Panuveitis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
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Genes

390 genes co-occuring with the disease Panuveitis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
RBP3 retinol binding protein 3, interstitial 3.018
TNF tumor necrosis factor 2.872
ERAP1 endoplasmic reticulum aminopeptidase 1 2.796
CD4 CD4 molecule 2.685
CRP C-reactive protein, pentraxin-related 2.668
HLA-B major histocompatibility complex, class I, B 2.661
IL17A interleukin 17A 2.656
ERAP2 endoplasmic reticulum aminopeptidase 2 2.649
ACE angiotensin I converting enzyme 2.629
SAG S-antigen; retina and pineal gland (arrestin) 2.599
IL6 interleukin 6 2.592
IFNG interferon, gamma 2.547
IL1B interleukin 1, beta 2.463
IL10 interleukin 10 2.442
CD8A CD8a molecule 2.409
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 2.405
IL23R interleukin 23 receptor 2.397
MRAP melanocortin 2 receptor accessory protein 2.374
NOD2 nucleotide-binding oligomerization domain containing 2 2.333
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 2.318
IL1A interleukin 1, alpha 2.293
IL2 interleukin 2 2.259
HLA-A major histocompatibility complex, class I, A 2.254
IFNA1 interferon, alpha 1 2.184
CXCL8 chemokine (C-X-C motif) ligand 8 2.132
CAPN5 calpain 5 2.106
CCL2 chemokine (C-C motif) ligand 2 2.071
IFNA2 interferon, alpha 2 2.034
PRTN3 proteinase 3 2.02
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 2.014
RCVRN recoverin 2.013
IL4 interleukin 4 1.987
IFNA8 interferon, alpha 8 1.985
IFNA16 interferon, alpha 16 1.984
IFNA5 interferon, alpha 5 1.984
IFNA7 interferon, alpha 7 1.983
IFNA21 interferon, alpha 21 1.983
IFNA4 interferon, alpha 4 1.983
IFNA14 interferon, alpha 14 1.983
IFNA10 interferon, alpha 10 1.983
IFNA6 interferon, alpha 6 1.982
IFNA13 interferon, alpha 13 1.98
IFNA17 interferon, alpha 17 1.979
TLR4 toll-like receptor 4 1.966
ICAM1 intercellular adhesion molecule 1 1.939
C1ORF141 chromosome 1 open reading frame 141 1.939
HLA-C major histocompatibility complex, class I, C 1.938
IL22 interleukin 22 1.934
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.933
ALB albumin 1.921
B2M beta-2-microglobulin 1.914
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 1.899
TGFB1 transforming growth factor, beta 1 1.896
IL18 interleukin 18 1.881
MEFV Mediterranean fever 1.862
IL17F interleukin 17F 1.842
CFH complement factor H 1.834
CD80 CD80 molecule 1.83
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.82
CXCL10 chemokine (C-X-C motif) ligand 10 1.788
FOXP3 forkhead box P3 1.783
RPE65 retinal pigment epithelium-specific protein 65kDa 1.768
ACE2 angiotensin I converting enzyme 2 1.765
CD68 CD68 molecule 1.761
CARD9 caspase recruitment domain family, member 9 1.742
MPO myeloperoxidase 1.739
NLRP3 NLR family, pyrin domain containing 3 1.731
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 1.728
LNPEP leucyl/cystinyl aminopeptidase 1.724
TLR2 toll-like receptor 2 1.724
IL2RA interleukin 2 receptor, alpha 1.719
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.718
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.712
IL1RN interleukin 1 receptor antagonist 1.704
TYR tyrosinase 1.692
IL12RB2 interleukin 12 receptor, beta 2 1.685
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 1.679
CCL5 chemokine (C-C motif) ligand 5 1.677
IL5 interleukin 5 1.675
CD19 CD19 molecule 1.657
PTPRC protein tyrosine phosphatase, receptor type, C 1.652
CD28 CD28 molecule 1.648
IL13 interleukin 13 1.64
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 1.639
TYK2 tyrosine kinase 2 1.638
MYD88 myeloid differentiation primary response 88 1.624
IL1R1 interleukin 1 receptor, type I 1.619
FASLG Fas ligand (TNF superfamily, member 6) 1.611
CFB complement factor B 1.607
MBP myelin basic protein 1.607
CD86 CD86 molecule 1.605
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.604
IFNB1 interferon, beta 1, fibroblast 1.604
LTA lymphotoxin alpha 1.603
TGFB2 transforming growth factor, beta 2 1.601
STAT4 signal transducer and activator of transcription 4 1.595
ANTXR2 anthrax toxin receptor 2 1.594
C3 complement component 3 1.588
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 1.587
KLRC4 killer cell lectin-like receptor subfamily C, member 4 1.587
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 1.586
CD274 CD274 molecule 1.585
MOG myelin oligodendrocyte glycoprotein 1.585
PDCD1 programmed cell death 1 1.577
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 1.574
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.574
MMP9 matrix metallopeptidase 9 1.565
RHO rhodopsin 1.563
MVK mevalonate kinase 1.561
JAK1 Janus kinase 1 1.555
BRAF B-Raf proto-oncogene, serine/threonine kinase 1.55
IL6R interleukin 6 receptor 1.549
IL15 interleukin 15 1.542
S100A12 S100 calcium binding protein A12 1.538
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.537
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.532
SAA1 serum amyloid A1 1.523
CCL3 chemokine (C-C motif) ligand 3 1.523
PMEL premelanosome protein 1.521
SAA2 serum amyloid A2 1.52
POMC proopiomelanocortin 1.514
TBX21 T-box 21 1.511
NCAM1 neural cell adhesion molecule 1 1.506
TLR3 toll-like receptor 3 1.502
INS insulin 1.495
IL23A interleukin 23, alpha subunit p19 1.494
IL17RA interleukin 17 receptor A 1.493
CSF3 colony stimulating factor 3 (granulocyte) 1.489
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 1.486
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 1.484
CCL4 chemokine (C-C motif) ligand 4 1.473
NELFCD negative elongation factor complex member C/D 1.472
VCAM1 vascular cell adhesion molecule 1 1.471
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 1.469
CD40 CD40 molecule, TNF receptor superfamily member 5 1.465
KIF21B kinesin family member 21B 1.463
AIRE autoimmune regulator 1.461
IL7 interleukin 7 1.461
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 1.46
MMP3 matrix metallopeptidase 3 1.46
STAT1 signal transducer and activator of transcription 1, 91kDa 1.456
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 1.45
LTF lactotransferrin 1.445
LOC102723407 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8 1.439
CXCR3 chemokine (C-X-C motif) receptor 3 1.439
CD40LG CD40 ligand 1.438
EYS eyes shut homolog (Drosophila) 1.438
JAK2 Janus kinase 2 1.436
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 1.434
UBAC2 UBA domain containing 2 1.431
RLBP1 retinaldehyde binding protein 1 1.429
HEYL hes-related family bHLH transcription factor with YRPW motif-like 1.421
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 1.421
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.418
CREG1 cellular repressor of E1A-stimulated genes 1 1.412
AIF1 allograft inflammatory factor 1 1.407
CCR2 chemokine (C-C motif) receptor 2 1.406
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 1.404
C4A complement component 4A (Rodgers blood group) 1.397
ACTB actin, beta 1.394
WDR11 WD repeat domain 11 1.389
FN1 fibronectin 1 1.389
IL9 interleukin 9 1.376
DYNLT1 dynein, light chain, Tctex-type 1 1.375
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.366
RS1 retinoschisin 1 1.365
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 1.363
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 1.359
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.356
DHFR2 dihydrofolate reductase 2 1.356
CCL20 chemokine (C-C motif) ligand 20 1.352
SELE selectin E 1.348
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 1.347
IL18R1 interleukin 18 receptor 1 1.345
IL33 interleukin 33 1.343
IL1R2 interleukin 1 receptor, type II 1.342
LACRT lacritin 1.341
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.34
CA1 carbonic anhydrase I 1.331
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 1.324
BEST1 bestrophin 1 1.322
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 1.321
CCR6 chemokine (C-C motif) receptor 6 1.321
CD5 CD5 molecule 1.32
FANCC Fanconi anemia, complementation group C 1.316
CCL11 chemokine (C-C motif) ligand 11 1.314
TLR9 toll-like receptor 9 1.31
CRYBB1 crystallin, beta B1 1.31
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1.307
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.304
PRF1 perforin 1 (pore forming protein) 1.302
IL37 interleukin 37 1.302
DHFR dihydrofolate reductase 1.3
SOCS1 suppressor of cytokine signaling 1 1.3
PLAT plasminogen activator, tissue 1.297
CFHR2 complement factor H-related 2 1.296
SRSF6 serine/arginine-rich splicing factor 6 1.293
KLRB1 killer cell lectin-like receptor subfamily B, member 1 1.291
LACC1 laccase (multicopper oxidoreductase) domain containing 1 1.288
FGF2 fibroblast growth factor 2 (basic) 1.286
CD27 CD27 molecule 1.284
CCRL2 chemokine (C-C motif) receptor-like 2 1.275
BCR breakpoint cluster region 1.272
PXDN peroxidasin 1.272
PXDNL peroxidasin-like 1.269
TJP1 tight junction protein 1 1.269
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 1.267
PDC phosducin 1.267
CCR1 chemokine (C-C motif) receptor 1 1.265
CD46 CD46 molecule, complement regulatory protein 1.263
LY96 lymphocyte antigen 96 1.26
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.26
PSIP1 PC4 and SFRS1 interacting protein 1 1.257
TRIM21 tripartite motif containing 21 1.257
SELL selectin L 1.257
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 1.256
ENO1 enolase 1, (alpha) 1.254
TOR1B torsin family 1, member B (torsin B) 1.252
TIMP1 TIMP metallopeptidase inhibitor 1 1.25
CD1C CD1c molecule 1.248
LPIN2 lipin 2 1.246
ADA2 adenosine deaminase 2 1.244
IRF8 interferon regulatory factor 8 1.244
CXCL9 chemokine (C-X-C motif) ligand 9 1.243
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.242
IL12RB1 interleukin 12 receptor, beta 1 1.241
JAK3 Janus kinase 3 1.241
CD163 CD163 molecule 1.233
RUNX3 runt-related transcription factor 3 1.233
RORC RAR-related orphan receptor C 1.231
F2 coagulation factor II (thrombin) 1.23
CX3CR1 chemokine (C-X3-C motif) receptor 1 1.229
MMP1 matrix metallopeptidase 1 1.228
CD69 CD69 molecule 1.225
CD59 CD59 molecule, complement regulatory protein 1.224
IFNL1 interferon, lambda 1 1.223
NGF nerve growth factor (beta polypeptide) 1.218
CD52 CD52 molecule 1.218
HLA-E major histocompatibility complex, class I, E 1.217
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 1.215
C2 complement component 2 1.213
IL36RN interleukin 36 receptor antagonist 1.203
IL36R interleukin 36 receptor 1.197
VASN vasorin 1.195
TLR7 toll-like receptor 7 1.192
PGF placental growth factor 1.19
CCR7 chemokine (C-C motif) receptor 7 1.186
CD44 CD44 molecule (Indian blood group) 1.18
OCLN occludin 1.175
IL7R interleukin 7 receptor 1.174
OPTC opticin 1.173
CNTF ciliary neurotrophic factor 1.171
CD276 CD276 molecule 1.171
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 1.168
JUN jun proto-oncogene 1.167
PTGFR prostaglandin F receptor (FP) 1.164
TMEM134 transmembrane protein 134 1.162
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 1.161
TAC1 tachykinin, precursor 1 1.16
CA2 carbonic anhydrase II 1.159
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 1.158
FLT1 fms-related tyrosine kinase 1 1.156
EGR2 early growth response 2 1.152
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.152
CNGA3 cyclic nucleotide gated channel alpha 3 1.15
TPO thyroid peroxidase 1.149
CFI complement factor I 1.149
LCN2 lipocalin 2 1.147
HP haptoglobin 1.147
MMP8 matrix metallopeptidase 8 1.147
KDR kinase insert domain receptor 1.144
C5 complement component 5 1.144
FBXO22 F-box protein 22 1.142
C4B complement component 4B (Chido blood group) 1.14
TNRC18 trinucleotide repeat containing 18 1.138
ZMIZ1 zinc finger, MIZ-type containing 1 1.137
TRIM45 tripartite motif containing 45 1.137
CRYGS crystallin, gamma S 1.135
GJB6 gap junction protein, beta 6, 30kDa 1.134
NLRP1 NLR family, pyrin domain containing 1 1.132
IL1F10 interleukin 1 family, member 10 (theta) 1.132
TYRP1 tyrosinase-related protein 1 1.132
SSB Sjogren syndrome antigen B (autoantigen La) 1.13
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.13
IRAK1 interleukin-1 receptor-associated kinase 1 1.125
TLR1 toll-like receptor 1 1.124
IFNAR1 interferon (alpha, beta and omega) receptor 1 1.122
HLA-G major histocompatibility complex, class I, G 1.119
TMPRSS2 transmembrane protease, serine 2 1.118
HMGB1 high mobility group box 1 1.117
RPGR retinitis pigmentosa GTPase regulator 1.114
CNGB3 cyclic nucleotide gated channel beta 3 1.113
S100A9 S100 calcium binding protein A9 1.113
CXCR4 chemokine (C-X-C motif) receptor 4 1.112
MMP2 matrix metallopeptidase 2 1.112
IFIH1 interferon induced with helicase C domain 1 1.111
EGF epidermal growth factor 1.11
SOCS3 suppressor of cytokine signaling 3 1.108
CXCL12 chemokine (C-X-C motif) ligand 12 1.107
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.107
PECAM1 platelet/endothelial cell adhesion molecule 1 1.104
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.104
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.104
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.103
FGF7 fibroblast growth factor 7 1.102
F3 coagulation factor III (thromboplastin, tissue factor) 1.101
EDNRA endothelin receptor type A 1.101
P3H3 prolyl 3-hydroxylase 3 1.101
ELANE elastase, neutrophil expressed 1.1
ARMS2 age-related maculopathy susceptibility 2 1.099
TAPBP TAP binding protein (tapasin) 1.096
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 1.096
CLEC7A C-type lectin domain family 7, member A 1.093
CD2 CD2 molecule 1.089
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 1.087
PLG plasminogen 1.087
IL1RAP interleukin 1 receptor accessory protein 1.085
ADAD1 adenosine deaminase domain containing 1 (testis-specific) 1.084
CD1D CD1d molecule 1.083
CD22 CD22 molecule 1.081
CD200 CD200 molecule 1.08
ANGPT2 angiopoietin 2 1.079
IL27 interleukin 27 1.077
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta 1.075
HRH2 histamine receptor H2 1.075
MME membrane metallo-endopeptidase 1.072
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 1.071
PFDN5 prefoldin subunit 5 1.069
CXCL13 chemokine (C-X-C motif) ligand 13 1.069
CD1B CD1b molecule 1.067
KLRD1 killer cell lectin-like receptor subfamily D, member 1 1.067
CD1E CD1e molecule 1.067
TOR1A torsin family 1, member A (torsin A) 1.066
GPR25 G protein-coupled receptor 25 1.066
IL31 interleukin 31 1.066
H2BC21 H2B clustered histone 21 1.065
GPR35 G protein-coupled receptor 35 1.063
KIFAP3 kinesin-associated protein 3 1.061
TECPR2 tectonin beta-propeller repeat containing 2 1.06
IL26 interleukin 26 1.06
REN renin 1.06
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 1.058
IL17RC interleukin 17 receptor C 1.058
CD1A CD1a molecule 1.056
NLRC4 NLR family, CARD domain containing 4 1.053
INAVA innate immunity activator 1.052
NLRP12 NLR family, pyrin domain containing 12 1.048
HSPA4 heat shock 70kDa protein 4 1.047
CISH cytokine inducible SH2-containing protein 1.046
CD200R1 CD200 receptor 1 1.045
ORM1 orosomucoid 1 1.042
HMOX1 heme oxygenase 1 1.038
FGF5 fibroblast growth factor 5 1.034
FGF4 fibroblast growth factor 4 1.031
FGF22 fibroblast growth factor 22 1.031
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 1.03
FGF16 fibroblast growth factor 16 1.03
FGF3 fibroblast growth factor 3 1.029
FGF6 fibroblast growth factor 6 1.029
FGF20 fibroblast growth factor 20 1.027
CXCR5 chemokine (C-X-C motif) receptor 5 1.027
NPEPPS aminopeptidase puromycin sensitive 1.026
BTNL2 butyrophilin-like 2 1.026
CKB creatine kinase, brain 1.025
FGF17 fibroblast growth factor 17 1.025
FGF9 fibroblast growth factor 9 1.024
IL2RB interleukin 2 receptor, beta 1.021
SDC1 syndecan 1 1.021
FGF18 fibroblast growth factor 18 1.021
NOS2 nitric oxide synthase 2, inducible 1.021
ACKR2 atypical chemokine receptor 2 1.019
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 1.018
CKMT1B creatine kinase, mitochondrial 1B 1.017
SLC4A11 solute carrier family 4, sodium borate transporter, member 11 1.016
BCL2 B-cell CLL/lymphoma 2 1.016
IL3 interleukin 3 1.015
FGF10 fibroblast growth factor 10 1.014
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 1.014
KRT12 keratin 12, type I 1.013
CARD14 caspase recruitment domain family, member 14 1.013
CKM creatine kinase, muscle 1.013
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae) 1.01
THBS1 thrombospondin 1 1.01
TRAF3IP2 TRAF3 interacting protein 2 1.01
FGF8 fibroblast growth factor 8 (androgen-induced) 1.006
ERVW-1 endogenous retrovirus group W, member 1 1.004
TEK TEK tyrosine kinase, endothelial 1.003
ORM2 orosomucoid 2 1.003
TTR transthyretin 1.002
TLR5 toll-like receptor 5 1.0