| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pasireotide (acetate) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pasireotide (acetate)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.137957 |
| MT2A | metallothionein 2A | 0.106578 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0988964 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0978836 |
| INTS6 | integrator complex subunit 6 | 0.096957 |
| ERBIN | erbb2 interacting protein | 0.0924249 |
| DST | dystonin | 0.0885537 |
| NAV2 | neuron navigator 2 | 0.0874262 |
| ASPH | aspartate beta-hydroxylase | 0.0866691 |
| AHNAK | AHNAK nucleoprotein | 0.083568 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0827694 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0806736 |
| RPS6 | ribosomal protein S6 | 0.0787091 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0727446 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0630513 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0603722 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0587226 |
| MKI67 | marker of proliferation Ki-67 | 0.058188 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.058027 |
| MSN | moesin | 0.0538957 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0510838 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0507156 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0506482 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0497436 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0475713 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0455292 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0454439 |
| GOLGA4 | golgin A4 | 0.0437518 |
| CENPF | centromere protein F, 350/400kDa | 0.0433588 |
| TPM3 | tropomyosin 3 | 0.0428701 |
| TLE4 | transducin-like enhancer of split 4 | 0.0428483 |
| YBX1 | Y box binding protein 1 | 0.0428118 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0415329 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0408377 |
| TMSB10 | thymosin beta 10 | 0.0405285 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0399655 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0395358 |
| FNIP1 | folliculin interacting protein 1 | 0.0395276 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0385951 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0381432 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0369334 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0369196 |
| PRELID2 | PRELI domain containing 2 | 0.0362773 |
| GOLGB1 | golgin B1 | 0.0361152 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0354578 |
| CORO1C | coronin, actin binding protein, 1C | 0.03541 |
| PTK2 | protein tyrosine kinase 2 | 0.0350909 |
| NSD2 | nuclear receptor binding SET domain protein 2 | 0.0350556 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.035004 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0349351 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0347896 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0347522 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0346981 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0342202 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0338933 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0337304 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0337006 |
| VEGFA | vascular endothelial growth factor A | 0.0336953 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0333882 |
| CTBP2 | C-terminal binding protein 2 | 0.0332085 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0331147 |
| RPLP2 | ribosomal protein, large, P2 | 0.03148 |
| ACTN1 | actinin, alpha 1 | 0.0314713 |
| RPL23 | ribosomal protein L23 | 0.031451 |
| SMYD3 | SET and MYND domain containing 3 | 0.0311846 |
| BRD2 | bromodomain containing 2 | 0.0310157 |
| ATXN1 | ataxin 1 | 0.0309886 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0308817 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0306617 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0305995 |
| STC2 | stanniocalcin 2 | 0.0305643 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0304768 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0303856 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0303303 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0301616 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.030145 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0301106 |
| NDRG1 | N-myc downstream regulated 1 | 0.0300916 |
| CLIC4 | chloride intracellular channel 4 | 0.0300835 |
| RPL19 | ribosomal protein L19 | 0.0297869 |
| TPX2 | TPX2, microtubule-associated | 0.0289885 |
| PKM | pyruvate kinase, muscle | 0.0289146 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0287988 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0285654 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0284814 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0284412 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0284119 |
| MT1X | metallothionein 1X | 0.0280963 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0280585 |
| DIAPH3 | diaphanous-related formin 3 | 0.0280317 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0277504 |
| RPL35A | ribosomal protein L35a | 0.0277158 |
| MAP4 | microtubule-associated protein 4 | 0.0271828 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0270542 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0269478 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0267435 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0266256 |
| WNT5B | wingless-type MMTV integration site family, member 5B | 0.0265796 |
| CALD1 | caldesmon 1 | 0.0265105 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0263856 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD44 | CD44 molecule (Indian blood group) | -0.0781774 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0746193 |
| SLC12A8 | solute carrier family 12, member 8 | -0.0738863 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.064413 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0587589 |
| FN1 | fibronectin 1 | -0.0555247 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0471176 |
| HLA-B | major histocompatibility complex, class I, B | -0.0453657 |
| GLIS3 | GLIS family zinc finger 3 | -0.0409015 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0403607 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0382108 |
| LOC112694756 | uncharaterized LOC112694756 | -0.03301 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0323316 |
| OSMR | oncostatin M receptor | -0.0319835 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0311103 |
| POSTN | periostin, osteoblast specific factor | -0.0299324 |
| ATP13A3 | ATPase type 13A3 | -0.0294202 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0292489 |
| TUBB | tubulin, beta class I | -0.028164 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0273902 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0264033 |
| CTSD | cathepsin D | -0.0258946 |
| TMSB4X | thymosin beta 4, X-linked | -0.0257987 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0252904 |
| TXNRD1 | thioredoxin reductase 1 | -0.0248631 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0245182 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0239623 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0238675 |
| ADM | adrenomedullin | -0.0236252 |
| ARF4 | ADP-ribosylation factor 4 | -0.0232958 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0219298 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0215918 |
| TUBA1C | tubulin, alpha 1c | -0.0209929 |
| KPNB1 | karyopherin (importin) beta 1 | -0.020392 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0202378 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0201112 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0198091 |
| S100A6 | S100 calcium binding protein A6 | -0.019445 |
| SULF1 | sulfatase 1 | -0.0193478 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0193438 |
| TUBA1B | tubulin, alpha 1b | -0.0189908 |
| ANXA1 | annexin A1 | -0.0188961 |
| HLA-C | major histocompatibility complex, class I, C | -0.018838 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0183842 |
| LOX | lysyl oxidase | -0.0181876 |
| LDHA | lactate dehydrogenase A | -0.018031 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0175834 |
| GOLT1B | golgi transport 1B | -0.0172179 |
| AFAP1 | actin filament associated protein 1 | -0.0169859 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0169717 |
| COLEC10 | collectin sub-family member 10 (C-type lectin) | -0.01654 |
| WDR45B | WD repeat domain 45B | -0.0164906 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0163377 |
| FSTL1 | follistatin-like 1 | -0.0163296 |
| FTL | ferritin, light polypeptide | -0.0161274 |
| TMEM41B | transmembrane protein 41B | -0.0160689 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0159418 |
| RNF144B | ring finger protein 144B | -0.0159351 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0158015 |
| HLA-E | major histocompatibility complex, class I, E | -0.0157367 |
| LMAN1 | lectin, mannose-binding, 1 | -0.01562 |
| ARF1 | ADP-ribosylation factor 1 | -0.0155454 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0151952 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | -0.0148185 |
| SEPTIN7 | septin 7 | -0.0147696 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0146003 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0141709 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0141614 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.014042 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0140322 |
| IER3 | immediate early response 3 | -0.0139791 |
| TMEM178B | transmembrane protein 178B | -0.0138913 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0138575 |
| PLIN2 | perilipin 2 | -0.0137023 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0132923 |
| PPME1 | protein phosphatase methylesterase 1 | -0.0132072 |
| ANAPC5 | anaphase promoting complex subunit 5 | -0.0131915 |
| LAMP1 | lysosomal-associated membrane protein 1 | -0.0131878 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 | -0.0130802 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | -0.0130135 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0127995 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0127764 |
| PGK1 | phosphoglycerate kinase 1 | -0.0127733 |
| SRP54 | signal recognition particle 54kDa | -0.0127267 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0126682 |
| TRAM2 | translocation associated membrane protein 2 | -0.0124038 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0124028 |
| POLE3 | polymerase (DNA directed), epsilon 3, accessory subunit | -0.0123942 |
| GNS | glucosamine (N-acetyl)-6-sulfatase | -0.0123173 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0121931 |
| TFG | TRK-fused gene | -0.0121779 |
| SURF4 | surfeit 4 | -0.0121356 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | -0.0120378 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0120287 |
| NUP155 | nucleoporin 155kDa | -0.0117387 |
| PSG9 | pregnancy specific beta-1-glycoprotein 9 | -0.0117134 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0115389 |
| SEC24A | SEC24 family member A | -0.0115295 |
| IL6 | interleukin 6 | -0.0115168 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0114668 |