6 | -0.0249428 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0248522 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0247007 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0244407 |
| POTEF | POTE ankyrin domain family, member F | -0.024338 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0242551 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0238813 |
| RAB2A | RAB2A, member RAS oncogene family | -0.023841 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0237674 |
| RPL35A | ribosomal protein L35a | -0.0236785 |
| HDLBP | high density lipoprotein binding protein | -0.0236511 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0235544 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0234891 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0227066 |
| TAGLN2 | transgelin 2 | -0.022596 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0223103 |
| CANX | calnexin | -0.0219872 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0219774 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0217144 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0214284 |
| GOLGB1 | golgin B1 | -0.0213738 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0213442 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0213296 |
| TNNC1 | troponin C type 1 (slow) | -0.0212845 |
| USP34 | ubiquitin specific peptidase 34 | -0.0211175 |
| RAI14 | retinoic acid induced 14 | -0.0209176 |
| LDHA | lactate dehydrogenase A | -0.0204977 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0202648 |
