| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pasireotide (acetate) perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pasireotide (acetate)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS6 | ribosomal protein S6 | 0.118741 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.110618 |
| MKI67 | marker of proliferation Ki-67 | 0.109324 |
| MT2A | metallothionein 2A | 0.106655 |
| ASPH | aspartate beta-hydroxylase | 0.10532 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0916341 |
| GOLGA4 | golgin A4 | 0.0897844 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0835278 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.083474 |
| TPM3 | tropomyosin 3 | 0.0812398 |
| GOLGB1 | golgin B1 | 0.068363 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0650745 |
| YBX1 | Y box binding protein 1 | 0.0644016 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0625166 |
| RPS2 | ribosomal protein S2 | 0.0623427 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0608177 |
| CENPF | centromere protein F, 350/400kDa | 0.0586085 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0573163 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0565888 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0546447 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0540073 |
| RPL3 | ribosomal protein L3 | 0.0521517 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0512601 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0510695 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0509596 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0508673 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0487556 |
| TMF1 | TATA element modulatory factor 1 | 0.0487048 |
| BRD2 | bromodomain containing 2 | 0.0485362 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0478849 |
| DSPP | dentin sialophosphoprotein | 0.0457706 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0453805 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0442945 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0433504 |
| SNX9 | sorting nexin 9 | 0.0426887 |
| VMP1 | vacuole membrane protein 1 | 0.041292 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0409019 |
| RPS12 | ribosomal protein S12 | 0.0408837 |
| JMJD1C | jumonji domain containing 1C | 0.039485 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0393526 |
| RUNX1 | runt-related transcription factor 1 | 0.0389679 |
| H1-4 | H1.4 linker histone, cluster member | 0.0384376 |
| DSG2 | desmoglein 2 | 0.0382632 |
| SET | SET nuclear proto-oncogene | 0.0381641 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0377066 |
| RPS8 | ribosomal protein S8 | 0.0371186 |
| EZR | ezrin | 0.0371015 |
| NDRG1 | N-myc downstream regulated 1 | 0.0355094 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0349623 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0336259 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0334638 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0331854 |
| LAMB3 | laminin, beta 3 | 0.0323098 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0320782 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.03198 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0318301 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0306294 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0306277 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0304873 |
| CDCP1 | CUB domain containing protein 1 | 0.0302214 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0281254 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0280443 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0272995 |
| FNIP1 | folliculin interacting protein 1 | 0.0272215 |
| RPL14 | ribosomal protein L14 | 0.0266497 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0265865 |
| B2M | beta-2-microglobulin | 0.0265624 |
| KIF5B | kinesin family member 5B | 0.0261555 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0261255 |
| RPL7A | ribosomal protein L7a | 0.0254096 |
| SPAG9 | sperm associated antigen 9 | 0.0253595 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0253185 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.02514 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0249903 |
| RPL37A | ribosomal protein L37a | 0.0249833 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0249711 |
| ARF4 | ADP-ribosylation factor 4 | 0.0249561 |
| SETD5 | SET domain containing 5 | 0.024944 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0248763 |
| RPS3 | ribosomal protein S3 | 0.0247971 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0247617 |
| TXNRD1 | thioredoxin reductase 1 | 0.0246492 |
| SFTPA2 | surfactant protein A2 | 0.0244228 |
| OPTN | optineurin | 0.0241715 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.024117 |
| HELZ | helicase with zinc finger | 0.0237334 |
| ANO6 | anoctamin 6 | 0.0236518 |
| MYO6 | myosin VI | 0.0231981 |
| TPD52 | tumor protein D52 | 0.023121 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0230614 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0230385 |
| APP | amyloid beta (A4) precursor protein | 0.0230364 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0229064 |
| BBX | bobby sox homolog (Drosophila) | 0.0228818 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0226698 |
| VEGFA | vascular endothelial growth factor A | 0.0226054 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0224312 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0223555 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0223493 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0223484 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.131514 |
| TMSB10 | thymosin beta 10 | -0.122457 |
| ACTG1 | actin gamma 1 | -0.115768 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.101095 |
| FLNA | filamin A, alpha | -0.087279 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0739598 |
| PAX8 | paired box 8 | -0.0697364 |
| CCND1 | cyclin D1 | -0.0667724 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0643887 |
| AHNAK | AHNAK nucleoprotein | -0.0623429 |
| LDHA | lactate dehydrogenase A | -0.060662 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0588411 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0566513 |
| ACTN4 | actinin, alpha 4 | -0.0558643 |
| ITGB8 | integrin, beta 8 | -0.0552223 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0515064 |
| EGFR | epidermal growth factor receptor | -0.0485691 |
| H1-0 | H1.0 linker histone | -0.0483198 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0474048 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0472992 |
| HMGA2 | high mobility group AT-hook 2 | -0.0471401 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.046545 |
| PRELID2 | PRELI domain containing 2 | -0.0464237 |
| TUBB | tubulin, beta class I | -0.0463797 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.0454799 |
| KRT7 | keratin 7, type II | -0.0451149 |
| RPS24 | ribosomal protein S24 | -0.0445425 |
| ATG7 | autophagy related 7 | -0.043905 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | -0.0437435 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0437024 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0428846 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0419281 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.041185 |
| ARF1 | ADP-ribosylation factor 1 | -0.040555 |
| RPL35A | ribosomal protein L35a | -0.0400018 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0368719 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0363256 |
| RAB7A | RAB7A, member RAS oncogene family | -0.036125 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0359569 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0353185 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0349515 |
| WWOX | WW domain containing oxidoreductase | -0.034944 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0348056 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0341733 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0332608 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0329834 |
| HMGA1 | high mobility group AT-hook 1 | -0.032838 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.032815 |
| ENOSF1 | enolase superfamily member 1 | -0.0319964 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 | -0.0315869 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0310113 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0308733 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0303789 |
| FOXK1 | forkhead box K1 | -0.0303744 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0302528 |
| MYOF | myoferlin | -0.0301565 |
| KLF6 | Kruppel-like factor 6 | -0.0297508 |
| PCED1B | PC-esterase domain containing 1B | -0.0295166 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0291835 |
| POU5F1 | POU class 5 homeobox 1 | -0.0288943 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0281494 |
| CD44 | CD44 molecule (Indian blood group) | -0.0281018 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.027747 |
| TMSB4X | thymosin beta 4, X-linked | -0.0275384 |
| CLDN1 | claudin 1 | -0.027092 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0270818 |
| KRT19 | keratin 19, type I | -0.0268764 |
| PLEC | plectin | -0.025901 |
| HMGB1 | high mobility group box 1 | -0.0257872 |
| BICC1 | BicC family RNA binding protein 1 | -0.0257722 |
| S100A4 | S100 calcium binding protein A4 | -0.0254422 |
| NF1 | neurofibromin 1 | -0.025361 |
| RASA3 | RAS p21 protein activator 3 | -0.0253179 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0251921 |
| TUBA1B | tubulin, alpha 1b | -0.0250505 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | -0.0247614 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0246037 |
| PGK1 | phosphoglycerate kinase 1 | -0.0245806 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0245274 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0244109 |
| KAZN | kazrin, periplakin interacting protein | -0.0241948 |
| TMEM123 | transmembrane protein 123 | -0.0241337 |
| TNS3 | tensin 3 | -0.0240371 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0237285 |
| SPATA13 | spermatogenesis associated 13 | -0.0237277 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0235426 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0234068 |
| WDR45B | WD repeat domain 45B | -0.0232624 |
| CAPNS1 | calpain, small subunit 1 | -0.0232241 |
| MGLL | monoglyceride lipase | -0.0229523 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0228289 |
| ANXA2 | annexin A2 | -0.0227439 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0225767 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0222669 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0217643 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.02152 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0214857 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -0.0214808 |
| ABLIM1 | actin binding LIM protein 1 | -0.0214619 |
| MGMT | O-6-methylguanine-DNA methyltransferase | -0.0211473 |
