Parakeratosis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Abnormal formation of the keratinocytes of the epidermis characterized by persistence of nuclei, incomplete formation of keratin, and moistness and swelling of the keratinocytes. (Human Phenotype Ontology, HP_0001036)
External Link https://www.disgenet.org/browser/0/1/0/C0030436
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Genes

31 genes associated with the disease Parakeratosis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
CARD14 caspase recruitment domain family, member 14
CLDN1 claudin 1
CYP4F22 cytochrome P450, family 4, subfamily F, polypeptide 22
DNASE1L2 deoxyribonuclease I-like 2
DNASE2 deoxyribonuclease II, lysosomal
DSP desmoplakin
ENO1 enolase 1, (alpha)
FLG2 filaggrin family member 2
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IL17A interleukin 17A
IL23A interleukin 23, alpha subunit p19
IL36RN interleukin 36 receptor antagonist
KRT14 keratin 14, type I
LCN2 lipocalin 2
LOR loricrin
MBTPS2 membrane-bound transcription factor peptidase, site 2
MVD mevalonate (diphospho) decarboxylase
MVK mevalonate kinase
NIPAL4 NIPA-like domain containing 4
NLRP1 NLR family, pyrin domain containing 1
NSDHL NAD(P) dependent steroid dehydrogenase-like
PMVK phosphomevalonate kinase
POMP proteasome maturation protein
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
SPINK5 serine peptidase inhibitor, Kazal type 5
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TGM1 transglutaminase 1
TNC tenascin C
TREX2 three prime repair exonuclease 2
TRPV3 transient receptor potential cation channel, subfamily V, member 3