Parkinson's Disease_Substantia Nigra_GSE7621 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE7621
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Genes

600 genes differentially expressed during Parkinson's Disease_Substantia Nigra_GSE7621 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 3.39336
WIPI2 WD repeat domain, phosphoinositide interacting 2 2.89765
RAD23A RAD23 homolog A (S. cerevisiae) 2.71276
SLC35E1 solute carrier family 35, member E1 2.54233
OCIAD1 OCIA domain containing 1 2.49935
MTDH metadherin 2.45738
TMEM214 transmembrane protein 214 2.42154
TXNDC17 thioredoxin domain containing 17 2.2799
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 2.27031
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 2.2401
SECISBP2 SECIS binding protein 2 2.2381
KRTCAP2 keratinocyte associated protein 2 2.22581
PRKCI protein kinase C, iota 2.22265
ERCC1 excision repair cross-complementation group 1 2.21718
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 2.20491
RPAIN RPA interacting protein 2.18197
NOSIP nitric oxide synthase interacting protein 2.1532
MAF1 MAF1 homolog (S. cerevisiae) 2.149
NCAPD2 non-SMC condensin I complex, subunit D2 2.10702
GPS2 G protein pathway suppressor 2 2.10227
GRB2 growth factor receptor-bound protein 2 2.10189
CTCF CCCTC-binding factor (zinc finger protein) 2.08923
ARMC8 armadillo repeat containing 8 2.05847
MRPL45 mitochondrial ribosomal protein L45 2.04015
RHEB Ras homolog enriched in brain 2.03111
ZCCHC2 zinc finger, CCHC domain containing 2 1.99431
ZDHHC16 zinc finger, DHHC-type containing 16 1.98917
TPPP tubulin polymerization promoting protein 1.96608
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa 1.96505
CSNK1A1 casein kinase 1, alpha 1 1.95899
TMEM19 transmembrane protein 19 1.95818
USP48 ubiquitin specific peptidase 48 1.95757
TRIM27 tripartite motif containing 27 1.95719
LRRC23 leucine rich repeat containing 23 1.95362
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 1.937
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 1.93492
MRFAP1 Morf4 family associated protein 1 1.93357
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 1.93274
SSR1 signal sequence receptor, alpha 1.92078
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 1.92063
UBL3 ubiquitin-like 3 1.9101
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 1.907
TMEM248 transmembrane protein 248 1.88982
TOR1B torsin family 1, member B (torsin B) 1.88203
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 1.87201
HIGD2A HIG1 hypoxia inducible domain family, member 2A 1.86969
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 1.86541
OXSR1 oxidative stress responsive 1 1.86169
ZRANB2 zinc finger, RAN-binding domain containing 2 1.85524
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD) 1.85452
CCDC12 coiled-coil domain containing 12 1.85307
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 1.85
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase 1.84297
UBXN1 UBX domain protein 1 1.83673
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase 1.8282
BIN3 bridging integrator 3 1.82296
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 1.81891
PIH1D1 PIH1 domain containing 1 1.8139
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.81276
SF3A3 splicing factor 3a, subunit 3, 60kDa 1.81187
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit 1.80632
VKORC1 vitamin K epoxide reductase complex, subunit 1 1.8024
C11ORF71 chromosome 11 open reading frame 71 1.79492
PARP3 poly (ADP-ribose) polymerase family, member 3 1.79139
FCHSD2 FCH and double SH3 domains 2 1.79041
KPNB1 karyopherin (importin) beta 1 1.78502
ARMC1 armadillo repeat containing 1 1.77229
SFSWAP splicing factor, suppressor of white-apricot family 1.77221
NEK11 NIMA-related kinase 11 1.77142
FAM122A family with sequence similarity 122A 1.76695
DCP1B decapping mRNA 1B 1.76171
MOB2 MOB kinase activator 2 1.75645
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) 1.75401
MSH6 mutS homolog 6 1.75388
GLG1 golgi glycoprotein 1 1.75109
MYO1E myosin IE 1.74995
GGPS1 geranylgeranyl diphosphate synthase 1 1.74892
POLR3GL polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like 1.74766
CTBP1 C-terminal binding protein 1 1.74298
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 1.73543
COX5B cytochrome c oxidase subunit Vb 1.72425
CFL1 cofilin 1 (non-muscle) 1.7227
RAB11FIP2 RAB11 family interacting protein 2 (class I) 1.71475
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 1.70265
GAS6 growth arrest-specific 6 1.69969
FITM2 fat storage-inducing transmembrane protein 2 1.69944
CTSD cathepsin D 1.69774
COX17 COX17 cytochrome c oxidase copper chaperone 1.69698
LEPROTL1 leptin receptor overlapping transcript-like 1 1.6953
MUT methylmalonyl CoA mutase 1.69527
TMEM132A transmembrane protein 132A 1.6901
FHDC1 FH2 domain containing 1 1.68795
TM9SF4 transmembrane 9 superfamily protein member 4 1.6873
TMEM192 transmembrane protein 192 1.68429
SCNM1 sodium channel modifier 1 1.68272
ATXN1 ataxin 1 1.67964
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) 1.67748
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24 1.66617
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 1.66363
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 1.65777
CDK17 cyclin-dependent kinase 17 1.65414
CCDC69 coiled-coil domain containing 69 1.64749
AARS alanyl-tRNA synthetase 1.64631
RLF rearranged L-myc fusion 1.64437
CCT4 chaperonin containing TCP1, subunit 4 (delta) 1.64234
CCM2 cerebral cavernous malformation 2 1.64154
PEBP1 phosphatidylethanolamine binding protein 1 1.6404
RAB11FIP4 RAB11 family interacting protein 4 (class II) 1.63723
NCOR1 nuclear receptor corepressor 1 1.637
UBC ubiquitin C 1.63635
C19ORF66 chromosome 19 open reading frame 66 1.62609
HPS1 Hermansky-Pudlak syndrome 1 1.62585
RBM48 RNA binding motif protein 48 1.62208
TMEM55B transmembrane protein 55B 1.61871
PARP8 poly (ADP-ribose) polymerase family, member 8 1.61849
TXNDC12 thioredoxin domain containing 12 (endoplasmic reticulum) 1.61753
SNAP47 synaptosomal-associated protein, 47kDa 1.61294
PCBP2 poly(rC) binding protein 2 1.60982
NRSN2 neurensin 2 1.6086
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.60571
RAB40B RAB40B, member RAS oncogene family 1.60412
MGC27345 uncharacterized protein MGC27345 1.60352
SEPP1 selenoprotein P, plasma, 1 1.60309
SLC39A11 solute carrier family 39, member 11 1.59619
RILPL1 Rab interacting lysosomal protein-like 1 1.58943
FAM3A family with sequence similarity 3, member A 1.58633
LGI3 leucine-rich repeat LGI family, member 3 1.58398
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 1.58114
CLN3 ceroid-lipofuscinosis, neuronal 3 1.57686
TMPO thymopoietin 1.57601
MED11 mediator complex subunit 11 1.56705
RPE ribulose-5-phosphate-3-epimerase 1.56518
TMEM47 transmembrane protein 47 1.56223
WDR13 WD repeat domain 13 1.56104
TMEM41A transmembrane protein 41A 1.56032
SPIN1 spindlin 1 1.5534
PDIA5 protein disulfide isomerase family A, member 5 1.55244
VCP valosin containing protein 1.54916
LOC100287896 uncharacterized LOC100287896 1.54477
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.54451
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) 1.54425
PCYOX1 prenylcysteine oxidase 1 1.5437
GPR108 G protein-coupled receptor 108 1.54261
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 1.54235
CDK12 cyclin-dependent kinase 12 1.53949
SEC22C SEC22 vesicle trafficking protein homolog C (S. cerevisiae) 1.53877
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 1.53767
FBXO45 F-box protein 45 1.53651
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 1.53611
RSRC2 arginine/serine-rich coiled-coil 2 1.53251
ITCH itchy E3 ubiquitin protein ligase 1.53096
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 1.53015
ING1 inhibitor of growth family, member 1 1.52822
GAPVD1 GTPase activating protein and VPS9 domains 1 1.52513
CDK6 cyclin-dependent kinase 6 1.52504
NMT1 N-myristoyltransferase 1 1.52062
FAM171A1 family with sequence similarity 171, member A1 1.51632
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 1.51487
SYS1 Sys1 golgi trafficking protein 1.50985
CCP110 centriolar coiled coil protein 110kDa 1.50847
ZNF766 zinc finger protein 766 1.50782
CFDP1 craniofacial development protein 1 1.50311
DCXR dicarbonyl/L-xylulose reductase 1.50187
FAM98A family with sequence similarity 98, member A 1.50082
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 1.50071
OCEL1 occludin/ELL domain containing 1 1.49935
SREBF2 sterol regulatory element binding transcription factor 2 1.49802
EIF1AD eukaryotic translation initiation factor 1A domain containing 1.49632
ANKRD55 ankyrin repeat domain 55 1.49588
RHOT1 ras homolog family member T1 1.49529
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.49293
C11ORF68 chromosome 11 open reading frame 68 1.49291
SET SET nuclear proto-oncogene 1.49278
PRDX3 peroxiredoxin 3 1.49245
MRI1 methylthioribose-1-phosphate isomerase 1 1.49206
IPO7 importin 7 1.48856
THRB thyroid hormone receptor, beta 1.48751
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 1.4868
IGF2R insulin-like growth factor 2 receptor 1.48612
LACTB2 lactamase, beta 2 1.48466
EMG1 EMG1 N1-specific pseudouridine methyltransferase 1.48431
BRSK1 BR serine/threonine kinase 1 1.48392
FAM58A family with sequence similarity 58, member A 1.47723
AGRN agrin 1.47519
EPM2AIP1 EPM2A (laforin) interacting protein 1 1.47445
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 1.47172
NNT nicotinamide nucleotide transhydrogenase 1.47127
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 1.47013
PRRC2C proline-rich coiled-coil 2C 1.46914
ERO1L ERO1-like (S. cerevisiae) 1.46769
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 1.46717
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa 1.46566
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 1.46386
ADCY5 adenylate cyclase 5 1.46349
KIAA0368 KIAA0368 1.46164
TRAPPC8 trafficking protein particle complex 8 1.46162
NLN neurolysin (metallopeptidase M3 family) 1.46122
GLB1 galactosidase, beta 1 1.45959
LINC00116 long intergenic non-protein coding RNA 116 1.45895
ZNF879 zinc finger protein 879 1.45809
RNMTL1 RNA methyltransferase like 1 1.45627
NUP50 nucleoporin 50kDa 1.45595
TMTC3 transmembrane and tetratricopeptide repeat containing 3 1.45465
BANF1 barrier to autointegration factor 1 1.45423
ANKRD36BP2 ankyrin repeat domain 36B pseudogene 2 1.45348
SLC44A1 solute carrier family 44 (choline transporter), member 1 1.45029
NCOA5 nuclear receptor coactivator 5 1.44677
PPP1R16A protein phosphatase 1, regulatory subunit 16A 1.44062
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 1.43824
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) 1.4377
FAM134A family with sequence similarity 134, member A 1.43581
ENO3 enolase 3 (beta, muscle) 1.43502
C22ORF29 chromosome 22 open reading frame 29 1.43447
RSL1D1 ribosomal L1 domain containing 1 1.43341
MRPL48 mitochondrial ribosomal protein L48 1.43279
EGLN3 egl-9 family hypoxia-inducible factor 3 1.43121
ZNF195 zinc finger protein 195 1.42655
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 1.42329
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 1.42221
SNX9 sorting nexin 9 1.41584
PBX2 pre-B-cell leukemia homeobox 2 1.41287
PIAS1 protein inhibitor of activated STAT, 1 1.41146
FXR1 fragile X mental retardation, autosomal homolog 1 1.41045
ILVBL ilvB (bacterial acetolactate synthase)-like 1.40789
NENF neudesin neurotrophic factor 1.40764
PCGF5 polycomb group ring finger 5 1.40705
ASIC3 acid sensing (proton gated) ion channel 3 1.4044
RSAD1 radical S-adenosyl methionine domain containing 1 1.40427
CAMTA2 calmodulin binding transcription activator 2 1.40277
EPRS glutamyl-prolyl-tRNA synthetase 1.40273
PREP prolyl endopeptidase 1.39936
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 1.39649
LIX1L Lix1 homolog (chicken) like 1.3956
MPC1 mitochondrial pyruvate carrier 1 1.39535
CDC14B cell division cycle 14B 1.39295
RORB RAR-related orphan receptor B 1.39281
MRPL35 mitochondrial ribosomal protein L35 1.39226
ARHGAP32 Rho GTPase activating protein 32 1.38964
SFXN4 sideroflexin 4 1.3889
BTBD1 BTB (POZ) domain containing 1 1.38802
PABPN1 poly(A) binding protein, nuclear 1 1.38683
B4GALNT2 beta-1,4-N-acetyl-galactosaminyl transferase 2 1.38621
TMEM74B transmembrane protein 74B 1.38606
PEPD peptidase D 1.38558
ZSWIM7 zinc finger, SWIM-type containing 7 1.38483
GOLGA1 golgin A1 1.38281
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) 1.38206
ABHD6 abhydrolase domain containing 6 1.37209
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 1.37032
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 1.36924
HTRA1 HtrA serine peptidase 1 1.36896
FDFT1 farnesyl-diphosphate farnesyltransferase 1 1.36894
GYS1 glycogen synthase 1 (muscle) 1.36855
PNPLA6 patatin-like phospholipase domain containing 6 1.36692
SMG8 SMG8 nonsense mediated mRNA decay factor 1.36617
MON1A MON1 secretory trafficking family member A 1.36611
RPUSD1 RNA pseudouridylate synthase domain containing 1 1.36458
KIAA1147 KIAA1147 1.36421
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 1.36362
EFTUD2 elongation factor Tu GTP binding domain containing 2 1.36278
TNRC6B trinucleotide repeat containing 6B 1.36231
C19ORF43 chromosome 19 open reading frame 43 1.35974
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 1.35875
C1ORF174 chromosome 1 open reading frame 174 1.35663
MTIF2 mitochondrial translational initiation factor 2 1.35554
CLMN calmin (calponin-like, transmembrane) 1.35506
ZMAT3 zinc finger, matrin-type 3 1.35463
RP9P retinitis pigmentosa 9 pseudogene 1.35394
PHC1 polyhomeotic homolog 1 (Drosophila) 1.35304
ZNF254 zinc finger protein 254 1.35116
WIPF2 WAS/WASL interacting protein family, member 2 1.35085
LMF2 lipase maturation factor 2 1.34432
SRPR signal recognition particle receptor (docking protein) 1.34423
TMEM199 transmembrane protein 199 1.3439
GPANK1 G patch domain and ankyrin repeats 1 1.34278
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) 1.34105
RACGAP1 Rac GTPase activating protein 1 1.33742
DCPS decapping enzyme, scavenger 1.33601
TMEM132D transmembrane protein 132D 1.33521
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 1.33515
PDLIM5 PDZ and LIM domain 5 1.33481
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 1.33388
TRIM15 tripartite motif containing 15 1.33311
SAFB scaffold attachment factor B 1.33178
GRID1 glutamate receptor, ionotropic, delta 1 1.33054
TAOK1 TAO kinase 1 1.329
SEL1L sel-1 suppressor of lin-12-like (C. elegans) 1.32882
TNPO1 transportin 1 1.3288
STXBP6 syntaxin binding protein 6 (amisyn) 1.32803
NARF nuclear prelamin A recognition factor 1.32663
MARS methionyl-tRNA synthetase 1.32489
SRSF7 serine/arginine-rich splicing factor 7 1.32487
SLC46A1 solute carrier family 46 (folate transporter), member 1 1.32415
SEZ6L2 seizure related 6 homolog (mouse)-like 2 1.32377
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa 1.32311
CUTC cutC copper transporter 1.32294
LOC286149 uncharacterized LOC286149 1.32192
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase 1.32106
TRIM24 tripartite motif containing 24 1.31948
MOB1A MOB kinase activator 1A 1.31932

decreased expression

Symbol Name Standardized Value
RRM1 ribonucleotide reductase M1 -2.54573
LYPLAL1 lysophospholipase-like 1 -2.49401
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) -2.46649
PAN3 PAN3 poly(A) specific ribonuclease subunit -2.4368
PTPMT1 protein tyrosine phosphatase, mitochondrial 1 -2.41378
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) -2.34274
PI4KB phosphatidylinositol 4-kinase, catalytic, beta -2.33919
BIRC6 baculoviral IAP repeat containing 6 -2.32382
RPL35 ribosomal protein L35 -2.29304
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28 -2.27592
RNF10 ring finger protein 10 -2.26632
UFM1 ubiquitin-fold modifier 1 -2.24602
MFSD8 major facilitator superfamily domain containing 8 -2.24237
MTF2 metal response element binding transcription factor 2 -2.24222
PIBF1 progesterone immunomodulatory binding factor 1 -2.22343
TSC1 tuberous sclerosis 1 -2.22058
COLEC12 collectin sub-family member 12 -2.22013
LOC100506606 uncharacterized LOC100506606 -2.21516
PTCD3 pentatricopeptide repeat domain 3 -2.2091
MTA3 metastasis associated 1 family, member 3 -2.1803
RNLS renalase, FAD-dependent amine oxidase -2.13479
NIPAL3 NIPA-like domain containing 3 -2.11001
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 -2.10973
C20ORF27 chromosome 20 open reading frame 27 -2.09087
FBXO38 F-box protein 38 -2.08979
SIPA1L1 signal-induced proliferation-associated 1 like 1 -2.0765
TMEM115 transmembrane protein 115 -2.07253
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 -2.0708
FAM192A family with sequence similarity 192, member A -2.02986
RPL15 ribosomal protein L15 -2.02022
MAPKAP1 mitogen-activated protein kinase associated protein 1 -2.01661
KIF22 kinesin family member 22 -2.01356
ATF6 activating transcription factor 6 -2.01268
ASB7 ankyrin repeat and SOCS box containing 7 -2.01095
WASF3 WAS protein family, member 3 -2.00863
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI -2.00346
MBLAC2 metallo-beta-lactamase domain containing 2 -1.99122
CYB5A cytochrome b5 type A (microsomal) -1.98516
FAM214A family with sequence similarity 214, member A -1.98459
AP3M1 adaptor-related protein complex 3, mu 1 subunit -1.97203
CCDC53 coiled-coil domain containing 53 -1.97101
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial -1.96978
WDR61 WD repeat domain 61 -1.96102
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -1.9595
EIF3A eukaryotic translation initiation factor 3, subunit A -1.94144
TMEM200C transmembrane protein 200C -1.93867
WDR75 WD repeat domain 75 -1.93626
ZMYM4 zinc finger, MYM-type 4 -1.93522
RPS5 ribosomal protein S5 -1.92941
CELF1 CUGBP, Elav-like family member 1 -1.92768
SAP30BP SAP30 binding protein -1.91967
BAHD1 bromo adjacent homology domain containing 1 -1.91337
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 -1.91067
EBNA1BP2 EBNA1 binding protein 2 -1.90768
TRIM68 tripartite motif containing 68 -1.90723
SDF4 stromal cell derived factor 4 -1.89678
CCDC50 coiled-coil domain containing 50 -1.89593
MNS1 meiosis-specific nuclear structural 1 -1.89332
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 -1.88849
COL6A1 collagen, type VI, alpha 1 -1.88714
RPL27 ribosomal protein L27 -1.88527
OSGIN2 oxidative stress induced growth inhibitor family member 2 -1.87074
HLTF helicase-like transcription factor -1.85815
TTC4 tetratricopeptide repeat domain 4 -1.8545
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 -1.85178
FBXL12 F-box and leucine-rich repeat protein 12 -1.85137
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 -1.8481
EXOSC7 exosome component 7 -1.84373
WBP4 WW domain binding protein 4 -1.84315
MPPE1 metallophosphoesterase 1 -1.83959
MYOM3 myomesin 3 -1.83397
VPS37A vacuolar protein sorting 37 homolog A (S. cerevisiae) -1.83261
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -1.83055
UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2 -1.8305
NFYB nuclear transcription factor Y, beta -1.82805
TSG101 tumor susceptibility 101 -1.82693
ACSM5 acyl-CoA synthetase medium-chain family member 5 -1.82647
METTL3 methyltransferase like 3 -1.82098
FAIM Fas apoptotic inhibitory molecule -1.80734
SMAD4 SMAD family member 4 -1.78856
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa -1.78804
NFX1 nuclear transcription factor, X-box binding 1 -1.78793
PSEN2 presenilin 2 -1.78679
C11ORF31 chromosome 11 open reading frame 31 -1.78647
EHD1 EH-domain containing 1 -1.78476
ATP10D ATPase, class V, type 10D -1.77406
SRR serine racemase -1.7732
KIAA1468 KIAA1468 -1.77148
RIC8A RIC8 guanine nucleotide exchange factor A -1.76883
ANAPC10 anaphase promoting complex subunit 10 -1.76703
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa -1.7656
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like -1.76211
TMCO1 transmembrane and coiled-coil domains 1 -1.7579
PTPRA protein tyrosine phosphatase, receptor type, A -1.75455
ANAPC1 anaphase promoting complex subunit 1 -1.75202
ARID4A AT rich interactive domain 4A (RBP1-like) -1.75182
RPL11 ribosomal protein L11 -1.75139
TMEM184C transmembrane protein 184C -1.74065
LIN7C lin-7 homolog C (C. elegans) -1.73566
TRIQK triple QxxK/R motif containing -1.73551
METTL10 methyltransferase like 10 -1.73485
CBR3 carbonyl reductase 3 -1.73172
HAUS6 HAUS augmin-like complex, subunit 6 -1.73095
SFPQ splicing factor proline/glutamine-rich -1.72385
REXO1 REX1, RNA exonuclease 1 homolog (S. cerevisiae) -1.72351
FAM228B family with sequence similarity 228, member B -1.72179
SH3BP5 SH3-domain binding protein 5 (BTK-associated) -1.7214
ZNF510 zinc finger protein 510 -1.7209
RPSAP20 ribosomal protein SA pseudogene 20 -1.71437
KIAA1191 KIAA1191 -1.70822
CSNK1D casein kinase 1, delta -1.70512
USP9X ubiquitin specific peptidase 9, X-linked -1.70134
ANGEL2 angel homolog 2 (Drosophila) -1.69529
STX17 syntaxin 17 -1.68679
RPS25 ribosomal protein S25 -1.68668
POMP proteasome maturation protein -1.68649
MRPL13 mitochondrial ribosomal protein L13 -1.68123
HGS hepatocyte growth factor-regulated tyrosine kinase substrate -1.68084
EXOSC4 exosome component 4 -1.68044
MTHFSD methenyltetrahydrofolate synthetase domain containing -1.67867
BLZF1 basic leucine zipper nuclear factor 1 -1.66507
ZBTB8A zinc finger and BTB domain containing 8A -1.66305
RPL26 ribosomal protein L26 -1.66024
SNF8 SNF8, ESCRT-II complex subunit -1.66005
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 -1.66002
GPATCH4 G patch domain containing 4 -1.65887
ITM2B integral membrane protein 2B -1.65695
FBXO25 F-box protein 25 -1.65323
ST7L suppression of tumorigenicity 7 like -1.65164
C4ORF29 chromosome 4 open reading frame 29 -1.6513
INO80 INO80 complex subunit -1.65009
SENP6 SUMO1/sentrin specific peptidase 6 -1.64997
ISLR immunoglobulin superfamily containing leucine-rich repeat -1.64434
TCTA T-cell leukemia translocation altered -1.64419
RPL24 ribosomal protein L24 -1.6403
DCAF15 DDB1 and CUL4 associated factor 15 -1.639
MED22 mediator complex subunit 22 -1.63828
RGS5 regulator of G-protein signaling 5 -1.63754
TFAP2D transcription factor AP-2 delta (activating enhancer binding protein 2 delta) -1.63713
CCDC112 coiled-coil domain containing 112 -1.63649
NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa -1.62622
ZFYVE26 zinc finger, FYVE domain containing 26 -1.62547
ERH enhancer of rudimentary homolog (Drosophila) -1.61748
PHF20L1 PHD finger protein 20-like 1 -1.61666
TGFA transforming growth factor, alpha -1.61333
EIF3H eukaryotic translation initiation factor 3, subunit H -1.61071
EPS8 epidermal growth factor receptor pathway substrate 8 -1.60456
H2AFJ H2A histone family, member J -1.60364
GMFB glia maturation factor, beta -1.60251
FBXO22 F-box protein 22 -1.60182
SCRN1 secernin 1 -1.60011
RAD17 RAD17 homolog (S. pombe) -1.59676
TOX4 TOX high mobility group box family member 4 -1.5945
PINK1 PTEN induced putative kinase 1 -1.59391
BDH1 3-hydroxybutyrate dehydrogenase, type 1 -1.5925
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2 -1.59205
TBC1D22A TBC1 domain family, member 22A -1.59191
RPS10 ribosomal protein S10 -1.58641
NOXA1 NADPH oxidase activator 1 -1.58427
PPP1R35 protein phosphatase 1, regulatory subunit 35 -1.5831
PPIL3 peptidylprolyl isomerase (cyclophilin)-like 3 -1.58171
CHID1 chitinase domain containing 1 -1.57661
RPS18 ribosomal protein S18 -1.57431
FBXO11 F-box protein 11 -1.56814
ATXN2 ataxin 2 -1.56813
ZAK sterile alpha motif and leucine zipper containing kinase AZK -1.56767
GNPTG N-acetylglucosamine-1-phosphate transferase, gamma subunit -1.56636
WDR88 WD repeat domain 88 -1.56159
VPS25 vacuolar protein sorting 25 homolog (S. cerevisiae) -1.55492
UROD uroporphyrinogen decarboxylase -1.5548
NOTCH3 notch 3 -1.55435
PHB2 prohibitin 2 -1.5535
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase -1.55321
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 -1.55082
PPP5D1 PPP5 tetratricopeptide repeat domain containing 1 -1.54809
STRN striatin, calmodulin binding protein -1.54232
HAUS1 HAUS augmin-like complex, subunit 1 -1.53433
CNPY2 canopy FGF signaling regulator 2 -1.53109
TPCN2 two pore segment channel 2 -1.52727
SSBP3 single stranded DNA binding protein 3 -1.52506
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 -1.52459
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) -1.52327
ZNF304 zinc finger protein 304 -1.52098
RPL6 ribosomal protein L6 -1.52053
C11ORF57 chromosome 11 open reading frame 57 -1.51994
RPS23 ribosomal protein S23 -1.51921
SYNRG synergin, gamma -1.51437
SRP9 signal recognition particle 9kDa -1.51354
EDEM2 ER degradation enhancer, mannosidase alpha-like 2 -1.51303
TMEM54 transmembrane protein 54 -1.51263
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit -1.51237
LOC100506870 -1.51205
C7ORF73 chromosome 7 open reading frame 73 -1.51064
UBE2E1 ubiquitin-conjugating enzyme E2E 1 -1.50974
TANK TRAF family member-associated NFKB activator -1.50897
H2AFV H2A histone family, member V -1.50681
SSC5D scavenger receptor cysteine rich family, 5 domains -1.50618
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -1.49635
EIF1AX eukaryotic translation initiation factor 1A, X-linked -1.49301
LARP4B La ribonucleoprotein domain family, member 4B -1.49226
RBM8A RNA binding motif protein 8A -1.49144
FXN frataxin -1.48976
PRR5 proline rich 5 (renal) -1.48768
MRFAP1L1 Morf4 family associated protein 1-like 1 -1.48521
VRK1 vaccinia related kinase 1 -1.48311
OTUD1 OTU deubiquitinase 1 -1.48087
TFCP2 transcription factor CP2 -1.48048
LMBR1L limb development membrane protein 1-like -1.47923
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) -1.47818
SEPHS1 selenophosphate synthetase 1 -1.47548
SYTL2 synaptotagmin-like 2 -1.47329
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) -1.4721
ILKAP integrin-linked kinase-associated serine/threonine phosphatase -1.46827
APOE apolipoprotein E -1.46806
RABGAP1 RAB GTPase activating protein 1 -1.46712
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain -1.46671
RPS24 ribosomal protein S24 -1.46561
SAP30L SAP30-like -1.4634
MAP2K6 mitogen-activated protein kinase kinase 6 -1.46325
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -1.46234
ELK1 ELK1, member of ETS oncogene family -1.46096
ANKRD6 ankyrin repeat domain 6 -1.45226
ZNF271P zinc finger protein 271, pseudogene -1.45069
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa -1.44898
KLK12 kallikrein-related peptidase 12 -1.44611
RPS15 ribosomal protein S15 -1.44605
TRIM39 tripartite motif containing 39 -1.44511
C1ORF131 chromosome 1 open reading frame 131 -1.44305
RPS17 ribosomal protein S17 -1.44065
IREB2 iron-responsive element binding protein 2 -1.44036
FAM122B family with sequence similarity 122B -1.43893
SDE2 SDE2 telomere maintenance homolog (S. pombe) -1.43783
ZNF256 zinc finger protein 256 -1.43633
MAN2B2 mannosidase, alpha, class 2B, member 2 -1.43563
CBX1 chromobox homolog 1 -1.43427
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -1.43325
TEX2 testis expressed 2 -1.43277
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) -1.4312
ATPIF1 ATPase inhibitory factor 1 -1.42982
C17ORF58 chromosome 17 open reading frame 58 -1.42946
DAAM1 dishevelled associated activator of morphogenesis 1 -1.42849
SEPT7 septin 7 -1.42766
C20ORF194 chromosome 20 open reading frame 194 -1.42561
H2AFY H2A histone family, member Y -1.41967
C8ORF33 chromosome 8 open reading frame 33 -1.41923
USP24 ubiquitin specific peptidase 24 -1.41881
PEMT phosphatidylethanolamine N-methyltransferase -1.41838
POLR1C polymerase (RNA) I polypeptide C, 30kDa -1.41726
TMEM50A transmembrane protein 50A -1.41644
FAM104A family with sequence similarity 104, member A -1.41545
DPH5 diphthamide biosynthesis 5 -1.41264
EEA1 early endosome antigen 1 -1.41221
C6ORF203 chromosome 6 open reading frame 203 -1.41218
THUMPD2 THUMP domain containing 2 -1.41157
ABLIM3 actin binding LIM protein family, member 3 -1.41155
ARRDC4 arrestin domain containing 4 -1.4098
ZC4H2 zinc finger, C4H2 domain containing -1.40912
TRRAP transformation/transcription domain-associated protein -1.40649
TRPV1 transient receptor potential cation channel, subfamily V, member 1 -1.405
CPNE2 copine II -1.40401
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit -1.40277
HNRNPA1L2 heterogeneous nuclear ribonucleoprotein A1-like 2 -1.40236
KIF3B kinesin family member 3B -1.40132
COMMD2 COMM domain containing 2 -1.40125
TCEAL8 transcription elongation factor A (SII)-like 8 -1.39953
CREM cAMP responsive element modulator -1.39948
DNALI1 dynein, axonemal, light intermediate chain 1 -1.39915
NBPF8 neuroblastoma breakpoint family, member 8 -1.39878
ROMO1 reactive oxygen species modulator 1 -1.39874
AGFG1 ArfGAP with FG repeats 1 -1.39684
DKFZP434K028 uncharacterized LOC26070 -1.39529
MSTO1 misato 1, mitochondrial distribution and morphology regulator -1.39515
PARP4 poly (ADP-ribose) polymerase family, member 4 -1.39277
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed -1.39275
NR2F6 nuclear receptor subfamily 2, group F, member 6 -1.3923
CRCP CGRP receptor component -1.39174
SNX30 sorting nexin family member 30 -1.39162
HSPA14 heat shock 70kDa protein 14 -1.38925
FAM133A family with sequence similarity 133, member A -1.38919
HOOK3 hook microtubule-tethering protein 3 -1.3878
MAML2 mastermind-like 2 (Drosophila) -1.38758
RWDD3 RWD domain containing 3 -1.38634
WRB tryptophan rich basic protein -1.38621
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae) -1.3823
KATNA1 katanin p60 (ATPase containing) subunit A 1 -1.38226
C19ORF60 chromosome 19 open reading frame 60 -1.38138
THOP1 thimet oligopeptidase 1 -1.38055
PGBD1 piggyBac transposable element derived 1 -1.37756
HBEGF heparin-binding EGF-like growth factor -1.37608
GPATCH2L G patch domain containing 2-like -1.37203
TMEM14B transmembrane protein 14B -1.37094
TMEM106B transmembrane protein 106B -1.3706
RMI1 RecQ mediated genome instability 1 -1.37
DEFB125 defensin, beta 125 -1.36893
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -1.36862
KRIT1 KRIT1, ankyrin repeat containing -1.36859
ZKSCAN5 zinc finger with KRAB and SCAN domains 5 -1.36842
PLRG1 pleiotropic regulator 1 -1.36589
PSMC3IP PSMC3 interacting protein -1.36511
RPL22 ribosomal protein L22 -1.3651