| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Panobinostat perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Panobinostat_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0822895 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0620429 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0541665 |
| TXNRD1 | thioredoxin reductase 1 | 0.0540723 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0414935 |
| KIAA1958 | KIAA1958 | 0.0406551 |
| ANLN | anillin, actin binding protein | 0.0384734 |
| NONO | non-POU domain containing, octamer-binding | 0.0370217 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0369983 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0360512 |
| MKI67 | marker of proliferation Ki-67 | 0.0350452 |
| SMYD3 | SET and MYND domain containing 3 | 0.0345331 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0330115 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0324723 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0321574 |
| EFNA5 | ephrin-A5 | 0.0316235 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0310107 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0304746 |
| CALU | calumenin | 0.0287583 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.028593 |
| DST | dystonin | 0.0285533 |
| RAD50 | RAD50 homolog (S. cerevisiae) | 0.0284128 |
| KIAA1328 | KIAA1328 | 0.0282969 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0275393 |
| H1-4 | H1.4 linker histone, cluster member | 0.02735 |
| DIAPH3 | diaphanous-related formin 3 | 0.0272052 |
| CD44 | CD44 molecule (Indian blood group) | 0.0271253 |
| RORA | RAR-related orphan receptor A | 0.0262514 |
| CLTC | clathrin, heavy chain (Hc) | 0.02577 |
| CDK6 | cyclin-dependent kinase 6 | 0.0246199 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0237394 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0236654 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0235954 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | 0.0232211 |
| ZNF670 | zinc finger protein 670 | 0.02316 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0230541 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0229843 |
| SET | SET nuclear proto-oncogene | 0.022593 |
| RANBP17 | RAN binding protein 17 | 0.0220545 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0219325 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0218824 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.0217438 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0216642 |
| TMEM245 | transmembrane protein 245 | 0.0216445 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0215326 |
| PHF3 | PHD finger protein 3 | 0.021337 |
| CNKSR3 | CNKSR family member 3 | 0.0212811 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0212646 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0211963 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.0211679 |
| NSD2 | nuclear receptor binding SET domain protein 2 | 0.0210049 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0207254 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0207201 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0205853 |
| GOLGA4 | golgin A4 | 0.0205223 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0203725 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.019884 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0198665 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.0198387 |
| MSN | moesin | 0.0196658 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0196497 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0196452 |
| H1-2 | H1.2 linker histone, cluster member | 0.0194089 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0193479 |
| AMOTL1 | angiomotin like 1 | 0.019326 |
| ITGA6 | integrin, alpha 6 | 0.0193177 |
| CNOT6 | CCR4-NOT transcription complex, subunit 6 | 0.0191443 |
| FANCI | Fanconi anemia, complementation group I | 0.0190076 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0187403 |
| INCENP | inner centromere protein antigens 135/155kDa | 0.0185054 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0184389 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0183391 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 | 0.0183335 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0181985 |
| DOCK9 | dedicator of cytokinesis 9 | 0.0180427 |
| CENPF | centromere protein F, 350/400kDa | 0.0180165 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0178327 |
| TSPAN5 | tetraspanin 5 | 0.0178048 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0173537 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.0172145 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0171928 |
| NCAM1 | neural cell adhesion molecule 1 | 0.0171666 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0170621 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.017032 |
| CEP250 | centrosomal protein 250kDa | 0.0167706 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0167437 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0167099 |
| RRBP1 | ribosome binding protein 1 | 0.0166738 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0165685 |
| SPECC1 | sperm antigen with calponin homology and coiled-coil domains 1 | 0.0165019 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0164552 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0164543 |
| FSCN1 | fascin actin-bundling protein 1 | 0.0163944 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0163763 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0163491 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0162392 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0162242 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0161345 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 0.0161262 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0159813 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.281198 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0916622 |
| PTMA | prothymosin, alpha | -0.0859601 |
| TMSB10 | thymosin beta 10 | -0.0850645 |
| VIM | vimentin | -0.0720647 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0665898 |
| RBM39 | RNA binding motif protein 39 | -0.0625028 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0587565 |
| RPLP1 | ribosomal protein, large, P1 | -0.0584822 |
| LDHA | lactate dehydrogenase A | -0.0576672 |
| GNAS | GNAS complex locus | -0.0542271 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0511761 |
| RPL35A | ribosomal protein L35a | -0.0468238 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.046063 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0455948 |
| POTEF | POTE ankyrin domain family, member F | -0.0430573 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0425846 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0395234 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0389283 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0387964 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0383574 |
| MT2A | metallothionein 2A | -0.0381409 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0379138 |
| RPS8 | ribosomal protein S8 | -0.0377395 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0362362 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.036022 |
| INTS6 | integrator complex subunit 6 | -0.0353908 |
| RPL36 | ribosomal protein L36 | -0.0353469 |
| EGR1 | early growth response 1 | -0.0352629 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0349581 |
| HMGA2 | high mobility group AT-hook 2 | -0.0349004 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0348337 |
| IER3 | immediate early response 3 | -0.0341044 |
| RPL23 | ribosomal protein L23 | -0.0333303 |
| RPL31 | ribosomal protein L31 | -0.0331578 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0331087 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0324102 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0308075 |
| SCFD1 | sec1 family domain containing 1 | -0.0306789 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0302956 |
| RPL37 | ribosomal protein L37 | -0.0301145 |
| SQSTM1 | sequestosome 1 | -0.0287483 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.028648 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0285519 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0283893 |
| NDRG1 | N-myc downstream regulated 1 | -0.0283859 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0283591 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0282584 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0280272 |
| S100A9 | S100 calcium binding protein A9 | -0.0276574 |
| NF1 | neurofibromin 1 | -0.0273767 |
| BPTF | bromodomain PHD finger transcription factor | -0.0267079 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.026239 |
| PARD3 | par-3 family cell polarity regulator | -0.0261551 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0261525 |
| S100A10 | S100 calcium binding protein A10 | -0.0258941 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0257975 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0253917 |
| FTL | ferritin, light polypeptide | -0.0251624 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0249564 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0249094 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0245574 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0245283 |
| RPS13 | ribosomal protein S13 | -0.0243993 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0243662 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0243285 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0242203 |
| RPS17 | ribosomal protein S17 | -0.0240649 |
| ENO1 | enolase 1, (alpha) | -0.0240171 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0239513 |
| RPS6 | ribosomal protein S6 | -0.0236471 |
| MYOF | myoferlin | -0.0233839 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0228385 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0227051 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0226965 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0226311 |
| PTK2 | protein tyrosine kinase 2 | -0.0226019 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0222428 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0221207 |
| RPL34 | ribosomal protein L34 | -0.0220266 |
| ANKRD12 | ankyrin repeat domain 12 | -0.021907 |
| RPS15 | ribosomal protein S15 | -0.0217442 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0216556 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0216387 |
| ZNF638 | zinc finger protein 638 | -0.0215819 |
| RPS23 | ribosomal protein S23 | -0.0215802 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0215668 |
| ANXA2 | annexin A2 | -0.0213679 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0213563 |
| B2M | beta-2-microglobulin | -0.0212688 |
| RPL27A | ribosomal protein L27a | -0.0211859 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.021014 |
| HLA-B | major histocompatibility complex, class I, B | -0.0208445 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0207834 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0206816 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0206124 |
| RPS25 | ribosomal protein S25 | -0.0205443 |
| ARMH4 | armadillo like helical domain containing 4 | -0.0205183 |
| UBC | ubiquitin C | -0.0203841 |
| ATM | ATM serine/threonine kinase | -0.0203128 |
