Papilledema Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D010211
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Genes

213 genes/proteins associated with the disease Papilledema from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.0826
TNF tumor necrosis factor 2.04967
IL6 interleukin 6 1.91928
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.78873
CAT catalase 1.75321
IL1B interleukin 1, beta 1.75003
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.74281
GSTP1 glutathione S-transferase pi 1 1.71728
IFNG interferon, gamma 1.68295
BAX BCL2-associated X protein 1.6662
CXCL8 chemokine (C-X-C motif) ligand 8 1.64955
TAGLN transgelin 1.64708
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.63361
FAS Fas cell surface death receptor 1.63205
KRT8 keratin 8, type II 1.58959
BCL2 B-cell CLL/lymphoma 2 1.53357
IL2 interleukin 2 1.52693
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.49226
IL4 interleukin 4 1.49174
MMP2 matrix metallopeptidase 2 1.49174
CCL2 chemokine (C-C motif) ligand 2 1.47813
PLG plasminogen 1.46488
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.46409
MMP13 matrix metallopeptidase 13 1.44872
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.44572
LCN2 lipocalin 2 1.44056
PRL prolactin 1.43212
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.42859
TP53 tumor protein p53 1.4202
MPO myeloperoxidase 1.41035
F2 coagulation factor II (thrombin) 1.4076
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.40373
MMP9 matrix metallopeptidase 9 1.3998
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.39869
PLTP phospholipid transfer protein 1.39841
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.39646
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.39394
FDFT1 farnesyl-diphosphate farnesyltransferase 1 1.3903
EGFR epidermal growth factor receptor 1.38752
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.37047
NDRG2 NDRG family member 2 1.3639
GJA1 gap junction protein, alpha 1, 43kDa 1.36076
CLU clusterin 1.35849
THBS1 thrombospondin 1 1.35792
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.35647
VEGFA vascular endothelial growth factor A 1.35098
CCNG1 cyclin G1 1.34897
VCAM1 vascular cell adhesion molecule 1 1.34314
SOD2 superoxide dismutase 2, mitochondrial 1.34082
BCL2L1 BCL2-like 1 1.3388
COL3A1 collagen, type III, alpha 1 1.33346
APP amyloid beta (A4) precursor protein 1.32607
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.32488
MMP3 matrix metallopeptidase 3 1.29533
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 1.29379
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.29133
ALB albumin 1.29011
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.28919
DDIT3 DNA-damage-inducible transcript 3 1.28889
FOS FBJ murine osteosarcoma viral oncogene homolog 1.28796
FADS2 fatty acid desaturase 2 1.28672
NCOA1 nuclear receptor coactivator 1 1.28241
NQO1 NAD(P)H dehydrogenase, quinone 1 1.28119
FMO1 flavin containing monooxygenase 1 1.26083
ALAS1 5'-aminolevulinate synthase 1 1.25682
SPP1 secreted phosphoprotein 1 1.25651
CTSL cathepsin L 1.25276
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.25214
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.24843
JUN jun proto-oncogene 1.2437
IGFBP5 insulin-like growth factor binding protein 5 1.24307
GADD45A growth arrest and DNA-damage-inducible, alpha 1.24181
S100A9 S100 calcium binding protein A9 1.24118
CCND1 cyclin D1 1.23899
HTRA1 HtrA serine peptidase 1 1.23552
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.2352
APOE apolipoprotein E 1.23392
HBEGF heparin-binding EGF-like growth factor 1.2336
PARP1 poly (ADP-ribose) polymerase 1 1.22948
COL1A1 collagen, type I, alpha 1 1.22469
MCL1 myeloid cell leukemia 1 1.22274
HMOX1 heme oxygenase 1 1.22177
ATF5 activating transcription factor 5 1.21984
EPO erythropoietin 1.21887
IL10 interleukin 10 1.21727
ARNT aryl hydrocarbon receptor nuclear translocator 1.21534
DNASE1 deoxyribonuclease I 1.21271
ICAM1 intercellular adhesion molecule 1 1.20816
MAP2K2 mitogen-activated protein kinase kinase 2 1.20622
CFLAR CASP8 and FADD-like apoptosis regulator 1.20295
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.20262
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 1.20229
PER1 period circadian clock 1 1.19933
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.19279
RGS4 regulator of G-protein signaling 4 1.19113
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.1862
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 1.1862
PTGDS prostaglandin D2 synthase 21kDa (brain) 1.18587
CCL3 chemokine (C-C motif) ligand 3 1.18489
LIPC lipase, hepatic 1.18326
NUPR1 nuclear protein, transcriptional regulator, 1 1.17993
RXRG retinoid X receptor, gamma 1.1753
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.16866
FN1 fibronectin 1 1.16866
ATF3 activating transcription factor 3 1.16866
MAPK14 mitogen-activated protein kinase 14 1.16766
FOSL2 FOS-like antigen 2 1.16766
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 1.16434
C3 complement component 3 1.16302
SOCS2 suppressor of cytokine signaling 2 1.16302
TGFB1 transforming growth factor, beta 1 1.16236
TF transferrin 1.16137
CD44 CD44 molecule (Indian blood group) 1.16001
GJB1 gap junction protein, beta 1, 32kDa 1.15797
NOS3 nitric oxide synthase 3 (endothelial cell) 1.15492
JAK1 Janus kinase 1 1.15089
GPX1 glutathione peroxidase 1 1.15055
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.15055
CXCL12 chemokine (C-X-C motif) ligand 12 1.14816
POMC proopiomelanocortin 1.14747
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.14473
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 1.14166
GSR glutathione reductase 1.1403
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 1.13484
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.13484
CKB creatine kinase, brain 1.13075
IGFBP3 insulin-like growth factor binding protein 3 1.12872
PECR peroxisomal trans-2-enoyl-CoA reductase 1.12703
APOA4 apolipoprotein A-IV 1.12634
FOXO1 forkhead box O1 1.12634
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.12461
NOX4 NADPH oxidase 4 1.12014
HPN hepsin 1.11945
MSMO1 methylsterol monooxygenase 1 1.11809
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 1.11396
PCDH7 protocadherin 7 1.11151
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.11081
F2R coagulation factor II (thrombin) receptor 1.10596
CTGF connective tissue growth factor 1.10527
ISYNA1 inositol-3-phosphate synthase 1 1.10424
FKBP5 FK506 binding protein 5 1.10175
IRF9 interferon regulatory factor 9 1.10069
ADORA3 adenosine A3 receptor 1.10069
PLAT plasminogen activator, tissue 1.09892
IL5 interleukin 5 1.09892
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 1.09786
G6PD glucose-6-phosphate dehydrogenase 1.09751
RAB31 RAB31, member RAS oncogene family 1.09716
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.09646
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.09611
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 1.09576
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.09436
LOX lysyl oxidase 1.09011
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.08762
CLCN4 chloride channel, voltage-sensitive 4 1.08584
CES2 carboxylesterase 2 1.08478
TOB1 transducer of ERBB2, 1 1.08337
NR2F1 nuclear receptor subfamily 2, group F, member 1 1.08337
CYCS cytochrome c, somatic 1.08337
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.08196
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.08196
GUCY1B3 guanylate cyclase 1, soluble, beta 3 1.08019
C10ORF10 chromosome 10 open reading frame 10 1.08019
PDGFB platelet-derived growth factor beta polypeptide 1.07732
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.07696
ITGB5 integrin, beta 5 1.07696
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.07518
ODC1 ornithine decarboxylase 1 1.07482
TEX261 testis expressed 261 1.07234
S100A8 S100 calcium binding protein A8 1.07022
GEM GTP binding protein overexpressed in skeletal muscle 1.06734
LCK LCK proto-oncogene, Src family tyrosine kinase 1.06734
SLC39A8 solute carrier family 39 (zinc transporter), member 8 1.06734
BBC3 BCL2 binding component 3 1.06479
GTPBP1 GTP binding protein 1 1.06406
ZFP36L1 ZFP36 ring finger protein-like 1 1.06116
POR P450 (cytochrome) oxidoreductase 1.06008
TGFA transforming growth factor, alpha 1.05972
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 1.05864
RUNX1 runt-related transcription factor 1 1.05793
HMHA1 histocompatibility (minor) HA-1 1.05721
MUC1 mucin 1, cell surface associated 1.05535
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.05461
COL6A3 collagen, type VI, alpha 3 1.05237
LYN LYN proto-oncogene, Src family tyrosine kinase 1.052
BID BH3 interacting domain death agonist 1.05126
AIF1L allograft inflammatory factor 1-like 1.05089
SLCO4C1 solute carrier organic anion transporter family, member 4C1 1.05052
GSTA2 glutathione S-transferase alpha 2 1.04389
AR androgen receptor 1.04163
ALCAM activated leukocyte cell adhesion molecule 1.04051
LPIN1 lipin 1 1.04014
PPARA peroxisome proliferator-activated receptor alpha 1.03976
EDNRB endothelin receptor type B 1.03939
BRCA1 breast cancer 1, early onset 1.03789
DUSP4 dual specificity phosphatase 4 1.03752
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.03752
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 1.03752
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 1.03641
ALOX5AP arachidonate 5-lipoxygenase-activating protein 1.02933
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 1.02671
F3 coagulation factor III (thromboplastin, tissue factor) 1.02522
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) 1.0241
ERBB2 erb-b2 receptor tyrosine kinase 2 1.02225
NKX2-1 NK2 homeobox 1 1.02151
HDC histidine decarboxylase 1.0189
BTG2 BTG family, member 2 1.01776
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.01776
SDC4 syndecan 4 1.01663
ATF4 activating transcription factor 4 1.01625
ANXA4 annexin A4 1.01361
UGCG UDP-glucose ceramide glucosyltransferase 1.01361
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 1.01099