| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pasireotide (acetate) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pasireotide (acetate)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL19 | ribosomal protein L19 | 0.208677 |
| RPL23 | ribosomal protein L23 | 0.138858 |
| VMP1 | vacuole membrane protein 1 | 0.116408 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0964505 |
| RPS6 | ribosomal protein S6 | 0.0804011 |
| VCP | valosin containing protein | 0.0733041 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0682349 |
| RPS3 | ribosomal protein S3 | 0.0643861 |
| RPL37A | ribosomal protein L37a | 0.0556516 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0540605 |
| RPS2 | ribosomal protein S2 | 0.0521858 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0521276 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0514184 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.050787 |
| TPM3 | tropomyosin 3 | 0.0506403 |
| MT2A | metallothionein 2A | 0.050634 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0501754 |
| FGB | fibrinogen beta chain | 0.0498921 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0486694 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0440141 |
| NTN4 | netrin 4 | 0.0435003 |
| MCL1 | myeloid cell leukemia 1 | 0.0427703 |
| RPS8 | ribosomal protein S8 | 0.0417422 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.041444 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0409569 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0403362 |
| GOLGB1 | golgin B1 | 0.0399359 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0391521 |
| SMYD3 | SET and MYND domain containing 3 | 0.0384206 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0376292 |
| RPL37 | ribosomal protein L37 | 0.0374703 |
| YBX1 | Y box binding protein 1 | 0.0374139 |
| RPS12 | ribosomal protein S12 | 0.0373871 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 0.0372775 |
| PDLIM5 | PDZ and LIM domain 5 | 0.036389 |
| AHNAK | AHNAK nucleoprotein | 0.0361282 |
| VEGFA | vascular endothelial growth factor A | 0.0361118 |
| EXT1 | exostosin glycosyltransferase 1 | 0.036013 |
| CDK12 | cyclin-dependent kinase 12 | 0.0347548 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0347185 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0347064 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0340335 |
| DSPP | dentin sialophosphoprotein | 0.032338 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0322822 |
| KIF5B | kinesin family member 5B | 0.0320779 |
| INTS6 | integrator complex subunit 6 | 0.0320156 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0311952 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0311015 |
| APP | amyloid beta (A4) precursor protein | 0.0310984 |
| RPL12 | ribosomal protein L12 | 0.0306794 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0299312 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0297205 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0295423 |
| RPL34 | ribosomal protein L34 | 0.0294814 |
| CENPF | centromere protein F, 350/400kDa | 0.0294697 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0291287 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0286618 |
| STIP1 | stress-induced phosphoprotein 1 | 0.0285584 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0283326 |
| PNN | pinin, desmosome associated protein | 0.0280935 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0279405 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0278804 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0277004 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0276041 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0270123 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0268351 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0268133 |
| DUSP16 | dual specificity phosphatase 16 | 0.0267935 |
| RPS19 | ribosomal protein S19 | 0.0267569 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0263024 |
| RPL26 | ribosomal protein L26 | 0.026224 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0262162 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0259724 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0258948 |
| MED13L | mediator complex subunit 13-like | 0.025535 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0250811 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.025027 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0250016 |
| CHD8 | chromodomain helicase DNA binding protein 8 | 0.0245968 |
| RPS27A | ribosomal protein S27a | 0.0245048 |
| SFPQ | splicing factor proline/glutamine-rich | 0.024239 |
| FNBP1L | formin binding protein 1-like | 0.0242318 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0237891 |
| SLK | STE20-like kinase | 0.023727 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0237233 |
| OGA | O-GlcNAcase | 0.0235688 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0233994 |
| USP15 | ubiquitin specific peptidase 15 | 0.0232992 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0232596 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0232357 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0231657 |
| RPL13A | ribosomal protein L13a | 0.023163 |
| RBM39 | RNA binding motif protein 39 | 0.0231291 |
| SYTL2 | synaptotagmin-like 2 | 0.0231027 |
| USP47 | ubiquitin specific peptidase 47 | 0.0228622 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0225389 |
| RPL36 | ribosomal protein L36 | 0.0224587 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0223432 |
| RPL3 | ribosomal protein L3 | 0.0222418 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0221686 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.250198 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0832708 |
| TMEM123 | transmembrane protein 123 | -0.0666445 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0650353 |
| LASP1 | LIM and SH3 protein 1 | -0.0643962 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | -0.0603045 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0577617 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0548375 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.052673 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0526169 |
| MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | -0.051183 |
| CCND1 | cyclin D1 | -0.0496822 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0484435 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0469834 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0465713 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0459969 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0457808 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0456567 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0451961 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0437311 |
| ACTG1 | actin gamma 1 | -0.043494 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0392098 |
| LDHA | lactate dehydrogenase A | -0.0384336 |
| CCNI | cyclin I | -0.037328 |
| FASN | fatty acid synthase | -0.0356662 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0340214 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0339563 |
| TUBA1B | tubulin, alpha 1b | -0.0335431 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0331664 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0329659 |
| CEP250 | centrosomal protein 250kDa | -0.0325551 |
| ZNF652 | zinc finger protein 652 | -0.031771 |
| POTEF | POTE ankyrin domain family, member F | -0.03123 |
| PTMA | prothymosin, alpha | -0.0300955 |
| TMEM165 | transmembrane protein 165 | -0.0293733 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0288617 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0285808 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0283837 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0282703 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.027655 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0275524 |
| CD164 | CD164 molecule, sialomucin | -0.0270535 |
| RPLP0 | ribosomal protein, large, P0 | -0.0267184 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0265585 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0262133 |
| FADS2 | fatty acid desaturase 2 | -0.0261885 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0261435 |
| DENND1A | DENN/MADD domain containing 1A | -0.0250481 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0244473 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0242722 |
| TPM4 | tropomyosin 4 | -0.0234307 |
| COX8A | cytochrome c oxidase subunit VIIIA (ubiquitous) | -0.0233641 |
| MGP | matrix Gla protein | -0.02331 |
| KRT19 | keratin 19, type I | -0.0230247 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0226986 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0226227 |
| BCAS1 | breast carcinoma amplified sequence 1 | -0.022137 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0220593 |
| NCOA6 | nuclear receptor coactivator 6 | -0.0212176 |
| PERP | PERP, TP53 apoptosis effector | -0.0210424 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0208789 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0207097 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0205885 |
| TUBB | tubulin, beta class I | -0.0205263 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0205146 |
| CLMN | calmin (calponin-like, transmembrane) | -0.0205116 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0204929 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0203293 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0200307 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0198412 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.0197092 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0196409 |
| WDR45B | WD repeat domain 45B | -0.0196121 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0193363 |
| CD24 | CD24 molecule | -0.0193173 |
| PCBP2 | poly(rC) binding protein 2 | -0.0192094 |
| DENND1B | DENN/MADD domain containing 1B | -0.0191523 |
| TMSB4X | thymosin beta 4, X-linked | -0.0191495 |
| FDPS | farnesyl diphosphate synthase | -0.0191146 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0191115 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0190817 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 | -0.0190804 |
| ARF1 | ADP-ribosylation factor 1 | -0.0188405 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0185598 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0185212 |
| GSE1 | Gse1 coiled-coil protein | -0.0184691 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0182525 |
| BBX | bobby sox homolog (Drosophila) | -0.0181898 |
| NAPG | N-ethylmaleimide-sensitive factor attachment protein, gamma | -0.0181738 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0180159 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0179759 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0179292 |
| PSMB3 | proteasome (prosome, macropain) subunit, beta type, 3 | -0.0179093 |
| TOB1 | transducer of ERBB2, 1 | -0.0178449 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0177965 |
| ENO1 | enolase 1, (alpha) | -0.0173676 |
| TMEM135 | transmembrane protein 135 | -0.0173355 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | -0.0173045 |
| TPCN1 | two pore segment channel 1 | -0.0172307 |
| WASF2 | WAS protein family, member 2 | -0.0170133 |
