| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pasireotide (acetate) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pasireotide (acetate)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.302871 |
| RPS6 | ribosomal protein S6 | 0.197775 |
| MT2A | metallothionein 2A | 0.145722 |
| AHNAK | AHNAK nucleoprotein | 0.129963 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0944505 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0936533 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0852637 |
| RPS8 | ribosomal protein S8 | 0.0829856 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0759545 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0749379 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0711013 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0694599 |
| RPS19 | ribosomal protein S19 | 0.0691483 |
| CENPF | centromere protein F, 350/400kDa | 0.068468 |
| ASPH | aspartate beta-hydroxylase | 0.0681759 |
| LAMB3 | laminin, beta 3 | 0.0663288 |
| MKI67 | marker of proliferation Ki-67 | 0.0644687 |
| YBX1 | Y box binding protein 1 | 0.0625563 |
| GOLGB1 | golgin B1 | 0.0613144 |
| RPL19 | ribosomal protein L19 | 0.0585229 |
| PLEC | plectin | 0.0553649 |
| RPL34 | ribosomal protein L34 | 0.0553076 |
| RPL12 | ribosomal protein L12 | 0.0552159 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0540143 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.053811 |
| RPS12 | ribosomal protein S12 | 0.0520454 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0520398 |
| FN1 | fibronectin 1 | 0.0516491 |
| SFTPA2 | surfactant protein A2 | 0.0511749 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.050641 |
| RRBP1 | ribosome binding protein 1 | 0.0503494 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0497042 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0476593 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0473506 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0466354 |
| RPL37A | ribosomal protein L37a | 0.0449543 |
| DNMBP | dynamin binding protein | 0.0433222 |
| VEGFA | vascular endothelial growth factor A | 0.0426625 |
| RPS2 | ribosomal protein S2 | 0.0418119 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0413539 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0400649 |
| RPL3 | ribosomal protein L3 | 0.039745 |
| GOLGA4 | golgin A4 | 0.0394051 |
| H1-4 | H1.4 linker histone, cluster member | 0.0391487 |
| RPS17 | ribosomal protein S17 | 0.038883 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0384157 |
| DUSP6 | dual specificity phosphatase 6 | 0.0384107 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0377561 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0373523 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0372527 |
| RPS4X | ribosomal protein S4, X-linked | 0.0372079 |
| TPM3 | tropomyosin 3 | 0.0369519 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0367929 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0367583 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0367322 |
| RPS3 | ribosomal protein S3 | 0.0357267 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0356646 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0352772 |
| RPL32 | ribosomal protein L32 | 0.0352302 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0351635 |
| DST | dystonin | 0.0349807 |
| NDRG1 | N-myc downstream regulated 1 | 0.0346698 |
| RPLP2 | ribosomal protein, large, P2 | 0.0339046 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0335731 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0330818 |
| RPL11 | ribosomal protein L11 | 0.0325742 |
| RPL8 | ribosomal protein L8 | 0.0320411 |
| CD44 | CD44 molecule (Indian blood group) | 0.0312793 |
| RRM2 | ribonucleotide reductase M2 | 0.0312688 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0307891 |
| RPL36 | ribosomal protein L36 | 0.0307186 |
| RPS27 | ribosomal protein S27 | 0.0306391 |
| RPL26 | ribosomal protein L26 | 0.0306311 |
| MT1E | metallothionein 1E | 0.0305286 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0305116 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.0304968 |
| MCL1 | myeloid cell leukemia 1 | 0.0303422 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0302298 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0301901 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0299859 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0295776 |
| RPL23 | ribosomal protein L23 | 0.0293831 |
| MAP1B | microtubule-associated protein 1B | 0.0291763 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0291095 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0286961 |
| INHBA | inhibin, beta A | 0.0285607 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0284273 |
| DSPP | dentin sialophosphoprotein | 0.0284229 |
| RPLP1 | ribosomal protein, large, P1 | 0.0281845 |
| CAVIN1 | caveolae associated protein 1 | 0.0276724 |
| DSG2 | desmoglein 2 | 0.027572 |
| RPL37 | ribosomal protein L37 | 0.0271304 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.026999 |
| RPL31 | ribosomal protein L31 | 0.0267426 |
| PHF3 | PHD finger protein 3 | 0.0266451 |
| TPI1 | triosephosphate isomerase 1 | 0.0265072 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.026356 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0259695 |
| MCFD2 | multiple coagulation factor deficiency 2 | 0.0258185 |
| TMSB10 | thymosin beta 10 | 0.025717 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.213703 |
| VIM | vimentin | -0.186823 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.107798 |
| CDH13 | cadherin 13 | -0.0997617 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0866224 |
| FNDC3B | fibronectin type III domain containing 3B | -0.07945 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0593284 |
| COL5A1 | collagen, type V, alpha 1 | -0.0583729 |
| LDHA | lactate dehydrogenase A | -0.054234 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0526379 |
| GLIS3 | GLIS family zinc finger 3 | -0.0518654 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0515333 |
| ENO1 | enolase 1, (alpha) | -0.051437 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0512077 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0511864 |
| TENM2 | teneurin transmembrane protein 2 | -0.0505099 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0492924 |
| NAV1 | neuron navigator 1 | -0.0473456 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0461685 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0449784 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0439397 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0425082 |
| DIAPH2 | diaphanous-related formin 2 | -0.0398716 |
| PTK2 | protein tyrosine kinase 2 | -0.0387293 |
| SBF2 | SET binding factor 2 | -0.0379344 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0371898 |
| CLMP | CXADR-like membrane protein | -0.0363551 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0362889 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.035638 |
| CCND1 | cyclin D1 | -0.0353575 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0340567 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0337063 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0335438 |
| USP34 | ubiquitin specific peptidase 34 | -0.0334883 |
| UBC | ubiquitin C | -0.0330976 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0326469 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0325949 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0323938 |
| RNF24 | ring finger protein 24 | -0.031694 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0316355 |
| DTNA | dystrobrevin, alpha | -0.031593 |
| TMEM165 | transmembrane protein 165 | -0.031411 |
| POTEF | POTE ankyrin domain family, member F | -0.03092 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0304641 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0300378 |
| TFG | TRK-fused gene | -0.0298635 |
| AGRN | agrin | -0.02982 |
| PGK1 | phosphoglycerate kinase 1 | -0.0297403 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0294226 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0294204 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0293337 |
| LOX | lysyl oxidase | -0.0292255 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0286412 |
| ACTG1 | actin gamma 1 | -0.0285824 |
| TPM1 | tropomyosin 1 (alpha) | -0.0282827 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0281112 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0279465 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0278722 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0277385 |
| NGLY1 | N-glycanase 1 | -0.0272459 |
| WDR45B | WD repeat domain 45B | -0.0270078 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0267337 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0266698 |
| NF1 | neurofibromin 1 | -0.0265521 |
| CALU | calumenin | -0.0262288 |
| PKM | pyruvate kinase, muscle | -0.0259759 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0250969 |
| ZNF148 | zinc finger protein 148 | -0.0250618 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0248347 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0247709 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0245614 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0245344 |
| PCBP2 | poly(rC) binding protein 2 | -0.0245089 |
| EGR1 | early growth response 1 | -0.0243674 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.024294 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0242353 |
| TUBA1C | tubulin, alpha 1c | -0.0239978 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0239635 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0235781 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0234869 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0228047 |
| TPM4 | tropomyosin 4 | -0.0223015 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0221193 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0221109 |
| RHOA | ras homolog family member A | -0.0220577 |
| CDK14 | cyclin-dependent kinase 14 | -0.0220197 |
| MRC2 | mannose receptor, C type 2 | -0.0219732 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0219215 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0219096 |
| DNER | delta/notch-like EGF repeat containing | -0.0218004 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0217137 |
| TUBA1B | tubulin, alpha 1b | -0.0216179 |
| INSIG2 | insulin induced gene 2 | -0.0212917 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0211548 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | -0.0211036 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.020957 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0209192 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0208969 |
| NAV3 | neuron navigator 3 | -0.0208158 |
| JUN | jun proto-oncogene | -0.0207454 |
