| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pasireotide (acetate) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pasireotide (acetate)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.308683 |
| NDRG1 | N-myc downstream regulated 1 | 0.135923 |
| VEGFA | vascular endothelial growth factor A | 0.117066 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.110465 |
| CDH13 | cadherin 13 | 0.0795604 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0702878 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0658318 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.055145 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0532459 |
| GOLGB1 | golgin B1 | 0.049257 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0412837 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0400472 |
| ASPH | aspartate beta-hydroxylase | 0.0387457 |
| DST | dystonin | 0.0373588 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.032871 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0302423 |
| CADM1 | cell adhesion molecule 1 | 0.0302415 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0300221 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0297693 |
| MYO10 | myosin X | 0.0280485 |
| EFNA5 | ephrin-A5 | 0.0278906 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0277498 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0273571 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0271639 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0263567 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0259976 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0252151 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0251849 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.025039 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0249123 |
| RND3 | Rho family GTPase 3 | 0.0248913 |
| RUNX1 | runt-related transcription factor 1 | 0.0248842 |
| RPS6 | ribosomal protein S6 | 0.0243853 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0242204 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0240845 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0234072 |
| MSN | moesin | 0.023127 |
| HDAC9 | histone deacetylase 9 | 0.0225979 |
| FNIP1 | folliculin interacting protein 1 | 0.0225394 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0214857 |
| CLMP | CXADR-like membrane protein | 0.0210611 |
| BRD2 | bromodomain containing 2 | 0.0202664 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0200382 |
| CALD1 | caldesmon 1 | 0.0199955 |
| ATXN1 | ataxin 1 | 0.0196708 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0195276 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0194802 |
| FMNL2 | formin-like 2 | 0.0194293 |
| EGFR | epidermal growth factor receptor | 0.0192864 |
| VMP1 | vacuole membrane protein 1 | 0.0185472 |
| PDE10A | phosphodiesterase 10A | 0.0184728 |
| FBN1 | fibrillin 1 | 0.0184596 |
| STC2 | stanniocalcin 2 | 0.0175439 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0171686 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0171214 |
| TMF1 | TATA element modulatory factor 1 | 0.0170435 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0170115 |
| PGM3 | phosphoglucomutase 3 | 0.0169714 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0168157 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0166745 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0166541 |
| COL5A1 | collagen, type V, alpha 1 | 0.0165434 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0165158 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0164425 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0163273 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0162531 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0159828 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0159532 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0153078 |
| CUX1 | cut-like homeobox 1 | 0.0148629 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0148134 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0146772 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0145439 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0145358 |
| TPM3 | tropomyosin 3 | 0.0145002 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0144937 |
| SDC2 | syndecan 2 | 0.0144572 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0144376 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0143376 |
| RPL3 | ribosomal protein L3 | 0.0140059 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0137825 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.013726 |
| JUN | jun proto-oncogene | 0.0136454 |
| ATF4 | activating transcription factor 4 | 0.0136224 |
| EXOC4 | exocyst complex component 4 | 0.0135976 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.013566 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0134181 |
| CCNY | cyclin Y | 0.0133761 |
| DOCK7 | dedicator of cytokinesis 7 | 0.0132766 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0132134 |
| MTDH | metadherin | 0.0130203 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0129942 |
| ANO10 | anoctamin 10 | 0.0129756 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0129709 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.012946 |
| SFTPA2 | surfactant protein A2 | 0.0129242 |
| PTK2 | protein tyrosine kinase 2 | 0.0128045 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0128041 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0127645 |
| COPA | coatomer protein complex, subunit alpha | 0.0127602 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.330454 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.194736 |
| COL1A1 | collagen, type I, alpha 1 | -0.142108 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.081883 |
| CD44 | CD44 molecule (Indian blood group) | -0.069697 |
| MT2A | metallothionein 2A | -0.0683985 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0612475 |
| VIM | vimentin | -0.0599051 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0514346 |
| TMSB10 | thymosin beta 10 | -0.050333 |
| LDHA | lactate dehydrogenase A | -0.0403989 |
| IER3 | immediate early response 3 | -0.0393628 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0370226 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.035795 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0357017 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.03519 |
| PTMA | prothymosin, alpha | -0.0349495 |
| POSTN | periostin, osteoblast specific factor | -0.034188 |
| RPL35A | ribosomal protein L35a | -0.0337188 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0334848 |
| STC1 | stanniocalcin 1 | -0.0334589 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0332666 |
| CANX | calnexin | -0.0332572 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0330286 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0328833 |
| LOXL2 | lysyl oxidase-like 2 | -0.0324488 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0300424 |
| ATP13A3 | ATPase type 13A3 | -0.029882 |
| LMAN1 | lectin, mannose-binding, 1 | -0.029191 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0286684 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0273826 |
| SMAD3 | SMAD family member 3 | -0.0268795 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0258567 |
| TMSB4X | thymosin beta 4, X-linked | -0.0256412 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0254068 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0245264 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0230501 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0228039 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0227612 |
| LOX | lysyl oxidase | -0.0226921 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0225692 |
| SRGN | serglycin | -0.022417 |
| COL1A2 | collagen, type I, alpha 2 | -0.0220249 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0219517 |
| FTL | ferritin, light polypeptide | -0.021603 |
| HLA-B | major histocompatibility complex, class I, B | -0.0208876 |
| ACTG1 | actin gamma 1 | -0.0208309 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0204522 |
| SPAG9 | sperm associated antigen 9 | -0.0202151 |
| OSMR | oncostatin M receptor | -0.0199571 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0199011 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0192256 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0188616 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.0186632 |
| ANXA2 | annexin A2 | -0.0184388 |
| TUBB | tubulin, beta class I | -0.0180554 |
| RACK1 | receptor for activated C kinase 1 | -0.0179508 |
| CAVIN1 | caveolae associated protein 1 | -0.0178719 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0178071 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.017466 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0174479 |
| TPM4 | tropomyosin 4 | -0.0173452 |
| CALR | calreticulin | -0.0173066 |
| ACTN4 | actinin, alpha 4 | -0.0173046 |
| ZNF292 | zinc finger protein 292 | -0.0172813 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0171603 |
| RPS24 | ribosomal protein S24 | -0.0171262 |
| KLF6 | Kruppel-like factor 6 | -0.0169434 |
| PXDN | peroxidasin | -0.0168839 |
| FLNA | filamin A, alpha | -0.0168002 |
| COL3A1 | collagen, type III, alpha 1 | -0.0167336 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0167222 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0165896 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0164066 |
| COL12A1 | collagen, type XII, alpha 1 | -0.016088 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0158163 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0158148 |
| INHBA | inhibin, beta A | -0.0155427 |
| RRBP1 | ribosome binding protein 1 | -0.0155271 |
| RPL30 | ribosomal protein L30 | -0.0154313 |
| ARF1 | ADP-ribosylation factor 1 | -0.0151785 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0150785 |
| RPL11 | ribosomal protein L11 | -0.0148146 |
| MX2 | MX dynamin-like GTPase 2 | -0.0146055 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0143619 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0142883 |
| CLIC4 | chloride intracellular channel 4 | -0.0142536 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0141714 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0141421 |
| HDLBP | high density lipoprotein binding protein | -0.0140323 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0140079 |
| RPL7 | ribosomal protein L7 | -0.0139883 |
| TMEM123 | transmembrane protein 123 | -0.013905 |
| FSTL1 | follistatin-like 1 | -0.0138442 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0138049 |
| MT1X | metallothionein 1X | -0.013536 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0133701 |
| PLSCR1 | phospholipid scramblase 1 | -0.0130889 |
| RPL12 | ribosomal protein L12 | -0.0130472 |
| LMNA | lamin A/C | -0.0130326 |
