| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pasireotide (acetate) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pasireotide (acetate)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS6 | ribosomal protein S6 | 0.177319 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.134786 |
| ASPH | aspartate beta-hydroxylase | 0.126408 |
| LMO7 | LIM domain 7 | 0.125122 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.111412 |
| DSPP | dentin sialophosphoprotein | 0.109624 |
| CENPF | centromere protein F, 350/400kDa | 0.0937438 |
| KRT18 | keratin 18, type I | 0.0922417 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0908333 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0888081 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0873281 |
| FAT1 | FAT atypical cadherin 1 | 0.0855806 |
| VEGFA | vascular endothelial growth factor A | 0.082083 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0816244 |
| TPM3 | tropomyosin 3 | 0.0771599 |
| ITGA6 | integrin, alpha 6 | 0.0762344 |
| KRT8 | keratin 8, type II | 0.0671181 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0662197 |
| GOLGB1 | golgin B1 | 0.0650886 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0616183 |
| RPL3 | ribosomal protein L3 | 0.0603162 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.059105 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0577136 |
| RPS2 | ribosomal protein S2 | 0.0565102 |
| MT2A | metallothionein 2A | 0.055999 |
| YBX1 | Y box binding protein 1 | 0.0541339 |
| GOLGA4 | golgin A4 | 0.0529619 |
| SLK | STE20-like kinase | 0.052404 |
| RPS8 | ribosomal protein S8 | 0.0516635 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0502649 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0492483 |
| H1-4 | H1.4 linker histone, cluster member | 0.0481766 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0478742 |
| KIF5B | kinesin family member 5B | 0.0462823 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0456315 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0445934 |
| RPS12 | ribosomal protein S12 | 0.0440997 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0436074 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0420511 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0415734 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0405365 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0395913 |
| CALR | calreticulin | 0.0386219 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0376891 |
| EHF | ets homologous factor | 0.0376164 |
| MKI67 | marker of proliferation Ki-67 | 0.0374763 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0367774 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.03589 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.03585 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0356203 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0350168 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0347726 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0344835 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.034016 |
| TMF1 | TATA element modulatory factor 1 | 0.0339793 |
| SON | SON DNA binding protein | 0.0338894 |
| DSG2 | desmoglein 2 | 0.0334151 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0326726 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0321926 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0320201 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.031781 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0315569 |
| AHNAK | AHNAK nucleoprotein | 0.031133 |
| SET | SET nuclear proto-oncogene | 0.0300344 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.029554 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0292391 |
| PDZD8 | PDZ domain containing 8 | 0.0290552 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0290076 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.028996 |
| SVIL | supervillin | 0.0288513 |
| RPS19 | ribosomal protein S19 | 0.0281196 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0276095 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0274833 |
| ABHD2 | abhydrolase domain containing 2 | 0.0271494 |
| CENPE | centromere protein E, 312kDa | 0.0269989 |
| EZR | ezrin | 0.0269775 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0269269 |
| MT1X | metallothionein 1X | 0.0267629 |
| PLS1 | plastin 1 | 0.0264542 |
| RPL36 | ribosomal protein L36 | 0.0262647 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0260306 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0259395 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.025925 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0256478 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.025576 |
| PCM1 | pericentriolar material 1 | 0.0255238 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0253719 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0253659 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0251349 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0248368 |
| TXNRD1 | thioredoxin reductase 1 | 0.0247603 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.0246607 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0244306 |
| PNN | pinin, desmosome associated protein | 0.0244041 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0243818 |
| RPL21 | ribosomal protein L21 | 0.024184 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0237753 |
| MT1E | metallothionein 1E | 0.0236639 |
| TPI1 | triosephosphate isomerase 1 | 0.0235422 |
| DST | dystonin | 0.0234404 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.195458 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.126488 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.11123 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.107416 |
| VCL | vinculin | -0.107223 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.104343 |
| PIGR | polymeric immunoglobulin receptor | -0.0920705 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0893024 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0859317 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0845381 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0797027 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.069033 |
| GPHN | gephyrin | -0.0660494 |
| MYO1E | myosin IE | -0.0655425 |
| RPS24 | ribosomal protein S24 | -0.0603203 |
| MUC17 | mucin 17, cell surface associated | -0.0570606 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0537154 |
| RPLP0 | ribosomal protein, large, P0 | -0.0528856 |
| ACTN4 | actinin, alpha 4 | -0.0522092 |
| RPL35A | ribosomal protein L35a | -0.0514144 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0479917 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0454151 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0421741 |
| IER3 | immediate early response 3 | -0.0403926 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0395602 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0389996 |
| TMSB10 | thymosin beta 10 | -0.0388037 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0378158 |
| DENND1A | DENN/MADD domain containing 1A | -0.0375761 |
| ITGB4 | integrin, beta 4 | -0.0375285 |
| FAM13A | family with sequence similarity 13, member A | -0.0374135 |
| LAMA4 | laminin, alpha 4 | -0.0369969 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0359939 |
| PRELID2 | PRELI domain containing 2 | -0.0359567 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0356421 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0351682 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0351669 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0349301 |
| EGR1 | early growth response 1 | -0.0347597 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0344132 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0343693 |
| S100A6 | S100 calcium binding protein A6 | -0.0343308 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0339717 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0328639 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.032172 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0314714 |
| TMEM123 | transmembrane protein 123 | -0.0312843 |
| NFIA | nuclear factor I/A | -0.0309681 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0308598 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0307273 |
| INSIG1 | insulin induced gene 1 | -0.0306406 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0303819 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0295806 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0291814 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0289398 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0287613 |
| PALLD | palladin, cytoskeletal associated protein | -0.0285704 |
| TNS4 | tensin 4 | -0.0285245 |
| CCNY | cyclin Y | -0.0284633 |
| POF1B | premature ovarian failure, 1B | -0.0278044 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0276396 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0269334 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0268086 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0267899 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0265112 |
| FHIT | fragile histidine triad | -0.0262975 |
| FLNB | filamin B, beta | -0.0259353 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0258629 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0257155 |
| FERMT1 | fermitin family member 1 | -0.025335 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0252796 |
| CALB1 | calbindin 1, 28kDa | -0.0251727 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | -0.0251166 |
| TFRC | transferrin receptor | -0.0251105 |
| WDR45B | WD repeat domain 45B | -0.0251044 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0250728 |
| GDF15 | growth differentiation factor 15 | -0.0250388 |
| FHL2 | four and a half LIM domains 2 | -0.0249592 |
| ANXA2 | annexin A2 | -0.0248836 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0246067 |
| RPS25 | ribosomal protein S25 | -0.0245702 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0243465 |
| FDPS | farnesyl diphosphate synthase | -0.0241191 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0239872 |
| PTMA | prothymosin, alpha | -0.0239391 |
| DIAPH2 | diaphanous-related formin 2 | -0.0238568 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0237642 |
| ABLIM1 | actin binding LIM protein 1 | -0.0237368 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0234144 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0230263 |
| ARF1 | ADP-ribosylation factor 1 | -0.0228672 |
| KLF6 | Kruppel-like factor 6 | -0.0228166 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0226903 |
| AGR2 | anterior gradient 2 | -0.0225592 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0225006 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0223716 |
| FOSL1 | FOS-like antigen 1 | -0.0223125 |
| HMGA1 | high mobility group AT-hook 1 | -0.022233 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.0221657 |
| RPL27A | ribosomal protein L27a | -0.022134 |
