Paracoccidioidomycosis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A primary systemic mycosis that results_in systemic fungal infection located_in mucosa, located_in lymph nodes, located_in bone, located_in skin or located_in lungs, has_material_basis_in Paracoccidioides brasiliensis. (Human Disease Ontology, DOID_12662)
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Genes

165 genes co-occuring with the disease Paracoccidioidomycosis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
CLEC7A C-type lectin domain family 7, member A 2.626
IFNG interferon, gamma 2.485
IL10 interleukin 10 2.378
EMB embigin 2.331
CD4 CD4 molecule 2.285
TNF tumor necrosis factor 2.203
IL4 interleukin 4 2.199
CLEC6A C-type lectin domain family 6, member A 2.148
TLR2 toll-like receptor 2 2.066
IL17A interleukin 17A 2.047
IL12RB1 interleukin 12 receptor, beta 1 2.042
CARD9 caspase recruitment domain family, member 9 1.941
CD8A CD8a molecule 1.898
TLR4 toll-like receptor 4 1.898
IL1B interleukin 1, beta 1.842
TGFB1 transforming growth factor, beta 1 1.839
IL6 interleukin 6 1.839
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.835
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.831
IL5 interleukin 5 1.82
IFNGR1 interferon gamma receptor 1 1.818
CD209 CD209 molecule 1.773
IL2 interleukin 2 1.733
TPI1 triosephosphate isomerase 1 1.711
CLYBL citrate lyase beta like 1.698
IL22 interleukin 22 1.649
MYD88 myeloid differentiation primary response 88 1.625
FN1 fibronectin 1 1.62
CLEC4E C-type lectin domain family 4, member E 1.617
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1 1.612
CLEC4D C-type lectin domain family 4, member D 1.605
FOXP3 forkhead box P3 1.589
CD86 CD86 molecule 1.577
IDO1 indoleamine 2,3-dioxygenase 1 1.571
SYK spleen tyrosine kinase 1.568
RABAC1 Rab acceptor 1 (prenylated) 1.548
PLB1 phospholipase B1 1.541
TLR9 toll-like receptor 9 1.539
ALB albumin 1.531
IL18 interleukin 18 1.525
HSPA4 heat shock 70kDa protein 4 1.522
IL17RA interleukin 17 receptor A 1.497
IL1A interleukin 1, alpha 1.491
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 1.468
GABPB2 GA binding protein transcription factor, beta subunit 2 1.468
CABP1 calcium binding protein 1 1.467
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.457
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 1.454
STAT1 signal transducer and activator of transcription 1, 91kDa 1.441
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 1.44
IL13 interleukin 13 1.435
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.43
NLRP3 NLR family, pyrin domain containing 3 1.429
CD80 CD80 molecule 1.421
RORC RAR-related orphan receptor C 1.407
CD207 CD207 molecule, langerin 1.4
CCL3 chemokine (C-C motif) ligand 3 1.398
IL17F interleukin 17F 1.394
THNSL2 threonine synthase-like 2 (S. cerevisiae) 1.386
POMC proopiomelanocortin 1.38
PLG plasminogen 1.379
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1.377
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 1.358
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.356
NELFCD negative elongation factor complex member C/D 1.354
CXCL8 chemokine (C-X-C motif) ligand 8 1.35
CD40 CD40 molecule, TNF receptor superfamily member 5 1.328
IL15 interleukin 15 1.323
LGALS3 lectin, galactoside-binding, soluble, 3 1.312
IL9 interleukin 9 1.309
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 1.304
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 1.288
IL17RC interleukin 17 receptor C 1.279
CD40LG CD40 ligand 1.271
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.27
PWP2 PWP2 periodic tryptophan protein homolog (yeast) 1.268
RPAP1 RNA polymerase II associated protein 1 1.254
HPD 4-hydroxyphenylpyruvate dioxygenase 1.25
CXCL9 chemokine (C-X-C motif) ligand 9 1.243
TLR1 toll-like receptor 1 1.241
NOS2 nitric oxide synthase 2, inducible 1.22
C4B complement component 4B (Chido blood group) 1.219
TBX21 T-box 21 1.214
TYRP1 tyrosinase-related protein 1 1.214
PRF1 perforin 1 (pore forming protein) 1.213
DPH6 diphthamine biosynthesis 6 1.209
FGB fibrinogen beta chain 1.206
TLR7 toll-like receptor 7 1.2
C4A complement component 4A (Rodgers blood group) 1.199
ARG1 arginase 1 1.198
AMN1 antagonist of mitotic exit network 1 homolog (S. cerevisiae) 1.194
GATA2 GATA binding protein 2 1.184
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 1.181
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.174
PXDNL peroxidasin-like 1.173
KLK15 kallikrein-related peptidase 15 1.173
PXDN peroxidasin 1.171
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 1.167
R3HCC1L R3H domain and coiled-coil containing 1-like 1.165
CALML4 calmodulin-like 4 1.164
CALML6 calmodulin-like 6 1.164
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 1.164
CALML3 calmodulin-like 3 1.162
CALML5 calmodulin-like 5 1.161
CGA glycoprotein hormones, alpha polypeptide 1.157
CXCL10 chemokine (C-X-C motif) ligand 10 1.149
GPR85 G protein-coupled receptor 85 1.148
IFNB1 interferon, beta 1, fibroblast 1.142
ACO2 aconitase 2, mitochondrial 1.14
CD28 CD28 molecule 1.135
IL33 interleukin 33 1.129
TUB tubby bipartite transcription factor 1.126
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 1.124
LOC112694756 uncharaterized LOC112694756 1.122
CD69 CD69 molecule 1.12
ENO4 enolase family member 4 1.115
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 1.114
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.108
CCL5 chemokine (C-C motif) ligand 5 1.103
IDO2 indoleamine 2,3-dioxygenase 2 1.103
DYNLT1 dynein, light chain, Tctex-type 1 1.102
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.101
TLR3 toll-like receptor 3 1.1
GATA3 GATA binding protein 3 1.1
FASLG Fas ligand (TNF superfamily, member 6) 1.1
CRP C-reactive protein, pentraxin-related 1.096
IK IK cytokine, down-regulator of HLA II 1.09
SELL selectin L 1.089
FBXO3 F-box protein 3 1.089
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.088
CIR1 corepressor interacting with RBPJ, 1 1.085
RBPMS2 RNA binding protein with multiple splicing 2 1.085
MBL2 mannose-binding lectin (protein C) 2, soluble 1.083
CHIT1 chitinase 1 (chitotriosidase) 1.082
TLR6 toll-like receptor 6 1.081
CCL11 chemokine (C-C motif) ligand 11 1.08
H1-8 H1.8 linker histone 1.079
TXN thioredoxin 1.079
OGA O-GlcNAcase 1.076
ICAM3 intercellular adhesion molecule 3 1.072
IL12RB2 interleukin 12 receptor, beta 2 1.063
GPHA2 glycoprotein hormone alpha 2 1.063
FIBCD1 fibrinogen C domain containing 1 1.061
SOD3 superoxide dismutase 3, extracellular 1.058
AHR aryl hydrocarbon receptor 1.056
AIRE autoimmune regulator 1.055
DOCK8 dedicator of cytokinesis 8 1.047
CCL2 chemokine (C-C motif) ligand 2 1.044
CDR2 cerebellar degeneration-related protein 2, 62kDa 1.043
PRB2 proline-rich protein BstNI subfamily 2 1.042
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.034
ACO1 aconitase 1, soluble 1.031
CRHR1 corticotropin releasing hormone receptor 1 1.031
GNLY granulysin 1.03
BCL10 B-cell CLL/lymphoma 10 1.028
LTF lactotransferrin 1.028
CCL4 chemokine (C-C motif) ligand 4 1.027
C3 complement component 3 1.02
CD1D CD1d molecule 1.02
CCR7 chemokine (C-C motif) receptor 7 1.019
MSMO1 methylsterol monooxygenase 1 1.011
TBL1X transducin (beta)-like 1X-linked 1.011
ZNF341 zinc finger protein 341 1.005
IL1R1 interleukin 1 receptor, type I 1.004
LMLN leishmanolysin-like (metallopeptidase M8 family) 1.002