| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pasireotide (acetate) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pasireotide (acetate)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.155911 |
| VEGFA | vascular endothelial growth factor A | 0.147453 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0818096 |
| CENPF | centromere protein F, 350/400kDa | 0.0753043 |
| MKI67 | marker of proliferation Ki-67 | 0.0745069 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0744082 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0681036 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.065702 |
| RPL3 | ribosomal protein L3 | 0.0647852 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0581396 |
| VIM | vimentin | 0.0569048 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0553352 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0542928 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0535789 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0529325 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.050929 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0453235 |
| SFTPA2 | surfactant protein A2 | 0.0439683 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0438997 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0435461 |
| ITGAV | integrin, alpha V | 0.0424825 |
| H1-4 | H1.4 linker histone, cluster member | 0.0423407 |
| PRELID2 | PRELI domain containing 2 | 0.041592 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0414452 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0411324 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0409185 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0403964 |
| PTK2 | protein tyrosine kinase 2 | 0.0388938 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0383462 |
| NFIB | nuclear factor I/B | 0.0380431 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.037838 |
| DST | dystonin | 0.0374303 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0356529 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.035105 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0348051 |
| STMN1 | stathmin 1 | 0.0344959 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0343595 |
| PKM | pyruvate kinase, muscle | 0.0339757 |
| CDK19 | cyclin-dependent kinase 19 | 0.0333167 |
| SETD5 | SET domain containing 5 | 0.0327827 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0326281 |
| NIN | ninein (GSK3B interacting protein) | 0.0325889 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.032449 |
| DOCK3 | dedicator of cytokinesis 3 | 0.03184 |
| YBX1 | Y box binding protein 1 | 0.0317071 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0315974 |
| ZNF638 | zinc finger protein 638 | 0.0313483 |
| CENPE | centromere protein E, 312kDa | 0.0312444 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0311558 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0311545 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0308349 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0300375 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0293877 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.029235 |
| BRD2 | bromodomain containing 2 | 0.0291797 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0290764 |
| MEST | mesoderm specific transcript | 0.0290379 |
| PCM1 | pericentriolar material 1 | 0.0289784 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0289757 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0285422 |
| RPS6 | ribosomal protein S6 | 0.0284203 |
| RPL4 | ribosomal protein L4 | 0.0283305 |
| TAOK1 | TAO kinase 1 | 0.0281921 |
| COL5A2 | collagen, type V, alpha 2 | 0.0280172 |
| TMSB4X | thymosin beta 4, X-linked | 0.0280023 |
| PTEN | phosphatase and tensin homolog | 0.0279035 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0278106 |
| STAG2 | stromal antigen 2 | 0.027371 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0271821 |
| TET1 | tet methylcytosine dioxygenase 1 | 0.0270411 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0268954 |
| RPL32 | ribosomal protein L32 | 0.0266472 |
| FAM168A | family with sequence similarity 168, member A | 0.0266388 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0266111 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0264385 |
| RNF145 | ring finger protein 145 | 0.0263692 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.026348 |
| METTL15 | methyltransferase like 15 | 0.0262749 |
| RBM39 | RNA binding motif protein 39 | 0.0260008 |
| PDS5A | PDS5 cohesin associated factor A | 0.0257059 |
| SET | SET nuclear proto-oncogene | 0.0255657 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0254093 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0253968 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0253716 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0251955 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.0251825 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0251165 |
| ADM | adrenomedullin | 0.0248652 |
| SON | SON DNA binding protein | 0.0247815 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0246602 |
| BCOR | BCL6 corepressor | 0.024659 |
| TXNRD1 | thioredoxin reductase 1 | 0.0246209 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0243067 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.024181 |
| PDE10A | phosphodiesterase 10A | 0.024132 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0241227 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0239683 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0238219 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0237514 |
| CCNL1 | cyclin L1 | 0.0236456 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PEG10 | paternally expressed 10 | -0.110062 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.109888 |
| CADM2 | cell adhesion molecule 2 | -0.0851721 |
| KAZN | kazrin, periplakin interacting protein | -0.0740414 |
| MT2A | metallothionein 2A | -0.064834 |
| RPS24 | ribosomal protein S24 | -0.0606731 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0503937 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0470806 |
| MEOX2 | mesenchyme homeobox 2 | -0.0448926 |
| RLF | rearranged L-myc fusion | -0.043199 |
| HMGA2 | high mobility group AT-hook 2 | -0.0414054 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0376178 |
| NBEA | neurobeachin | -0.0375934 |
| TULP4 | tubby like protein 4 | -0.0367485 |
| RPL37 | ribosomal protein L37 | -0.0365038 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0353472 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.03523 |
| NF1 | neurofibromin 1 | -0.0348434 |
| RPL34 | ribosomal protein L34 | -0.0345738 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0341894 |
| ZFHX3 | zinc finger homeobox 3 | -0.0336894 |
| RPL35A | ribosomal protein L35a | -0.033499 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0334775 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0327052 |
| RPL9 | ribosomal protein L9 | -0.0326022 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0325 |
| TUT4 | terminal uridylyl transferase 4 | -0.0320178 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0313591 |
| SMYD3 | SET and MYND domain containing 3 | -0.0312799 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0308789 |
| COL1A2 | collagen, type I, alpha 2 | -0.0304837 |
| RPL12 | ribosomal protein L12 | -0.0294022 |
| RPS23 | ribosomal protein S23 | -0.0293909 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0290102 |
| SIK3 | SIK family kinase 3 | -0.0286056 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0285212 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0283758 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.0282679 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.028019 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0274076 |
| UST | uronyl-2-sulfotransferase | -0.0271614 |
| RPL31 | ribosomal protein L31 | -0.0269561 |
| DEK | DEK proto-oncogene | -0.0264307 |
| TMSB10 | thymosin beta 10 | -0.0264186 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0263448 |
| RPL36A | ribosomal protein L36a | -0.0262834 |
| JMJD1C | jumonji domain containing 1C | -0.0260035 |
| RPLP0 | ribosomal protein, large, P0 | -0.0259077 |
| TRIM24 | tripartite motif containing 24 | -0.0257475 |
| RPL26 | ribosomal protein L26 | -0.0256363 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.025583 |
| USP15 | ubiquitin specific peptidase 15 | -0.0255604 |
| OSBPL9 | oxysterol binding protein-like 9 | -0.0254154 |
| PDGFC | platelet derived growth factor C | -0.02537 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.0249951 |
| RNF130 | ring finger protein 130 | -0.0245087 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0244883 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0242417 |
| RPL13A | ribosomal protein L13a | -0.0239994 |
| RPS3 | ribosomal protein S3 | -0.0237938 |
| NFIA | nuclear factor I/A | -0.0237373 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0234722 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0234518 |
| EVI5 | ecotropic viral integration site 5 | -0.0234411 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0232067 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0229758 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0229279 |
| GPATCH8 | G patch domain containing 8 | -0.0226947 |
| RBM33 | RNA binding motif protein 33 | -0.0226396 |
| AOPEP | aminopeptidase O (putative) | -0.0224393 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0223978 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0222554 |
| PHTF2 | putative homeodomain transcription factor 2 | -0.0221812 |
| RPL37A | ribosomal protein L37a | -0.0217094 |
| LDHA | lactate dehydrogenase A | -0.0215237 |
| ACTG1 | actin gamma 1 | -0.0207662 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0206376 |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 | -0.0205524 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0205092 |
| RPS13 | ribosomal protein S13 | -0.0204483 |
| MICU1 | mitochondrial calcium uptake 1 | -0.0203688 |
| UTRN | utrophin | -0.0203454 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0201917 |
| ATE1 | arginyltransferase 1 | -0.0201558 |
| SMIM44 | small integral membrane protein 44 | -0.020059 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0200517 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0199881 |
| SHISA3 | shisa family member 3 | -0.0199663 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0199542 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0198957 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0197339 |
| KIF13A | kinesin family member 13A | -0.0197172 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0195656 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0193844 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0193216 |
| COX5A | cytochrome c oxidase subunit Va | -0.0191935 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0191393 |
| GNS | glucosamine (N-acetyl)-6-sulfatase | -0.0189885 |
| PTMA | prothymosin, alpha | -0.0188685 |
| CTBP2 | C-terminal binding protein 2 | -0.0188094 |
