| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pasireotide (acetate) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pasireotide (acetate)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS6 | ribosomal protein S6 | 0.161356 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.153511 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.131925 |
| RPL3 | ribosomal protein L3 | 0.101116 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0814732 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0754275 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0678895 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0661469 |
| TPM3 | tropomyosin 3 | 0.0608007 |
| ASPH | aspartate beta-hydroxylase | 0.0605719 |
| EZR | ezrin | 0.0595815 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0595671 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0594593 |
| YBX1 | Y box binding protein 1 | 0.0561396 |
| ITGA6 | integrin, alpha 6 | 0.0559644 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.054919 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0533702 |
| MKI67 | marker of proliferation Ki-67 | 0.0528408 |
| TXNRD1 | thioredoxin reductase 1 | 0.051891 |
| GOLGA4 | golgin A4 | 0.0472201 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0467503 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0461965 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0453248 |
| GOLGB1 | golgin B1 | 0.0449439 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.044841 |
| KRT18 | keratin 18, type I | 0.043809 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0416178 |
| RPL4 | ribosomal protein L4 | 0.0414951 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.041157 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0409451 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0407644 |
| RPS19 | ribosomal protein S19 | 0.0406312 |
| TMF1 | TATA element modulatory factor 1 | 0.0395602 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0395442 |
| DST | dystonin | 0.0390984 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.039028 |
| LMO7 | LIM domain 7 | 0.0389049 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.038227 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0372392 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0362597 |
| RPS12 | ribosomal protein S12 | 0.0355234 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0354521 |
| RNF145 | ring finger protein 145 | 0.0331813 |
| PRSS3 | protease, serine, 3 | 0.0331258 |
| MT2A | metallothionein 2A | 0.0330084 |
| SLK | STE20-like kinase | 0.0320073 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0315429 |
| PKM | pyruvate kinase, muscle | 0.0314477 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0310754 |
| RPS2 | ribosomal protein S2 | 0.0309832 |
| SAMD5 | sterile alpha motif domain containing 5 | 0.0307771 |
| CORO1C | coronin, actin binding protein, 1C | 0.0305056 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0301915 |
| RPL14 | ribosomal protein L14 | 0.0300414 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0298682 |
| PCBP2 | poly(rC) binding protein 2 | 0.0294175 |
| DSPP | dentin sialophosphoprotein | 0.0290662 |
| TXNIP | thioredoxin interacting protein | 0.028717 |
| PDZD8 | PDZ domain containing 8 | 0.0287064 |
| TNRC18 | trinucleotide repeat containing 18 | 0.028357 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0280367 |
| NDRG1 | N-myc downstream regulated 1 | 0.0275114 |
| BCL2L1 | BCL2-like 1 | 0.0271897 |
| RPL8 | ribosomal protein L8 | 0.0270627 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0269756 |
| SON | SON DNA binding protein | 0.0269722 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.026835 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0267452 |
| RRBP1 | ribosome binding protein 1 | 0.0267424 |
| CTBP2 | C-terminal binding protein 2 | 0.0265859 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0261985 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0259497 |
| RPL36 | ribosomal protein L36 | 0.0255554 |
| DSG2 | desmoglein 2 | 0.0255096 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0254936 |
| WWOX | WW domain containing oxidoreductase | 0.0254506 |
| DIAPH1 | diaphanous-related formin 1 | 0.0254468 |
| VEGFA | vascular endothelial growth factor A | 0.0247554 |
| BRD2 | bromodomain containing 2 | 0.0245891 |
| RPS18 | ribosomal protein S18 | 0.0245648 |
| UBE3A | ubiquitin protein ligase E3A | 0.0245255 |
| PCM1 | pericentriolar material 1 | 0.024485 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0244578 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0242863 |
| NRDC | nardilysin convertase | 0.0240388 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0240273 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0238706 |
| KIF5B | kinesin family member 5B | 0.0236516 |
| PNN | pinin, desmosome associated protein | 0.0236377 |
| TMEM45B | transmembrane protein 45B | 0.0236142 |
| RNF43 | ring finger protein 43 | 0.0236024 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0233876 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 | 0.0231535 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0231126 |
| MYO10 | myosin X | 0.023057 |
| KDM5A | lysine (K)-specific demethylase 5A | 0.0229307 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0226513 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0226378 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.022473 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0224044 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.247037 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.151143 |
| RPLP0 | ribosomal protein, large, P0 | -0.133817 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0941712 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0903388 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0877585 |
| RPS24 | ribosomal protein S24 | -0.0838242 |
| MYO1E | myosin IE | -0.0810732 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.076622 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0759711 |
| VCL | vinculin | -0.0730431 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0700397 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0693375 |
| INTS6 | integrator complex subunit 6 | -0.0660493 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0637521 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0619247 |
| LAMB3 | laminin, beta 3 | -0.0616522 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0604595 |
| RPS25 | ribosomal protein S25 | -0.0603587 |
| RPL34 | ribosomal protein L34 | -0.0599095 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0579523 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0573398 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0560233 |
| PLAC8 | placenta-specific 8 | -0.05539 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.054884 |
| ACTG1 | actin gamma 1 | -0.0540527 |
| EXT1 | exostosin glycosyltransferase 1 | -0.053771 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0525699 |
| ACTN4 | actinin, alpha 4 | -0.0520456 |
| ANXA2 | annexin A2 | -0.0495193 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.0483427 |
| MSI2 | musashi RNA-binding protein 2 | -0.0479991 |
| RPL9 | ribosomal protein L9 | -0.0472917 |
| RPL27A | ribosomal protein L27a | -0.0464706 |
| RPL30 | ribosomal protein L30 | -0.0460165 |
| LRRC23 | leucine rich repeat containing 23 | -0.0452783 |
| TSPAN8 | tetraspanin 8 | -0.0445264 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0429332 |
| RPL31 | ribosomal protein L31 | -0.0427586 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0421852 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0416554 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0413646 |
| LDHA | lactate dehydrogenase A | -0.0412269 |
| HLA-B | major histocompatibility complex, class I, B | -0.0401927 |
| GDF15 | growth differentiation factor 15 | -0.0395142 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.0385105 |
| RPL35A | ribosomal protein L35a | -0.0380593 |
| AOPEP | aminopeptidase O (putative) | -0.0378465 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.037551 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0374828 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | -0.0359993 |
| S100A6 | S100 calcium binding protein A6 | -0.0355831 |
| RPS16 | ribosomal protein S16 | -0.0354767 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.03525 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0350933 |
| PRELID2 | PRELI domain containing 2 | -0.0346376 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0343102 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0342642 |
| DSG3 | desmoglein 3 | -0.0342076 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0334399 |
| PALLD | palladin, cytoskeletal associated protein | -0.0332047 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0327897 |
| RIGI | RNA sensor RIG-I | -0.0327821 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0324805 |
| SPINK13 | serine peptidase inhibitor, Kazal type 13 (putative) | -0.0322598 |
| CANX | calnexin | -0.0319502 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.03187 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0315036 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0313938 |
| SP100 | SP100 nuclear antigen | -0.0310997 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0308859 |
| PTMA | prothymosin, alpha | -0.0305195 |
| TC2N | tandem C2 domains, nuclear | -0.0303326 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0302857 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0301271 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.029847 |
| RAB1A | RAB1A, member RAS oncogene family | -0.029795 |
| TPTEP2-CSNK1E | TPTEP2-CSNK1E readthrough | -0.0291499 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0289045 |
| AGR2 | anterior gradient 2 | -0.0286834 |
| SQSTM1 | sequestosome 1 | -0.0284923 |
| PIK3AP1 | phosphoinositide-3-kinase adaptor protein 1 | -0.0282705 |
| FRMD5 | FERM domain containing 5 | -0.0281482 |
| RPL39 | ribosomal protein L39 | -0.02795 |
| PERP | PERP, TP53 apoptosis effector | -0.0274635 |
| NFIA | nuclear factor I/A | -0.0272683 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0272162 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0271001 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0269521 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0263479 |
| NPR2 | natriuretic peptide receptor 2 | -0.0263203 |
| SHROOM3 | shroom family member 3 | -0.0261548 |
| IRF1 | interferon regulatory factor 1 | -0.026146 |
| RPS20 | ribosomal protein S20 | -0.0260555 |
| RIN2 | Ras and Rab interactor 2 | -0.0259111 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0254898 |
| RPS13 | ribosomal protein S13 | -0.0254162 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0248673 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0247881 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0245651 |
