| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pasireotide (acetate) perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pasireotide (acetate)_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | 0.319124 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.150942 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.119696 |
| RPS6 | ribosomal protein S6 | 0.0962713 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0909589 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0813161 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0707912 |
| NRP2 | neuropilin 2 | 0.0686184 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.066426 |
| MKI67 | marker of proliferation Ki-67 | 0.0656753 |
| RRBP1 | ribosome binding protein 1 | 0.0642868 |
| JAK1 | Janus kinase 1 | 0.0634675 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0628663 |
| AHNAK | AHNAK nucleoprotein | 0.0620098 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0609774 |
| TPM3 | tropomyosin 3 | 0.0607743 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0607008 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.056109 |
| MT2A | metallothionein 2A | 0.0560183 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0535839 |
| COL4A1 | collagen, type IV, alpha 1 | 0.052398 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0518732 |
| APP | amyloid beta (A4) precursor protein | 0.0507842 |
| GOLGA4 | golgin A4 | 0.0500229 |
| SMAD3 | SMAD family member 3 | 0.0491987 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0486734 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0474216 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.045995 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0456055 |
| PRRC2C | proline-rich coiled-coil 2C | 0.045461 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0451463 |
| YBX1 | Y box binding protein 1 | 0.044724 |
| SFTPA2 | surfactant protein A2 | 0.043201 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0430978 |
| TPR | translocated promoter region, nuclear basket protein | 0.0429379 |
| RPL19 | ribosomal protein L19 | 0.0425292 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0420037 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0415141 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0414903 |
| ERBIN | erbb2 interacting protein | 0.0392369 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0391332 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0388685 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0388 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0387579 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0377402 |
| RPL23 | ribosomal protein L23 | 0.0375976 |
| FMNL2 | formin-like 2 | 0.0373761 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0367714 |
| RPL3 | ribosomal protein L3 | 0.0366705 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0364202 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0360789 |
| NIBAN1 | niban apoptosis regulator 1 | 0.036073 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0355557 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0346998 |
| CENPF | centromere protein F, 350/400kDa | 0.0343648 |
| NAV2 | neuron navigator 2 | 0.0339287 |
| RPL26 | ribosomal protein L26 | 0.0338561 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0336378 |
| MSN | moesin | 0.0334774 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0332933 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0332868 |
| RPS4X | ribosomal protein S4, X-linked | 0.0330787 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0329618 |
| RPS2 | ribosomal protein S2 | 0.0328493 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0323555 |
| MYOF | myoferlin | 0.0323049 |
| FLNB | filamin B, beta | 0.0322888 |
| GOLGB1 | golgin B1 | 0.0320862 |
| LOXL2 | lysyl oxidase-like 2 | 0.0320633 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0318728 |
| CTBP2 | C-terminal binding protein 2 | 0.0317926 |
| PAX8 | paired box 8 | 0.0317075 |
| CADM1 | cell adhesion molecule 1 | 0.031634 |
| CALU | calumenin | 0.0314677 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.030971 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.030819 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.03074 |
| PLK2 | polo-like kinase 2 | 0.0307303 |
| CAVIN1 | caveolae associated protein 1 | 0.0306659 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0306122 |
| RPL12 | ribosomal protein L12 | 0.0304949 |
| RAD21 | RAD21 homolog (S. pombe) | 0.030438 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0304112 |
| MYO10 | myosin X | 0.0302801 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0298955 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0295954 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0290109 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0289946 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0289768 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0285185 |
| ANLN | anillin, actin binding protein | 0.0284569 |
| DSG2 | desmoglein 2 | 0.0283978 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0283724 |
| NCKAP1 | NCK-associated protein 1 | 0.0281522 |
| FAT1 | FAT atypical cadherin 1 | 0.0279617 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.0277365 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0276272 |
| DST | dystonin | 0.0274998 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0270814 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0269897 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.29714 |
| VIM | vimentin | -0.128093 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.125886 |
| GPC6 | glypican 6 | -0.125116 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.120741 |
| FRMD4A | FERM domain containing 4A | -0.101868 |
| CP | ceruloplasmin (ferroxidase) | -0.0845754 |
| FTL | ferritin, light polypeptide | -0.0728824 |
| CTSD | cathepsin D | -0.0588336 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0557319 |
| PLIN2 | perilipin 2 | -0.0549273 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.05248 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0515979 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0446043 |
| OXR1 | oxidation resistance 1 | -0.0411945 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0410535 |
| TPM4 | tropomyosin 4 | -0.0388236 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0379118 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0366722 |
| MYADM | myeloid-associated differentiation marker | -0.0362499 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0362359 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0361923 |
| GLIS3 | GLIS family zinc finger 3 | -0.0349088 |
| ACTG1 | actin gamma 1 | -0.0343909 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0339591 |
| POTEF | POTE ankyrin domain family, member F | -0.0337397 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0333844 |
| TPM1 | tropomyosin 1 (alpha) | -0.0327303 |
| BNC2 | basonuclin 2 | -0.0323007 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0320142 |
| S100A6 | S100 calcium binding protein A6 | -0.0317722 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0317707 |
| ANXA4 | annexin A4 | -0.0317106 |
| ITM2B | integral membrane protein 2B | -0.030895 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0308322 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.0308305 |
| GDF15 | growth differentiation factor 15 | -0.0305958 |
| EHBP1 | EH domain binding protein 1 | -0.0305714 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0304602 |
| KYNU | kynureninase | -0.030087 |
| TUBA1B | tubulin, alpha 1b | -0.0298253 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0290872 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0289828 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0278886 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0278776 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0265573 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0265322 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0261521 |
| HLA-B | major histocompatibility complex, class I, B | -0.0252718 |
| ADGRG1 | adhesion G protein-coupled receptor G1 | -0.0246934 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0244523 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0241375 |
| CMIP | c-Maf inducing protein | -0.0239664 |
| HLA-E | major histocompatibility complex, class I, E | -0.0237204 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0234427 |
| TMEM165 | transmembrane protein 165 | -0.0233459 |
| PRKCA | protein kinase C, alpha | -0.0232142 |
| MMP7 | matrix metallopeptidase 7 | -0.0228356 |
| CD68 | CD68 molecule | -0.0227858 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0225934 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0225652 |
| TUBA1C | tubulin, alpha 1c | -0.0224823 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0222752 |
| NF1 | neurofibromin 1 | -0.0222556 |
| STK17A | serine/threonine kinase 17a | -0.0220407 |
| LOC112694756 | uncharaterized LOC112694756 | -0.021927 |
| RIGI | RNA sensor RIG-I | -0.0218249 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0217636 |
| SDCBP | syndecan binding protein (syntenin) | -0.0215225 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.0213099 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0211961 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0211382 |
| IL6 | interleukin 6 | -0.0209128 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0208236 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0206893 |
| GPC5 | glypican 5 | -0.0203856 |
| DSTN | destrin (actin depolymerizing factor) | -0.020059 |
| PTH2R | parathyroid hormone 2 receptor | -0.0199283 |
| SQLE | squalene epoxidase | -0.0199221 |
| RPLP0 | ribosomal protein, large, P0 | -0.0198646 |
| CUX1 | cut-like homeobox 1 | -0.0197363 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0197286 |
| RPS20 | ribosomal protein S20 | -0.0196442 |
| DGKI | diacylglycerol kinase, iota | -0.0195776 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.019553 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0192608 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0190761 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.0188819 |
| MSMO1 | methylsterol monooxygenase 1 | -0.0187753 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -0.0184999 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.018331 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0183256 |
| FAM13A | family with sequence similarity 13, member A | -0.01826 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0180398 |
| FN1 | fibronectin 1 | -0.0179684 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0176508 |
| IL32 | interleukin 32 | -0.0175057 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 | -0.017453 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | -0.0172035 |
| SMIM44 | small integral membrane protein 44 | -0.0171907 |
