| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pasireotide (acetate) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pasireotide (acetate)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.249632 |
| NDRG1 | N-myc downstream regulated 1 | 0.0907041 |
| AHNAK | AHNAK nucleoprotein | 0.0495351 |
| ITGA6 | integrin, alpha 6 | 0.041362 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0370592 |
| OGA | O-GlcNAcase | 0.0355007 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0339472 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0319824 |
| MMP1 | matrix metallopeptidase 1 | 0.0313307 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0300208 |
| FLNB | filamin B, beta | 0.0291137 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0287748 |
| ASPH | aspartate beta-hydroxylase | 0.0287061 |
| HSPA8 | heat shock 70kDa protein 8 | 0.028676 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0277066 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.02725 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.0271819 |
| CAPRIN2 | caprin family member 2 | 0.0264447 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0258619 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0243821 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.024126 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0236183 |
| DSPP | dentin sialophosphoprotein | 0.0232552 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0232502 |
| XPO1 | exportin 1 | 0.0228199 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0226945 |
| ANLN | anillin, actin binding protein | 0.0225612 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0223966 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0220704 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0212099 |
| EFNA5 | ephrin-A5 | 0.0210787 |
| NEK7 | NIMA-related kinase 7 | 0.020435 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0199558 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0196319 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0187488 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0186501 |
| CCNY | cyclin Y | 0.0183916 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0182006 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0181223 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0180899 |
| CDK17 | cyclin-dependent kinase 17 | 0.0178154 |
| ARRDC3 | arrestin domain containing 3 | 0.0175876 |
| NPTN | neuroplastin | 0.0173639 |
| SDC4 | syndecan 4 | 0.0169115 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.0168991 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0166589 |
| FAM107B | family with sequence similarity 107, member B | 0.0164271 |
| KCMF1 | potassium channel modulatory factor 1 | 0.015997 |
| MYOF | myoferlin | 0.0157721 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0156602 |
| NCKAP1 | NCK-associated protein 1 | 0.0153888 |
| CORO1C | coronin, actin binding protein, 1C | 0.0151166 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0150653 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0146847 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0144018 |
| ITGB4 | integrin, beta 4 | 0.0143713 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0143676 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0142246 |
| PHF21A | PHD finger protein 21A | 0.0142069 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0140217 |
| MED13L | mediator complex subunit 13-like | 0.0138291 |
| FAM3C | family with sequence similarity 3, member C | 0.0137578 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0135829 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0135792 |
| ANO6 | anoctamin 6 | 0.0133189 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0130951 |
| HMGA2 | high mobility group AT-hook 2 | 0.0130878 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0130073 |
| ATP13A3 | ATPase type 13A3 | 0.0128794 |
| CEP170 | centrosomal protein 170kDa | 0.0127684 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0126538 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.012258 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.012182 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0121738 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0121591 |
| ZNF292 | zinc finger protein 292 | 0.0121468 |
| MKI67 | marker of proliferation Ki-67 | 0.0119606 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0116519 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0116058 |
| OPTN | optineurin | 0.0115076 |
| RNF145 | ring finger protein 145 | 0.0112651 |
| YAP1 | Yes-associated protein 1 | 0.0111462 |
| CCDC88A | coiled-coil domain containing 88A | 0.0111205 |
| H1-0 | H1.0 linker histone | 0.0110997 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0110864 |
| IRS2 | insulin receptor substrate 2 | 0.0110374 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0110265 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.0109948 |
| USP47 | ubiquitin specific peptidase 47 | 0.010913 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0108507 |
| ANKRD28 | ankyrin repeat domain 28 | 0.010849 |
| RALB | v-ral simian leukemia viral oncogene homolog B | 0.0108266 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0106656 |
| RPL3 | ribosomal protein L3 | 0.010655 |
| FAM13B | family with sequence similarity 13, member B | 0.0106546 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0105599 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0105453 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0104619 |
| RPS2 | ribosomal protein S2 | 0.0104295 |
| IL18 | interleukin 18 | 0.0103825 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.197749 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.174543 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.143761 |
| LAMB3 | laminin, beta 3 | -0.134468 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.130108 |
| TMSB10 | thymosin beta 10 | -0.122845 |
| FTL | ferritin, light polypeptide | -0.11734 |
| KLK10 | kallikrein-related peptidase 10 | -0.116091 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.113739 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.112164 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0960263 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0948697 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.0921991 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0895803 |
| B2M | beta-2-microglobulin | -0.0842436 |
| MXD1 | MAX dimerization protein 1 | -0.0734084 |
| TPM4 | tropomyosin 4 | -0.0710247 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0689585 |
| TXNRD1 | thioredoxin reductase 1 | -0.066736 |
| HMGA1 | high mobility group AT-hook 1 | -0.0655539 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0654 |
| RPL35A | ribosomal protein L35a | -0.0635733 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0631032 |
| EGR1 | early growth response 1 | -0.0571973 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0565964 |
| MCL1 | myeloid cell leukemia 1 | -0.0548907 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0544143 |
| RPL31 | ribosomal protein L31 | -0.054042 |
| RPL37A | ribosomal protein L37a | -0.0521909 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0517193 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0510319 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0504843 |
| RPS8 | ribosomal protein S8 | -0.0477355 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0476953 |
| PTMA | prothymosin, alpha | -0.0470681 |
| RPS13 | ribosomal protein S13 | -0.0457529 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0453335 |
| SP100 | SP100 nuclear antigen | -0.0443863 |
| LMO7 | LIM domain 7 | -0.0443502 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0436201 |
| ACTG1 | actin gamma 1 | -0.0427622 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0423854 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0423205 |
| CLMP | CXADR-like membrane protein | -0.0418131 |
| MUC17 | mucin 17, cell surface associated | -0.040865 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0404322 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0403036 |
| RPLP2 | ribosomal protein, large, P2 | -0.0401114 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0395199 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0393764 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0393322 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0386094 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0384672 |
| VIM | vimentin | -0.0384281 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0373669 |
| HDAC9 | histone deacetylase 9 | -0.0367675 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0367201 |
| PGK1 | phosphoglycerate kinase 1 | -0.0365469 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0358297 |
| DIAPH1 | diaphanous-related formin 1 | -0.0358057 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0348039 |
| RPLP1 | ribosomal protein, large, P1 | -0.0343966 |
| UPP1 | uridine phosphorylase 1 | -0.0342971 |
| RIOK3 | RIO kinase 3 | -0.0334706 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0332186 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0327454 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0323206 |
| RPS25 | ribosomal protein S25 | -0.0323155 |
| HM13 | histocompatibility (minor) 13 | -0.0321071 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0319993 |
| RPL9 | ribosomal protein L9 | -0.0318336 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0317988 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0317192 |
| FERMT1 | fermitin family member 1 | -0.0315682 |
| RPS24 | ribosomal protein S24 | -0.0311839 |
| MORF4L2 | mortality factor 4 like 2 | -0.0309829 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.030883 |
| RPS27A | ribosomal protein S27a | -0.030836 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0308082 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0307385 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0307348 |
| NPSR1 | neuropeptide S receptor 1 | -0.0306796 |
| RPS29 | ribosomal protein S29 | -0.0304433 |
| RPL23 | ribosomal protein L23 | -0.0301132 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0299188 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0297943 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0297537 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.029568 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0295656 |
| LAMA4 | laminin, alpha 4 | -0.0294635 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0291736 |
| HLA-A | major histocompatibility complex, class I, A | -0.0291223 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0289093 |
| PRSS3 | protease, serine, 3 | -0.0286545 |
| RPS16 | ribosomal protein S16 | -0.0284975 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0283232 |
| S100A11 | S100 calcium binding protein A11 | -0.0282235 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0282156 |
| VCL | vinculin | -0.0275855 |
| ARF4 | ADP-ribosylation factor 4 | -0.0275164 |
