| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pasireotide (acetate) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pasireotide (acetate)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AHNAK | AHNAK nucleoprotein | 0.106312 |
| KRT8 | keratin 8, type II | 0.0982532 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0908258 |
| INTS6 | integrator complex subunit 6 | 0.0794287 |
| KRT18 | keratin 18, type I | 0.0683398 |
| SMAD3 | SMAD family member 3 | 0.0657187 |
| ASPH | aspartate beta-hydroxylase | 0.0624675 |
| SLC45A4 | solute carrier family 45, member 4 | 0.0592209 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0588688 |
| CTBP2 | C-terminal binding protein 2 | 0.0574345 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0556975 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0554122 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0505681 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0491733 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0471946 |
| NTN4 | netrin 4 | 0.0449838 |
| PRR5L | proline rich 5 like | 0.0449837 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0435307 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0423425 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0418919 |
| RPS6 | ribosomal protein S6 | 0.0405792 |
| FOXO3 | forkhead box O3 | 0.0397232 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0389527 |
| LAMB3 | laminin, beta 3 | 0.0381904 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0381432 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0375427 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0365738 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0365243 |
| RNF213 | ring finger protein 213 | 0.0360111 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0354418 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0352505 |
| GSN | gelsolin | 0.0350613 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.035002 |
| KRT19 | keratin 19, type I | 0.0348428 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0346034 |
| LMO7 | LIM domain 7 | 0.0341875 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0335045 |
| MCL1 | myeloid cell leukemia 1 | 0.0329998 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0322053 |
| VEGFA | vascular endothelial growth factor A | 0.0321843 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0320366 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.031426 |
| KRT20 | keratin 20, type I | 0.030196 |
| DSPP | dentin sialophosphoprotein | 0.029596 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0291493 |
| TXNIP | thioredoxin interacting protein | 0.0282533 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.028092 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0280135 |
| PLEC | plectin | 0.0278367 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0277596 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0274716 |
| ACTN4 | actinin, alpha 4 | 0.0271485 |
| POF1B | premature ovarian failure, 1B | 0.0269657 |
| RNASET2 | ribonuclease T2 | 0.0268174 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.026363 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0261893 |
| PLK2 | polo-like kinase 2 | 0.0261197 |
| MSN | moesin | 0.025876 |
| MYO10 | myosin X | 0.0258697 |
| SERTAD2 | SERTA domain containing 2 | 0.0257176 |
| RPL18 | ribosomal protein L18 | 0.0252952 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0251507 |
| LMNA | lamin A/C | 0.0250062 |
| MYO5B | myosin VB | 0.0247819 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0246396 |
| PRELID2 | PRELI domain containing 2 | 0.0244648 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0243931 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.024393 |
| MKI67 | marker of proliferation Ki-67 | 0.0243176 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.024155 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0235505 |
| APOL1 | apolipoprotein L, 1 | 0.0235057 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0231466 |
| EPS8L1 | EPS8-like 1 | 0.0231184 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0230332 |
| RRBP1 | ribosome binding protein 1 | 0.022898 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0228355 |
| MMP7 | matrix metallopeptidase 7 | 0.0226488 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0224405 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 | 0.0223765 |
| USP53 | ubiquitin specific peptidase 53 | 0.0219838 |
| NABP1 | nucleic acid binding protein 1 | 0.0215687 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0213802 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0207984 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0206581 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0203073 |
| H1-4 | H1.4 linker histone, cluster member | 0.0202265 |
| SDC4 | syndecan 4 | 0.0201395 |
| CCNYL1 | cyclin Y-like 1 | 0.0201076 |
| MTMR10 | myotubularin related protein 10 | 0.0200574 |
| FBXO11 | F-box protein 11 | 0.0198358 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0198104 |
| MIDN | midnolin | 0.0197428 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0197424 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.0196518 |
| RPL3 | ribosomal protein L3 | 0.0195746 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0194484 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0193094 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0192798 |
| DSG2 | desmoglein 2 | 0.0190718 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.203332 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.105026 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0945575 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0856422 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.078606 |
| RPLP1 | ribosomal protein, large, P1 | -0.0754692 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0718783 |
| RPL35A | ribosomal protein L35a | -0.0690391 |
| TXNRD1 | thioredoxin reductase 1 | -0.068182 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0663869 |
| RPL27A | ribosomal protein L27a | -0.0611421 |
| JMJD1C | jumonji domain containing 1C | -0.0566181 |
| RPL31 | ribosomal protein L31 | -0.0537651 |
| LDHA | lactate dehydrogenase A | -0.0534876 |
| RPS13 | ribosomal protein S13 | -0.0514272 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0491975 |
| TMC5 | transmembrane channel-like 5 | -0.0490836 |
| RPS25 | ribosomal protein S25 | -0.0488557 |
| LYZ | lysozyme | -0.04816 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0479313 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0461812 |
| POTEF | POTE ankyrin domain family, member F | -0.0460355 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0452671 |
| NF1 | neurofibromin 1 | -0.0449118 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0446648 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0442673 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0425486 |
| RPLP0 | ribosomal protein, large, P0 | -0.0391304 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0386856 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0386396 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0382004 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0374636 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0374354 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0360493 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.035735 |
| EXPH5 | exophilin 5 | -0.0355947 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0346905 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0345828 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.03453 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0338215 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0329382 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0326502 |
| ARHGAP42 | Rho GTPase activating protein 42 | -0.0325737 |
| NDRG1 | N-myc downstream regulated 1 | -0.0324338 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0315897 |
| RPL39 | ribosomal protein L39 | -0.031436 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0308081 |
| HMGA1 | high mobility group AT-hook 1 | -0.0308011 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0306206 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0306181 |
| TPM4 | tropomyosin 4 | -0.0305787 |
| RPS24 | ribosomal protein S24 | -0.0305046 |
| AGR2 | anterior gradient 2 | -0.0302928 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0300444 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0299963 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0296437 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0295497 |
| PTMA | prothymosin, alpha | -0.0294343 |
| RPL37A | ribosomal protein L37a | -0.0293617 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0286726 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0285023 |
| RPS16 | ribosomal protein S16 | -0.0282169 |
| RPS5 | ribosomal protein S5 | -0.0280098 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.0279146 |
| FHL2 | four and a half LIM domains 2 | -0.0277993 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0275235 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0272404 |
| RPL11 | ribosomal protein L11 | -0.0272112 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0270892 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0264625 |
| PLA2R1 | phospholipase A2 receptor 1, 180kDa | -0.0264353 |
| FAM91A1 | family with sequence similarity 91, member A1 | -0.0263803 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0263445 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0261316 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | -0.0260767 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0259216 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0257733 |
| ANXA11 | annexin A11 | -0.0256518 |
| TJP1 | tight junction protein 1 | -0.0256378 |
| WDR45B | WD repeat domain 45B | -0.0254411 |
| RPL30 | ribosomal protein L30 | -0.0253 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0251195 |
| ENO1 | enolase 1, (alpha) | -0.0249738 |
| RPS20 | ribosomal protein S20 | -0.0249732 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0249139 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0248505 |
| SELENOS | selenoprotein S | -0.0245663 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0245065 |
| KLHL24 | kelch-like family member 24 | -0.0242145 |
| RPLP2 | ribosomal protein, large, P2 | -0.024118 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0240816 |
| RPS14 | ribosomal protein S14 | -0.0240067 |
| HM13 | histocompatibility (minor) 13 | -0.0237868 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0237333 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0236561 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0233035 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0232437 |
| RPL13A | ribosomal protein L13a | -0.0229898 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0229767 |
| NUP58 | nucleoporin 58 | -0.0229405 |
