| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Panobinostat perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Panobinostat_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SMYD3 | SET and MYND domain containing 3 | 0.0885195 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0791952 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0626033 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.044756 |
| DNM3 | dynamin 3 | 0.0424516 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0419418 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0376668 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0322702 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0316007 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0315498 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0304611 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0303719 |
| EXOC6B | exocyst complex component 6B | 0.0299801 |
| VCL | vinculin | 0.0294807 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0283649 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0283274 |
| GPHN | gephyrin | 0.0278217 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0277236 |
| SRPK2 | SRSF protein kinase 2 | 0.0276231 |
| ENAH | enabled homolog (Drosophila) | 0.0274838 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0273165 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0271747 |
| RANBP17 | RAN binding protein 17 | 0.0269314 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0268274 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0266772 |
| PEG10 | paternally expressed 10 | 0.0237156 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0232909 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0231383 |
| PCNX2 | pecanex 2 | 0.0226198 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.0225032 |
| STK38L | serine/threonine kinase 38 like | 0.0224604 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0224356 |
| TUFT1 | tuftelin 1 | 0.0222858 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0222396 |
| TUSC3 | tumor suppressor candidate 3 | 0.0217114 |
| COG5 | component of oligomeric golgi complex 5 | 0.0216273 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) | 0.0215173 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | 0.0213195 |
| CCDC88A | coiled-coil domain containing 88A | 0.0212942 |
| FRY | furry homolog (Drosophila) | 0.0209732 |
| BAIAP2 | BAI1-associated protein 2 | 0.0203551 |
| TAOK3 | TAO kinase 3 | 0.0200383 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0197231 |
| CORO1C | coronin, actin binding protein, 1C | 0.0194017 |
| TXNRD1 | thioredoxin reductase 1 | 0.0191844 |
| PLEC | plectin | 0.0190562 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0190068 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0188617 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.018859 |
| CFAP299 | cilia and flagella associated protein 299 | 0.0188184 |
| RSU1 | Ras suppressor protein 1 | 0.0187717 |
| TYW1B | tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae) | 0.0186536 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0186461 |
| FRMD5 | FERM domain containing 5 | 0.0186221 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0186006 |
| MIPOL1 | mirror-image polydactyly 1 | 0.0185581 |
| SPAG9 | sperm associated antigen 9 | 0.0180009 |
| SESN3 | sestrin 3 | 0.0179638 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0179478 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0176712 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0175286 |
| FRYL | FRY-like | 0.0174801 |
| OLA1 | Obg-like ATPase 1 | 0.0172037 |
| DPF3 | D4, zinc and double PHD fingers, family 3 | 0.0171783 |
| MRTFA | myocardin related transcription factor A | 0.0169813 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0169729 |
| WDR70 | WD repeat domain 70 | 0.0169309 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0166311 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0165812 |
| FGFR1OP2 | FGFR1 oncogene partner 2 | 0.0165812 |
| GPC5 | glypican 5 | 0.0165332 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0165182 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0164926 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0164758 |
| SCLT1 | sodium channel and clathrin linker 1 | 0.0163928 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0161994 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0161784 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0161597 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0160887 |
| R3HDM1 | R3H domain containing 1 | 0.0160611 |
| EML6 | echinoderm microtubule associated protein like 6 | 0.0160429 |
| CEP128 | centrosomal protein 128kDa | 0.015854 |
| SH3PXD2B | SH3 and PX domains 2B | 0.0158235 |
| NBEA | neurobeachin | 0.0157044 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0156076 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | 0.0155982 |
| CCNYL1 | cyclin Y-like 1 | 0.0153927 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0153003 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 0.0152886 |
| TTLL10 | tubulin tyrosine ligase-like family member 10 | 0.015226 |
| SNX29 | sorting nexin 29 | 0.0151372 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0150951 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0150419 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0148963 |
| MAMLD1 | mastermind-like domain containing 1 | 0.0148901 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | 0.0147977 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 0.0147714 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0147218 |
| AMN1 | antagonist of mitotic exit network 1 homolog (S. cerevisiae) | 0.0146986 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0146602 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.243707 |
| NRG1 | neuregulin 1 | -0.242726 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.203707 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.196581 |
| HMGA2 | high mobility group AT-hook 2 | -0.1881 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.181909 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.109722 |
| ITGA1 | integrin, alpha 1 | -0.108107 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0926396 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0790022 |
| PTMA | prothymosin, alpha | -0.0770634 |
| EFNA5 | ephrin-A5 | -0.0745159 |
| SQSTM1 | sequestosome 1 | -0.0741881 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0715299 |
| GLIS3 | GLIS family zinc finger 3 | -0.0697869 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0696756 |
| RAI14 | retinoic acid induced 14 | -0.0662379 |
| CALR | calreticulin | -0.0646177 |
| CANX | calnexin | -0.064394 |
| NDRG1 | N-myc downstream regulated 1 | -0.0571148 |
| PLIN2 | perilipin 2 | -0.0559439 |
| NRP1 | neuropilin 1 | -0.0555157 |
| ASPH | aspartate beta-hydroxylase | -0.0548653 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0522766 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0518526 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0517493 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0490648 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0486512 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0486231 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.048554 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0484124 |
| STC2 | stanniocalcin 2 | -0.0465468 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0455662 |
| TMEM156 | transmembrane protein 156 | -0.0454932 |
| RUNX2 | runt-related transcription factor 2 | -0.0454613 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0448888 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0447695 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0438428 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0429479 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0412117 |
| TMSB10 | thymosin beta 10 | -0.0407104 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0405775 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0404909 |
| TNS3 | tensin 3 | -0.039736 |
| CD109 | CD109 molecule | -0.0381979 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0379806 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0370492 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0364655 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0363866 |
| HLA-B | major histocompatibility complex, class I, B | -0.0361265 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0347157 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.03466 |
| TMEM165 | transmembrane protein 165 | -0.0340096 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0328347 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0312955 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0310624 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0309012 |
| S100A6 | S100 calcium binding protein A6 | -0.0307876 |
| TMSB4X | thymosin beta 4, X-linked | -0.0303754 |
| GPC6 | glypican 6 | -0.0303463 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.030094 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0300005 |
| RBM39 | RNA binding motif protein 39 | -0.0299164 |
| ENO1 | enolase 1, (alpha) | -0.0297709 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0296152 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0291808 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0277754 |
| B2M | beta-2-microglobulin | -0.0277531 |
| VEGFC | vascular endothelial growth factor C | -0.0276702 |
| COPA | coatomer protein complex, subunit alpha | -0.0272449 |
| VEGFA | vascular endothelial growth factor A | -0.0271983 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0271807 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0269324 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0266103 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0263613 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0258811 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0257201 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0256962 |
| FAM20C | family with sequence similarity 20, member C | -0.0256893 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0256306 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0254328 |
| FTL | ferritin, light polypeptide | -0.0253569 |
| GLUL | glutamate-ammonia ligase | -0.0251308 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0248885 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.024845 |
| MYOF | myoferlin | -0.0246971 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | -0.0246804 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0243453 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0241286 |
| RAB31 | RAB31, member RAS oncogene family | -0.0240381 |
| USP34 | ubiquitin specific peptidase 34 | -0.0239417 |
| UBXN4 | UBX domain protein 4 | -0.0237469 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0235423 |
| PRELID2 | PRELI domain containing 2 | -0.0232332 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0232169 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0230359 |
| HDLBP | high density lipoprotein binding protein | -0.0230343 |
| ETV1 | ets variant 1 | -0.0230268 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0227404 |
| GNAS | GNAS complex locus | -0.0221406 |
