| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pasireotide (acetate) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pasireotide (acetate)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.256778 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.158235 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.137232 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.112641 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0964584 |
| AHNAK | AHNAK nucleoprotein | 0.0954882 |
| ASPH | aspartate beta-hydroxylase | 0.0898715 |
| MKI67 | marker of proliferation Ki-67 | 0.0889591 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0875453 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0837918 |
| DST | dystonin | 0.0716975 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0707627 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0693971 |
| CANX | calnexin | 0.0680971 |
| CENPF | centromere protein F, 350/400kDa | 0.0540904 |
| NDRG1 | N-myc downstream regulated 1 | 0.0500032 |
| RPS6 | ribosomal protein S6 | 0.0477591 |
| GOLGB1 | golgin B1 | 0.0455312 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0424445 |
| CD44 | CD44 molecule (Indian blood group) | 0.0421247 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0396319 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0387661 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0378688 |
| APP | amyloid beta (A4) precursor protein | 0.0372645 |
| RPS8 | ribosomal protein S8 | 0.0371773 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0371529 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0362654 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0346753 |
| VEGFA | vascular endothelial growth factor A | 0.0339727 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0338535 |
| STC1 | stanniocalcin 1 | 0.0333747 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0330528 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0322525 |
| ANXA2 | annexin A2 | 0.0319477 |
| TPM3 | tropomyosin 3 | 0.0313403 |
| B2M | beta-2-microglobulin | 0.0307694 |
| SFTPA2 | surfactant protein A2 | 0.0307357 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0299453 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0298769 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0293917 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0293395 |
| YBX1 | Y box binding protein 1 | 0.029292 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0291583 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0291269 |
| ENO1 | enolase 1, (alpha) | 0.0283982 |
| PRELID2 | PRELI domain containing 2 | 0.0280606 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0279166 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.027515 |
| CALR | calreticulin | 0.0265646 |
| H1-4 | H1.4 linker histone, cluster member | 0.0265568 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0264398 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0263794 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0257211 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0255663 |
| TXNIP | thioredoxin interacting protein | 0.0255436 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0254483 |
| PHF3 | PHD finger protein 3 | 0.0253674 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0251769 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0248074 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0235865 |
| JUN | jun proto-oncogene | 0.0235053 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0233716 |
| INHBA | inhibin, beta A | 0.0222753 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.02219 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0220927 |
| RPL3 | ribosomal protein L3 | 0.0217722 |
| MT2A | metallothionein 2A | 0.0215044 |
| CALN1 | calneuron 1 | 0.0212836 |
| GOLGA4 | golgin A4 | 0.0212346 |
| PKM | pyruvate kinase, muscle | 0.0211097 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0208659 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0208292 |
| LOXL2 | lysyl oxidase-like 2 | 0.0207973 |
| HDAC9 | histone deacetylase 9 | 0.0206986 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.020697 |
| FAM13A | family with sequence similarity 13, member A | 0.0204185 |
| RACK1 | receptor for activated C kinase 1 | 0.0202799 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0197247 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0197025 |
| RPS2 | ribosomal protein S2 | 0.0195795 |
| TPX2 | TPX2, microtubule-associated | 0.0195256 |
| KYNU | kynureninase | 0.019456 |
| CLTC | clathrin, heavy chain (Hc) | 0.0190769 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0189619 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0189379 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0187817 |
| VCL | vinculin | 0.0184618 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0183807 |
| GLG1 | golgi glycoprotein 1 | 0.0182572 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0180982 |
| OGA | O-GlcNAcase | 0.0178585 |
| EMP1 | epithelial membrane protein 1 | 0.0177195 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0176574 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0176298 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.017625 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0174961 |
| RBM39 | RNA binding motif protein 39 | 0.0174878 |
| RPL4 | ribosomal protein L4 | 0.0174726 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0174417 |
| HDLBP | high density lipoprotein binding protein | 0.0173633 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NALF1 | NALCN channel auxiliary factor 1 | -0.0737633 |
| TMSB10 | thymosin beta 10 | -0.0644491 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0443981 |
| POTEF | POTE ankyrin domain family, member F | -0.0405446 |
| IGF2 | insulin-like growth factor 2 | -0.0393247 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0323674 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0281901 |
| HMGA1 | high mobility group AT-hook 1 | -0.0200142 |
| ACTG1 | actin gamma 1 | -0.0199588 |
| TNS3 | tensin 3 | -0.0199498 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0198215 |
| CALD1 | caldesmon 1 | -0.0196665 |
| NAV3 | neuron navigator 3 | -0.0195783 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0182673 |
| NAV1 | neuron navigator 1 | -0.0180249 |
| S100A6 | S100 calcium binding protein A6 | -0.0171815 |
| EGFR | epidermal growth factor receptor | -0.0169676 |
| PTK2 | protein tyrosine kinase 2 | -0.0167527 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0158331 |
| LYPD6B | LY6/PLAUR domain containing 6B | -0.0158116 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0157545 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0156395 |
| TENM3 | teneurin transmembrane protein 3 | -0.015309 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0147419 |
| TUBA1C | tubulin, alpha 1c | -0.0147259 |
| TUBA1B | tubulin, alpha 1b | -0.0146118 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.013599 |
| CTSD | cathepsin D | -0.0135623 |
| CCND1 | cyclin D1 | -0.0132853 |
| CD151 | CD151 molecule (Raph blood group) | -0.0127058 |
| SBF2 | SET binding factor 2 | -0.0123936 |
| TTYH3 | tweety family member 3 | -0.0116829 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0116717 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0115534 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.0114806 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0113345 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0113094 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0111752 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.011083 |
| NAV2 | neuron navigator 2 | -0.0110215 |
| COMMD10 | COMM domain containing 10 | -0.0110089 |
| AGRN | agrin | -0.0108324 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.010701 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | -0.0106895 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0105893 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0105034 |
| CLMP | CXADR-like membrane protein | -0.0103935 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0101423 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00999929 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.00996582 |
| GPC6 | glypican 6 | -0.00988213 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.00980845 |
| TAPBP | TAP binding protein (tapasin) | -0.00976038 |
| DTNA | dystrobrevin, alpha | -0.00975944 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.00963885 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.00963598 |
| CAPNS1 | calpain, small subunit 1 | -0.00952906 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.00938003 |
| RPS24 | ribosomal protein S24 | -0.00931242 |
| VDAC1 | voltage-dependent anion channel 1 | -0.00924978 |
| KPNB1 | karyopherin (importin) beta 1 | -0.00924781 |
| RPL27A | ribosomal protein L27a | -0.00918791 |
| ZNF804A | zinc finger protein 804A | -0.00917926 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.00917434 |
| TMEM165 | transmembrane protein 165 | -0.00915408 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.00911279 |
| CSNK1E | casein kinase 1, epsilon | -0.00903929 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.00903618 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.00903604 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00893745 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.00893561 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | -0.00889632 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.00884868 |
| AOAH | acyloxyacyl hydrolase (neutrophil) | -0.0088363 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0088148 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0088109 |
| AXL | AXL receptor tyrosine kinase | -0.00878284 |
| DIAPH3 | diaphanous-related formin 3 | -0.008777 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.00876527 |
| IL7R | interleukin 7 receptor | -0.00876434 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.00872343 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.00871615 |
| ATN1 | atrophin 1 | -0.00871462 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.00860592 |
| PRR16 | proline rich 16 | -0.0084716 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.00830466 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.00828723 |
| CCDC91 | coiled-coil domain containing 91 | -0.008204 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.00819995 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | -0.00813755 |
| ERLEC1 | endoplasmic reticulum lectin 1 | -0.0081043 |
| CDK14 | cyclin-dependent kinase 14 | -0.00806906 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.00804384 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0080188 |
| OLA1 | Obg-like ATPase 1 | -0.00798986 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.00794481 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.00793548 |
| ZBTB7A | zinc finger and BTB domain containing 7A | -0.00792693 |
| ZDHHC17 | zinc finger, DHHC-type containing 17 | -0.00792306 |
| SCFD1 | sec1 family domain containing 1 | -0.00791437 |
