| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pasireotide (acetate) perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pasireotide (acetate)_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.319128 |
| RPS6 | ribosomal protein S6 | 0.142442 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0895038 |
| KYNU | kynureninase | 0.0894332 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0857805 |
| MCL1 | myeloid cell leukemia 1 | 0.081928 |
| ASPH | aspartate beta-hydroxylase | 0.0735741 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.070076 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0673527 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0629096 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0621579 |
| STC1 | stanniocalcin 1 | 0.0602472 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0598232 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.05703 |
| RPS2 | ribosomal protein S2 | 0.0565062 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0527532 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0483787 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0481698 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0474927 |
| VMP1 | vacuole membrane protein 1 | 0.0472855 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0466297 |
| MSN | moesin | 0.0439567 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0439396 |
| VCL | vinculin | 0.0428799 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0425178 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0405766 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0405513 |
| USP47 | ubiquitin specific peptidase 47 | 0.0392245 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0390851 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0385933 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0384547 |
| RNF145 | ring finger protein 145 | 0.038314 |
| RPS12 | ribosomal protein S12 | 0.0377045 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0375946 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0365314 |
| RASA2 | RAS p21 protein activator 2 | 0.0364879 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0362295 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0359434 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0353688 |
| WWC1 | WW and C2 domain containing 1 | 0.0348102 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0347999 |
| RPL3 | ribosomal protein L3 | 0.0347625 |
| MYO10 | myosin X | 0.0343243 |
| RPL23 | ribosomal protein L23 | 0.0341193 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0335659 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0335465 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0335306 |
| RPS17 | ribosomal protein S17 | 0.0334775 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0334445 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.033381 |
| CD44 | CD44 molecule (Indian blood group) | 0.0329644 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0329103 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0323122 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0321058 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0320869 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0317361 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0313108 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0312242 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0308793 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0304661 |
| MT1X | metallothionein 1X | 0.0302255 |
| TOP1 | topoisomerase (DNA) I | 0.0299257 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0292708 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.029268 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0290363 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.028735 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0284042 |
| BMP6 | bone morphogenetic protein 6 | 0.0281298 |
| CENPF | centromere protein F, 350/400kDa | 0.0279346 |
| TPM3 | tropomyosin 3 | 0.027888 |
| LAMC2 | laminin, gamma 2 | 0.0277252 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0271127 |
| RPL18 | ribosomal protein L18 | 0.0270539 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0269422 |
| MKI67 | marker of proliferation Ki-67 | 0.0265809 |
| RPL26 | ribosomal protein L26 | 0.0259613 |
| ANKRD11 | ankyrin repeat domain 11 | 0.025602 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0255656 |
| OGA | O-GlcNAcase | 0.0254557 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0254155 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0253075 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0251488 |
| ECT2 | epithelial cell transforming 2 | 0.0251175 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.024911 |
| BCL2L1 | BCL2-like 1 | 0.0248626 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0248499 |
| RPL19 | ribosomal protein L19 | 0.0247022 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0246895 |
| UBC | ubiquitin C | 0.0246665 |
| SFTPA2 | surfactant protein A2 | 0.0245326 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0243318 |
| ATP13A3 | ATPase type 13A3 | 0.0242176 |
| RPS8 | ribosomal protein S8 | 0.0241963 |
| DST | dystonin | 0.0240675 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0239893 |
| NUP58 | nucleoporin 58 | 0.0237637 |
| RPS7 | ribosomal protein S7 | 0.0235884 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.023466 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0233144 |
| RPL37A | ribosomal protein L37a | 0.0231539 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.191925 |
| ACTG1 | actin gamma 1 | -0.142736 |
| ANXA2 | annexin A2 | -0.103794 |
| TMSB10 | thymosin beta 10 | -0.100258 |
| FTL | ferritin, light polypeptide | -0.0985563 |
| EFNA5 | ephrin-A5 | -0.0873954 |
| CA12 | carbonic anhydrase XII | -0.0860361 |
| RNF213 | ring finger protein 213 | -0.0746254 |
| LDHA | lactate dehydrogenase A | -0.0735708 |
| NDRG1 | N-myc downstream regulated 1 | -0.0734912 |
| VIM | vimentin | -0.0727302 |
| RPLP1 | ribosomal protein, large, P1 | -0.0718726 |
| EGFR | epidermal growth factor receptor | -0.0695706 |
| ANXA4 | annexin A4 | -0.066647 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.063275 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0630266 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0570275 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0551931 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.054892 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0528022 |
| RIGI | RNA sensor RIG-I | -0.0513299 |
| TNS3 | tensin 3 | -0.0494006 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0484309 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0482409 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0471683 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0469733 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0459584 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.045389 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0445546 |
| MYO1E | myosin IE | -0.0445132 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0429571 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.042443 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0418524 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0415017 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0413635 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0411727 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0396332 |
| S100A6 | S100 calcium binding protein A6 | -0.0395092 |
| PGK1 | phosphoglycerate kinase 1 | -0.0393077 |
| AUTS2 | autism susceptibility candidate 2 | -0.039282 |
| RIN2 | Ras and Rab interactor 2 | -0.0391731 |
| RPS16 | ribosomal protein S16 | -0.0389125 |
| FA2H | fatty acid 2-hydroxylase | -0.0372728 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0368262 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0364378 |
| ZFHX3 | zinc finger homeobox 3 | -0.0362365 |
| TPM4 | tropomyosin 4 | -0.0361907 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0358637 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0356 |
| LOXL2 | lysyl oxidase-like 2 | -0.0355964 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0347534 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0339557 |
| KRT81 | keratin 81, type II | -0.0324455 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0317983 |
| CP | ceruloplasmin (ferroxidase) | -0.0317719 |
| RRBP1 | ribosome binding protein 1 | -0.0317557 |
| PRKCA | protein kinase C, alpha | -0.0315169 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0315161 |
| EHBP1 | EH domain binding protein 1 | -0.0310483 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0307007 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.030558 |
| SLC38A1 | solute carrier family 38, member 1 | -0.030257 |
| CALU | calumenin | -0.0301132 |
| FLNB | filamin B, beta | -0.0298256 |
| DAPK1 | death-associated protein kinase 1 | -0.029368 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.029311 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0290586 |
| S100A10 | S100 calcium binding protein A10 | -0.0285332 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0284803 |
| SP100 | SP100 nuclear antigen | -0.0283159 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0282985 |
| RPL35A | ribosomal protein L35a | -0.0281485 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0281234 |
| ENO1 | enolase 1, (alpha) | -0.0274408 |
| NF1 | neurofibromin 1 | -0.0272811 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0270592 |
| SQSTM1 | sequestosome 1 | -0.0269649 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0268989 |
| LTBP4 | latent transforming growth factor beta binding protein 4 | -0.0266968 |
| SBF2 | SET binding factor 2 | -0.026638 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | -0.026298 |
| SEPTIN2 | septin 2 | -0.0250457 |
| POTEF | POTE ankyrin domain family, member F | -0.0248526 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0243986 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0236168 |
| PYGL | phosphorylase, glycogen, liver | -0.0234214 |
| MT2A | metallothionein 2A | -0.0233842 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0233802 |
| RPL38 | ribosomal protein L38 | -0.0232523 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.023047 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0229015 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0224677 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0224276 |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 | -0.0221319 |
| RPS29 | ribosomal protein S29 | -0.0219395 |
| IER3 | immediate early response 3 | -0.0218816 |
| DIAPH2 | diaphanous-related formin 2 | -0.0218328 |
| DENND4C | DENN/MADD domain containing 4C | -0.0217482 |
| LAMB3 | laminin, beta 3 | -0.0215582 |
| PLSCR1 | phospholipid scramblase 1 | -0.0214974 |
