| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pasireotide (acetate) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pasireotide (acetate)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.21723 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0949659 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0891767 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0862771 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0739726 |
| TXNIP | thioredoxin interacting protein | 0.0691484 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0688008 |
| MYO1E | myosin IE | 0.0684947 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0675096 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0663488 |
| B2M | beta-2-microglobulin | 0.0660646 |
| EZR | ezrin | 0.0585772 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.058375 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0578327 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0562402 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.05598 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0545585 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0544132 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0537065 |
| MEIS2 | Meis homeobox 2 | 0.050564 |
| EFNB2 | ephrin-B2 | 0.0501327 |
| VMP1 | vacuole membrane protein 1 | 0.0498894 |
| MCU | mitochondrial calcium uniporter | 0.0476874 |
| PHF3 | PHD finger protein 3 | 0.0475961 |
| DSPP | dentin sialophosphoprotein | 0.047214 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0470254 |
| KLF6 | Kruppel-like factor 6 | 0.0461884 |
| SQSTM1 | sequestosome 1 | 0.0461794 |
| SMAD3 | SMAD family member 3 | 0.0458066 |
| IFNGR1 | interferon gamma receptor 1 | 0.0457828 |
| APOL1 | apolipoprotein L, 1 | 0.044644 |
| ABHD2 | abhydrolase domain containing 2 | 0.04429 |
| SDC4 | syndecan 4 | 0.0441209 |
| TRIM2 | tripartite motif containing 2 | 0.0437488 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0435756 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0432325 |
| LIMA1 | LIM domain and actin binding 1 | 0.0431523 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0427688 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0413482 |
| PDZD8 | PDZ domain containing 8 | 0.040883 |
| GOLGB1 | golgin B1 | 0.0402322 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0401386 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0400756 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0400431 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0399993 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0395557 |
| USP53 | ubiquitin specific peptidase 53 | 0.039026 |
| STK24 | serine/threonine kinase 24 | 0.0387245 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0384308 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0381078 |
| ANXA2 | annexin A2 | 0.0377127 |
| SLK | STE20-like kinase | 0.0375367 |
| LCN2 | lipocalin 2 | 0.0372724 |
| RRBP1 | ribosome binding protein 1 | 0.0368927 |
| ITGA6 | integrin, alpha 6 | 0.0365893 |
| PRKCA | protein kinase C, alpha | 0.0365206 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0364178 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0362998 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.036255 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0357035 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0355843 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0354057 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0349843 |
| JUN | jun proto-oncogene | 0.0340673 |
| KIAA1217 | KIAA1217 | 0.0340296 |
| SEPTIN9 | septin 9 | 0.0339135 |
| JMJD1C | jumonji domain containing 1C | 0.0330296 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0328866 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0324334 |
| MYO10 | myosin X | 0.0323304 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0315175 |
| FNIP2 | folliculin interacting protein 2 | 0.0313948 |
| MSI2 | musashi RNA-binding protein 2 | 0.0312742 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0311553 |
| DST | dystonin | 0.0310231 |
| ACTN4 | actinin, alpha 4 | 0.0309229 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0308862 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.030838 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0307669 |
| DUSP10 | dual specificity phosphatase 10 | 0.0304591 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0301868 |
| ATP10B | ATPase, class V, type 10B | 0.0300271 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0294901 |
| USP54 | ubiquitin specific peptidase 54 | 0.0294788 |
| MED13L | mediator complex subunit 13-like | 0.029431 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0294181 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0293262 |
| BCL2L1 | BCL2-like 1 | 0.0290949 |
| KYNU | kynureninase | 0.0290917 |
| RND3 | Rho family GTPase 3 | 0.0288903 |
| ETV6 | ets variant 6 | 0.0286549 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0286337 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0280735 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0280553 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0279846 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0275452 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0268022 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0267191 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0266394 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0265085 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.124131 |
| LYZ | lysozyme | -0.104671 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0882596 |
| FTL | ferritin, light polypeptide | -0.0794435 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0733526 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0542934 |
| RPL35A | ribosomal protein L35a | -0.05121 |
| SP100 | SP100 nuclear antigen | -0.0463868 |
| TMSB10 | thymosin beta 10 | -0.0455254 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0454102 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.04361 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0423024 |
| RPS6 | ribosomal protein S6 | -0.0409294 |
| RPS13 | ribosomal protein S13 | -0.0392286 |
| RPS29 | ribosomal protein S29 | -0.0388032 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0376174 |
| VIM | vimentin | -0.0360428 |
| MX1 | MX dynamin-like GTPase 1 | -0.0359427 |
| HLA-B | major histocompatibility complex, class I, B | -0.0356485 |
| RPL31 | ribosomal protein L31 | -0.0354257 |
| RPLP0 | ribosomal protein, large, P0 | -0.0349629 |
| RPS16 | ribosomal protein S16 | -0.0343964 |
| NPSR1 | neuropeptide S receptor 1 | -0.033989 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0336373 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0335627 |
| RPL9 | ribosomal protein L9 | -0.0333279 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0328495 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0322714 |
| MUC20 | mucin 20, cell surface associated | -0.0319533 |
| RPLP1 | ribosomal protein, large, P1 | -0.0319321 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0318454 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0316936 |
| RPS20 | ribosomal protein S20 | -0.0311576 |
| RIGI | RNA sensor RIG-I | -0.0309259 |
| RPS3 | ribosomal protein S3 | -0.0307862 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0306359 |
| RPS24 | ribosomal protein S24 | -0.0292848 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.028818 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0285011 |
| RPL38 | ribosomal protein L38 | -0.0284224 |
| GNAS | GNAS complex locus | -0.0283595 |
| TNS4 | tensin 4 | -0.0279719 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0278015 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0273275 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0269225 |
| PARD3 | par-3 family cell polarity regulator | -0.0263823 |
| NUP58 | nucleoporin 58 | -0.0252638 |
| RPS8 | ribosomal protein S8 | -0.0252152 |
| RPL37A | ribosomal protein L37a | -0.0252042 |
| HM13 | histocompatibility (minor) 13 | -0.0251507 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0244263 |
| HLA-C | major histocompatibility complex, class I, C | -0.0243583 |
| RPL23 | ribosomal protein L23 | -0.0242423 |
| RPS27A | ribosomal protein S27a | -0.0239735 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0238101 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0235855 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0234961 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.023103 |
| ACTG1 | actin gamma 1 | -0.0229496 |
| DIAPH3 | diaphanous-related formin 3 | -0.0226794 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0225296 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.022418 |
| LAP3 | leucine aminopeptidase 3 | -0.022227 |
| RPL36A | ribosomal protein L36a | -0.0221554 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0221099 |
| RPS25 | ribosomal protein S25 | -0.0220997 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0219501 |
| RPS14 | ribosomal protein S14 | -0.0218365 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0218307 |
| PLSCR1 | phospholipid scramblase 1 | -0.0217978 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0210394 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0209704 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0204953 |
| SSR1 | signal sequence receptor, alpha | -0.0204503 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0204248 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0202704 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0202396 |
| PMP22 | peripheral myelin protein 22 | -0.0202309 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0201872 |
| S100A6 | S100 calcium binding protein A6 | -0.0200951 |
| ENO1 | enolase 1, (alpha) | -0.0199958 |
| BRCA2 | breast cancer 2, early onset | -0.0199396 |
| RPS12 | ribosomal protein S12 | -0.0197471 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0196389 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0195044 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0190486 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0188556 |
| FN1 | fibronectin 1 | -0.0185901 |
| RPS23 | ribosomal protein S23 | -0.0185348 |
| LDHA | lactate dehydrogenase A | -0.0185296 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0184691 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0184498 |
| RNF213 | ring finger protein 213 | -0.018398 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0182802 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0182776 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0182752 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0182075 |
| AFMID | arylformamidase | -0.0181585 |
| CSTB | cystatin B (stefin B) | -0.0180957 |
| RPS11 | ribosomal protein S11 | -0.0179879 |